Structural basis of cytotoxicity mediated by the type III secretion toxin ExoU from pseudomonas aeruginosa

PLoS Pathogens

Volumn 8, Issue 4, 2012, Pages

  Gendrin, Claire ^a,b,c   Contreras Martel, Carlos ^a,b,c   Bouillot, Stéphanie ^b,c,d,e   Elsen, Sylvie ^b,c,d,e   Lemaire, David ^b,c,f   Skoufias, Dimitrios A ^a,b,c   Huber, Philippe ^b,c,d,e   Attree, Ina ^b,c,d,e   Dessen, Andréa ^a,b,c  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^b DIF   (France)

^c CNRS   (France)

^d UNIV GRENOBLE ALPES   (France)

^e INSERM   (France)

^f AIX MARSEILLE UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; BACTERIAL TOXIN; CHAPERONE; EXOU TOXIN; LIPID; LYSINE; PHOSPHOLIPASE; SPCU TOXIN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PSEUDOMONAS EXOPROTEIN A PROTEIN, PSEUDOMONAS AERUGINOSA; SPCU PROTEIN, PSEUDOMONAS AERUGINOSA;

ARTICLE; CATALYSIS; CONFORMATION; CRYSTAL STRUCTURE; CYTOTOXICITY; ENDOSOME; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; EUKARYOTIC CELL; GENE REARRANGEMENT; GENETIC TRANSFECTION; MEMBRANE BINDING; NONHUMAN; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PSEUDOMONAS AERUGINOSA; STOICHIOMETRY; TYPE III SECRETION SYSTEM; UBIQUITINATION; BACTERIAL SECRETION SYSTEM; CHEMISTRY; HELA CELL; HUMAN; METABOLISM; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE; PSEUDOMONAS INFECTION; STRUCTURE ACTIVITY RELATION;

EUKARYOTA; NEGIBACTERIA; PSEUDOMONAS AERUGINOSA;

BACTERIAL PROTEINS; BACTERIAL SECRETION SYSTEMS; BACTERIAL TOXINS; HELA CELLS; HUMANS; MOLECULAR CHAPERONES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; STRUCTURE-ACTIVITY RELATIONSHIP; UBIQUITINATION;

EID: 84861206143     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002637     Document Type: Article

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