PPARβ/δ ameliorates fructose-induced insulin resistance in adipocytes by preventing Nrf2 activation

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 5, 2015, Pages 1049-1058

  Barroso, Emma ^a,b   Rodríguez Rodríguez, Rosalía ^a   Chacón, Matilde R ^b,c,d   Maymó Masip, Elsa ^b,c,d   Ferrer, Laura ^a   Salvadó, Laia ^a,g   Salmerón, Emilio ^a   Wabistch, Martin ^e   Palomer, Xavier ^a,g   Vendrell, Joan ^b,c,d   Wahli, Walter ^f,g   Vázquez Carrera, Manuel ^a,g  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL UNIVERSITARI JOAN XXIII   (Spain)

^d UNIVERSITAT ROVIRA I VIRGILI   (Spain)

^e UNIVERSITY OF ULM   (Germany)

^f UNIVERSITY OF LAUSANNE   (Switzerland)

^g NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Adipocyte; CD36; Fructose; JNK; Oxidized LDL; PPAR

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; CD36 ANTIGEN; CD68 ANTIGEN; FRUCTOSE; INSULIN; MONOCYTE CHEMOTACTIC PROTEIN 1; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PROTEIN KINASE B; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); STRESS ACTIVATED PROTEIN KINASE; TAP WATER; TRANSCRIPTION FACTOR NRF2; TRIACYLGLYCEROL; TRIGONELLINE; TUMOR NECROSIS FACTOR ALPHA; [2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; ALKALOID; CYTOKINE; LOW DENSITY LIPOPROTEIN; THIAZOLE DERIVATIVE;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CARBOHYDRATE INTAKE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; ENDOPLASMIC RETICULUM STRESS; GENOTYPE; GLUCOSE INTOLERANCE; INFLAMMATION; INSULIN RESISTANCE; LIPOHYPERTROPHY; LIVER; LIVER WEIGHT; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WHITE ADIPOSE TISSUE; 129 MOUSE; 3T3 CELL LINE; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINE; DRUG EFFECTS; GENETICS; HUMAN; IMMUNOBLOTTING; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

MUS;

3T3-L1 CELLS; ADIPOCYTES; ALKALOIDS; ANIMALS; ANTIGENS, CD36; CELL LINE; CYTOKINES; FRUCTOSE; GLUCOSE INTOLERANCE; HUMANS; IMMUNOBLOTTING; INSULIN RESISTANCE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPROTEINS, LDL; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; PPAR DELTA; PPAR-BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THIAZOLES;

EID: 84924135031     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2015.02.010     Document Type: Article

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