TNF-α inhibits PPARβ/δ activity and SIRT1 expression through NF-κB in human adipocytes

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1821, Issue 9, 2012, Pages 1177-1185

  Serrano Marco, Lucía ^a,b   Chacón, Matilde R ^b,c   Maymó Masip, Elsa ^b,c   Barroso, Emma ^a,b   Salvadó, Laia ^a,b   Wabitsch, Martin ^d   Garrido Sánchez, Lourdes ^b,c   Tinahones, Francisco J ^e,f   Palomer, Xavier ^a,b   Vendrell, Joan ^b,c   Vázquez Carrera, Manuel ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL UNIVERSITARI JOAN XXIII   (Spain)

^d UNIVERSITY OF ULM   (Germany)

^e HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

^f Instituto de Salud Carlos III   (Spain)

Author keywords

NF B; PPAR ; SIRT1; TNF

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; DNA; INSULIN; INTERLEUKIN 6; MESSENGER RNA; PARTHENOLIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; SIRTUIN 1; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ADULT; ARTICLE; BINDING AFFINITY; CLINICAL ARTICLE; CONTROLLED STUDY; DNA BINDING; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; INSULIN RESISTANCE; MALE; OBESITY; PRIORITY JOURNAL; RECEPTOR BLOCKING;

ACTIVE TRANSPORT, CELL NUCLEUS; ADIPOCYTES; ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL NUCLEUS; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INFLAMMATION; INTERLEUKIN-6; INTRA-ABDOMINAL FAT; MALE; METABOLIC SYNDROME X; MIDDLE AGED; OBESITY; PPAR DELTA; PPAR-BETA; SESQUITERPENES; SIRTUIN 1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84862301199     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2012.05.006     Document Type: Article

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