메뉴 건너뛰기




Volumn 458, Issue 3, 2015, Pages 707-713

Baicalin and baicalein inhibit transforming growth factor-β1-mediated epithelial-mesenchymal transition in human breast epithelial cells

Author keywords

Baicalein; Baicalin; Breast cancer; Epithelial mesenchymal transition; NF B; Slug

Indexed keywords

BAICALEIN; BAICALIN; CADHERIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NERVE CELL ADHESION MOLECULE; PLANT EXTRACT; SCUTELLARIA BAICALENSIS GEORGI EXTRACT; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UVOMORULIN; ANTINEOPLASTIC AGENT; FLAVANONE DERIVATIVE; FLAVONOID; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 84924080857     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.02.032     Document Type: Article
Times cited : (70)

References (32)
  • 1
    • 83755196813 scopus 로고    scopus 로고
    • Genomics of adjuvant therapy for breast cancer
    • S.R. Kim, and S. Paik Genomics of adjuvant therapy for breast cancer Cancer J. 17 2011 500 504
    • (2011) Cancer J. , vol.17 , pp. 500-504
    • Kim, S.R.1    Paik, S.2
  • 2
    • 75649151387 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer development and its clinical significance
    • M. Iwatsuki, K. Mimori, and T. Yokobori Epithelial-mesenchymal transition in cancer development and its clinical significance Cancer Sci. 101 2010 293 299
    • (2010) Cancer Sci. , vol.101 , pp. 293-299
    • Iwatsuki, M.1    Mimori, K.2    Yokobori, T.3
  • 3
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • J.P. Thiery Epithelial-mesenchymal transitions in tumour progression Nat. Rev. Cancer 2 2002 442 454
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 4
    • 24644487312 scopus 로고    scopus 로고
    • TGF-beta and epithelial-to-mesenchymal transitions
    • J. Zavadil, and E.P. Böttinger TGF-beta and epithelial-to-mesenchymal transitions Oncogene 24 2005 5764 5774
    • (2005) Oncogene , vol.24 , pp. 5764-5774
    • Zavadil, J.1    Böttinger, E.P.2
  • 5
    • 0033377867 scopus 로고    scopus 로고
    • TGF-(beta) type i receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells
    • E. Piek, A. Moustakas, and A. Kurisaki TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells J. Cell. Sci. 112 1999 4557 4568
    • (1999) J. Cell. Sci. , vol.112 , pp. 4557-4568
    • Piek, E.1    Moustakas, A.2    Kurisaki, A.3
  • 6
    • 0036674213 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase is required for TGFbeta-mediated fibroblastic transdifferentiation and cell migration
    • A.V. Bakin, C. Rinehart, and A.K. Tomlinson p38 mitogen-activated protein kinase is required for TGFbeta-mediated fibroblastic transdifferentiation and cell migration J. Cell. Sci. 115 2002 3193 3206
    • (2002) J. Cell. Sci. , vol.115 , pp. 3193-3206
    • Bakin, A.V.1    Rinehart, C.2    Tomlinson, A.K.3
  • 7
    • 0033605704 scopus 로고    scopus 로고
    • Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart
    • C.B. Brown, A.S. Boyer, and R.B. Runyan Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart Science 283 1999 2080 2082
    • (1999) Science , vol.283 , pp. 2080-2082
    • Brown, C.B.1    Boyer, A.S.2    Runyan, R.B.3
  • 8
    • 0031057785 scopus 로고    scopus 로고
    • E-cadherin mediates adhesion and suppresses cell motility via distinct mechanisms
    • H. Chen, N.E. Paradies, and M. Fedor-Chaiken E-cadherin mediates adhesion and suppresses cell motility via distinct mechanisms J. Cell. Sci. 110 Pt3 1997 345 356
    • (1997) J. Cell. Sci. , vol.110 , Issue.PART3 , pp. 345-356
    • Chen, H.1    Paradies, N.E.2    Fedor-Chaiken, M.3
  • 9
    • 37249030356 scopus 로고    scopus 로고
    • A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer
    • K. Gravdal, O.J. Halvorsen, and S.A. Haukaas A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer Clin. Cancer Res. 13 2007 7003 7011
    • (2007) Clin. Cancer Res. , vol.13 , pp. 7003-7011
    • Gravdal, K.1    Halvorsen, O.J.2    Haukaas, S.A.3
  • 10
    • 0035872426 scopus 로고    scopus 로고
    • Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation
    • V. Ellenrieder, S.F. Hendler, and W. Boeck Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation Cancer Res. 61 2001 4222 4228
    • (2001) Cancer Res. , vol.61 , pp. 4222-4228
    • Ellenrieder, V.1    Hendler, S.F.2    Boeck, W.3
  • 11
    • 12544257249 scopus 로고    scopus 로고
    • Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo
    • A.K. Kamaraju, and A.B. Roberts Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo J. Biol. Chem. 280 2005 1024 1036
    • (2005) J. Biol. Chem. , vol.280 , pp. 1024-1036
    • Kamaraju, A.K.1    Roberts, A.B.2
  • 12
    • 33645302628 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition: New insights in signaling, development, and disease
    • J.M. Lee, S. Dedhar, and R. Kalluri The epithelial-mesenchymal transition: new insights in signaling, development, and disease J. Cell. Biol. 72 2006 973 981
    • (2006) J. Cell. Biol. , vol.72 , pp. 973-981
    • Lee, J.M.1    Dedhar, S.2    Kalluri, R.3
  • 13
    • 84871585110 scopus 로고    scopus 로고
    • Baicalein induces apoptosis in esophageal squamous cell carcinoma cells through modulation of the PI3K/Akt pathway
    • H.B. Zhang, P. Lu, and Q.Y. Guo Baicalein induces apoptosis in esophageal squamous cell carcinoma cells through modulation of the PI3K/Akt pathway Oncol. Lett. 5 2013 722 728
    • (2013) Oncol. Lett. , vol.5 , pp. 722-728
    • Zhang, H.B.1    Lu, P.2    Guo, Q.Y.3
  • 14
    • 80051791387 scopus 로고    scopus 로고
    • Wogonin suppresses arrhythmias, inflammatory responses, and apoptosis induced by myocardial ischemia/reperfusion in rats
    • Y.M. Lee, P.Y. Cheng, and S.Y. Chen Wogonin suppresses arrhythmias, inflammatory responses, and apoptosis induced by myocardial ischemia/reperfusion in rats J. Cardiovasc. Pharmacol. 58 2011 133 142
    • (2011) J. Cardiovasc. Pharmacol. , vol.58 , pp. 133-142
    • Lee, Y.M.1    Cheng, P.Y.2    Chen, S.Y.3
  • 15
    • 79960985400 scopus 로고    scopus 로고
    • Synergistic activity of baicalein with ribavirin against influenza A (H1N1) virus infections in cell culture and in mice
    • L. Chen, J. Dou, and Z. Su Synergistic activity of baicalein with ribavirin against influenza A (H1N1) virus infections in cell culture and in mice Antivir. Res. 91 2011 314 320
    • (2011) Antivir. Res. , vol.91 , pp. 314-320
    • Chen, L.1    Dou, J.2    Su, Z.3
  • 16
    • 84869441936 scopus 로고    scopus 로고
    • In vitro antifungal activity of the flavonoid baicalein against Candida species
    • R. Serpa, E.J. França, and L. Furlaneto-Maia In vitro antifungal activity of the flavonoid baicalein against Candida species J. Med. Microbiol. 61 Pt 12 2012 1704 1708
    • (2012) J. Med. Microbiol. , vol.61 , Issue.PART 12 , pp. 1704-1708
    • Serpa, R.1    França, E.J.2    Furlaneto-Maia, L.3
  • 17
    • 84864329642 scopus 로고    scopus 로고
    • The anticonvulsant and neuroprotective effects of baicalin on pilocarpine-induced epileptic model in rats
    • Y.F. Liu, F. Gao, and X.W. Li The anticonvulsant and neuroprotective effects of baicalin on pilocarpine-induced epileptic model in rats Neurochem. Res. 37 2012 1670 1680
    • (2012) Neurochem. Res. , vol.37 , pp. 1670-1680
    • Liu, Y.F.1    Gao, F.2    Li, X.W.3
  • 18
    • 84876331167 scopus 로고    scopus 로고
    • Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest
    • L. Zhu, L. Zhao, and H. Wang Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest Toxicol. Lett. 219 2013 107 115
    • (2013) Toxicol. Lett. , vol.219 , pp. 107-115
    • Zhu, L.1    Zhao, L.2    Wang, H.3
  • 19
    • 84861130292 scopus 로고    scopus 로고
    • Down-regulation of the PI3K/Akt signaling pathway and induction of apoptosis in CA46 Burkitt lymphoma cells by baicalin
    • Y. Huang, J. Hu, and J. Zheng Down-regulation of the PI3K/Akt signaling pathway and induction of apoptosis in CA46 Burkitt lymphoma cells by baicalin J. Exp. Clin. Cancer Res. 20 2012 31 48
    • (2012) J. Exp. Clin. Cancer Res. , vol.20 , pp. 31-48
    • Huang, Y.1    Hu, J.2    Zheng, J.3
  • 20
    • 80054952939 scopus 로고    scopus 로고
    • Wogonin, an active ingredient of Chinese herb medicine Scutellaria baicalensis, inhibits the mobility and invasion of human gallbladder carcinoma GBC-SD cells by inducing the expression of maspin
    • P. Dong, Y. Zhang, and J. Gu Wogonin, an active ingredient of Chinese herb medicine Scutellaria baicalensis, inhibits the mobility and invasion of human gallbladder carcinoma GBC-SD cells by inducing the expression of maspin J. Ethnopharmacol. 137 2011 1373 1380
    • (2011) J. Ethnopharmacol. , vol.137 , pp. 1373-1380
    • Dong, P.1    Zhang, Y.2    Gu, J.3
  • 22
    • 80054884803 scopus 로고    scopus 로고
    • Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones
    • C. Li, G. Lin, and Z. Zuo Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones Biopharm. Drug Dispos. 32 2011 427 445
    • (2011) Biopharm. Drug Dispos. , vol.32 , pp. 427-445
    • Li, C.1    Lin, G.2    Zuo, Z.3
  • 23
    • 70649114483 scopus 로고    scopus 로고
    • Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells
    • C.Z. Wang, X.L. Li, and Q.F. Wang Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells Phytomedicine 17 2010 63 68
    • (2010) Phytomedicine , vol.17 , pp. 63-68
    • Wang, C.Z.1    Li, X.L.2    Wang, Q.F.3
  • 24
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • S. Lamouille, J. Xu, and R. Derynck Molecular mechanisms of epithelial-mesenchymal transition Nat. Rev. Mol. Cell. Biol. 15 2014 178 196
    • (2014) Nat. Rev. Mol. Cell. Biol. , vol.15 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 25
    • 65549123466 scopus 로고    scopus 로고
    • Molecular mechanisms controlling E-cadherin expression in breast cancer
    • S. Baranwal, and S.K. Alahari Molecular mechanisms controlling E-cadherin expression in breast cancer Biochem. Biophys. Res. Commun. 384 2009 6 11
    • (2009) Biochem. Biophys. Res. Commun. , vol.384 , pp. 6-11
    • Baranwal, S.1    Alahari, S.K.2
  • 26
    • 66149171486 scopus 로고    scopus 로고
    • Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy
    • Q. Zhang, B.T. Helfand, and T.L. Jang Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy Clin. Cancer Res. 15 2009 3557 3567
    • (2009) Clin. Cancer Res. , vol.15 , pp. 3557-3567
    • Zhang, Q.1    Helfand, B.T.2    Jang, T.L.3
  • 27
    • 77954030498 scopus 로고    scopus 로고
    • NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells
    • H.J. Maier, U. Schmidt-Strassburger, and M.A. Huber NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells Cancer Lett. 295 2010 214 228
    • (2010) Cancer Lett. , vol.295 , pp. 214-228
    • Maier, H.J.1    Schmidt-Strassburger, U.2    Huber, M.A.3
  • 28
    • 84861455323 scopus 로고    scopus 로고
    • PPARγ activation by baicalin suppresses NF-κB-mediated inflammation in aged rat kidney
    • H.A. Lim, E.K. Lee, and J.M. Kim PPARγ activation by baicalin suppresses NF-κB-mediated inflammation in aged rat kidney Biogerontology 13 2012 133 145
    • (2012) Biogerontology , vol.13 , pp. 133-145
    • Lim, H.A.1    Lee, E.K.2    Kim, J.M.3
  • 29
    • 79952667689 scopus 로고    scopus 로고
    • Modulation of NF-κB and FOXOs by baicalein attenuates the radiation-induced inflammatory process in mouse kidney
    • E.K. Lee, J.M. Kim, and J. Choi Modulation of NF-κB and FOXOs by baicalein attenuates the radiation-induced inflammatory process in mouse kidney Free Radic. Res. 45 2011 507 517
    • (2011) Free Radic. Res. , vol.45 , pp. 507-517
    • Lee, E.K.1    Kim, J.M.2    Choi, J.3
  • 30
    • 5444230567 scopus 로고    scopus 로고
    • Transcriptional regulation of cadherins during development and carcinogenesis
    • H. Peinado, F. Portillo, and A. Cano Transcriptional regulation of cadherins during development and carcinogenesis Int. J. Dev. Biol. 48 2004 365 375
    • (2004) Int. J. Dev. Biol. , vol.48 , pp. 365-375
    • Peinado, H.1    Portillo, F.2    Cano, A.3
  • 31
    • 45149092780 scopus 로고    scopus 로고
    • NF-kappaB and epithelial to mesenchymal transition of cancer
    • C. Min, S.F. Eddy, and D.H. Sherr NF-kappaB and epithelial to mesenchymal transition of cancer J. Cell. Biochem. 104 2008 733 744
    • (2008) J. Cell. Biochem. , vol.104 , pp. 733-744
    • Min, C.1    Eddy, S.F.2    Sherr, D.H.3
  • 32
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • S.A. Mani, W. Guo, and M.J. Liao The epithelial-mesenchymal transition generates cells with properties of stem cells Cell 133 2008 704 715
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.