Increased 4-hydroxynonenal protein adducts in male GSTA4–4/PPAR-α double knockout mice enhance injury during early stages of alcoholic liver disease

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 308, Issue 5, 2015, Pages G403-G415

  Ronis, Martin J J ^a,c   Mercer, Kelly E ^a,c   Gannon, Brenda ^a   Engi, Bridgette ^b   Zimniak, Piotr ^c   Shearn, Colin T ^d   Orlicky, David J ^d   Albano, Emanuele ^e   Badger, Thomas M ^a,c   Petersen, Dennis R ^d  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c U S DEPARTMENT OF AGRICULTURE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

^e UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

4 hydroxynonenal; Alcohol; Glutathione S transferase A4 4; Lipid peroxidation; Liver; Peroxisome proliferator activated receptor

Indexed keywords

4 HYDROXYNONENAL; ALANINE AMINOTRANSFERASE; ALCOHOL; ALPHA SMOOTH MUSCLE ACTIN; CD14 ANTIGEN; COLLAGEN TYPE 1; COLLAGENASE 3; CXCL2 CHEMOKINE; GELATINASE B; GLUTATHIONE TRANSFERASE A4; INTERLEUKIN 6; MALONALDEHYDE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SYNDECAN 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; 4-HYDROXY-2-NONENAL; ACTIN; ALDEHYDE; ALPHA-SMOOTH MUSCLE ACTIN, MOUSE; ANTIBODY; CXCL2 PROTEIN, MOUSE; CYTOKINE; GLUTATHIONE TRANSFERASE; GSTA4-4 PROTEIN, MOUSE; MATRIX METALLOPROTEINASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL LIVER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ARTICLE; CD3+ T LYMPHOCYTE; CELL ACTIVATION; CELL POPULATION; DIET; FIBROSIS; GENOTYPE; KNOCKOUT MOUSE; LIPID PEROXIDATION; LIVER INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEATOSIS; ANIMAL; BLOOD; GENE DELETION; GENETICS; IMMUNOLOGY; LIVER; METABOLISM; PATHOLOGY;

ACTINS; ALANINE TRANSAMINASE; ALDEHYDES; ANIMALS; ANTIBODIES; ANTIGENS, CD14; CHEMOKINE CXCL2; CYTOKINES; FIBROSIS; GENE DELETION; GLUTATHIONE TRANSFERASE; LIPID PEROXIDATION; LIVER; LIVER DISEASES, ALCOHOLIC; MALE; MATRIX METALLOPROTEINASES; MICE; PPAR ALPHA; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84924038374     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00154.2014     Document Type: Article

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