The course of CCl4 induced hepatotoxicity is altered in mGSTA4-4 null (-/-) mice

Toxicology

Volumn 218, Issue 1, 2006, Pages 58-66

  Dwivedi, Seema ^a   Sharma, Rajendra ^a   Sharma, Abha ^a   Zimniak, Piotr ^b   Ceci, Jeffrey D ^a   Awasthi, Yogesh C ^a   Boor, Paul J ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

Author keywords

Carbon tetrachloride; Glutathione S transferase; Hepatotoxicity; Lipid peroxidation

Indexed keywords

CARBON TETRACHLORIDE; FREE RADICAL; GLUTATHIONE TRANSFERASE; 4 HYDROXYNONENAL; 4-HYDROXY-2-NONENAL; ALDEHYDE; MGSTA4 4; MGSTA4-4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL SWELLING; CELL VACUOLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; ENZYME ACTIVITY; HISTOPATHOLOGY; LIVER NECROSIS; LIVER TOXICITY; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE; ANIMAL; BIOSYNTHESIS; DRUG EFFECT; ENZYMOLOGY; GENETICS; LIPID PEROXIDATION; LIVER; METABOLISM; MOUSE MUTANT; PATHOLOGY; SPLEEN; TESTIS; TOXIC HEPATITIS; WESTERN BLOTTING;

ANIMALIA;

ALDEHYDES; ANIMALS; BLOTTING, WESTERN; CARBON TETRACHLORIDE; GLUTATHIONE TRANSFERASE; HEPATITIS, TOXIC; LIPID PEROXIDATION; LIVER; MALE; MICE; MICE, KNOCKOUT; SPLEEN; TESTIS;

EID: 28844492098     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2005.10.012     Document Type: Article

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