Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibition by 4-hydroxynonenal leads to increased Akt activation in hepatocytes

Molecular Pharmacology

Volumn 79, Issue 6, 2011, Pages 941-952

  Shearn, Colin T ^a   Smathers, Rebecca L ^a   Stewart, Benjamin J ^c   Fritz, Kristofer S ^a   Galligan, James J ^b   Hail Jr , Numsen ^a   Petersen, Dennis R ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 HYDROXYNONENAL; OKADAIC ACID; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; LIVER CELL; MASS SPECTROMETRY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ALDEHYDES; ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; CELLS, CULTURED; DNA PRIMERS; ENZYME ACTIVATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEPATOCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, CONFOCAL; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS;

EID: 79956333653     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.069534     Document Type: Article

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