The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells

Journal of Clinical Investigation

Volumn 122, Issue 12, 2012, Pages 4698-4709

  Brüstle, Anne ^a   Brenner, Dirk ^a,b   Knobbe, Christiane B ^a,c   Lang, Philipp A ^a,c,d   Virtanen, Carl ^e   Hershenfield, Brian M ^a,d   Reardon, Colin ^a   Lacher, Sonja M ^a   Ruland, Jürgen ^b,f   Ohashi, Pamela S ^a,d   Mak, Tak W ^a,d  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY HEALTH NETWORK   (Canada)

^f INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 17; INTERLEUKIN 22; MALT1 PROTEIN; MESSENGER RNA; REGULATOR PROTEIN; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR GAMMA; TRANSCRIPTION FACTOR RELB; TUBULIN; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CELLULAR DISTRIBUTION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY T LYMPHOCYTE; SPLEEN; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TH2 CELL;

ANIMALS; CASPASES; CELL DIFFERENTIATION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERLEUKIN-17; INTERLEUKINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASM PROTEINS; NF-KAPPA B; PROTEOLYSIS; TH1 CELLS; TH17 CELLS; TRANSCRIPTION FACTOR RELB; TRANSCRIPTION FACTORS;

EID: 84870521827     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI63528     Document Type: Article

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