Ectodomain shedding of the Notch ligand Jagged1 is mediated by ADAM17, but is not a lipid-raft-associated event

Biochemical Journal

Volumn 432, Issue 2, 2010, Pages 283-294

  Parr Sturgess, Catherine A ^a   Rushton, David J ^a   Parkin, Edward T ^a  

^a LANCASTER UNIVERSITY   (United Kingdom)

Author keywords

A disintegrin and metalloproteinase 17 (ADAM17); Amyloid precursor protein; Glycosylphosphatidylinositol (GPI); Jagged1; Lipid raft; Notch

Indexed keywords

AMYLOID PRECURSOR PROTEINS; GLYCOSYLPHOSPHATIDYLINOSITOL; JAGGED1; LIPID RAFT; METALLOPROTEINASES; NOTCH;

CELL MEMBRANES; CYTOLOGY; ENZYME ACTIVITY; ESTERS; GLYCOPROTEINS; LIGANDS;

PROTEINS;

ADAM PROTEIN; ADAM10 ENDOPEPTIDASE; ADAM17 ENDOPEPTIDASE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; ILOMASTAT; JAGGED1; PHORBOL ESTER; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONTROLLED STUDY; LIPID RAFT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; PROTEIN VARIANT; WILD TYPE;

ADAM PROTEINS; ALKALINE PHOSPHATASE; BASE SEQUENCE; CALCIUM-BINDING PROTEINS; CELL MEMBRANE; CONSERVED SEQUENCE; CYTOSOL; EVOLUTION, MOLECULAR; HEK293 CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; PEPTIDE FRAGMENTS; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 78649583249     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20100321     Document Type: Article

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