Separation of achiral analytes using supercritical fluid chromatography with chiral stationary phases

TrAC - Trends in Analytical Chemistry

Volumn 67, Issue , 2015, Pages 74-81

  Regalado, Erik L ^a   Welch, Christopher J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Achiral separation; Chiral stationary phase; Chiral supercritical fluid chromatography; Closely related species; Complex mixture; Method development; Supercritical fluid chromatography; Ultra high performance liquid chromatography

Indexed keywords

ALKYLATION; COLUMN CHROMATOGRAPHY; EFFLUENT TREATMENT; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERS; LIQUID CHROMATOGRAPHY; LIQUIDS; MIXTURES; SEPARATION; STEREOCHEMISTRY; SUPERCRITICAL FLUIDS;

CHIRAL STATIONARY PHASE; CLOSELY-RELATED SPECIES; COMPLEX MIXTURE; METHOD DEVELOPMENT; SUPER CRITICAL FLUID CHROMATOGRAPHY; ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHIES;

CHROMATOGRAPHY;

DRUG METABOLITE; HALOGEN;

CHIRAL CHROMATOGRAPHY; CHIRAL STATIONARY PHASE; CONTROLLED STUDY; DEMETHYLATION; DIASTEREOISOMER; HYDROXYLATION; ISOMER; LIQUID CHROMATOGRAPHY; METHYLATION; PRIORITY JOURNAL; REVIEW; SUPERCRITICAL FLUID CHROMATOGRAPHY;

EID: 84923878603     PISSN: 01659936     EISSN: 18793142     Source Type: Journal    
DOI: 10.1016/j.trac.2015.01.004     Document Type: Review

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