Analysis of pharmaceutical impurities using multi-heartcutting 2D LC coupled with UV-charged aerosol MS detection

Journal of Separation Science

Volumn 36, Issue 18, 2013, Pages 2986-2992

  Zhang, Kelly ^a   Li, Yi ^a   Tsang, Midco ^a   Chetwyn, Nik P ^a  

^a GENENTECH INC   (United States)

Author keywords

2D LC; Charged aerosol detection; Hydrophilic interaction liquid chromatography; Hyphenation; Pharmaceutical analysis

Indexed keywords

2D LC; CHARGED AEROSOL DETECTION; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHIES; HYPHENATION; PHARMACEUTICAL ANALYSIS;

CHROMATOGRAPHY; DEGRADATION; DRUG PRODUCTS; IMPURITIES; SEPARATION;

AEROSOLS;

PHOSPHATE BUFFERED SALINE;

AEROSOL; ARTICLE; CHEMICAL STRUCTURE; CHROMATOPHORE; DRUG IMPURITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILIC INTERACTION CHROMATOGRAPHY; MULTI HEARTCUTTING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SEPARATION TECHNIQUE; STRUCTURE ANALYSIS; ULTRAVIOLET RADIATION;

2D LC; CHARGED AEROSOL DETECTION; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY; HYPHENATION; PHARMACEUTICAL ANALYSIS;

AEROSOLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS; ULTRAVIOLET RAYS;

EID: 84884269747     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201300493     Document Type: Article

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