Chromatographic resolution of closely related species in pharmaceutical chemistry: Dehalogenation impurities and mixtures of halogen isomers

Analytical Chemistry

Volumn 86, Issue 1, 2014, Pages 805-813

  Regalado, Erik L ^a   Zhuang, Ping ^a   Chen, Yadan ^a   Makarov, Alexey A ^a   Schafer, Wes A ^a   McGachy, Neil ^a   Welch, Christopher J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHIC METHODS; CHROMATOGRAPHIC RESOLUTIONS; CHROMATOGRAPHIC SEPARATIONS; PHARMACEUTICAL CHEMISTRY; PHARMACEUTICAL INDUSTRY; SODIUM PERCHLORATE; SUPER CRITICAL FLUID CHROMATOGRAPHY; ULTRA HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (UHPLC);

BIOACTIVITY; CHROMATOGRAPHIC ANALYSIS; GAS CHROMATOGRAPHY; GOLD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMPURITIES; MIXTURES; MOLECULES; STEREOCHEMISTRY; SURVEYS; SYNTHESIS (CHEMICAL);

ISOMERS;

HALOGEN;

ARTICLE; CHEMISTRY; DRUG CONTAMINATION; HALOGENATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERISM; MEDICINAL CHEMISTRY; METHODOLOGY;

CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; HALOGENATION; HALOGENS; ISOMERISM;

EID: 84891769475     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac403376h     Document Type: Article

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