Comparison of chromatographic techniques for diastereomer separation of a diverse set of drug-like compounds

Journal of Chromatography A

Volumn 1272, Issue , 2013, Pages 150-154

  Ebinger, Katalin ^a   Weller, Harold N ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Achiral columns; Ammonium cation additive; Diastereomers; Isomer separation; Selectivity; SFC (supercritical fluid chromatography)

Indexed keywords

AMMONIUM CATIONS; CHROMATOGRAPHIC TECHNIQUES; DIASTEREOMERIC; DIASTEREOMERS; ISOCRATIC; ISOMER SEPARATION; RELATIVE UTILITY; REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SAMPLE SETS; SUPER CRITICAL FLUID CHROMATOGRAPHY;

AMMONIUM COMPOUNDS; CATALYST SELECTIVITY; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

SEPARATION;

ARTICLE; COMPARATIVE EFFECTIVENESS; CROSS LINKING; DIASTEREOISOMER; FLOW RATE; HYDROGEN BOND; INTERMETHOD COMPARISON; MOLECULAR WEIGHT; PHASE SEPARATION; PRIORITY JOURNAL; PROCESS DEVELOPMENT; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SUPERCRITICAL FLUID CHROMATOGRAPHY;

CHROMATOGRAPHY; HYDROGEN BONDING; MOLECULAR WEIGHT; PHARMACEUTICAL PREPARATIONS; STEREOISOMERISM;

EID: 84871920517     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.11.065     Document Type: Article

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