메뉴 건너뛰기




Volumn 95, Issue 5, 2015, Pages 804-818

Targets of the Sex Inducer homeodomain proteins are required for fungal development and virulence in Cryptococcus neoformans

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN; HOMEODOMAIN PROTEIN SXI1ALPHA; HOMEODOMAIN PROTEIN SXI2ALPHA; UNCLASSIFIED DRUG; TRANSCRIPTION FACTOR;

EID: 84923876035     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12898     Document Type: Article
Times cited : (15)

References (64)
  • 1
    • 0030668723 scopus 로고    scopus 로고
    • Cryptococcus neoformans mating and virulence are regulated by the G-protein αsubunit GPA1 and cAMP
    • Alspaugh, J.A., Perfect, J.R., and Heitman, J. (1997) Cryptococcus neoformans mating and virulence are regulated by the G-protein αsubunit GPA1 and cAMP. Genes & Dev 11: 3206-3217.
    • (1997) Genes & Dev , vol.11 , pp. 3206-3217
    • Alspaugh, J.A.1    Perfect, J.R.2    Heitman, J.3
  • 2
    • 0034052527 scopus 로고    scopus 로고
    • RAS1 regulates filamentation, mating and growth at high temperature of Cryptococcus neoformans
    • Alspaugh, J.A., Cavallo, L.M., Perfect, J.R., and Heitman, J. (2000) RAS1 regulates filamentation, mating and growth at high temperature of Cryptococcus neoformans. Mol Microbiol 36: 352-365.
    • (2000) Mol Microbiol , vol.36 , pp. 352-365
    • Alspaugh, J.A.1    Cavallo, L.M.2    Perfect, J.R.3    Heitman, J.4
  • 3
    • 0028685490 scopus 로고
    • Fitting a mixture model by expectation maximization to discover motifs in biopolymers
    • Bailey, T.L., and Elkan, C. (1994) Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc Int Conf Intell Syst Mol Biol 2: 28-36.
    • (1994) Proc Int Conf Intell Syst Mol Biol , vol.2 , pp. 28-36
    • Bailey, T.L.1    Elkan, C.2
  • 4
    • 0031877016 scopus 로고    scopus 로고
    • Combining evidence using p-values: application to sequence homology searches
    • Bailey, T.L., and Gribskov, M. (1998) Combining evidence using p-values: application to sequence homology searches. Bioinformatics 14: 48-54.
    • (1998) Bioinformatics , vol.14 , pp. 48-54
    • Bailey, T.L.1    Gribskov, M.2
  • 5
    • 0031037986 scopus 로고    scopus 로고
    • Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression
    • Bradford, A.P., Wasylyk, C., Wasylyk, B., and Gutierrez-Hartmann, A. (1997) Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression. Mol Cell Biol 17: 1065-1074.
    • (1997) Mol Cell Biol , vol.17 , pp. 1065-1074
    • Bradford, A.P.1    Wasylyk, C.2    Wasylyk, B.3    Gutierrez-Hartmann, A.4
  • 6
    • 0028838826 scopus 로고
    • Determining the requirements for cooperative DNA binding by Swi5p and Pho2p (Grf10p/Bas2p) at the HO promoter
    • Brazas, R.M., Bhoite, L.T., Murphy, M.D., Yu, Y., Chen, Y., Neklason, D.W., and Stillman, D.J. (1995) Determining the requirements for cooperative DNA binding by Swi5p and Pho2p (Grf10p/Bas2p) at the HO promoter. J Biol Chem 270: 29151-29161.
    • (1995) J Biol Chem , vol.270 , pp. 29151-29161
    • Brazas, R.M.1    Bhoite, L.T.2    Murphy, M.D.3    Yu, Y.4    Chen, Y.5    Neklason, D.W.6    Stillman, D.J.7
  • 7
    • 0000386558 scopus 로고    scopus 로고
    • Analysis of RNA by northern and slot blot hybridization
    • Brown, T., and Mackey, K. (1997) Analysis of RNA by northern and slot blot hybridization. Curr Protoc Mol Biol 37: 4.9.1-4.9.16.
    • (1997) Curr Protoc Mol Biol , vol.37 , pp. 491-4916
    • Brown, T.1    Mackey, K.2
  • 8
    • 77949509793 scopus 로고    scopus 로고
    • Specificity landscapes of DNA binding molecules elucidate biological function
    • Carlson, C.D., Warren, C.L., Hauschild, K.E., Ozers, M.S., Qadir, N., Bhimsaria, D., etal. (2010) Specificity landscapes of DNA binding molecules elucidate biological function. PNAS 107: 4544-4549.
    • (2010) PNAS , vol.107 , pp. 4544-4549
    • Carlson, C.D.1    Warren, C.L.2    Hauschild, K.E.3    Ozers, M.S.4    Qadir, N.5    Bhimsaria, D.6
  • 9
    • 0035853109 scopus 로고    scopus 로고
    • The second STE12 homologue of Cryptococcus neoformans is MATa-specific and plays an important role in virulence
    • Chang, Y.C., Penoyer, L.A., and Kwon-Chung, K.J. (2001) The second STE12 homologue of Cryptococcus neoformans is MATa-specific and plays an important role in virulence. Proc Natl Acad Sci USA 98: 3258-3263.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3258-3263
    • Chang, Y.C.1    Penoyer, L.A.2    Kwon-Chung, K.J.3
  • 10
    • 0042825487 scopus 로고    scopus 로고
    • Importance of a developmentally regulated pheromone receptor of Cryptococcus neoformans for virulence
    • Chang, Y.C., Miller, G.F., and Kwon-Chung, K.J. (2003) Importance of a developmentally regulated pheromone receptor of Cryptococcus neoformans for virulence. Infect Immun 71: 4953-4960.
    • (2003) Infect Immun , vol.71 , pp. 4953-4960
    • Chang, Y.C.1    Miller, G.F.2    Kwon-Chung, K.J.3
  • 12
    • 40649108877 scopus 로고    scopus 로고
    • Sexual Development in Cryptococcus neoformans requires CLP1, a target of the homeodomain transcription factors Sxi1α and Sxi2a
    • Ekena, J.L., Stanton, B.C., Schiebe-Owens, J.A., and Hull, C.M. (2008) Sexual Development in Cryptococcus neoformans requires CLP1, a target of the homeodomain transcription factors Sxi1α and Sxi2a. Eukaryot Cell 7: 49-57.
    • (2008) Eukaryot Cell , vol.7 , pp. 49-57
    • Ekena, J.L.1    Stanton, B.C.2    Schiebe-Owens, J.A.3    Hull, C.M.4
  • 13
    • 79956356167 scopus 로고    scopus 로고
    • Nutrient acquisition by pathogenic fungi: nutrient availability, pathway regulation, and differences in substrate utilization
    • Fleck, C.B., Schöbel, F., and Brock, M. (2011) Nutrient acquisition by pathogenic fungi: nutrient availability, pathway regulation, and differences in substrate utilization. Int J Med Microbiol 301: 400-407.
    • (2011) Int J Med Microbiol , vol.301 , pp. 400-407
    • Fleck, C.B.1    Schöbel, F.2    Brock, M.3
  • 15
    • 0027753923 scopus 로고
    • Exploring the homeobox
    • Gehring, W.J. (1993) Exploring the homeobox. Gene 135: 215-221.
    • (1993) Gene , vol.135 , pp. 215-221
    • Gehring, W.J.1
  • 16
    • 67651205627 scopus 로고    scopus 로고
    • Elucidating the pathogenesis of spores from the human fungal pathogen Cryptococcus neoformans
    • Giles, S.S., Dagenais, T.R.T., Botts, M.R., Keller, N.P., and Hull, C.M. (2009) Elucidating the pathogenesis of spores from the human fungal pathogen Cryptococcus neoformans. Infect Immun 77: 3491-3500.
    • (2009) Infect Immun , vol.77 , pp. 3491-3500
    • Giles, S.S.1    Dagenais, T.R.T.2    Botts, M.R.3    Keller, N.P.4    Hull, C.M.5
  • 17
    • 0027527069 scopus 로고
    • Yeast a1 and α2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein
    • Goutte, C., and Johnson, A.D. (1993) Yeast a1 and α2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233: 359-371.
    • (1993) J Mol Biol , vol.233 , pp. 359-371
    • Goutte, C.1    Johnson, A.D.2
  • 18
    • 0028325785 scopus 로고
    • Recognition of a DNA operator by a dimer composed of two different homeodomain proteins
    • Goutte, C., and Johnson, A.D. (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13: 1434-1442.
    • (1994) EMBO J , vol.13 , pp. 1434-1442
    • Goutte, C.1    Johnson, A.D.2
  • 19
    • 0020739930 scopus 로고
    • Heme regulates transcription of the CYC1 gene of S.cerevisiae via an upstream activation site
    • Guarente, L., and Mason, T. (1983) Heme regulates transcription of the CYC1 gene of S.cerevisiae via an upstream activation site. Cell 32: 1279-1286.
    • (1983) Cell , vol.32 , pp. 1279-1286
    • Guarente, L.1    Mason, T.2
  • 20
    • 77958112730 scopus 로고    scopus 로고
    • The transcription factor Rbf1 is the master regulator for b-mating type controlled pathogenic development in Ustilago maydis
    • Heimel, K., Scherer, M., Vranes, M., Wahl, R., Pothiratana, C., Schuler, D., etal. (2010) The transcription factor Rbf1 is the master regulator for b-mating type controlled pathogenic development in Ustilago maydis. PLoS Pathog 6: e1001035.
    • (2010) PLoS Pathog , vol.6 , pp. e1001035
    • Heimel, K.1    Scherer, M.2    Vranes, M.3    Wahl, R.4    Pothiratana, C.5    Schuler, D.6
  • 21
    • 65649135441 scopus 로고    scopus 로고
    • A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans
    • Hsueh, Y.-P., Xue, C., and Heitman, J. (2009) A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans. EMBO J 28: 1220-1233.
    • (2009) EMBO J , vol.28 , pp. 1220-1233
    • Hsueh, Y.-P.1    Xue, C.2    Heitman, J.3
  • 22
    • 50049125079 scopus 로고    scopus 로고
    • Metabolic adaptation in Cryptococcus neoformans during early murine pulmonary infection
    • Hu, G., Cheng, P.-Y., Sham, A., Perfect, J.R., and Kronstad, J.W. (2008) Metabolic adaptation in Cryptococcus neoformans during early murine pulmonary infection. Mol Microbiol 69: 1456-1475.
    • (2008) Mol Microbiol , vol.69 , pp. 1456-1475
    • Hu, G.1    Cheng, P.-Y.2    Sham, A.3    Perfect, J.R.4    Kronstad, J.W.5
  • 23
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang, D.W., Sherman, B.T., and Lempicki, R.A. (2008) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
    • (2008) Nat Protoc , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 24
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
    • Huang, D.W., Sherman, B.T., and Lempicki, R.A. (2009) Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37: 1-13.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 25
    • 0036894726 scopus 로고    scopus 로고
    • Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1α
    • Hull, C.M., Davidson, R.C., and Heitman, J. (2002) Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1α. Genes & Dev 16: 3046-3060.
    • (2002) Genes & Dev , vol.16 , pp. 3046-3060
    • Hull, C.M.1    Davidson, R.C.2    Heitman, J.3
  • 26
    • 2542587112 scopus 로고    scopus 로고
    • The alpha-specific cell identity factor Sxi1α is not required for virulence of Cryptococcus neoformans
    • Hull, C.M., Cox, G.M., and Heitman, J. (2004) The alpha-specific cell identity factor Sxi1α is not required for virulence of Cryptococcus neoformans. Infect Immun 72: 3643-3645.
    • (2004) Infect Immun , vol.72 , pp. 3643-3645
    • Hull, C.M.1    Cox, G.M.2    Heitman, J.3
  • 27
    • 15244354604 scopus 로고    scopus 로고
    • Sex-specific homeodomain proteins Sxi1α and Sxi2a coordinately regulate sexual development in Cryptococcus neoformans
    • Hull, C.M., Boily, M.-J., and Heitman, J. (2005) Sex-specific homeodomain proteins Sxi1α and Sxi2a coordinately regulate sexual development in Cryptococcus neoformans. Eukaryot Cell 4: 526-535.
    • (2005) Eukaryot Cell , vol.4 , pp. 526-535
    • Hull, C.M.1    Boily, M.-J.2    Heitman, J.3
  • 28
    • 0029154633 scopus 로고
    • Molecular mechanisms of cell-type determination in budding yeast
    • Johnson, A.D. (1995) Molecular mechanisms of cell-type determination in budding yeast. Curr Opin Genet Dev 5: 552-558.
    • (1995) Curr Opin Genet Dev , vol.5 , pp. 552-558
    • Johnson, A.D.1
  • 29
    • 77649290327 scopus 로고    scopus 로고
    • The Stress-Activated Signaling (SAS) pathways of a human fungal pathogen, Cryptococcus neoformans
    • Jung, K.-W., and Bahn, Y.-S. (2009) The Stress-Activated Signaling (SAS) pathways of a human fungal pathogen, Cryptococcus neoformans. Mycobiology 37: 161-170.
    • (2009) Mycobiology , vol.37 , pp. 161-170
    • Jung, K.-W.1    Bahn, Y.-S.2
  • 30
    • 0038460048 scopus 로고    scopus 로고
    • The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function
    • Kraus, P.R., Fox, D.S., Cox, G.M., and Heitman, J. (2003) The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function. Mol Microbiol 48: 1377-1387.
    • (2003) Mol Microbiol , vol.48 , pp. 1377-1387
    • Kraus, P.R.1    Fox, D.S.2    Cox, G.M.3    Heitman, J.4
  • 31
    • 84863012334 scopus 로고    scopus 로고
    • Adaptation of Cryptococcus neoformans to mammalian hosts: integrated regulation of metabolism and virulence
    • Kronstad, J., Saikia, S., Nielson, E.D., Kretschmer, M., Jung, W., Hu, G., etal. (2012) Adaptation of Cryptococcus neoformans to mammalian hosts: integrated regulation of metabolism and virulence. Eukaryot Cell 11: 109-118.
    • (2012) Eukaryot Cell , vol.11 , pp. 109-118
    • Kronstad, J.1    Saikia, S.2    Nielson, E.D.3    Kretschmer, M.4    Jung, W.5    Hu, G.6
  • 32
    • 84862532332 scopus 로고    scopus 로고
    • Analysis of Cryptococcus neoformans sexual development reveals rewiring of the pheromone-response network by a change in transcription factor identity
    • Kruzel, E.K., Giles, S.S., and Hull, C.M. (2012) Analysis of Cryptococcus neoformans sexual development reveals rewiring of the pheromone-response network by a change in transcription factor identity. Genetics 191: 435-449.
    • (2012) Genetics , vol.191 , pp. 435-449
    • Kruzel, E.K.1    Giles, S.S.2    Hull, C.M.3
  • 33
    • 0027968435 scopus 로고
    • A chimeric homeodomain protein causes self-compatibility and constitutive sexual development in the mushroom Coprinus cinereus
    • Kües, U., Göttgens, B., Stratmann, R., Richardson, W.V., O'Shea, S.F., and Casselton, L.A. (1994) A chimeric homeodomain protein causes self-compatibility and constitutive sexual development in the mushroom Coprinus cinereus. EMBO J 13: 4054-4059.
    • (1994) EMBO J , vol.13 , pp. 4054-4059
    • Kües, U.1    Göttgens, B.2    Stratmann, R.3    Richardson, W.V.4    O'Shea, S.F.5    Casselton, L.A.6
  • 34
    • 0026334016 scopus 로고
    • Genetic association of mating types and virulence in Cryptococcus neoformans
    • Kwon-Chung, K.J., Edman, J.C., and Wickes, B.L. (1992) Genetic association of mating types and virulence in Cryptococcus neoformans. Infect Immun 60: 602-605.
    • (1992) Infect Immun , vol.60 , pp. 602-605
    • Kwon-Chung, K.J.1    Edman, J.C.2    Wickes, B.L.3
  • 35
    • 0028828745 scopus 로고
    • Crystal structure of the MATa1/MATα2 homeodomain heterodimer bound to DNA
    • Li, T., Stark, M.R., Johnson, A.D., and Wolberger, C. (1995) Crystal structure of the MATa1/MATα2 homeodomain heterodimer bound to DNA. Science 270: 262-269.
    • (1995) Science , vol.270 , pp. 262-269
    • Li, T.1    Stark, M.R.2    Johnson, A.D.3    Wolberger, C.4
  • 36
    • 17844369955 scopus 로고    scopus 로고
    • Sexual reproduction between partners of the same mating type in Cryptococcus neoformans
    • Lin, X., Hull, C.M., and Heitman, J. (2005) Sexual reproduction between partners of the same mating type in Cryptococcus neoformans. Nature 434: 1017-1021.
    • (2005) Nature , vol.434 , pp. 1017-1021
    • Lin, X.1    Hull, C.M.2    Heitman, J.3
  • 37
    • 33751367691 scopus 로고    scopus 로고
    • Virulence attributes and hyphal growth of C.neoformans are quantitative traits and the MATα allele enhances filamentation
    • Lin, X., Huang, J.C., Mitchell, T.G., and Heitman, J. (2006) Virulence attributes and hyphal growth of C.neoformans are quantitative traits and the MATα allele enhances filamentation. PLoS Genet 2: e187.
    • (2006) PLoS Genet , vol.2 , pp. e187
    • Lin, X.1    Huang, J.C.2    Mitchell, T.G.3    Heitman, J.4
  • 38
    • 77953192777 scopus 로고    scopus 로고
    • Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite- and same-sex mating in Cryptococcus neoformans
    • Lin, X., Jackson, J.C., Feretzaki, M., Xue, C., and Heitman, J. (2010) Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite- and same-sex mating in Cryptococcus neoformans. PLoS Genet 6: e1000953.
    • (2010) PLoS Genet , vol.6 , pp. e1000953
    • Lin, X.1    Jackson, J.C.2    Feretzaki, M.3    Xue, C.4    Heitman, J.5
  • 39
    • 0347064089 scopus 로고    scopus 로고
    • Evidence of sexual recombination among Cryptococcus neoformans serotype a isolates in Sub-Saharan Africa
    • Litvintseva, A.P., Marra, R.E., Nielsen, K., Heitman, J., Vilgalys, R., and Mitchell, T.G. (2003) Evidence of sexual recombination among Cryptococcus neoformans serotype a isolates in Sub-Saharan Africa. Eukaryot Cell 2: 1162-1168.
    • (2003) Eukaryot Cell , vol.2 , pp. 1162-1168
    • Litvintseva, A.P.1    Marra, R.E.2    Nielsen, K.3    Heitman, J.4    Vilgalys, R.5    Mitchell, T.G.6
  • 40
    • 79960277492 scopus 로고    scopus 로고
    • Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument
    • Nutiu, R., Friedman, R.C., Luo, S., Khrebtukova, I., Silva, D., Li, R., etal. (2011) Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument. Nat Biotechnol 29: 659-664.
    • (2011) Nat Biotechnol , vol.29 , pp. 659-664
    • Nutiu, R.1    Friedman, R.C.2    Luo, S.3    Khrebtukova, I.4    Silva, D.5    Li, R.6
  • 41
    • 20044375362 scopus 로고    scopus 로고
    • The DEAD-box RNA helicase Vad1 regulates multiple virulence-associated genes in Cryptococcus neoformans
    • Panepinto, J., Liu, L., Ramos, J., Zhu, X., Valyi-Nagy, T., Eksi, S., etal. (2005) The DEAD-box RNA helicase Vad1 regulates multiple virulence-associated genes in Cryptococcus neoformans. J Clin Invest 115: 632-641.
    • (2005) J Clin Invest , vol.115 , pp. 632-641
    • Panepinto, J.1    Liu, L.2    Ramos, J.3    Zhu, X.4    Valyi-Nagy, T.5    Eksi, S.6
  • 42
    • 62349130224 scopus 로고    scopus 로고
    • Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS
    • Park, B.J., Wannemuehler, K.A., Marston, B.J., Govender, N., Pappas, P.G., and Chiller, T.M. (2009) Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. AIDS 23: 525-530.
    • (2009) AIDS , vol.23 , pp. 525-530
    • Park, B.J.1    Wannemuehler, K.A.2    Marston, B.J.3    Govender, N.4    Pappas, P.G.5    Chiller, T.M.6
  • 43
    • 78049407256 scopus 로고    scopus 로고
    • Mating pheromone in Cryptococcus neoformans is regulated by a transcriptional/degradative 'futile' cycle
    • Park, Y.-D., Panepinto, J., Shin, S., Larsen, P., Giles, S., and Williamson, P.R. (2010) Mating pheromone in Cryptococcus neoformans is regulated by a transcriptional/degradative 'futile' cycle. J Biol Chem 285: 34746-34756.
    • (2010) J Biol Chem , vol.285 , pp. 34746-34756
    • Park, Y.-D.1    Panepinto, J.2    Shin, S.3    Larsen, P.4    Giles, S.5    Williamson, P.R.6
  • 44
    • 55549103719 scopus 로고    scopus 로고
    • E2F in vivo binding specificity: comparison of consensus versus nonconsensus binding sites
    • Rabinovich, A., Jin, V.X., Rabinovich, R., Xu, X., and Farnham, P.J. (2008) E2F in vivo binding specificity: comparison of consensus versus nonconsensus binding sites. Genome Res 18: 1763-1777.
    • (2008) Genome Res , vol.18 , pp. 1763-1777
    • Rabinovich, A.1    Jin, V.X.2    Rabinovich, R.3    Xu, X.4    Farnham, P.J.5
  • 46
  • 47
    • 45849102001 scopus 로고    scopus 로고
    • A gene regulatory network orchestrates neural crest formation
    • Sauka-Spengler, T., and Bronner-Fraser, M. (2008) A gene regulatory network orchestrates neural crest formation. Nat Rev Mol Cell Biol 9: 557-568.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 557-568
    • Sauka-Spengler, T.1    Bronner-Fraser, M.2
  • 48
    • 33749240364 scopus 로고    scopus 로고
    • The Clp1 protein is required for clamp formation and pathogenic development of Ustilago maydis
    • Scherer, M.M., Heimel, K.K., Starke, V.V., and Kämper, J.J. (2006) The Clp1 protein is required for clamp formation and pathogenic development of Ustilago maydis. Plant Cell 18: 2388-2401.
    • (2006) Plant Cell , vol.18 , pp. 2388-2401
    • Scherer, M.M.1    Heimel, K.K.2    Starke, V.V.3    Kämper, J.J.4
  • 49
    • 19344375742 scopus 로고    scopus 로고
    • Transcriptional control in the segmentation gene network of drosophila
    • Schroeder, M.D., Pearce, M., Fak, J., Fan, H., Unnerstall, U., Emberly, E., etal. (2004) Transcriptional control in the segmentation gene network of drosophila. PLoS Biol 2: e271.
    • (2004) PLoS Biol , vol.2 , pp. e271
    • Schroeder, M.D.1    Pearce, M.2    Fak, J.3    Fan, H.4    Unnerstall, U.5    Emberly, E.6
  • 50
    • 0025034813 scopus 로고
    • The b alleles of U.maydis, whose combinations program pathogenic development, code for polypeptides containing a homeodomain-related motif
    • Schulz, B., Banuett, F., Dahl, M., Schlesinger, R., Schäfer, W., Martin, T., etal. (1990) The b alleles of U.maydis, whose combinations program pathogenic development, code for polypeptides containing a homeodomain-related motif. Cell 60: 295-306.
    • (1990) Cell , vol.60 , pp. 295-306
    • Schulz, B.1    Banuett, F.2    Dahl, M.3    Schlesinger, R.4    Schäfer, W.5    Martin, T.6
  • 51
    • 0346659955 scopus 로고
    • Identification of the DNA sequences controlling the expression of the MATα locus of yeast
    • Siliciano, P.G., and Tatchell, K. (1986) Identification of the DNA sequences controlling the expression of the MATα locus of yeast. Proc Natl Acad Sci USA 83: 2320-2324.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2320-2324
    • Siliciano, P.G.1    Tatchell, K.2
  • 52
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Smyth, G.K. (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3: Article 3.
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • Smyth, G.K.1
  • 53
    • 0242333835 scopus 로고    scopus 로고
    • Normalization of cDNA microarray data
    • Smyth, G.K., and Speed, T. (2003) Normalization of cDNA microarray data. Methods 31: 265-273.
    • (2003) Methods , vol.31 , pp. 265-273
    • Smyth, G.K.1    Speed, T.2
  • 54
    • 0032568586 scopus 로고    scopus 로고
    • A role for heterodimerization in nuclear localization of a homeodomain protein
    • Spit, A., Hyland, R.H., Mellor, E.J., and Casselton, L.A. (1998) A role for heterodimerization in nuclear localization of a homeodomain protein. Proc Natl Acad Sci USA 95: 6228-6233.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6228-6233
    • Spit, A.1    Hyland, R.H.2    Mellor, E.J.3    Casselton, L.A.4
  • 55
    • 66949111397 scopus 로고    scopus 로고
    • Cognate Site Identifier analysis reveals novel binding properties of the Sex Inducer homeodomain proteins of Cryptococcus neoformans
    • Stanton, B.C., Giles, S.S., Kruzel, E.K., Warren, C.L., Ansari, A.Z., and Hull, C.M. (2009) Cognate Site Identifier analysis reveals novel binding properties of the Sex Inducer homeodomain proteins of Cryptococcus neoformans. Mol Microbiol 72: 1334-1347.
    • (2009) Mol Microbiol , vol.72 , pp. 1334-1347
    • Stanton, B.C.1    Giles, S.S.2    Kruzel, E.K.3    Warren, C.L.4    Ansari, A.Z.5    Hull, C.M.6
  • 56
    • 0028021493 scopus 로고
    • Interaction between two homeodomain proteins is specified by a short C-terminal tail
    • Stark, M.R., and Johnson, A.D. (1994) Interaction between two homeodomain proteins is specified by a short C-terminal tail. Nature 371: 429-432.
    • (1994) Nature , vol.371 , pp. 429-432
    • Stark, M.R.1    Johnson, A.D.2
  • 57
    • 79957449903 scopus 로고    scopus 로고
    • Chapter 1 - sequence-specificity and energy landscapes of DNA-binding molecules
    • Tietjen, J.R., Donato, L.J., Bhimisaria, D., and Ansari, A.Z. (2011) Chapter 1 - sequence-specificity and energy landscapes of DNA-binding molecules. Methods Enzymol 497: 3-30.
    • (2011) Methods Enzymol , vol.497 , pp. 3-30
    • Tietjen, J.R.1    Donato, L.J.2    Bhimisaria, D.3    Ansari, A.Z.4
  • 58
    • 0344827287 scopus 로고    scopus 로고
    • Evolution of a combinatorial transcriptional circuit: a case study in yeasts
    • Tsong, A.E., Miller, M.G., Raisner, R.M., and Johnson, A.D. (2003) Evolution of a combinatorial transcriptional circuit: a case study in yeasts. Cell 115: 389-399.
    • (2003) Cell , vol.115 , pp. 389-399
    • Tsong, A.E.1    Miller, M.G.2    Raisner, R.M.3    Johnson, A.D.4
  • 59
    • 52749097035 scopus 로고    scopus 로고
    • Using RSAT to scan genome sequences for transcription factor binding sites and cis-regulatory modules
    • Turatsinze, J.-V., Thomas-Chollier, M., Defrance, M., and Van Helden, J. (2008) Using RSAT to scan genome sequences for transcription factor binding sites and cis-regulatory modules. Nat Protoc 3: 1578-1588.
    • (2008) Nat Protoc , vol.3 , pp. 1578-1588
    • Turatsinze, J.-V.1    Thomas-Chollier, M.2    Defrance, M.3    Van Helden, J.4
  • 61
    • 84864056939 scopus 로고    scopus 로고
    • The link between morphotype transition and virulence in Cryptococcus neoformans
    • Wang, L., Zhai, B., and Lin, X. (2012) The link between morphotype transition and virulence in Cryptococcus neoformans. PLoS Pathog 8: e1002765.
    • (2012) PLoS Pathog , vol.8 , pp. e1002765
    • Wang, L.1    Zhai, B.2    Lin, X.3
  • 62
    • 78349241121 scopus 로고    scopus 로고
    • Sex-induced silencing defends the genome of Cryptococcus neoformans via RNAi
    • Wang, X., Hsueh, Y.-P., Li, W., Floyd, A., Skalsky, R., and Heitman, J. (2010) Sex-induced silencing defends the genome of Cryptococcus neoformans via RNAi. Genes & Dev 24: 2566-2582.
    • (2010) Genes & Dev , vol.24 , pp. 2566-2582
    • Wang, X.1    Hsueh, Y.-P.2    Li, W.3    Floyd, A.4    Skalsky, R.5    Heitman, J.6
  • 63
    • 0028069606 scopus 로고
    • Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: identification as a laccase
    • Williamson, P.R. (1994) Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: identification as a laccase. J Bacteriol 176: 656-664.
    • (1994) J Bacteriol , vol.176 , pp. 656-664
    • Williamson, P.R.1
  • 64
    • 4644240769 scopus 로고    scopus 로고
    • Role of laccase in the biology and virulence of Cryptococcus neoformans
    • Zhu, X., and Williamson, P.R. (2004) Role of laccase in the biology and virulence of Cryptococcus neoformans. FEMS Yeast Res 5: 1-10.
    • (2004) FEMS Yeast Res , vol.5 , pp. 1-10
    • Zhu, X.1    Williamson, P.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.