메뉴 건너뛰기




Volumn 191, Issue 2, 2012, Pages 435-449

Analysis of cryptococcus neoformans sexual development reveals rewiring of the pheromone-response network by a change in transcription factor identity

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; PHEROMONE; PHEROMONE RESPONSE ELEMENT; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MAT2; UNCLASSIFIED DRUG;

EID: 84862532332     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.112.138958     Document Type: Article
Times cited : (24)

References (80)
  • 2
    • 0030668723 scopus 로고    scopus 로고
    • Cryptococcus neoformans mating and virulence are regulated by the G-protein a subunit Gpa1 and cAMP
    • Alspaugh, J. A., J. R. Perfect, and J. Heitman, 1997 Cryptococcus neoformans mating and virulence are regulated by the G-protein a subunit Gpa1 and cAMP. Genes Dev. 11: 3206-3217.
    • (1997) Genes Dev , vol.11 , pp. 3206-3217
    • Alspaugh, J.A.1    Perfect, J.R.2    Heitman, J.3
  • 3
    • 0034069495 scopus 로고    scopus 로고
    • Gene ontology: Tool for the unification of biology: The Gene Ontology Consortium
    • Ashburner, M., C. A. Ball, J. A. Blake, D. Botstein, H. Butler et al., 2000 Gene ontology: tool for the unification of biology: The Gene Ontology Consortium. Nat. Genet. 25: 25-29.
    • (2000) Nat. Genet , vol.25 , pp. 25-29
    • Ashburner, M.1    Ball, C.A.2    Blake, J.A.3    Botstein, D.4    Butler, H.5
  • 6
    • 0031877016 scopus 로고    scopus 로고
    • Combining evidence using pvalues: Application to sequence homology searches
    • Bailey, T. L., and M. Gribskov, 1998 Combining evidence using pvalues: application to sequence homology searches. Bioinformatics 14: 48-54.
    • (1998) Bioinformatics , vol.14 , pp. 48-54
    • Bailey, T.L.1    Gribskov, M.2
  • 7
    • 79956293316 scopus 로고    scopus 로고
    • Extensive DNAbinding specificity divergence of a conserved transcription regulator
    • Baker, C. R., B. B. Tuch, and A. D. Johnson, 2011 Extensive DNAbinding specificity divergence of a conserved transcription regulator. Proc. Natl. Acad. Sci. USA 108: 7493-7498.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 7493-7498
    • Baker, C.R.1    Tuch, B.B.2    Johnson, A.D.3
  • 8
    • 78650344876 scopus 로고    scopus 로고
    • Intercalation of a new tier of transcription regulation into an ancient circuit
    • Booth, L. N., B. B. Tuch, and A. D. Johnson, 2010 Intercalation of a new tier of transcription regulation into an ancient circuit. Nature 468: 959-963.
    • (2010) Nature , vol.468 , pp. 959-963
    • Booth, L.N.1    Tuch, B.B.2    Johnson, A.D.3
  • 9
    • 34547874585 scopus 로고    scopus 로고
    • Divergence of transcription factor binding sites across related yeast species
    • Borneman, A. R., T. A. Gianoulis, Z. D. Zhang, H. Yu, J. Rozowsky et al., 2007 Divergence of transcription factor binding sites across related yeast species. Science 317: 815-819.
    • (2007) Science , vol.317 , pp. 815-819
    • Borneman, A.R.1    Gianoulis, T.A.2    Zhang, Z.D.3    Yu, H.4    Rozowsky, J.5
  • 10
    • 78449231932 scopus 로고    scopus 로고
    • Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite
    • Campbell, T. L., E. K. de Silva, K. L. Olszewski, O. Elemento, and M. Llinás, 2010 Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite. PLoS Pathog. 6: e1001165.
    • (2010) PLoS Pathog , vol.6
    • Campbell, T.L.1    de Silva, E.K.2    Olszewski, K.L.3    Elemento, O.4    Llinás, M.5
  • 11
    • 0034610855 scopus 로고    scopus 로고
    • Cryptococcus neoformans STE12a regulates virulence but is not essential for mating
    • Chang, Y. C., B. L. Wickes, G. F. Miller, L. A. Penoyer, and K. J. Kwon-Chung, 2000 Cryptococcus neoformans STE12a regulates virulence but is not essential for mating. J. Exp. Med. 191: 871-882.
    • (2000) J. Exp. Med , vol.191 , pp. 871-882
    • Chang, Y.C.1    Wickes, B.L.2    Miller, G.F.3    Penoyer, L.A.4    Kwon-Chung, K.J.5
  • 12
    • 0035853109 scopus 로고    scopus 로고
    • The second STE12 homologue of Cryptococcus neoformans is MATaspecific and plays an important role in virulence
    • Chang, Y. C., L. A. Penoyer, and K. J. Kwon-Chung, 2001 The second STE12 homologue of Cryptococcus neoformans is MATaspecific and plays an important role in virulence. Proc. Natl. Acad. Sci. USA 98: 3258-3263.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 3258-3263
    • Chang, Y.C.1    Penoyer, L.A.2    Kwon-Chung, K.J.3
  • 13
    • 0036616588 scopus 로고    scopus 로고
    • Molecular analysis of CPRa, a MATa-specific pheromone receptor gene of Cryptococcus neoformans
    • Chung, S., M. Karos, Y. C. Chang, J. Lukszo, B. L. Wickes et al., 2002 Molecular analysis of CPRa, a MATa-specific pheromone receptor gene of Cryptococcus neoformans. Eukaryot. Cell 1: 432-439.
    • (2002) Eukaryot. Cell , vol.1 , pp. 432-439
    • Chung, S.1    Karos, M.2    Chang, Y.C.3    Lukszo, J.4    Wickes, B.L.5
  • 16
    • 0034353287 scopus 로고    scopus 로고
    • Characterization of the MFa pheromone of the human fungal pathogen Cryptococcus neoformans
    • Davidson, R. C., T. D. Moore, A. R. Odom, and J. Heitman, 2000 Characterization of the MFa pheromone of the human fungal pathogen Cryptococcus neoformans. Mol. Microbiol. 38: 1017-1026.
    • (2000) Mol. Microbiol , vol.38 , pp. 1017-1026
    • Davidson, R.C.1    Moore, T.D.2    Odom, A.R.3    Heitman, J.4
  • 17
    • 0036667448 scopus 로고    scopus 로고
    • A PCR-based strategy to generate integrative targeting alleles with large regions of homology
    • Davidson, R. C., J. R. Blankenship, P. R. Kraus, M. de Jesus Berrios, C. M. Hull et al., 2002 A PCR-based strategy to generate integrative targeting alleles with large regions of homology. Microbiology 148: 2607-2615.
    • (2002) Microbiology , vol.148 , pp. 2607-2615
    • Davidson, R.C.1    Blankenship, J.R.2    Kraus, P.R.3    de Jesus, B.M.4    Hull, C.M.5
  • 18
    • 0037487244 scopus 로고    scopus 로고
    • A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans
    • Davidson, R., C. Nichols, G. Cox, J. Perfect, and J. Heitman, 2003 A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans. Mol. Microbiol. 49: 469-485.
    • (2003) Mol. Microbiol , vol.49 , pp. 469-485
    • Davidson, R.1    Nichols, C.2    Cox, G.3    Perfect, J.4    Heitman, J.5
  • 20
    • 0034923514 scopus 로고    scopus 로고
    • Regulation of G proteininitiated signal transduction in yeast: Paradigms and principles
    • Dohlman, H. G., and J. W. Thorner, 2001 Regulation of G proteininitiated signal transduction in yeast: paradigms and principles. Annu. Rev. Biochem. 70: 703-754.
    • (2001) Annu. Rev. Biochem , vol.70 , pp. 703-754
    • Dohlman, H.G.1    Thorner, J.W.2
  • 21
    • 0024710930 scopus 로고
    • The yeast Ste12 protein binds to the DNA sequence mediating pheromone induction
    • Dolan, J. W., C. Kirkman, and S. Fields, 1989 The yeast Ste12 protein binds to the DNA sequence mediating pheromone induction. Proc. Natl. Acad. Sci. USA 86: 5703-5707.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 5703-5707
    • Dolan, J.W.1    Kirkman, C.2    Fields, S.3
  • 22
    • 40649108877 scopus 로고    scopus 로고
    • Sexual development in Cryptococcus neoformans requires CLP1, a target of the homeodomain transcription factors Sxi1a and Sxi2a
    • Ekena, J., B. Stanton, J. Schiebe-Owens, and C. Hull, 2008 Sexual development in Cryptococcus neoformans requires CLP1, a target of the homeodomain transcription factors Sxi1a and Sxi2a. Eukaryot. Cell 7: 49-57.
    • (2008) Eukaryot. Cell , vol.7 , pp. 49-57
    • Ekena, J.1    Stanton, B.2    Schiebe-Owens, J.3    Hull, C.4
  • 23
    • 0024724818 scopus 로고
    • Ste12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes
    • Errede, B., and G. Ammerer, 1989 Ste12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes. Genes Dev. 3: 1349-1361.
    • (1989) Genes Dev , vol.3 , pp. 1349-1361
    • Errede, B.1    Ammerer, G.2
  • 24
    • 0022132981 scopus 로고
    • The yeast Ste12 product is required for expression of two sets of cell-type specific genes
    • Fields, S., and I. Herskowitz, 1985 The yeast Ste12 product is required for expression of two sets of cell-type specific genes. Cell 42: 923-930.
    • (1985) Cell , vol.42 , pp. 923-930
    • Fields, S.1    Herskowitz, I.2
  • 26
    • 14044252090 scopus 로고    scopus 로고
    • Conservation and evolution of cis-regulatory systems in ascomycete fungi
    • Gasch, A. P., A. M. Moses, D. Y. Chiang, H. B. Fraser, M. Berardini et al., 2004 Conservation and evolution of cis-regulatory systems in ascomycete fungi. PLoS Biol. 2: e398.
    • (2004) PLoS Biol , vol.2
    • Gasch, A.P.1    Moses, A.M.2    Chiang, D.Y.3    Fraser, H.B.4    Berardini, M.5
  • 27
  • 28
    • 0030853763 scopus 로고    scopus 로고
    • Meta-MEME: Motif-based hidden Markov models of protein families
    • Grundy, W. N., T. L. Bailey, C. P. Elkan, and M. E. Baker, 1997 Meta-MEME: motif-based hidden Markov models of protein families. Comput. Appl. Biosci. 13: 397-406.
    • (1997) Comput. Appl. Biosci , vol.13 , pp. 397-406
    • Grundy, W.N.1    Bailey, T.L.2    Elkan, C.P.3    Baker, M.E.4
  • 29
    • 0025865002 scopus 로고
    • Pheromone response elements are necessary and sufficient for basal and pheromone-induced transcription of the FUS1 gene of Saccharomyces cerevisiae
    • Hagen, D. C., G. McCaffrey, and G. F. Sprague, 1991 Pheromone response elements are necessary and sufficient for basal and pheromone-induced transcription of the FUS1 gene of Saccharomyces cerevisiae. Mol. Cell. Biol. 11: 2952-2961.
    • (1991) Mol. Cell. Biol , vol.11 , pp. 2952-2961
    • Hagen, D.C.1    McCaffrey, G.2    Sprague, G.F.3
  • 30
    • 0029937938 scopus 로고    scopus 로고
    • The pheromone response factor coordinates filamentous growth and pathogenicity in Ustilago maydis
    • Hartmann, H. A., R. Kahmann, and M. Bölker, 1996 The pheromone response factor coordinates filamentous growth and pathogenicity in Ustilago maydis. EMBO J. 15: 1632-1641.
    • (1996) EMBO J , vol.15 , pp. 1632-1641
    • Hartmann, H.A.1    Kahmann, R.2    Bölker, M.3
  • 31
    • 0022163443 scopus 로고
    • A master regulatory locus that determines cell specialization in yeast
    • Herskowitz, I., 1985 A master regulatory locus that determines cell specialization in yeast. Harvey Lect. 81: 67-92.
    • (1985) Harvey Lect , vol.81 , pp. 67-92
    • Herskowitz, I.1
  • 32
    • 0024244073 scopus 로고
    • Life cycle of the budding yeast Saccharomyces cerevisiae
    • Herskowitz, I., 1988 Life cycle of the budding yeast Saccharomyces cerevisiae. Microbiol. Rev. 52: 536-553.
    • (1988) Microbiol. Rev , vol.52 , pp. 536-553
    • Herskowitz, I.1
  • 33
    • 74249093221 scopus 로고    scopus 로고
    • A phenotypic profile of the Candida albicans regulatory network
    • Homann, O. R., J. Dea, S. M. Noble, and A. D. Johnson, 2009 A phenotypic profile of the Candida albicans regulatory network. PLoS Genet. 5: e1000783.
    • (2009) PLoS Genet , vol.5
    • Homann, O.R.1    Dea, J.2    Noble, S.M.3    Johnson, A.D.4
  • 34
    • 13744249299 scopus 로고    scopus 로고
    • A homolog of Ste6, the afactor transporter in Saccharomyces cerevisiae, is required for mating but not for monokaryotic fruiting in Cryptococcus neoformans
    • Hsueh, Y. P., and W. C. Shen, 2005 A homolog of Ste6, the afactor transporter in Saccharomyces cerevisiae, is required for mating but not for monokaryotic fruiting in Cryptococcus neoformans. Eukaryot. Cell 4: 147-155.
    • (2005) Eukaryot. Cell , vol.4 , pp. 147-155
    • Hsueh, Y.P.1    Shen, W.C.2
  • 35
    • 34548478560 scopus 로고    scopus 로고
    • G protein signaling governing cell fate decisions involves opposing Ga subunits in Cryptococcus neoformans
    • Hsueh, Y. P., C. Xue, and J. Heitman, 2007 G protein signaling governing cell fate decisions involves opposing Ga subunits in Cryptococcus neoformans. Mol. Biol. Cell 18: 3237-3249.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 3237-3249
    • Hsueh, Y.P.1    Xue, C.2    Heitman, J.3
  • 36
    • 65649135441 scopus 로고    scopus 로고
    • A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans
    • Hsueh, Y. P., C. Xue, and J. Heitman, 2009 A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans. EMBO J. 28: 1220-1233.
    • (2009) EMBO J , vol.28 , pp. 1220-1233
    • Hsueh, Y.P.1    Xue, C.2    Heitman, J.3
  • 37
    • 0036948447 scopus 로고    scopus 로고
    • Genetics of Cryptococcus neoformans
    • Hull, C., and J. Heitman, 2002 Genetics of Cryptococcus neoformans. Annu. Rev. Genet. 36: 557-615.
    • (2002) Annu. Rev. Genet , vol.36 , pp. 557-615
    • Hull, C.1    Heitman, J.2
  • 38
    • 0036894726 scopus 로고    scopus 로고
    • Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1a
    • Hull, C., R. Davidson, and J. Heitman, 2002 Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1a. GenesDev. 16: 3046-3060.
    • (2002) GenesDev , vol.16 , pp. 3046-3060
    • Hull, C.1    Davidson, R.2    Heitman, J.3
  • 39
    • 77955419577 scopus 로고    scopus 로고
    • A tetrad analysis of the basidiomycete fungus Cryptococcus neoformans
    • Idnurm, A., 2010 A tetrad analysis of the basidiomycete fungus Cryptococcus neoformans. Genetics 185: 153-163.
    • (2010) Genetics , vol.185 , pp. 153-163
    • Idnurm, A.1
  • 40
    • 0035103777 scopus 로고    scopus 로고
    • Rfg1, a protein related to the Saccharomyces cerevisiae hypoxic regulator Rox1, controls filamentous growth and virulence in Candida albicans
    • Kadosh, D., and A. D. Johnson, 2001 Rfg1, a protein related to the Saccharomyces cerevisiae hypoxic regulator Rox1, controls filamentous growth and virulence in Candida albicans. Mol. Cell. Biol. 21: 2496-2505.
    • (2001) Mol. Cell. Biol , vol.21 , pp. 2496-2505
    • Kadosh, D.1    Johnson, A.D.2
  • 41
    • 75149119287 scopus 로고    scopus 로고
    • Septins enforce morphogenetic events during sexual reproduction and contribute to virulence of Cryptococcus neoformans
    • Kozubowski, L., and J. Heitman, 2010 Septins enforce morphogenetic events during sexual reproduction and contribute to virulence of Cryptococcus neoformans. Mol. Microbiol. 75: 658-675.
    • (2010) Mol. Microbiol , vol.75 , pp. 658-675
    • Kozubowski, L.1    Heitman, J.2
  • 42
    • 0016975715 scopus 로고
    • Morphogenesis of Filobasidiella neoformans, the sexual state of Cryptococcus neoformans
    • Kwon-Chung, K. J., 1976 Morphogenesis of Filobasidiella neoformans, the sexual state of Cryptococcus neoformans. Mycologia 68: 821-833.
    • (1976) Mycologia , vol.68 , pp. 821-833
    • Kwon-Chung, K.J.1
  • 43
    • 0026334016 scopus 로고
    • Genetic association of mating types and virulence in Cryptococcus neoformans
    • Kwon-Chung, K. J., J. C. Edman, and B. L. Wickes, 1992 Genetic association of mating types and virulence in Cryptococcus neoformans. Infect. Immun. 60: 602-605.
    • (1992) Infect. Immun , vol.60 , pp. 602-605
    • Kwon-Chung, K.J.1    Edman, J.C.2    Wickes, B.L.3
  • 44
    • 77950553742 scopus 로고    scopus 로고
    • Evolutionary tinkering with conserved components of a transcriptional regulatory network
    • Lavoie, H., H. Hogues, J. Mallick, A. Sellam, A. Nantel et al., 2010 Evolutionary tinkering with conserved components of a transcriptional regulatory network. PLoS Biol. 8: e1000329.
    • (2010) PLoS Biol , vol.8
    • Lavoie, H.1    Hogues, H.2    Mallick, J.3    Sellam, A.4    Nantel, A.5
  • 45
    • 77953192777 scopus 로고    scopus 로고
    • Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite- and same-sex mating in Cryptococcus neoformans
    • Lin, X., J. C. Jackson, M. Feretzaki, C. Xue, and J. Heitman, 2010 Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite- and same-sex mating in Cryptococcus neoformans. PLoS Genet. 6: e1000953.
    • (2010) PLoS Genet , vol.6
    • Lin, X.1    Jackson, J.C.2    Feretzaki, M.3    Xue, C.4    Heitman, J.5
  • 46
    • 0346468275 scopus 로고
    • Oxygen regulation of anaerobic and aerobic genes mediated by a common factor inyeast
    • Lowry, C. V., and R. S. Zitomer, 1984 Oxygen regulation of anaerobic and aerobic genes mediated by a common factor inyeast. Proc. Natl. Acad. Sci. USA 81: 6129-6133.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 6129-6133
    • Lowry, C.V.1    Zitomer, R.S.2
  • 48
    • 0036886328 scopus 로고    scopus 로고
    • Many of the genes required for mating in Saccharomyces cerevisiae are also required for mating in Candida albicans
    • Magee, B. B., M. Legrand, A. M. Alarco, M. Raymond, and P. T. Magee, 2002 Many of the genes required for mating in Saccharomyces cerevisiae are also required for mating in Candida albicans. Mol. Microbiol. 46: 1345-1351.
    • (2002) Mol. Microbiol , vol.46 , pp. 1345-1351
    • Magee, B.B.1    Legrand, M.2    Alarco, A.M.3    Raymond, M.4    Magee, P.T.5
  • 49
    • 27744507812 scopus 로고    scopus 로고
    • APP1 transcription is regulated by inositolphosphorylceramide synthase 1-diacylglycerol pathway and is controlled by Atf2 transcription factor in Cryptococcus neoformans
    • Mare, L., R. Iatta, M. T. Montagna, C. Luberto, and M. Del Poeta, 2005 APP1 transcription is regulated by inositolphosphorylceramide synthase 1-diacylglycerol pathway and is controlled by Atf2 transcription factor in Cryptococcus neoformans. J. Biol. Chem. 280: 36055-36064.
    • (2005) J. Biol. Chem , vol.280 , pp. 36055-36064
    • Mare, L.1    Iatta, R.2    Montagna, M.T.3    Luberto, C.4    del Poeta, M.5
  • 50
    • 34250204870 scopus 로고    scopus 로고
    • Transcriptional rewiring of fungal galactose-metabolism circuitry
    • Martchenko, M., A. Levitin, H. Hogues, A. Nantel, and M. Whiteway, 2007 Transcriptional rewiring of fungal galactose-metabolism circuitry. Curr. Biol. 17: 1007-1013.
    • (2007) Curr. Biol , vol.17 , pp. 1007-1013
    • Martchenko, M.1    Levitin, A.2    Hogues, H.3    Nantel, A.4    Whiteway, M.5
  • 52
    • 0023729456 scopus 로고
    • Role of STE genes in the mating factor signaling pathway mediated by GPA1 in Saccharomyces cerevisiae
    • Nakayama, N., Y. Kaziro, K. Arai, and K. Matsumoto, 1988 Role of STE genes in the mating factor signaling pathway mediated by GPA1 in Saccharomyces cerevisiae. Mol. Cell. Biol. 8: 3777-3783.
    • (1988) Mol. Cell. Biol , vol.8 , pp. 3777-3783
    • Nakayama, N.1    Kaziro, Y.2    Arai, K.3    Matsumoto, K.4
  • 54
    • 84856117019 scopus 로고    scopus 로고
    • A recently evolved transcriptional network controls biofilm development in Candida albicans
    • Nobile, C. J., E. P. Fox, J. E. Nett, T. R. Sorrells, Q. M. Mitrovich et al., 2012 A recently evolved transcriptional network controls biofilm development in Candida albicans. Cell 148: 126-138.
    • (2012) Cell , vol.148 , pp. 126-138
    • Nobile, C.J.1    Fox, E.P.2    Nett, J.E.3    Sorrells, T.R.4    Mitrovich, Q.M.5
  • 55
    • 0022994652 scopus 로고
    • RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone afactor
    • Powers, S., S. Michaelis, D. Broek, S. Santa Anna, J. Field et al., 1986 RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone afactor. Cell 47: 413-422.
    • (1986) Cell , vol.47 , pp. 413-422
    • Powers, S.1    Michaelis, S.2    Broek, D.3    Santa, A.S.4    Field, J.5
  • 56
    • 0035375137 scopus 로고    scopus 로고
    • Computational analysis of microarray data
    • Quackenbush, J., 2001 Computational analysis of microarray data. Nat. Rev. Genet. 2: 418-427.
    • (2001) Nat. Rev. Genet , vol.2 , pp. 418-427
    • Quackenbush, J.1
  • 58
    • 73349089654 scopus 로고    scopus 로고
    • Genes selectively up-regulated by pheromone in white cells are involved in biofilm formation in Candida albicans
    • Sahni, N., S. Yi, K. J. Daniels, T. Srikantha, C. Pujol et al., 2009 Genes selectively up-regulated by pheromone in white cells are involved in biofilm formation in Candida albicans. PLoS Pathog. 5: e1000601.
    • (2009) PLoS Pathog , vol.5
    • Sahni, N.1    Yi, S.2    Daniels, K.J.3    Srikantha, T.4    Pujol, C.5
  • 59
    • 77952902149 scopus 로고    scopus 로고
    • Tec1 mediates the pheromone response of the white phenotype of Candida albicans: Insights into the evolution of new signal transduction pathways
    • Sahni, N., S. Yi, K. J. Daniels, G. Huang, T. Srikantha et al., 2010 Tec1 mediates the pheromone response of the white phenotype of Candida albicans: insights into the evolution of new signal transduction pathways. PLoS Biol. 8: e1000363.
    • (2010) PLoS Biol , vol.8
    • Sahni, N.1    Yi, S.2    Daniels, K.J.3    Huang, G.4    Srikantha, T.5
  • 60
    • 0025221001 scopus 로고
    • The PRE and PQ box are functionally distinct yeast pheromone response elements
    • Sengupta, P., and B. H. Cochran, 1990 The PRE and PQ box are functionally distinct yeast pheromone response elements. Mol. Cell. Biol. 10: 6809-6812.
    • (1990) Mol. Cell. Biol , vol.10 , pp. 6809-6812
    • Sengupta, P.1    Cochran, B.H.2
  • 61
    • 0036615226 scopus 로고    scopus 로고
    • Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans
    • Shen, W. C., R. C. Davidson, G. M. Cox, and J. Heitman, 2002 Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans. Eukaryot. Cell 1: 366-377.
    • (2002) Eukaryot. Cell , vol.1 , pp. 366-377
    • Shen, W.C.1    Davidson, R.C.2    Cox, G.M.3    Heitman, J.4
  • 62
    • 0025978949 scopus 로고
    • Getting started with yeast
    • edited by C. Guthrie, and G. Fink. Academic Press, San Diego, CA
    • Sherman, F., 1991 Getting started with yeast, pp. 3-21 in Methods in Enzymology, edited by C. Guthrie, and G. Fink. Academic Press, San Diego, CA.
    • (1991) Methods In Enzymology , pp. 3-21
    • Sherman, F.1
  • 63
    • 0025764889 scopus 로고
    • Pheromonedependent phosphorylation of the yeast Ste12 protein correlates with transcriptional activation
    • Song, D., J. W. Dolan, Y. L. Yuan, and S. Fields, 1991 Pheromonedependent phosphorylation of the yeast Ste12 protein correlates with transcriptional activation. Genes Dev. 5: 741-750.
    • (1991) Genes Dev , vol.5 , pp. 741-750
    • Song, D.1    Dolan, J.W.2    Yuan, Y.L.3    Fields, S.4
  • 64
    • 77649178986 scopus 로고    scopus 로고
    • Characterizing the role of the microtubule binding protein Bim1 in Cryptococcus neoformans
    • Staudt, M., E. Kruzel, K. Shimizu, and C. Hull, 2010 Characterizing the role of the microtubule binding protein Bim1 in Cryptococcus neoformans. Fungal Genet. Biol. 47: 310-317.
    • (2010) Fungal Genet. Biol , vol.47 , pp. 310-317
    • Staudt, M.1    Kruzel, E.2    Shimizu, K.3    Hull, C.4
  • 65
    • 77954742834 scopus 로고    scopus 로고
    • Organizational constraints on Ste12 cis-elements for a pheromone response in Saccharomyces cerevisiae
    • Su, T.-C., E. Tamarkina, and I. Sadowski, 2010 Organizational constraints on Ste12 cis-elements for a pheromone response in Saccharomyces cerevisiae. FEBS J. 277: 3235-3248.
    • (2010) FEBS J , vol.277 , pp. 3235-3248
    • Su, T.-C.1    Tamarkina, E.2    Sadowski, I.3
  • 66
    • 0026038558 scopus 로고
    • Schizosaccharomyces pombe ste11+ encodes a transcription factor with an HMG motif that is a critical regulator of sexual development
    • Sugimoto, A., Y. Iino, T. Maeda, Y. Watanabe, and M. Yamamoto, 1991 Schizosaccharomyces pombe ste11+ encodes a transcription factor with an HMG motif that is a critical regulator of sexual development. Genes Dev. 5: 1990-1999.
    • (1991) Genes Dev , vol.5 , pp. 1990-1999
    • Sugimoto, A.1    Iino, Y.2    Maeda, T.3    Watanabe, Y.4    Yamamoto, M.5
  • 67
    • 73349095713 scopus 로고    scopus 로고
    • Roles of trans and cis variation in yeast intraspecies evolution of gene expression
    • Sung, H.-M., T.-Y. Wang, D. Wang, Y.-S. Huang, and J.-P. Wu et al., 2009 Roles of trans and cis variation in yeast intraspecies evolution of gene expression. Mol. Biol. Evol. 26: 2533-2538.
    • (2009) Mol. Biol. Evol , vol.26 , pp. 2533-2538
    • Sung, H.-M.1    Wang, T.-Y.2    Wang, D.3    Huang, Y.-S.4    Wu, J.-P.5
  • 68
    • 0027467293 scopus 로고
    • Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA
    • Toffaletti, D. L., T. H. Rude, S. A. Johnston, D. T. Durack, and J. R. Perfect, 1993 Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA. J. Bacteriol. 175: 1405-1411.
    • (1993) J. Bacteriol , vol.175 , pp. 1405-1411
    • Toffaletti, D.L.1    Rude, T.H.2    Johnston, S.A.3    Durack, D.T.4    Perfect, J.R.5
  • 69
    • 41449101718 scopus 로고    scopus 로고
    • Atf2 transcription factor binds to the APP1 promoter inCryptococcus neoformans: Stimulatory effect of diacylglycerol
    • Tommasino, N., M. Villani, A. Qureshi, J. Henry, C. Luberto et al., 2008 Atf2 transcription factor binds to the APP1 promoter inCryptococcus neoformans: stimulatory effect of diacylglycerol. Eukaryot. Cell 7: 294-301.
    • (2008) Eukaryot. Cell , vol.7 , pp. 294-301
    • Tommasino, N.1    Villani, M.2    Qureshi, A.3    Henry, J.4    Luberto, C.5
  • 70
    • 0344827287 scopus 로고    scopus 로고
    • Evolution of a combinatorial transcriptional circuit: A case study in yeasts
    • Tsong, A., M. Miller, R. Raisner, and A. Johnson, 2003 Evolution of a combinatorial transcriptional circuit: a case study in yeasts. Cell 115: 389-399.
    • (2003) Cell , vol.115 , pp. 389-399
    • Tsong, A.1    Miller, M.2    Raisner, R.3    Johnson, A.4
  • 71
    • 33749173831 scopus 로고    scopus 로고
    • Evolution of alternative transcriptional circuits with identical logic
    • Tsong, A., B. Tuch, H. Li, and A. Johnson, 2006 Evolution of alternative transcriptional circuits with identical logic. Nature 443: 415-420.
    • (2006) Nature , vol.443 , pp. 415-420
    • Tsong, A.1    Tuch, B.2    Li, H.3    Johnson, A.4
  • 72
    • 2442695651 scopus 로고    scopus 로고
    • Identification of the pheromone response element in Ustilago maydis
    • Urban, M., R. Kahmann, and M. Bölker, 1996 Identification of the pheromone response element in Ustilago maydis. Mol. Gen. Genet. 251: 31-37.
    • (1996) Mol. Gen. Genet , vol.251 , pp. 31-37
    • Urban, M.1    Kahmann, R.2    Bölker, M.3
  • 73
    • 3142752754 scopus 로고    scopus 로고
    • The RAM1 gene encoding a protein-farnesyltransferase b-subunit homologue is essential in Cryptococcus neoformans
    • Vallim, M. A., L. Fernandes, and J. A. Alspaugh, 2004 The RAM1 gene encoding a protein-farnesyltransferase b-subunit homologue is essential in Cryptococcus neoformans. Microbiology 150: 1925-1935.
    • (2004) Microbiology , vol.150 , pp. 1925-1935
    • Vallim, M.A.1    Fernandes, L.2    Alspaugh, J.A.3
  • 74
    • 20444488798 scopus 로고    scopus 로고
    • A Rac homolog functions downstream of Ras1 to control hyphal differentiation and high-temperature growth in the pathogenic fungus Cryptococcus neoformans
    • Vallim, M. A., C. B. Nichols, L. Fernandes, K. L. Cramer, and J. A. Alspaugh, 2005 A Rac homolog functions downstream of Ras1 to control hyphal differentiation and high-temperature growth in the pathogenic fungus Cryptococcus neoformans. Eukaryot. Cell 4: 1066-1078.
    • (2005) Eukaryot. Cell , vol.4 , pp. 1066-1078
    • Vallim, M.A.1    Nichols, C.B.2    Fernandes, L.3    Cramer, K.L.4    Alspaugh, J.A.5
  • 75
    • 0026019629 scopus 로고
    • Identification and cloning of TCF-1, a T lymphocytespecifictranscription factor containing a sequence-specific HMG box
    • van de Wetering, M., M. Oosterwegel, D. Dooijes, and H. Clevers, 1991 Identification and cloning of TCF-1, a T lymphocytespecifictranscription factor containing a sequence-specific HMG box. EMBO J. 10: 123-132.
    • (1991) EMBO J , vol.10 , pp. 123-132
    • van de Wetering, M.1    Oosterwegel, M.2    Dooijes, D.3    Clevers, H.4
  • 76
    • 0030608657 scopus 로고    scopus 로고
    • The Cryptococcus neoformans STE12a gene: A putative Saccharomyces cerevisiae STE12 homologue that is mating type specific
    • Wickes, B. L., U. Edman, and J. C. Edman, 1997 The Cryptococcus neoformans STE12a gene: a putative Saccharomyces cerevisiae STE12 homologue that is mating type specific. Mol. Microbiol. 26: 951-960.
    • (1997) Mol. Microbiol , vol.26 , pp. 951-960
    • Wickes, B.L.1    Edman, U.2    Edman, J.C.3
  • 77
    • 77951259297 scopus 로고    scopus 로고
    • Challenges for modeling global gene regulatory networks during development: Insights from Drosophila
    • Wilczynski, B., and E. E. Furlong, 2010 Challenges for modeling global gene regulatory networks during development: insights from Drosophila. Dev. Biol. 340: 161-169.
    • (2010) Dev. Biol , vol.340 , pp. 161-169
    • Wilczynski, B.1    Furlong, E.E.2
  • 78
    • 0032585880 scopus 로고    scopus 로고
    • The STE12a homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans
    • Yue, C., L. M. Cavallo, J. A. Alspaugh, P. Wang, G. M. Cox et al., 1999 The STE12a homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans. Genetics 153: 1601-1615.
    • (1999) Genetics , vol.153 , pp. 1601-1615
    • Yue, C.1    Cavallo, L.M.2    Alspaugh, J.A.3    Wang, P.4    Cox, G.M.5
  • 79
    • 0033580279 scopus 로고    scopus 로고
    • The yeast Cryptococcus neoformans uses "mammalian" enhancer sites in the regulation of the virulence gene, CNLAC1
    • Zhang, S., A. Varma, and P. R. Williamson, 1999 The yeast Cryptococcus neoformans uses "mammalian" enhancer sites in the regulation of the virulence gene, CNLAC1. Gene 227: 231-240.
    • (1999) Gene , vol.227 , pp. 231-240
    • Zhang, S.1    Varma, A.2    Williamson, P.R.3
  • 80
    • 33750460638 scopus 로고    scopus 로고
    • The Hsp70 member, Ssa1, acts as a DNA-binding transcriptional co-activator of laccase in Cryptococcus neoformans
    • Zhang, S., M. Hacham, J. Panepinto, G. Hu, S. Shin et al., 2006 The Hsp70 member, Ssa1, acts as a DNA-binding transcriptional co-activator of laccase in Cryptococcus neoformans. Mol. Microbiol. 62: 1090-1101.
    • (2006) Mol. Microbiol , vol.62 , pp. 1090-1101
    • Zhang, S.1    Hacham, M.2    Panepinto, J.3    Hu, G.4    Shin, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.