메뉴 건너뛰기




Volumn 8, Issue 6, 2012, Pages

The link between morphotype transition and virulence in Cryptococcus neoformans

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; PHEROMONE; PROTEIN CFL1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZNF2; UNCLASSIFIED DRUG; FUNGAL PROTEIN;

EID: 84864056939     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002765     Document Type: Article
Times cited : (111)

References (69)
  • 2
    • 33646253928 scopus 로고    scopus 로고
    • Global control of dimorphism and virulence in fungi
    • Nemecek JC, Wuthrich M, Klein BS, (2006) Global control of dimorphism and virulence in fungi. Science 312: 583-588.
    • (2006) Science , vol.312 , pp. 583-588
    • Nemecek, J.C.1    Wuthrich, M.2    Klein, B.S.3
  • 3
    • 42449127140 scopus 로고    scopus 로고
    • Temperature-induced switch to the pathogenic yeast form of Histoplasma capsulatum requires Ryp1, a conserved transcriptional regulator
    • Nguyen VQ, Sil A, (2008) Temperature-induced switch to the pathogenic yeast form of Histoplasma capsulatum requires Ryp1, a conserved transcriptional regulator. Proc Natl Acad Sci U S A 105: 4880-4885.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 4880-4885
    • Nguyen, V.Q.1    Sil, A.2
  • 4
    • 55749094360 scopus 로고    scopus 로고
    • Conserved factors Ryp2 and Ryp3 control cell morphology and infectious spore formation in the fungal pathogen Histoplasma capsulatum
    • Webster RH, Sil A, (2008) Conserved factors Ryp2 and Ryp3 control cell morphology and infectious spore formation in the fungal pathogen Histoplasma capsulatum. Proc Natl Acad Sci U S A 105: 14573-14578.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14573-14578
    • Webster, R.H.1    Sil, A.2
  • 5
    • 0017581861 scopus 로고
    • Development of arthrospores of Trichophyton mentagrophytes
    • Bibel DJ, Crumrine DA, Yee K, King RD, (1977) Development of arthrospores of Trichophyton mentagrophytes. Infect Immun 15: 958-971.
    • (1977) Infect Immun , vol.15 , pp. 958-971
    • Bibel, D.J.1    Crumrine, D.A.2    Yee, K.3    King, R.D.4
  • 6
    • 77956851876 scopus 로고    scopus 로고
    • Disseminated dermal Trichophyton rubrum infection - an expression of dermatophyte dimorphism?
    • Lillis JV, Dawson ES, Chang R, White CR Jr, (2010) Disseminated dermal Trichophyton rubrum infection- an expression of dermatophyte dimorphism? J Cutan Pathol 37: 1168-1169.
    • (2010) J Cutan Pathol , vol.37 , pp. 1168-1169
    • Lillis, J.V.1    Dawson, E.S.2    Chang, R.3    White Jr., C.R.4
  • 7
    • 77950560318 scopus 로고    scopus 로고
    • Disseminated dermatophytosis in a patient with hereditary hemochromatosis and hepatic cirrhosis: case report and review of the literature
    • Marconi VC, Kradin R, Marty FM, Hospenthal DR, Kotton CN, (2010) Disseminated dermatophytosis in a patient with hereditary hemochromatosis and hepatic cirrhosis: case report and review of the literature. Med Mycol 48: 518-527.
    • (2010) Med Mycol , vol.48 , pp. 518-527
    • Marconi, V.C.1    Kradin, R.2    Marty, F.M.3    Hospenthal, D.R.4    Kotton, C.N.5
  • 8
    • 67349215111 scopus 로고    scopus 로고
    • History of the discovery of the life cycle of Toxoplasma gondii
    • Dubey JP, (2009) History of the discovery of the life cycle of Toxoplasma gondii. Int J Parasitol 39: 877-882.
    • (2009) Int J Parasitol , vol.39 , pp. 877-882
    • Dubey, J.P.1
  • 9
    • 14044264288 scopus 로고    scopus 로고
    • The developmental cell biology of Trypanosoma brucei
    • Matthews KR, (2005) The developmental cell biology of Trypanosoma brucei. J Cell Sci 118: 283-290.
    • (2005) J Cell Sci , vol.118 , pp. 283-290
    • Matthews, K.R.1
  • 10
    • 62349130224 scopus 로고    scopus 로고
    • Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS
    • Park BJ, Wannemuehler KA, Marston BJ, Govender N, Pappas PG, et al. (2009) Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. AIDS 23: 525-530.
    • (2009) AIDS , vol.23 , pp. 525-530
    • Park, B.J.1    Wannemuehler, K.A.2    Marston, B.J.3    Govender, N.4    Pappas, P.G.5
  • 11
    • 68949105809 scopus 로고    scopus 로고
    • Cryptococcus neoformans: morphogenesis, infection, and evolution
    • Lin X, (2009) Cryptococcus neoformans: morphogenesis, infection, and evolution. Infect Genet Evol 9: 401-416.
    • (2009) Infect Genet Evol , vol.9 , pp. 401-416
    • Lin, X.1
  • 12
    • 0020630127 scopus 로고
    • Pathogenicity of the hyphae of Filobasidiella neoformans
    • Zimmer BL, Hempel HO, Goodman NL, (1983) Pathogenicity of the hyphae of Filobasidiella neoformans. Mycopathologia 81: 107-110.
    • (1983) Mycopathologia , vol.81 , pp. 107-110
    • Zimmer, B.L.1    Hempel, H.O.2    Goodman, N.L.3
  • 13
    • 0013912643 scopus 로고
    • Preliminary studies on a hypha-forming mutant of Cryptococcus neoformans
    • Shadomy HJ, Utz JP, (1966) Preliminary studies on a hypha-forming mutant of Cryptococcus neoformans. Mycologia 58: 383-390.
    • (1966) Mycologia , vol.58 , pp. 383-390
    • Shadomy, H.J.1    Utz, J.P.2
  • 14
    • 84907135329 scopus 로고
    • Histopathological observations in experimental cryptococcosis caused by a hypha-producing strain of Cryptococcus neoformans (Coward strain) in mice
    • Shadomy HJ, Lurie HI, (1971) Histopathological observations in experimental cryptococcosis caused by a hypha-producing strain of Cryptococcus neoformans (Coward strain) in mice. Sabouraudia 9: 6-9.
    • (1971) Sabouraudia , vol.9 , pp. 6-9
    • Shadomy, H.J.1    Lurie, H.I.2
  • 15
    • 84907132782 scopus 로고
    • Morphological variations of a hypha-forming strain of Cryptococcus neoformans (Coward strain) in tissues of mice
    • Lurie HI, Shadomy HJ, (1971) Morphological variations of a hypha-forming strain of Cryptococcus neoformans (Coward strain) in tissues of mice. Sabouraudia 9: 10-14.
    • (1971) Sabouraudia , vol.9 , pp. 10-14
    • Lurie, H.I.1    Shadomy, H.J.2
  • 16
    • 0018090329 scopus 로고
    • Cryptococcus neoformans: pseudohyphal forms surviving culture with Acanthamoeba polyphaga
    • Neilson JB, Ivey MH, Bulmer GS, (1978) Cryptococcus neoformans: pseudohyphal forms surviving culture with Acanthamoeba polyphaga. Infect Immun 20: 262-266.
    • (1978) Infect Immun , vol.20 , pp. 262-266
    • Neilson, J.B.1    Ivey, M.H.2    Bulmer, G.S.3
  • 17
    • 0019511322 scopus 로고
    • Pseudohyphal forms of Cryptococcus neoformans: decreased survival in vivo
    • Neilson JB, Fromtling RA, Bulmer GS, (1981) Pseudohyphal forms of Cryptococcus neoformans: decreased survival in vivo. Mycopathologia 73: 57-59.
    • (1981) Mycopathologia , vol.73 , pp. 57-59
    • Neilson, J.B.1    Fromtling, R.A.2    Bulmer, G.S.3
  • 18
    • 0018743356 scopus 로고
    • Kinetics of lymphocyte transformation in mice immunized with viable avirulent forms of Cryptococcus neoformans
    • Fromtling RA, Blackstock R, Hall NK, Bulmer GS, (1979) Kinetics of lymphocyte transformation in mice immunized with viable avirulent forms of Cryptococcus neoformans. Infect Immun 24: 449-453.
    • (1979) Infect Immun , vol.24 , pp. 449-453
    • Fromtling, R.A.1    Blackstock, R.2    Hall, N.K.3    Bulmer, G.S.4
  • 19
    • 0018643995 scopus 로고
    • Immunization of mice with an avirulent pseudohyphal form of Cryptococcus neoformans
    • Fromtling RA, Blackstock R, Hall NK, Bulmer GS, (1979) Immunization of mice with an avirulent pseudohyphal form of Cryptococcus neoformans. Mycopathologia 68: 179-181.
    • (1979) Mycopathologia , vol.68 , pp. 179-181
    • Fromtling, R.A.1    Blackstock, R.2    Hall, N.K.3    Bulmer, G.S.4
  • 20
    • 68949100492 scopus 로고
    • Immunization and passive transfer in immunity in murine cryptococcosis
    • In: Kuttin ES, Baum GL, editors, editors
    • Fromtling RA, Blackstock R, Bulmer GS, (1980) Immunization and passive transfer in immunity in murine cryptococcosis. In: Kuttin ES, Baum GL, editors. pp. 122-124 editors. Human and animal mycology: proceedings of the VII Congress of ISHAM. Amsterdam. Princeton; New York: Excerpta Medica. distributors for the USA: Elsevier North-Holland. pp.
    • (1980) , pp. 122-124
    • Fromtling, R.A.1    Blackstock, R.2    Bulmer, G.S.3
  • 21
    • 0016975715 scopus 로고
    • Morphogenesis of Filobasidiella neoformans, the sexual state of Cryptococcus neoformans
    • Kwon-Chung KJ, (1976) Morphogenesis of Filobasidiella neoformans, the sexual state of Cryptococcus neoformans. Mycologia 68: 821-833.
    • (1976) Mycologia , vol.68 , pp. 821-833
    • Kwon-Chung, K.J.1
  • 23
    • 77958174704 scopus 로고    scopus 로고
    • Evolution of eukaryotic microbial pathogens via covert sexual reproduction
    • Heitman J, (2010) Evolution of eukaryotic microbial pathogens via covert sexual reproduction. Cell Host Microbe 8: 86-99.
    • (2010) Cell Host Microbe , vol.8 , pp. 86-99
    • Heitman, J.1
  • 25
    • 78649920711 scopus 로고    scopus 로고
    • Ste50 adaptor protein governs sexual differentiation of Cryptococcus neoformans via the pheromone-response MAPK signaling pathway
    • Jung KW, Kim SY, Okagaki LH, Nielsen K, Bahn YS, (2011) Ste50 adaptor protein governs sexual differentiation of Cryptococcus neoformans via the pheromone-response MAPK signaling pathway. Fungal Genet Biol 48: 154-165.
    • (2011) Fungal Genet Biol , vol.48 , pp. 154-165
    • Jung, K.W.1    Kim, S.Y.2    Okagaki, L.H.3    Nielsen, K.4    Bahn, Y.S.5
  • 26
    • 0037487244 scopus 로고    scopus 로고
    • A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans
    • Davidson RC, Nichols CB, Cox GM, Perfect JR, Heitman J, (2003) A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans. Mol Microbiol 49: 469-485.
    • (2003) Mol Microbiol , vol.49 , pp. 469-485
    • Davidson, R.C.1    Nichols, C.B.2    Cox, G.M.3    Perfect, J.R.4    Heitman, J.5
  • 27
    • 2542587112 scopus 로고    scopus 로고
    • The alpha-specific cell identity factor Sxi1alpha is not required for virulence of Cryptococcus neoformans
    • Hull CM, Cox GM, Heitman J, (2004) The alpha-specific cell identity factor Sxi1alpha is not required for virulence of Cryptococcus neoformans. Infect Immun 72: 3643-3645.
    • (2004) Infect Immun , vol.72 , pp. 3643-3645
    • Hull, C.M.1    Cox, G.M.2    Heitman, J.3
  • 28
    • 77953192777 scopus 로고    scopus 로고
    • Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite- and same-sex mating in Cryptococcus neoformans
    • Lin X, Jackson JC, Feretzaki M, Xue C, Heitman J, (2010) Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite- and same-sex mating in Cryptococcus neoformans. PLoS Genet 6: e1000953.
    • (2010) PLoS Genet , vol.6
    • Lin, X.1    Jackson, J.C.2    Feretzaki, M.3    Xue, C.4    Heitman, J.5
  • 29
    • 68949105809 scopus 로고    scopus 로고
    • Cryptococcus neoformans: morphogenesis, infection, and evolution
    • Lin X, (2009) Cryptococcus neoformans: morphogenesis, infection, and evolution. Infect Genet Evol 9: 401-416.
    • (2009) Infect Genet Evol , vol.9 , pp. 401-416
    • Lin, X.1
  • 30
    • 13744249299 scopus 로고    scopus 로고
    • A homolog of Ste6, the a-factor transporter in Saccharomyces cerevisiae, is required for mating but not for monokaryotic fruiting in Cryptococcus neoformans
    • Hsueh YP, Shen WC, (2005) A homolog of Ste6, the a-factor transporter in Saccharomyces cerevisiae, is required for mating but not for monokaryotic fruiting in Cryptococcus neoformans. Eukaryot Cell 4: 147-155.
    • (2005) Eukaryot Cell , vol.4 , pp. 147-155
    • Hsueh, Y.P.1    Shen, W.C.2
  • 31
    • 0036616588 scopus 로고    scopus 로고
    • Molecular analysis of CPRalpha, a MATalpha-specific pheromone receptor gene of Cryptococcus neoformans
    • Chung S, Karos M, Chang YC, Lukszo J, Wickes BL, et al. (2002) Molecular analysis of CPRalpha, a MATalpha-specific pheromone receptor gene of Cryptococcus neoformans. Eukaryot Cell 1: 432-439.
    • (2002) Eukaryot Cell , vol.1 , pp. 432-439
    • Chung, S.1    Karos, M.2    Chang, Y.C.3    Lukszo, J.4    Wickes, B.L.5
  • 32
    • 0036615226 scopus 로고    scopus 로고
    • Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans
    • Shen WC, Davidson RC, Cox GM, Heitman J, (2002) Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans. Eukaryot Cell 1: 366-377.
    • (2002) Eukaryot Cell , vol.1 , pp. 366-377
    • Shen, W.C.1    Davidson, R.C.2    Cox, G.M.3    Heitman, J.4
  • 33
    • 17844369955 scopus 로고    scopus 로고
    • Sexual reproduction between partners of the same mating type in Cryptococcus neoformans
    • Lin X, Hull CM, Heitman J, (2005) Sexual reproduction between partners of the same mating type in Cryptococcus neoformans. Nature 434: 1017-1021.
    • (2005) Nature , vol.434 , pp. 1017-1021
    • Lin, X.1    Hull, C.M.2    Heitman, J.3
  • 34
    • 0033986793 scopus 로고    scopus 로고
    • The G-protein beta subunit GPB1 is required for mating and haploid fruiting in Cryptococcus neoformans
    • Wang P, Perfect JR, Heitman J, (2000) The G-protein beta subunit GPB1 is required for mating and haploid fruiting in Cryptococcus neoformans. Mol Cell Biol 20: 352-362.
    • (2000) Mol Cell Biol , vol.20 , pp. 352-362
    • Wang, P.1    Perfect, J.R.2    Heitman, J.3
  • 35
    • 57649240401 scopus 로고    scopus 로고
    • Three galactose inducible promoters for use in C. neoformans var. grubii
    • Ruff JA, Lodge JK, Baker LG, (2009) Three galactose inducible promoters for use in C. neoformans var. grubii. Fungal Genet Biol 46: 9-16.
    • (2009) Fungal Genet Biol , vol.46 , pp. 9-16
    • Ruff, J.A.1    Lodge, J.K.2    Baker, L.G.3
  • 36
    • 4444251972 scopus 로고    scopus 로고
    • An efficiently regulated promoter system for Cryptococcus neoformans utilizing the CTR4 promoter
    • Ory JJ, Griffith CL, Doering TL, (2004) An efficiently regulated promoter system for Cryptococcus neoformans utilizing the CTR4 promoter. Yeast 21: 919-926.
    • (2004) Yeast , vol.21 , pp. 919-926
    • Ory, J.J.1    Griffith, C.L.2    Doering, T.L.3
  • 37
    • 70849098812 scopus 로고    scopus 로고
    • Toggle involving cis-interfering noncoding RNAs controls variegated gene expression in yeast
    • Bumgarner SL, Dowell RD, Grisafi P, Gifford DK, Fink GR, (2009) Toggle involving cis-interfering noncoding RNAs controls variegated gene expression in yeast. Proc Natl Acad Sci U S A 106: 18321-18326.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 18321-18326
    • Bumgarner, S.L.1    Dowell, R.D.2    Grisafi, P.3    Gifford, D.K.4    Fink, G.R.5
  • 38
    • 1342346635 scopus 로고    scopus 로고
    • Capsule shields the function of short bacterial adhesins
    • Schembri MA, Dalsgaard D, Klemm P, (2004) Capsule shields the function of short bacterial adhesins. J Bacteriol 186: 1249-1257.
    • (2004) J Bacteriol , vol.186 , pp. 1249-1257
    • Schembri, M.A.1    Dalsgaard, D.2    Klemm, P.3
  • 39
    • 77953542627 scopus 로고    scopus 로고
    • Analysis of flocculins in Ashbya gossypii reveals FIG2 regulation by TEC1
    • Grunler A, Walther A, Lammel J, Wendland J, (2010) Analysis of flocculins in Ashbya gossypii reveals FIG2 regulation by TEC1. Fungal Genet Biol 47: 619-628.
    • (2010) Fungal Genet Biol , vol.47 , pp. 619-628
    • Grunler, A.1    Walther, A.2    Lammel, J.3    Wendland, J.4
  • 40
    • 33749564710 scopus 로고    scopus 로고
    • Characterization of a flocculation-like phenotype in Cryptococcus neoformans and its effects on pathogenesis
    • Li L, Zaragoza O, Casadevall A, Fries BC, (2006) Characterization of a flocculation-like phenotype in Cryptococcus neoformans and its effects on pathogenesis. Cell Microbiol 8: 1730-1739.
    • (2006) Cell Microbiol , vol.8 , pp. 1730-1739
    • Li, L.1    Zaragoza, O.2    Casadevall, A.3    Fries, B.C.4
  • 41
    • 23344445944 scopus 로고    scopus 로고
    • Identification and characterization of an SKN7 homologue in Cryptococcus neoformans
    • Wormley FL Jr, Heinrich G, Miller JL, Perfect JR, Cox GM, (2005) Identification and characterization of an SKN7 homologue in Cryptococcus neoformans. Infect Immun 73: 5022-5030.
    • (2005) Infect Immun , vol.73 , pp. 5022-5030
    • Wormley Jr., F.L.1    Heinrich, G.2    Miller, J.L.3    Perfect, J.R.4    Cox, G.M.5
  • 42
    • 77953192777 scopus 로고    scopus 로고
    • Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite and same-sex mating in Cryptococcus neoformans
    • Lin X, Jackson JC, Feretzaki M, Xue C, Heitman J, (2010) Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite and same-sex mating in Cryptococcus neoformans. PLoS Genet 6: e1000953.
    • (2010) PLoS Genet , vol.6
    • Lin, X.1    Jackson, J.C.2    Feretzaki, M.3    Xue, C.4    Heitman, J.5
  • 43
    • 0034677952 scopus 로고    scopus 로고
    • Cell wall biogenesis of Blastomyces dermatitidis. Evidence for a novel mechanism of cell surface localization of a virulence-associated adhesin via extracellular release and reassociation with cell wall chitin
    • Brandhorst T, Klein B, (2000) Cell wall biogenesis of Blastomyces dermatitidis. Evidence for a novel mechanism of cell surface localization of a virulence-associated adhesin via extracellular release and reassociation with cell wall chitin. J Biol Chem 275: 7925-7934.
    • (2000) J Biol Chem , vol.275 , pp. 7925-7934
    • Brandhorst, T.1    Klein, B.2
  • 44
    • 18044392276 scopus 로고    scopus 로고
    • Surface localization of the Yps3p protein of Histoplasma capsulatum
    • Bohse ML, Woods JP, (2005) Surface localization of the Yps3p protein of Histoplasma capsulatum. Eukaryot Cell 4: 685-693.
    • (2005) Eukaryot Cell , vol.4 , pp. 685-693
    • Bohse, M.L.1    Woods, J.P.2
  • 45
    • 0035793383 scopus 로고    scopus 로고
    • Bakers' yeast, a model for fungal biofilm formation
    • Reynolds TB, Fink GR, (2001) Bakers' yeast, a model for fungal biofilm formation. Science 291: 878-881.
    • (2001) Science , vol.291 , pp. 878-881
    • Reynolds, T.B.1    Fink, G.R.2
  • 46
    • 76749150995 scopus 로고    scopus 로고
    • Environmental and genetic determinants of colony morphology in yeast
    • Granek JA, Magwene PM, (2010) Environmental and genetic determinants of colony morphology in yeast. PLoS Genet 6: e1000823.
    • (2010) PLoS Genet , vol.6
    • Granek, J.A.1    Magwene, P.M.2
  • 47
    • 4644232332 scopus 로고    scopus 로고
    • PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans
    • Nichols CB, Fraser JA, Heitman J, (2004) PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans. Mol Biol Cell 15: 4476-4489.
    • (2004) Mol Biol Cell , vol.15 , pp. 4476-4489
    • Nichols, C.B.1    Fraser, J.A.2    Heitman, J.3
  • 49
    • 79956151029 scopus 로고    scopus 로고
    • Fungal mating pheromones: choreographing the dating game
    • Jones SK Jr, Bennett RJ, (2011) Fungal mating pheromones: choreographing the dating game. Fungal Genet Biol 48: 668-676.
    • (2011) Fungal Genet Biol , vol.48 , pp. 668-676
    • Jones Jr., S.K.1    Bennett, R.J.2
  • 50
    • 0026324385 scopus 로고
    • Infection due to Cryptococcus neoformans of unusual morphology in a patient with AIDS
    • Anandi V, Babu PG, John TJ, (1991) Infection due to Cryptococcus neoformans of unusual morphology in a patient with AIDS. Mycoses 34: 377-379.
    • (1991) Mycoses , vol.34 , pp. 377-379
    • Anandi, V.1    Babu, P.G.2    John, T.J.3
  • 51
    • 0033952723 scopus 로고    scopus 로고
    • Temperature-sensitive strain of Cryptococcus neoformans producing hyphal elements in a feline nasal granuloma
    • Bemis DA, Krahwinkel DJ, Bowman LA, Mondon P, Kwon-Chung KJ, (2000) Temperature-sensitive strain of Cryptococcus neoformans producing hyphal elements in a feline nasal granuloma. J Clin Microbiol 38: 926-928.
    • (2000) J Clin Microbiol , vol.38 , pp. 926-928
    • Bemis, D.A.1    Krahwinkel, D.J.2    Bowman, L.A.3    Mondon, P.4    Kwon-Chung, K.J.5
  • 52
    • 0014977109 scopus 로고
    • Meningoencephalitis due to hyphae-forming Cryptococcus neoformans
    • Freed ER, Duma RJ, Shadomy HJ, Utz JP, (1971) Meningoencephalitis due to hyphae-forming Cryptococcus neoformans. Am J Clin Pathol 55: 30-33.
    • (1971) Am J Clin Pathol , vol.55 , pp. 30-33
    • Freed, E.R.1    Duma, R.J.2    Shadomy, H.J.3    Utz, J.P.4
  • 53
    • 0029875172 scopus 로고    scopus 로고
    • Atypical cytomorphologic appearance of Cryptococcus neoformans: a report of five cases
    • Williamson JD, Silverman JF, Mallak CT, Christie JD, (1996) Atypical cytomorphologic appearance of Cryptococcus neoformans: a report of five cases. Acta Cytol 40: 363-370.
    • (1996) Acta Cytol , vol.40 , pp. 363-370
    • Williamson, J.D.1    Silverman, J.F.2    Mallak, C.T.3    Christie, J.D.4
  • 54
    • 34548478560 scopus 로고    scopus 로고
    • G protein signaling governing cell fate decisions involves opposing Galpha subunits in Cryptococcus neoformans
    • Hsueh YP, Xue C, Heitman J, (2007) G protein signaling governing cell fate decisions involves opposing Galpha subunits in Cryptococcus neoformans. Mol Biol Cell 18: 3237-3249.
    • (2007) Mol Biol Cell , vol.18 , pp. 3237-3249
    • Hsueh, Y.P.1    Xue, C.2    Heitman, J.3
  • 55
    • 52949114243 scopus 로고    scopus 로고
    • Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans
    • Liu OW, Chun CD, Chow ED, Chen C, Madhani HD, et al. (2008) Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans. Cell 135: 174-188.
    • (2008) Cell , vol.135 , pp. 174-188
    • Liu, O.W.1    Chun, C.D.2    Chow, E.D.3    Chen, C.4    Madhani, H.D.5
  • 56
    • 14644423252 scopus 로고    scopus 로고
    • Evaluation of host immune responses to pulmonary cryptococcosis using a temperature-sensitive C. neoformans calcineurin A mutant strain
    • Wormley FL Jr, Cox GM, Perfect JR, (2005) Evaluation of host immune responses to pulmonary cryptococcosis using a temperature-sensitive C. neoformans calcineurin A mutant strain. Microb Pathog 38: 113-123.
    • (2005) Microb Pathog , vol.38 , pp. 113-123
    • Wormley Jr., F.L.1    Cox, G.M.2    Perfect, J.R.3
  • 57
    • 34247495564 scopus 로고    scopus 로고
    • Systematic capsule gene disruption reveals the central role of galactose metabolism on Cryptococcus neoformans virulence
    • Moyrand F, Fontaine T, Janbon G, (2007) Systematic capsule gene disruption reveals the central role of galactose metabolism on Cryptococcus neoformans virulence. Mol Microbiol 64: 771-781.
    • (2007) Mol Microbiol , vol.64 , pp. 771-781
    • Moyrand, F.1    Fontaine, T.2    Janbon, G.3
  • 59
    • 46449107725 scopus 로고    scopus 로고
    • Impact of mating type, serotype, and ploidy on the virulence of Cryptococcus neoformans
    • Lin X, Nielsen K, Patel S, Heitman J, (2008) Impact of mating type, serotype, and ploidy on the virulence of Cryptococcus neoformans. Infect Immun 76: 2923-2938.
    • (2008) Infect Immun , vol.76 , pp. 2923-2938
    • Lin, X.1    Nielsen, K.2    Patel, S.3    Heitman, J.4
  • 61
    • 31944437746 scopus 로고    scopus 로고
    • G protein-coupled receptor Gpr4 senses amino acids and activates the cAMP-PKA pathway in Cryptococcus neoformans
    • Xue C, Bahn YS, Cox GM, Heitman J, (2006) G protein-coupled receptor Gpr4 senses amino acids and activates the cAMP-PKA pathway in Cryptococcus neoformans. Mol Biol Cell 17: 667-679.
    • (2006) Mol Biol Cell , vol.17 , pp. 667-679
    • Xue, C.1    Bahn, Y.S.2    Cox, G.M.3    Heitman, J.4
  • 62
    • 34948907855 scopus 로고    scopus 로고
    • Fatty acid synthesis is essential for survival of Cryptococcus neoformans and a potential fungicidal target
    • Chayakulkeeree M, Rude TH, Toffaletti DL, Perfect JR, (2007) Fatty acid synthesis is essential for survival of Cryptococcus neoformans and a potential fungicidal target. Antimicrob Agents Chemother 51: 3537-3545.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3537-3545
    • Chayakulkeeree, M.1    Rude, T.H.2    Toffaletti, D.L.3    Perfect, J.R.4
  • 63
    • 75149119287 scopus 로고    scopus 로고
    • Septins enforce morphogenetic events during sexual reproduction and contribute to virulence of Cryptococcus neoformans
    • Kozubowski L, Heitman J, (2010) Septins enforce morphogenetic events during sexual reproduction and contribute to virulence of Cryptococcus neoformans. Mol Microbiol 75: 658-675.
    • (2010) Mol Microbiol , vol.75 , pp. 658-675
    • Kozubowski, L.1    Heitman, J.2
  • 64
    • 79957955956 scopus 로고    scopus 로고
    • The F-box protein Fbp1 regulates sexual reproduction and virulence in Cryptococcus neoformans
    • Liu TB, Wang Y, Stukes S, Chen Q, Casadevall A, et al. (2011) The F-box protein Fbp1 regulates sexual reproduction and virulence in Cryptococcus neoformans. Eukaryot Cell 10: 791-802.
    • (2011) Eukaryot Cell , vol.10 , pp. 791-802
    • Liu, T.B.1    Wang, Y.2    Stukes, S.3    Chen, Q.4    Casadevall, A.5
  • 65
    • 67349250479 scopus 로고    scopus 로고
    • Biofilm formation by Cryptococcus neoformans under distinct environmental conditions
    • Ravi S, Pierce C, Witt C, Wormley FL Jr, (2009) Biofilm formation by Cryptococcus neoformans under distinct environmental conditions. Mycopathologia 167: 307-314.
    • (2009) Mycopathologia , vol.167 , pp. 307-314
    • Ravi, S.1    Pierce, C.2    Witt, C.3    Wormley Jr., F.L.4
  • 67
    • 35948978169 scopus 로고    scopus 로고
    • aADa hybrids of Cryptococcus neoformans: Evidence of same sex mating in nature and hybrid fitness
    • Lin X, Litvintseva A, Nielsen K, Patel S, Kapadia Z, et al. (2007) aADa hybrids of Cryptococcus neoformans: Evidence of same sex mating in nature and hybrid fitness. PLoS Genet 3: e186.
    • (2007) PLoS Genet , vol.3
    • Lin, X.1    Litvintseva, A.2    Nielsen, K.3    Patel, S.4    Kapadia, Z.5
  • 68
    • 58849131459 scopus 로고    scopus 로고
    • Expression levels of a filament-specific transcriptional regulator are sufficient to determine Candida albicans morphology and virulence
    • Carlisle PL, Banerjee M, Lazzell A, Monteagudo C, Lopez-Ribot JL, et al. (2009) Expression levels of a filament-specific transcriptional regulator are sufficient to determine Candida albicans morphology and virulence. Proc Natl Acad Sci U S A 106: 599-604.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 599-604
    • Carlisle, P.L.1    Banerjee, M.2    Lazzell, A.3    Monteagudo, C.4    Lopez-Ribot, J.L.5
  • 69
    • 67651219153 scopus 로고    scopus 로고
    • Most environmental isolates of Cryptococcus neoformans var. grubii (Serotype A) are not lethal for mice
    • Litvintseva AP, Mitchell TG, (2009) Most environmental isolates of Cryptococcus neoformans var. grubii (Serotype A) are not lethal for mice. Infect Immun 77: 3188-3195.
    • (2009) Infect Immun , vol.77 , pp. 3188-3195
    • Litvintseva, A.P.1    Mitchell, T.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.