Role of the outer pore domain in transient receptor potential vanilloid 1 dynamic permeability to large cations

Journal of Biological Chemistry

Volumn 290, Issue 9, 2015, Pages 5707-5724

  Munns, Clare H ^a   Chung, Man Kyo ^c   Sanchez, Yuly E ^b,d,e   Amzel, L Mario ^b   Caterina, Michael J ^a,b  

^a Neuroscience Branch   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^d UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^e PONTIFICIA UNIVERSIDAD JAVERIANA   (Colombia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

AGONIST-DEPENDENT MANNER; DYNAMIC PERMEABILITY; FLUORESCENT DYES; N-METHYL-D-GLUCAMINE; PLAUSIBLE MECHANISMS; SELECTIVITY FILTER; SIDE-CHAIN INTERACTIONS; TRANSIENT RECEPTOR POTENTIAL VANILLOID;

POSITIVE IONS;

CAPSAICIN; FLUORESCENT DYE; MEGLUMINE; RESINIFERATOXIN; SODIUM ION; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; BENZOXAZOLE DERIVATIVE; CATION; DITERPENE; QUINOLINE DERIVATIVE; TRPV1 PROTEIN, MOUSE; TRPV1 PROTEIN, RAT; VANILLOID RECEPTOR; YO-PRO 1;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONFORMATION; CONTROLLED STUDY; DYNAMICS; FILTER; GAIN OF FUNCTION MUTATION; HUMAN; HUMAN CELL; ION PERMEABILITY; LOSS OF FUNCTION MUTATION; MOUSE; MUTANT; MUTATIONAL ANALYSIS; NONHUMAN; PARTICLE SIZE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; QUANTITATIVE TRAIT LOCUS; RAT; SITE DIRECTED MUTAGENESIS; ANIMAL; CHANNEL GATING; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; MISSENSE MUTATION; PERMEABILITY; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BENZOXAZOLES; BIOLOGICAL TRANSPORT; CAPSAICIN; CATIONS; DITERPENES; FLUORESCENT DYES; HEK293 CELLS; HUMANS; ION CHANNEL GATING; MEGLUMINE; MICE; MODELS, MOLECULAR; MUTATION, MISSENSE; PERMEABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; QUINOLINIUM COMPOUNDS; RATS; TRPV CATION CHANNELS;

EID: 84923781868     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.597435     Document Type: Article

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