Recruitment of the adaptor protein Nck to PECAM-1 couples oxidative stress to canonical NF-kB signaling and inflammation

Science Signaling

Volumn 8, Issue 365, 2015, Pages

  Chen, Jie ^a   Leskov, Igor L ^a   Yurdagul, Arif ^a   Thiel, Bonnie ^b   Kevil, Christopher G ^a   Stokes, Karen Y ^a   Orr, A Wayne ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ANTIOXIDANT; CD31 ANTIGEN; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; NCK PROTEIN; P21 ACTIVATED KINASE; PROTEIN TYROSINE KINASE; TYROSINE; VASCULAR CELL ADHESION MOLECULE 1; ONCOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; ATTENUATION; CELL DAMAGE; CELL HYPOXIA; CELL MIGRATION; CONTROLLED STUDY; CREMASTER MUSCLE; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LEUKOCYTE; LEUKOCYTE ADHERENCE; LOW DRUG DOSE; MALE; MEDIATOR; MOUSE; MUSCLE ISCHEMIA; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; REOXYGENATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; ANIMAL; HEK293 CELL LINE; METABOLISM; SKELETAL MUSCLE; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, CD31; CELL LINE, TUMOR; HEK293 CELLS; HUMANS; INFLAMMATION; MICE; MUSCLE, SKELETAL; NF-KAPPA B; ONCOGENE PROTEINS; OXIDATIVE STRESS; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

EID: 84923690676     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005648     Document Type: Article

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