메뉴 건너뛰기




Volumn 126, Issue 7, 2013, Pages 1637-1649

Nck enables directional cell migration through the coordination of polarized membrane protrusion with adhesion dynamics

Author keywords

Actin cytoskeleton; Cell adhesion; Cell polarity; Directional migration; Nck

Indexed keywords

FIBRONECTIN; MYOSIN II; NCK PROTEIN; PROTEIN CDC42; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; VERY LATE ACTIVATION ANTIGEN 5;

EID: 84877950657     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.119610     Document Type: Article
Times cited : (40)

References (81)
  • 2
    • 34249689753 scopus 로고    scopus 로고
    • Molecular regulation of angiogenesis and lymphangiogenesis
    • Adams, R. H. and Alitalo, K. (2007). Molecular regulation of angiogenesis and lymphangiogenesis. Nat. Rev. Mol. Cell Biol. 8, 464-47
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 464-547
    • Adams, R.H.1    Alitalo, K.2
  • 3
    • 55049083860 scopus 로고    scopus 로고
    • A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors
    • Antoku, S., Saksela, K., Rivera, G. M. and Mayer, B. J. (2008). A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors. J. Cell Sci. 121, 3071-308
    • (2008) J. Cell Sci. , vol.121 , pp. 3071-3308
    • Antoku, S.1    Saksela, K.2    Rivera, G.M.3    Mayer, B.J.4
  • 4
    • 73949099966 scopus 로고    scopus 로고
    • Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors
    • Aoki, K. and Matsuda, M. (2009). Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors. Nat. Protoc. 4, 1623-163
    • (2009) Nat. Protoc. , vol.4 , pp. 1623-2163
    • Aoki, K.1    Matsuda, M.2
  • 5
    • 12344272845 scopus 로고    scopus 로고
    • Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton
    • Barda-Saad, M., Braiman, A., Titerence, R., Bunnell, S. C., Barr, V. A. and Samelson, L. E. (2005). Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton. Nat. Immunol. 6, 80-8
    • (2005) Nat. Immunol. , vol.6 , pp. 80-88
    • Barda-Saad, M.1    Braiman, A.2    Titerence, R.3    Bunnell, S.C.4    Barr, V.A.5    Samelson, L.E.6
  • 7
    • 79960334368 scopus 로고    scopus 로고
    • Highresolution quantification of focal adhesion spatiotemporal dynamics in living cells
    • Berginski, M. E., Vitriol, E. A., Hahn, K. M. and Gomez, S. M. (2011). Highresolution quantification of focal adhesion spatiotemporal dynamics in living cells. PLoS ONE 6, e2202
    • (2011) PLoS ONE , vol.6
    • Berginski, M.E.1    Vitriol, E.A.2    Hahn, K.M.3    Gomez, S.M.4
  • 8
    • 0038383014 scopus 로고    scopus 로고
    • The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network
    • Bladt, F., Aippersbach, E., Gelkop, S., Strasser, G. A., Nash, P., Tafuri, A., Gertler, F. B. and Pawson, T. (2003). The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network. Mol. Cell. Biol. 23, 4586-459
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 4586-5459
    • Bladt, F.1    Aippersbach, E.2    Gelkop, S.3    Strasser, G.A.4    Nash, P.5    Tafuri, A.6    Gertler, F.B.7    Pawson, T.8
  • 9
    • 0038554077 scopus 로고    scopus 로고
    • Biology of the p21-activated kinases
    • Bokoch, G. M. (2003). Biology of the p21-activated kinases. Annu. Rev. Biochem. 72, 743-78
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 743-778
    • Bokoch, G.M.1
  • 10
    • 24344508125 scopus 로고    scopus 로고
    • Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness
    • Brown, M. C., Cary, L. A., Jamieson, J. S., Cooper, J. A. and Turner, C. E. (2005). Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness. Mol. Biol. Cell 16, 4316-432
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4316-4432
    • Brown, M.C.1    Cary, L.A.2    Jamieson, J.S.3    Cooper, J.A.4    Turner, C.E.5
  • 11
    • 0036015163 scopus 로고    scopus 로고
    • The Nck family of adapter proteins: regulators of actin cytoskeleton
    • Buday, L., Wunderlich, L. and Tamás, P. (2002). The Nck family of adapter proteins: regulators of actin cytoskeleton. Cell. Signal. 14, 723-73
    • (2002) Cell. Signal. , vol.14 , pp. 723-773
    • Buday, L.1    Wunderlich, L.2    Tamás, P.3
  • 12
    • 0842309767 scopus 로고    scopus 로고
    • Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly
    • Campellone, K. G., Rankin, S., Pawson, T., Kirschner, M. W., Tipper, D. J. and Leong, J. M. (2004). Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly. J. Cell Biol. 164, 407-41
    • (2004) J. Cell Biol. , vol.164 , pp. 407-441
    • Campellone, K.G.1    Rankin, S.2    Pawson, T.3    Kirschner, M.W.4    Tipper, D.J.5    Leong, J.M.6
  • 13
    • 84861520898 scopus 로고    scopus 로고
    • Spatial regulation of receptor tyrosine kinases in development and cancer
    • Casaletto, J. B. and McClatchey, A. I. (2012). Spatial regulation of receptor tyrosine kinases in development and cancer. Nat. Rev. Cancer 12, 387-40
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 387-440
    • Casaletto, J.B.1    McClatchey, A.I.2
  • 14
    • 51049104617 scopus 로고    scopus 로고
    • Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner
    • Choi, C. K., Vicente-Manzanares, M., Zareno, J., Whitmore, L. A., Mogilner, A. and Horwitz, A. R. (2008). Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner. Nat. Cell Biol. 10, 1039-105
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1039-1105
    • Choi, C.K.1    Vicente-Manzanares, M.2    Zareno, J.3    Whitmore, L.A.4    Mogilner, A.5    Horwitz, A.R.6
  • 15
    • 84869143244 scopus 로고    scopus 로고
    • Nck and Cdc42 co-operate to recruit N-WASP to promote FccR-mediated phagocytosis
    • Dart, A. E., Donnelly, S. K., Holden, D. W., Way, M. and Caron, E. (2012). Nck and Cdc42 co-operate to recruit N-WASP to promote FccR-mediated phagocytosis. J. Cell Sci. 125, 2825-283
    • (2012) J. Cell Sci. , vol.125 , pp. 2825-3283
    • Dart, A.E.1    Donnelly, S.K.2    Holden, D.W.3    Way, M.4    Caron, E.5
  • 18
    • 75149162463 scopus 로고    scopus 로고
    • Nck- and N-WASP-dependent actin-based motility is conserved in divergent vertebrate poxviruses
    • Dodding, M. P. and Way, M. (2009). Nck- and N-WASP-dependent actin-based motility is conserved in divergent vertebrate poxviruses. Cell Host Microbe 6, 536-55
    • (2009) Cell Host Microbe , vol.6 , pp. 536-555
    • Dodding, M.P.1    Way, M.2
  • 19
    • 0037102301 scopus 로고    scopus 로고
    • Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
    • Eden, S., Rohatgi, R., Podtelejnikov, A. V., Mann, M. and Kirschner, M. W. (2002). Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck. Nature 418, 790-79
    • (2002) Nature , vol.418 , pp. 790-879
    • Eden, S.1    Rohatgi, R.2    Podtelejnikov, A.V.3    Mann, M.4    Kirschner, M.W.5
  • 20
    • 0035943401 scopus 로고    scopus 로고
    • Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta
    • Etienne-Manneville, S. and Hall, A. (2001). Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell 106, 489-49
    • (2001) Cell , vol.106 , pp. 489-549
    • Etienne-Manneville, S.1    Hall, A.2
  • 21
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville, S. and Hall, A. (2002). Rho GTPases in cell biology. Nature 420, 629-63
    • (2002) Nature , vol.420 , pp. 629-663
    • Etienne-Manneville, S.1    Hall, A.2
  • 22
    • 75749146306 scopus 로고    scopus 로고
    • Plasticity of cell migration: a multiscale tuning model
    • Friedl, P. and Wolf, K. (2010). Plasticity of cell migration: a multiscale tuning model. J. Cell Biol. 188, 11-1
    • (2010) J. Cell Biol. , vol.188 , pp. 11-21
    • Friedl, P.1    Wolf, K.2
  • 23
    • 77955809108 scopus 로고    scopus 로고
    • Cas utilizes Nck2 to activate Cdc42 and regulate cell polarization during cell migration in response to wound healing
    • Funasaka, K., Ito, S., Hasegawa, H., Goldberg, G. S., Hirooka, Y., Goto, H., Hamaguchi, M. and Senga, T. (2010). Cas utilizes Nck2 to activate Cdc42 and regulate cell polarization during cell migration in response to wound healing. FEBS J. 277, 3502-351
    • (2010) FEBS J , vol.277 , pp. 3502-4351
    • Funasaka, K.1    Ito, S.2    Hasegawa, H.3    Goldberg, G.S.4    Hirooka, Y.5    Goto, H.6    Hamaguchi, M.7    Senga, T.8
  • 24
    • 0029830139 scopus 로고    scopus 로고
    • The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1
    • Galisteo, M. L., Chernoff, J., Su, Y. C., Skolnik, E. Y. and Schlessinger, J. (1996). The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1. J. Biol. Chem. 271, 20997-2100
    • (1996) J. Biol. Chem. , vol.271 , pp. 20997-22100
    • Galisteo, M.L.1    Chernoff, J.2    Su, Y.C.3    Skolnik, E.Y.4    Schlessinger, J.5
  • 26
  • 28
    • 34548243624 scopus 로고    scopus 로고
    • Nckbeta adapter controls neuritogenesis by maintaining the cellular paxillin level
    • Guan, S., Chen, M., Woodley, D. and Li, W. (2007). Nckbeta adapter controls neuritogenesis by maintaining the cellular paxillin level. Mol. Cell. Biol. 27, 6001-601
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 6001-6601
    • Guan, S.1    Chen, M.2    Woodley, D.3    Li, W.4
  • 29
    • 67651112122 scopus 로고    scopus 로고
    • Noncompensating roles between Nckalpha and Nckbeta in PDGF-BB signaling to promote human dermal fibroblast migration
    • Guan, S., Fan, J., Han, A., Chen, M., Woodley, D. T. and Li, W. (2009). Noncompensating roles between Nckalpha and Nckbeta in PDGF-BB signaling to promote human dermal fibroblast migration. J. Invest. Dermatol. 129, 1909-192
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 1909-2192
    • Guan, S.1    Fan, J.2    Han, A.3    Chen, M.4    Woodley, D.T.5    Li, W.6
  • 30
    • 0033603826 scopus 로고    scopus 로고
    • Quantifying lamella dynamics of cultured cells by SACED, a new computer-assisted motion analysis
    • Hinz, B., Alt, W., Johnen, C., Herzog, V. and Kaiser, H. W. (1999). Quantifying lamella dynamics of cultured cells by SACED, a new computer-assisted motion analysis. Exp. Cell Res. 251, 234-24
    • (1999) Exp. Cell Res. , vol.251 , pp. 234-324
    • Hinz, B.1    Alt, W.2    Johnen, C.3    Herzog, V.4    Kaiser, H.W.5
  • 31
    • 67650080520 scopus 로고    scopus 로고
    • Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1
    • Hu, T., Shi, G., Larose, L., Rivera, G. M., Mayer, B. J. and Zhou, R. (2009). Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1. Biochemistry 48, 6369-637
    • (2009) Biochemistry , vol.48 , pp. 6369-6637
    • Hu, T.1    Shi, G.2    Larose, L.3    Rivera, G.M.4    Mayer, B.J.5    Zhou, R.6
  • 35
    • 79953303384 scopus 로고    scopus 로고
    • Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for b-Pix in negative regulation of focal adhesion maturation
    • Kuo, J. C., Han, X., Hsiao, C. T., Yates, J. R., 3rd and Waterman, C. M. (2011). Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for b-Pix in negative regulation of focal adhesion maturation. Nat. Cell Biol. 13, 383-39
    • (2011) Nat. Cell Biol. , vol.13 , pp. 383-439
    • Kuo, J.C.1    Han, X.2    Hsiao, C.T.3    Yates III, J.R.4    Waterman, C.M.5
  • 36
    • 33845953426 scopus 로고    scopus 로고
    • Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/ p38 activation and endothelial cell migration in response to VEGF
    • Lamalice, L., Houle, F. and Huot, J. (2006). Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/ p38 activation and endothelial cell migration in response to VEGF. J. Biol. Chem. 281, 34009-3402
    • (2006) J. Biol. Chem. , vol.281 , pp. 34009-43402
    • Lamalice, L.1    Houle, F.2    Huot, J.3
  • 37
    • 65649119024 scopus 로고    scopus 로고
    • Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion
    • Lapetina, S., Mader, C. C., Machida, K., Mayer, B. J. and Koleske, A. J. (2009). Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion. J. Cell Biol. 185, 503-51
    • (2009) J. Cell Biol. , vol.185 , pp. 503-551
    • Lapetina, S.1    Mader, C.C.2    Machida, K.3    Mayer, B.J.4    Koleske, A.J.5
  • 38
    • 0030045346 scopus 로고    scopus 로고
    • Cell migration: a physically integrated molecular process
    • Lauffenburger, D. A. and Horwitz, A. F. (1996). Cell migration: a physically integrated molecular process. Cell 84, 359-36
    • (1996) Cell , vol.84 , pp. 359-436
    • Lauffenburger, D.A.1    Horwitz, A.F.2
  • 39
    • 70449112591 scopus 로고    scopus 로고
    • Activation of the WAVE complex by coincident signals controls actin assembly
    • Lebensohn, A. M. and Kirschner, M. W. (2009). Activation of the WAVE complex by coincident signals controls actin assembly. Mol. Cell 36, 512-52
    • (2009) Mol. Cell , vol.36 , pp. 512-552
    • Lebensohn, A.M.1    Kirschner, M.W.2
  • 40
    • 33645829585 scopus 로고    scopus 로고
    • The adaptor protein Nck interacts with Fas ligand: Guiding the death factor to the cytotoxic immunological synapse
    • Lettau, M., Qian, J., Linkermann, A., Latreille, M., Larose, L., Kabelitz, D. and Janssen, O. (2006). The adaptor protein Nck interacts with Fas ligand: Guiding the death factor to the cytotoxic immunological synapse. Proc. Natl. Acad. Sci. USA 103, 5911-591
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 5911-6591
    • Lettau, M.1    Qian, J.2    Linkermann, A.3    Latreille, M.4    Larose, L.5    Kabelitz, D.6    Janssen, O.7
  • 41
    • 84877990371 scopus 로고    scopus 로고
    • Nck adapter proteins: functional versatility in T cells
    • Lettau, M., Pieper, J. and Janssen, O. (2009). Nck adapter proteins: functional versatility in T cells. Cell Commun. Signal. 7
    • (2009) Cell Commun. Signal. , pp. 7
    • Lettau, M.1    Pieper, J.2    Janssen, O.3
  • 42
    • 0035473460 scopus 로고    scopus 로고
    • Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton
    • Li, W., Fan, J. and Woodley, D. T. (2001). Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton. Oncogene 20, 6403-641
    • (2001) Oncogene , vol.20 , pp. 6403-6641
    • Li, W.1    Fan, J.2    Woodley, D.T.3
  • 43
    • 77956872916 scopus 로고    scopus 로고
    • Extracellular matrix effect on RhoA signaling modulation in vascular smooth muscle cells
    • Lim, S. M., Kreipe, B. A., Trzeciakowski, J., Dangott, L. and Trache, A. (2010). Extracellular matrix effect on RhoA signaling modulation in vascular smooth muscle cells. Exp. Cell Res. 316, 2833-284
    • (2010) Exp. Cell Res. , vol.316 , pp. 2833-3284
    • Lim, S.M.1    Kreipe, B.A.2    Trzeciakowski, J.3    Dangott, L.4    Trache, A.5
  • 44
    • 84874402776 scopus 로고    scopus 로고
    • RhoA-induced cytoskeletal tension controls adaptive cellular remodeling to mechanical signaling
    • Lim, S. M., Trzeciakowski, J. P., Sreenivasappa, H., Dangott, L. J. and Trache, A. (2012). RhoA-induced cytoskeletal tension controls adaptive cellular remodeling to mechanical signaling. Integr Biol. (Camb) 4, 615-62
    • (2012) Integr Biol. (Camb) , vol.4 , pp. 615-662
    • Lim, S.M.1    Trzeciakowski, J.P.2    Sreenivasappa, H.3    Dangott, L.J.4    Trache, A.5
  • 45
    • 0031080595 scopus 로고    scopus 로고
    • Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck
    • Lu, W., Katz, S., Gupta, R. and Mayer, B. J. (1997). Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck. Curr. Biol. 7, 85-9
    • (1997) Curr. Biol. , vol.7 , pp. 85-89
    • Lu, W.1    Katz, S.2    Gupta, R.3    Mayer, B.J.4
  • 47
    • 12844283323 scopus 로고    scopus 로고
    • The SH2 domain: versatile signaling module and pharmaceutical target
    • Machida, K. and Mayer, B. J. (2005). The SH2 domain: versatile signaling module and pharmaceutical target. Biochim. Biophys. Acta 1747, 1-2
    • (2005) Biochim. Biophys. Acta , vol.1747 , pp. 1-2
    • Machida, K.1    Mayer, B.J.2
  • 49
    • 77951238830 scopus 로고    scopus 로고
    • Remodeling epithelial cell organization: transitions between frontrear and apical-basal polarity
    • Nelson, W. J. (2009). Remodeling epithelial cell organization: transitions between frontrear and apical-basal polarity. Cold Spring Harb. Perspect. Biol. 1, a00051
    • (2009) Cold Spring Harb. Perspect. Biol. , vol.1
    • Nelson, W.J.1
  • 51
    • 78149323428 scopus 로고    scopus 로고
    • Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia
    • Oser, M., Mader, C. C., Gil-Henn, H., Magalhaes, M., Bravo-Cordero, J. J., Koleske, A. J. and Condeelis, J. (2010). Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia. J. Cell Sci. 123, 3662-367
    • (2010) J. Cell Sci. , vol.123 , pp. 3662-367
    • Oser, M.1    Mader, C.C.2    Gil-Henn, H.3    Magalhaes, M.4    Bravo-Cordero, J.J.5    Koleske, A.J.6    Condeelis, J.7
  • 52
    • 0035853689 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins
    • Paik, J. H., Chae, S. s., Lee, M. J., Thangada, S. and Hla, T. (2001). Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins. J. Biol. Chem. 276, 11830-1183
    • (2001) J. Biol. Chem. , vol.276 , pp. 11830-1183
    • Paik, J.H.1    Chae, S.2    Lee, s.3    Thangada, M.J.4    Hla, S.T.5
  • 54
    • 0842346438 scopus 로고    scopus 로고
    • Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems
    • Pawson, T. (2004). Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems. Cell 116, 191-20
    • (2004) Cell , vol.116 , pp. 191-20
    • Pawson, T.1
  • 55
    • 68049083547 scopus 로고    scopus 로고
    • Random versus directionally persistent cell migration
    • Petrie, R. J., Doyle, A. D. and Yamada, K. M. (2009). Random versus directionally persistent cell migration. Nat. Rev. Mol. Cell Biol. 10, 538-54
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 538-54
    • Petrie, R.J.1    Doyle, A.D.2    Yamada, K.M.3
  • 56
    • 84858665656 scopus 로고    scopus 로고
    • The adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteria
    • Pils, S., Kopp, K., Peterson, L., Delgado Tascón, J., Nyffenegger-Jann, N. J. and Hauck, C. R. (2012). The adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteria. PLoS ONE 7, e3280
    • (2012) PLoS ONE , vol.7
    • Pils, S.1    Kopp, K.2    Peterson, L.3    Delgado Tascón, J.4    Nyffenegger-Jann, N.J.5    Hauck, C.R.6
  • 57
    • 84855897077 scopus 로고    scopus 로고
    • Historical overview of Rho GTPases
    • Ridley, A. J. (2012). Historical overview of Rho GTPases. Methods Mol. Biol. 827, 3-1
    • (2012) Methods Mol. Biol. , vol.827 , pp. 3-1
    • Ridley, A.J.1
  • 58
    • 0346965734 scopus 로고    scopus 로고
    • Inducible clustering of membrane-targeted SH3 domains of the adaptor protein Nck triggers localized actin polymerization
    • Rivera, G. M., Bricen{ogonek} o, C. A., Takeshima, F., Snapper, S. B. and Mayer, B. J. (2004). Inducible clustering of membrane-targeted SH3 domains of the adaptor protein Nck triggers localized actin polymerization. Curr. Biol. 14, 11-2
    • (2004) Curr. Biol. , vol.14 , pp. 11-2
    • Rivera, G.M.1    Briceno, C.A.2    Takeshima, F.3    Snapper, S.B.4    Mayer, B.J.5
  • 59
    • 33745447261 scopus 로고    scopus 로고
    • Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B
    • Rivera, G. M., Antoku, S., Gelkop, S., Shin, N. Y., Hanks, S. K., Pawson, T. and Mayer, B. J. (2006). Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B. Proc. Natl. Acad. Sci. USA 103, 9536-954
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 9536-954
    • Rivera, G.M.1    Antoku, S.2    Gelkop, S.3    Shin, N.Y.4    Hanks, S.K.5    Pawson, T.6    Mayer, B.J.7
  • 60
    • 70449130430 scopus 로고    scopus 로고
    • A reciprocal interdependence between Nck and PI(4 5)P(2) promotes localized N-WASp-mediated actin polymerization in living cells
    • Rivera, G. M., Vasilescu, D., Papayannopoulos, V., Lim, W. A. and Mayer, B. J. (2009). A reciprocal interdependence between Nck and PI(4,5)P(2) promotes localized N-WASp-mediated actin polymerization in living cells. Mol. Cell 36, 525-53
    • (2009) Mol. Cell , vol.36 , pp. 525-53
    • Rivera, G.M.1    Vasilescu, D.2    Papayannopoulos, V.3    Lim, W.A.4    Mayer, B.J.5
  • 62
    • 57649219412 scopus 로고    scopus 로고
    • Nck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor
    • Ruusala, A., Pawson, T., Heldin, C. H. and Aspenström, P. (2008). Nck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor. J. Biol. Chem. 283, 30034-3004
    • (2008) J. Biol. Chem. , vol.283 , pp. 30034-3004
    • Ruusala, A.1    Pawson, T.2    Heldin, C.H.3    Aspenström, P.4
  • 65
    • 0035933713 scopus 로고    scopus 로고
    • NCK and PAK participate in the signaling pathway by which vascular endothelial growth factor stimulates the assembly of focal adhesions
    • Stoletov, K. V., Ratcliffe, K. E., Spring, S. C. and Terman, B. I. (2001). NCK and PAK participate in the signaling pathway by which vascular endothelial growth factor stimulates the assembly of focal adhesions. J. Biol. Chem. 276, 22748-2275
    • (2001) J. Biol. Chem. , vol.276 , pp. 22748-2275
    • Stoletov, K.V.1    Ratcliffe, K.E.2    Spring, S.C.3    Terman, B.I.4
  • 66
    • 1642635123 scopus 로고    scopus 로고
    • Nck and Crk mediate distinct VEGF-induced signaling pathways that serve overlapping functions in focal adhesion turnover and integrin activation
    • Stoletov, K. V., Gong, C. and Terman, B. I. (2004). Nck and Crk mediate distinct VEGF-induced signaling pathways that serve overlapping functions in focal adhesion turnover and integrin activation. Exp. Cell Res. 295, 258-26
    • (2004) Exp. Cell Res. , vol.295 , pp. 258-26
    • Stoletov, K.V.1    Gong, C.2    Terman, B.I.3
  • 68
    • 0141886295 scopus 로고    scopus 로고
    • Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration
    • Suetsugu, S., Yamazaki, D., Kurisu, S. and Takenawa, T. (2003). Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration. Dev. Cell 5, 595-60
    • (2003) Dev. Cell , vol.5 , pp. 595-60
    • Suetsugu, S.1    Yamazaki, D.2    Kurisu, S.3    Takenawa, T.4
  • 69
    • 0022733229 scopus 로고
    • Actin cytoskeleton of spread fibroblasts appears to assemble at the cell edges
    • Svitkina, T. M., Neyfakh, A. A., Jr and Bershadsky, A. D. (1986). Actin cytoskeleton of spread fibroblasts appears to assemble at the cell edges. J. Cell Sci. 82, 235-24
    • (1986) J. Cell Sci. , vol.82 , pp. 235-24
    • Svitkina, T.M.1    Neyfakh Jr, A.A.2    Bershadsky, A.D.3
  • 70
    • 70349231029 scopus 로고    scopus 로고
    • Integrated microscopy for real-time imaging of mechanotransduction studies in live cells
    • Trache, A. and Lim, S. M. (2009). Integrated microscopy for real-time imaging of mechanotransduction studies in live cells. J. Biomed. Opt. 14, 03402
    • (2009) J. Biomed. Opt. , vol.14 , pp. 03402
    • Trache, A.1    Lim, S.M.2
  • 72
    • 70350044690 scopus 로고    scopus 로고
    • Golgi polarity does not correlate with speed or persistence of freely migrating fibroblasts
    • Uetrecht, A. C. and Bear, J. E. (2009). Golgi polarity does not correlate with speed or persistence of freely migrating fibroblasts. Eur. J. Cell Biol. 88, 711-71
    • (2009) Eur. J. Cell Biol. , vol.88 , pp. 711-71
    • Uetrecht, A.C.1    Bear, J.E.2
  • 73
    • 13944249955 scopus 로고    scopus 로고
    • Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility
    • Vaynberg, J., Fukuda, T., Chen, K., Vinogradova, O., Velyvis, A., Tu, Y., Ng, L., Wu, C. and Qin, J. (2005). Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility. Mol. Cell 17, 513-52
    • (2005) Mol. Cell , vol.17 , pp. 513-52
    • Vaynberg, J.1    Fukuda, T.2    Chen, K.3    Vinogradova, O.4    Velyvis, A.5    Tu, Y.6    Ng, L.7    Wu, C.8    Qin, J.9
  • 75
    • 33646401549 scopus 로고    scopus 로고
    • Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization
    • Verma, R., Kovari, I., Soofi, A., Nihalani, D., Patrie, K. and Holzman, L. B. (2006). Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J. Clin. Invest. 116, 1346-135
    • (2006) J. Clin. Invest. , vol.116 , pp. 1346-135
    • Verma, R.1    Kovari, I.2    Soofi, A.3    Nihalani, D.4    Patrie, K.5    Holzman, L.B.6
  • 76
    • 33847354235 scopus 로고    scopus 로고
    • Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells
    • Vicente-Manzanares, M., Zareno, J., Whitmore, L., Choi, C. K. and Horwitz, A. F. (2007). Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells. J. Cell Biol. 176, 573-58
    • (2007) J. Cell Biol. , vol.176 , pp. 573-58
    • Vicente-Manzanares, M.1    Zareno, J.2    Whitmore, L.3    Choi, C.K.4    Horwitz, A.F.5
  • 78
    • 79955516270 scopus 로고    scopus 로고
    • Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells
    • Vicente-Manzanares, M., Newell-Litwa, K., Bachir, A. I., Whitmore, L. A. and Horwitz, A. R. (2011). Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells. J. Cell Biol. 193, 381-39
    • (2011) J. Cell Biol. , vol.193 , pp. 381-39
    • Vicente-Manzanares, M.1    Newell-Litwa, K.2    Bachir, A.I.3    Whitmore, L.A.4    Horwitz, A.R.5
  • 80
    • 84863229890 scopus 로고    scopus 로고
    • Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis
    • Wu, C., Asokan, S. B., Berginski, M. E., Haynes, E. M., Sharpless, N. E., Griffith, J. D., Gomez, S. M. and Bear, J. E. (2012). Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis. Cell 148, 973-98
    • (2012) Cell , vol.148 , pp. 973-98
    • Wu, C.1    Asokan, S.B.2    Berginski, M.E.3    Haynes, E.M.4    Sharpless, N.E.5    Griffith, J.D.6    Gomez, S.M.7    Bear, J.E.8
  • 81
    • 57549102276 scopus 로고    scopus 로고
    • Quantitative colocalization analysis of confocal fluorescence microscopy images
    • 4.19.1-4.19.1
    • Zinchuk, V. and Zinchuk, O. (2008). Quantitative colocalization analysis of confocal fluorescence microscopy images. Curr. Protoc Cell Biol. Suppl. 39, 4.19.1-4.19.1
    • (2008) Curr. Protoc Cell Biol. Suppl , vol.39
    • Zinchuk, V.1    Zinchuk, O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.