Caffeine protects against alcohol-induced liver fibrosis by dampening the cAMP/PKA/CREB pathway in rat hepatic stellate cells

International Immunopharmacology

Volumn 25, Issue 2, 2015, Pages 340-352

  Wang, Qi ^a   Dai, Xuefei ^a   Yang, Wanzhi ^b   Wang, He ^a   Zhao, Han ^a   Yang, Feng ^a   Yang, Yan ^a   Li, Jun ^a   Lv, Xiongwen ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b First People's Hospital of Anqing   (China)

Author keywords

Alcoholic liver fibrosis; Caffeine; cAMP; CREB; Hepatic stellate cell; PKA

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; CAFFEINE; COLCHICINE; COLLAGEN TYPE 4; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HYALURONIC ACID; LAMININ; MESSENGER RNA; PROCOLLAGEN; ACTA2 PROTEIN, RAT; ACTIN; COLLAGEN; PEPTIDE FRAGMENT; PROCOLLAGEN TYPE III-N-TERMINAL PEPTIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD SAMPLING; CELL ACTIVATION; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; LIVER; LIVER FIBROSIS; LIVER PERFUSION; LIVER PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; REAL TIME POLYMERASE CHAIN REACTION; STELLATE CELL; WESTERN BLOTTING; ANIMAL; BLOOD; CELL CULTURE; DRUG EFFECTS; LIVER CIRRHOSIS, ALCOHOLIC; LIVER CIRRHOSIS, EXPERIMENTAL; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ACTINS; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CAFFEINE; CELLS, CULTURED; COLLAGEN; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ETHANOL; HEPATIC STELLATE CELLS; HYALURONIC ACID; LAMININ; LIVER; LIVER CIRRHOSIS, ALCOHOLIC; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; PEPTIDE FRAGMENTS; PROCOLLAGEN; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84923651526     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.02.012     Document Type: Article

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