RNA Interference against Discoidin Domain Receptor 2 Ameliorates Alcoholic Liver Disease in Rats

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Luo, Zheng ^a   Liu, Huimin ^b   Sun, Xiaomeng ^a   Guo, Rong ^a   Cui, Ruibing ^a   Ma, Xiangxing ^a   Yan, Ming ^a  

^a SHANDONG UNIVERSITY   (China)

^b QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; COLLAGEN; DISCOIDIN; DISCOIDIN DOMAIN RECEPTOR 2; GELATINASE A; PLASMID VECTOR; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ALCOHOL LIVER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOACCUMULATION; CAPILLARY PROLIFERATION; CELL IMMORTALIZATION; CELL PROLIFERATION; CONTROLLED STUDY; DDR2 GENE; ELECTRON MICROSCOPY; EXPERIMENTAL RAT; EXPRESSION VECTOR; EXTRACELLULAR MATRIX; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIPOSOMAL GENE DELIVERY SYSTEM; LIVER FIBROSIS; LIVER INJURY; LIVER NECROSIS; MALE; MOUSE; NONHUMAN; NONVIRAL GENE THERAPY; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; STELLATE CELL; UPREGULATION; WESTERN BLOTTING;

ACETALDEHYDE; ANIMALS; APOPTOSIS; CELL LINE; CELL PROLIFERATION; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HEPATIC STELLATE CELLS; LIVER; LIVER DISEASES, ALCOHOLIC; MALE; MATRIX METALLOPROTEINASE 2; NECROSIS; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, MITOGEN; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84873573507     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055860     Document Type: Article

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