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Volumn 7, Issue , 2012, Pages 105-117

Molecular serum markers of liver fibrosis

Author keywords

Extracellular matrix; Liver fibrosis; Neo epitope; Serum marker

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; COLLAGEN TYPE 6; CONNECTIVE TISSUE GROWTH FACTOR; ELASTIN; EPIDERMAL GROWTH FACTOR; FIBRONECTIN; GAMMA INTERFERON; GELATINASE A; GELATINASE B; GLYCOPROTEIN; HYALURONIC ACID; INTERLEUKIN 6; LAMININ; MICROFIBRILLAR ASSOCIATED PROTEIN 4; MOLECULAR MARKER; PLATELET DERIVED GROWTH FACTOR; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; PROTEOGLYCAN; SCLEROPROTEIN; SOMATOMEDIN; STROMELYSIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNDULIN; YKL 40 PROTEIN;

EID: 84864619707     PISSN: None     EISSN: 11772719     Source Type: Journal    
DOI: 10.4137/BMI.S10009     Document Type: Review
Times cited : (132)

References (127)
  • 2
    • 0037163917 scopus 로고    scopus 로고
    • FromtheWorldHealthOrganization. Reducingriskstohealth, promotinghealthylife
    • Oct23
    • BrundtlandGH. FromtheWorldHealthOrganization. Reducingriskstohealth, promotinghealthylife. JAMA. Oct23,2002;288(16):1974.
    • (2002) JAMA , vol.288 , Issue.16 , pp. 1974
    • Brundtland, G.H.1
  • 3
    • 0034723290 scopus 로고    scopus 로고
    • Molecularregulationofhepaticfibrosis, anintegratedcellular responsetotissueinjury
    • Jan28
    • FriedmanSL. Molecularregulationofhepaticfibrosis, anintegratedcellular responsetotissueinjury. J Biol Chem. Jan28,2000;275(4):2247-50.
    • (2000) J Biol Chem , vol.275 , Issue.4 , pp. 2247-2250
    • Friedman, S.L.1
  • 4
    • 42949163491 scopus 로고    scopus 로고
    • Mechanismsofhepaticfibrogenesis
    • May
    • FriedmanSL. Mechanismsofhepaticfibrogenesis. Gastroenterology. May2008;134(6):1655-69.
    • (2008) Gastroenterology , vol.134 , Issue.6 , pp. 1655-1669
    • Friedman, S.L.1
  • 5
    • 0037220482 scopus 로고    scopus 로고
    • Liverfibrosis-frombenchtobedside
    • FriedmanSL. Liverfibrosis-frombenchtobedside. J Hepatol.2003;38Suppl1:S38-53.
    • (2003) J Hepatol. , vol.38 , Issue.SUPPL. 1
    • Friedman, S.L.1
  • 6
    • 79551688230 scopus 로고    scopus 로고
    • Abriefreviewonmolecular, geneticandimagingtechniquesforHCVfibrosisevaluation
    • AhmadW, IjazB, GullS, etal. Abriefreviewonmolecular, geneticandimagingtechniquesforHCVfibrosisevaluation. Virol J.2011;8(1):53.
    • (2011) Virol J , vol.8 , Issue.1 , pp. 53
    • Ahmad, W.1    Ijaz, B.2    Gull, S.3
  • 7
    • 33745477366 scopus 로고    scopus 로고
    • Noninvasivefibrosisbiomarkersreducebutnotsubstitutetheneedforliverbiopsy
    • Jun21
    • SebastianiG, AlbertiA. Noninvasivefibrosisbiomarkersreducebutnotsubstitutetheneedforliverbiopsy. World J Gastroenterol. Jun21,2006;12(23):3682-94.
    • (2006) World J Gastroenterol , vol.12 , Issue.23 , pp. 3682-3694
    • Sebastiani, G.1    Alberti, A.2
  • 9
    • 60349096383 scopus 로고    scopus 로고
    • Assessmentoffibrosisinchronicliverdiseases
    • Feb
    • ZhouK, LuLG. Assessmentoffibrosisinchronicliverdiseases. J Dig Dis. Feb2009;10(1):7-14.
    • (2009) J Dig Dis , vol.10 , Issue.1 , pp. 7-14
    • Zhou, K.1    Lu, L.G.2
  • 10
    • 33745760839 scopus 로고    scopus 로고
    • Noninvasivebiochemicalmarkersofliverfibrosis
    • Jun
    • GrigorescuM. Noninvasivebiochemicalmarkersofliverfibrosis. J Gastrointestin Liver Dis. Jun2006;15(2):149-59.
    • (2006) J Gastrointestin Liver Dis , vol.15 , Issue.2 , pp. 149-159
    • Grigorescu, M.1
  • 11
    • 35648963655 scopus 로고    scopus 로고
    • Biomarkersofhepaticfibrosis, fibrogenesisandgeneticpre-dispositionpendingbetweenfictionandreality
    • Sep
    • GressnerOA, WeiskirchenR, GressnerAM. Biomarkersofhepaticfibrosis, fibrogenesisandgeneticpre-dispositionpendingbetweenfictionandreality. J Cell Mol Med. Sep2007;11(5):1031-51.
    • (2007) J Cell Mol Med , vol.11 , Issue.5 , pp. 1031-1051
    • Gressner, O.A.1    Weiskirchen, R.2    Gressner, A.M.3
  • 12
    • 77249095861 scopus 로고    scopus 로고
    • Serummarkersofliverfibrosis:CombiningtheBIPEDclassificationandtheneo-epitopeapproachinthedevelopmentofnewbiomarkers
    • VeidalSS, Bay-JensenAC, TougasG, KarsdalMA, VainerB. Serummarkersofliverfibrosis:combiningtheBIPEDclassificationandtheneo-epitopeapproachinthedevelopmentofnewbiomarkers. Dis Markers. 2010;28(1):15-28.
    • (2010) Dis Markers , vol.28 , Issue.1 , pp. 15-28
    • Veidal, S.S.1    Bay-Jensen, A.C.2    Tougas, G.3    Karsdal, M.A.4    Vainer, B.5
  • 13
    • 0042165989 scopus 로고    scopus 로고
    • Hepatocyteapoptosisandfasexpressionareprominentfeaturesofhumannonalcoholicsteatohepatitis
    • Aug
    • FeldsteinAE, CanbayA, AnguloP, etal. Hepatocyteapoptosisandfasexpressionareprominentfeaturesofhumannonalcoholicsteatohepatitis. Gastroenterology. Aug2003;125(2):437-43.
    • (2003) Gastroenterology , vol.125 , Issue.2 , pp. 437-443
    • Feldstein, A.E.1    Canbay, A.2    Angulo, P.3
  • 14
    • 0033609165 scopus 로고    scopus 로고
    • Endothelialcellandhepatocytedeathsoccurbyapoptosisafterischemia-reperfusioninjuryin the rat liver
    • Apr27
    • KohliV, SelznerM, MaddenJF, BentleyRC, ClavienPA. Endothelialcellandhepatocytedeathsoccurbyapoptosisafterischemia-reperfusioninjuryin the rat liver. Transplantation. Apr27,1999;67(8):1099-105.
    • (1999) Transplantation , vol.67 , Issue.8 , pp. 1099-1105
    • Kohli, V.1    Selzner, M.2    Madden, J.F.3    Bentley, R.C.4    Clavien, P.A.5
  • 15
    • 0033565412 scopus 로고    scopus 로고
    • Apoptosisofsinusoidalendothelialcellsoccursduringliverpreservationinjurybyacaspase-dependentmechanism
    • Jul15
    • NatoriS, SelznerM, ValentinoKL, etal. Apoptosisofsinusoidalendothelialcellsoccursduringliverpreservationinjurybyacaspase-dependentmechanism. Transplantation. Jul15,1999;68(1):89-96.
    • (1999) Transplantation , vol.68 , Issue.1 , pp. 89-96
    • Natori, S.1    Selzner, M.2    Valentino, K.L.3
  • 17
    • 0037342981 scopus 로고    scopus 로고
    • ThecaspaseinhibitorIDN-6556preventscaspaseactivationandapoptosisinsinusoidalendothelialcellsduringliverpreservationinjury
    • Mar
    • NatoriS, HiguchiH, ContrerasP, GoresGJ. ThecaspaseinhibitorIDN-6556preventscaspaseactivationandapoptosisinsinusoidalendothelialcellsduringliverpreservationinjury. Liver Transpl. Mar2003;9(3):278-84.
    • (2003) Liver Transpl , vol.9 , Issue.3 , pp. 278-284
    • Natori, S.1    Higuchi, H.2    Contreras, P.3    Gores, G.J.4
  • 18
    • 0036203442 scopus 로고    scopus 로고
    • Apoptosisandapoptosisrelatedproteinsinchronicviralliverdisease
    • Apr
    • PapakyriakouP, TzardiM, ValatasV, etal. Apoptosisandapoptosisrelatedproteinsinchronicviralliverdisease. Apoptosis. Apr2002;7(2):133-41.
    • (2002) Apoptosis , vol.7 , Issue.2 , pp. 133-141
    • Papakyriakou, P.1    Tzardi, M.2    Valatas, V.3
  • 19
    • 4544335155 scopus 로고    scopus 로고
    • Hepatocyteapoptosis, expressionofdeathreceptors, andactivationofNF-kappaBintheliverofnonalcoholicandalcoholicsteatohepatitispatients
    • Sep
    • RibeiroPS, Cortez-PintoH, SolaS, etal. Hepatocyteapoptosis, expressionofdeathreceptors, andactivationofNF-kappaBintheliverofnonalcoholicandalcoholicsteatohepatitispatients. Am J Gastroenterol. Sep2004;99(9):1708-17.
    • (2004) Am J Gastroenterol , vol.99 , Issue.9 , pp. 1708-1717
    • Ribeiro, P.S.1    Cortez-Pinto, H.2    Sola, S.3
  • 20
    • 15244356690 scopus 로고    scopus 로고
    • Mechanismsofdisease:Mechanismsofhepaticfibrosisandtherapeuticimplications
    • Dec
    • FriedmanSL. Mechanismsofdisease:Mechanismsofhepaticfibrosisandtherapeuticimplications. Nat Clin Pract Gastroenterol Hepatol. Dec2004;1(2):98-105.
    • (2004) Nat Clin Pract Gastroenterol Hepatol , vol.1 , Issue.2 , pp. 98-105
    • Friedman, S.L.1
  • 22
    • 33847350691 scopus 로고    scopus 로고
    • Commonanduniquemechanismsregulatefibrosisinvariousfibroproliferativediseases
    • Mar
    • WynnTA. Commonanduniquemechanismsregulatefibrosisinvariousfibroproliferativediseases. J Clin Invest. Mar2007;117(3):524-9.
    • (2007) J Clin Invest , vol.117 , Issue.3 , pp. 524-529
    • Wynn, T.A.1
  • 23
    • 38549159026 scopus 로고    scopus 로고
    • Cellularandmolecularmechanismsoffibrosis
    • Jan
    • WynnTA. Cellularandmolecularmechanismsoffibrosis. J Pathol. Jan2008;214(2):199-210.
    • (2008) J Pathol , vol.214 , Issue.2 , pp. 199-210
    • Wynn, T.A.1
  • 25
    • 0032794576 scopus 로고    scopus 로고
    • Cytokines and fibrogenesis
    • Friedman SL. Cytokines and fibrogenesis. Semin Liver Dis. 1999;19(2): 129-40.
    • (1999) Semin Liver Dis. , vol.19 , Issue.2 , pp. 129-140
    • Friedman, S.L.1
  • 26
    • 0034810089 scopus 로고    scopus 로고
    • Cytokine receptors and signaling in hepatic stellate cells
    • Aug
    • Pinzani M, Marra F. Cytokine receptors and signaling in hepatic stellate cells. Semin Liver Dis. Aug 2001;21(3):397-416.
    • (2001) Semin Liver Dis , vol.21 , Issue.3 , pp. 397-416
    • Pinzani, M.1    Marra, F.2
  • 27
    • 0033858063 scopus 로고    scopus 로고
    • Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis
    • Aug
    • Arthur MJ. Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis. Am J Physiol Gastrointest Liver Physiol. Aug 2000;279(2):G245-9.
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.279 , Issue.2
    • Arthur, M.J.1
  • 28
    • 0026453596 scopus 로고
    • Secretion of 72kDa type IV collagenase/gelatinase by cultured human lipocytes. Analysis of gene expression, protein synthesis and proteinase activity
    • Nov 1
    • Arthur MJ, Stanley A, Iredale JP, Rafferty JA, Hembry RM, Friedman SL. Secretion of 72kDa type IV collagenase/gelatinase by cultured human lipocytes. Analysis of gene expression, protein synthesis and proteinase activity. Biochem J. Nov 1, 1992;287(Pt 3):701-7.
    • (1992) Biochem J. , vol.287 , Issue.PART 3 , pp. 701-707
    • Arthur, M.J.1    Stanley, A.2    Iredale, J.P.3    Rafferty, J.A.4    Hembry, R.M.5    Friedman, S.L.6
  • 29
    • 73449140168 scopus 로고    scopus 로고
    • Molecular pathogenesis of liver fibrosis
    • Brenner DA. Molecular pathogenesis of liver fibrosis. Trans Am Clin Climatol Assoc. 2009;120:361-8.
    • (2009) Trans Am Clin Climatol Assoc. , vol.120 , pp. 361-368
    • Brenner, D.A.1
  • 30
    • 34250322265 scopus 로고    scopus 로고
    • A matrix metalloproteinase-9 activation cascade by hepatic stellate cells in trans-differentiation in the three-dimensional extracellular matrix
    • Apr 27
    • Han YP, Yan C, Zhou L, Qin L, Tsukamoto H. A matrix metalloproteinase-9 activation cascade by hepatic stellate cells in trans-differentiation in the three-dimensional extracellular matrix. J Biol Chem. Apr 27, 2007; 282(17):12928-39.
    • (2007) J Biol Chem. , vol.282 , Issue.17 , pp. 12928-12939
    • Han, Y.P.1    Yan, C.2    Zhou, L.3    Qin, L.4    Tsukamoto, H.5
  • 32
    • 0029360385 scopus 로고
    • Rat hepatic lipocytes synthesize and secrete transin (stromelysin) in early primary culture
    • Sep
    • Vyas SK, Leyland H, Gentry J, Arthur MJ. Rat hepatic lipocytes synthesize and secrete transin (stromelysin) in early primary culture. Gastroenterology. Sep 1995;109(3):889-98.
    • (1995) Gastroenterology , vol.109 , Issue.3 , pp. 889-898
    • Vyas, S.K.1    Leyland, H.2    Gentry, J.3    Arthur, M.J.4
  • 33
    • 19744377941 scopus 로고    scopus 로고
    • Elevated serum alanine aminotransferase (ALT) levels in patients with serologically verified Mycoplasma pneumoniae pneumonia
    • Jun
    • Daxboeck F, Gattringer R, Mustafa S, Bauer C, Assadian O. Elevated serum alanine aminotransferase (ALT) levels in patients with serologically verified Mycoplasma pneumoniae pneumonia. Clin Microbiol Infect. Jun 2005;11(6):507-10.
    • (2005) Clin Microbiol Infect , vol.11 , Issue.6 , pp. 507-510
    • Daxboeck, F.1    Gattringer, R.2    Mustafa, S.3    Bauer, C.4    Assadian, O.5
  • 34
    • 35348946339 scopus 로고    scopus 로고
    • Clinical significance of activity of ALT enzyme in patients with hepatitis C virus
    • Nov 7
    • Akkaya O, Kiyici M, Yilmaz Y, Ulukaya E, Yerci O. Clinical significance of activity of ALT enzyme in patients with hepatitis C virus. World J Gastroenterol. Nov 7, 2007;13(41):5481-5.
    • (2007) World J Gastroenterol , vol.13 , Issue.41 , pp. 5481-5545
    • Akkaya, O.1    Kiyici, M.2    Yilmaz, Y.3    Ulukaya, E.4    Yerci, O.5
  • 35
    • 0033637463 scopus 로고    scopus 로고
    • Diagnosis and monitoring of hepatic injury. I. Performance characteristics of laboratory tests
    • Dec
    • Dufour DR, Lott JA, Nolte FS, Gretch DR, Koff RS, Seeff LB. Diagnosis and monitoring of hepatic injury. I. Performance characteristics of laboratory tests. Clin Chem. Dec 2000;46(12):2027-49.
    • (2000) Clin Chem , vol.46 , Issue.12 , pp. 2027-2249
    • Dufour, D.R.1    Lott, J.A.2    Nolte, F.S.3    Gretch, D.R.4    Koff, R.S.5    Seeff, L.B.6
  • 36
    • 0025965404 scopus 로고
    • Alanine aminotransferase in clinical practice. A review
    • Feb
    • Sherman KE. Alanine aminotransferase in clinical practice. A review. Arch Intern Med. Feb 1991;151(2):260-5.
    • (1991) Arch Intern Med , vol.151 , Issue.2 , pp. 260-265
    • Sherman, K.E.1
  • 37
    • 33646121757 scopus 로고    scopus 로고
    • Chronic hepatitis C in patients with persistently normal alanine transaminase levels
    • May
    • Shiffman ML, Diago M, Tran A, etal. Chronic hepatitis C in patients with persistently normal alanine transaminase levels. Clin Gastroenterol Hepatol. May 2006;4(5):645-52.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , Issue.5 , pp. 645-652
    • Shiffman, M.L.1    Diago, M.2    Tran, A.3
  • 38
    • 4444247002 scopus 로고    scopus 로고
    • Correlation of serum aminotransferases with HCV RNA levels and histological findings in patients with chronic hepatitis C: The role of serum aspartate transaminase in the evaluation of disease progression
    • Sep
    • Zechini B, Pasquazzi C, Aceti A. Correlation of serum aminotransferases with HCV RNA levels and histological findings in patients with chronic hepatitis C: the role of serum aspartate transaminase in the evaluation of disease progression. Eur J Gastroenterol Hepatol. Sep 2004;16(9):891-6.
    • (2004) Eur J Gastroenterol Hepatol , vol.16 , Issue.9 , pp. 891-896
    • Zechini, B.1    Pasquazzi, C.2    Aceti, A.3
  • 39
    • 0037467777 scopus 로고    scopus 로고
    • Validity and clinical utility of the aspartate aminotransferase-alanine aminotransferase ratio in assessing disease severity and prognosis in patients with hepatitis C virus-related chronic liver disease
    • Jan 27
    • Giannini E, Risso D, Botta F, etal. Validity and clinical utility of the aspartate aminotransferase-alanine aminotransferase ratio in assessing disease severity and prognosis in patients with hepatitis C virus-related chronic liver disease. Arch Intern Med. Jan 27, 2003;163(2):218-24.
    • (2003) Arch Intern Med , vol.163 , Issue.2 , pp. 218-224
    • Giannini, E.1    Risso, D.2    Botta, F.3
  • 40
    • 0032412523 scopus 로고    scopus 로고
    • AST/ALT ratio predicts cirrhosis in patients with chronic hepatitis C virus infection
    • Jan
    • Sheth SG, Flamm SL, Gordon FD, Chopra S. AST/ALT ratio predicts cirrhosis in patients with chronic hepatitis C virus infection. Am J Gastroenterol. Jan 1998;93(1):44-8.
    • (1998) Am J Gastroenterol , vol.93 , Issue.1 , pp. 44-48
    • Sheth, S.G.1    Flamm, S.L.2    Gordon, F.D.3    Chopra, S.4
  • 41
    • 67449100669 scopus 로고    scopus 로고
    • Noninvasive laboratory tests proposed for predicting cirrhosis in patients with chronic hepatitis C are also useful in patients with non-alcoholic steatohepatitis
    • Fujii H, Enomoto M, Fukushima W, et al. Noninvasive laboratory tests proposed for predicting cirrhosis in patients with chronic hepatitis C are also useful in patients with non-alcoholic steatohepatitis. J Gastroenterol. 2009;44(6):608-14.
    • (2009) J Gastroenterol. , vol.44 , Issue.6 , pp. 608-614
    • Fujii, H.1    Enomoto, M.2    Fukushima, W.3
  • 42
    • 20044389095 scopus 로고    scopus 로고
    • Comparison and validation of simple noninvasive tests for prediction of fibrosis in chronic hepatitis C
    • Jun
    • Lackner C, Struber G, Liegl B, et al. Comparison and validation of simple noninvasive tests for prediction of fibrosis in chronic hepatitis C. Hepatology. Jun 2005;41(6):1376-82.
    • (2005) Hepatology , vol.41 , Issue.6 , pp. 1376-1382
    • Lackner, C.1    Struber, G.2    Liegl, B.3
  • 43
    • 0031696864 scopus 로고    scopus 로고
    • AST/ALT ratio. or= 1 is not diagnostic of cirrhosis in patients with chronic hepatitis C
    • Sep
    • Reedy DW, Loo AT, Levine RA. AST/ALT ratio. or= 1 is not diagnostic of cirrhosis in patients with chronic hepatitis C. Dig Dis Sci. Sep 1998; 43(9):2156-9.
    • (1998) Dig Dis Sci. , vol.43 , Issue.9 , pp. 2156-2159
    • Reedy, D.W.1    Loo, A.T.2    Levine, R.A.3
  • 44
    • 0034100952 scopus 로고    scopus 로고
    • Is liver fibrosis reversible?
    • Apr
    • Benyon RC, Iredale JP. Is liver fibrosis reversible? Gut. Apr 2000; 46(4):443-6.
    • (2000) Gut. , vol.46 , Issue.4 , pp. 443-446
    • Benyon, R.C.1    Iredale, J.P.2
  • 45
    • 0242710145 scopus 로고    scopus 로고
    • Collagens-structure, function, and biosynthesis
    • Nov 28
    • Gelse K, Poschl E, Aigner T. Collagens-structure, function, and biosynthesis. Adv Drug Deliv Rev. Nov 28, 2003;55(12):1531-46.
    • (2003) Adv Drug Deliv Rev , vol.55 , Issue.12 , pp. 1531-1546
    • Gelse, K.1    Poschl, E.2    Aigner, T.3
  • 46
    • 0043172449 scopus 로고    scopus 로고
    • Serum levels of YKL-40 and PIIINP as prognostic markers in patients with alcoholic liver disease
    • Aug
    • Nojgaard C, Johansen JS, Christensen E, Skovgaard LT, Price PA, Becker U. Serum levels of YKL-40 and PIIINP as prognostic markers in patients with alcoholic liver disease. J Hepatol. Aug 2003;39(2):179-86.
    • (2003) J Hepatol , vol.39 , Issue.2 , pp. 179-186
    • Nojgaard, C.1    Johansen, J.S.2    Christensen, E.3    Skovgaard, L.T.4    Price, P.A.5    Becker, U.6
  • 47
    • 9644279531 scopus 로고    scopus 로고
    • Serum markers detect the presence of liver fibrosis: A cohort study
    • Dec
    • Rosenberg WM, Voelker M, Thiel R, etal. Serum markers detect the presence of liver fibrosis: a cohort study. Gastroenterology. Dec 2004; 127(6):1704-13.
    • (2004) Gastroenterology. , vol.127 , Issue.6 , pp. 1704-1713
    • Rosenberg, W.M.1    Voelker, M.2    Thiel, R.3
  • 48
    • 0027521937 scopus 로고
    • Comparison of serum procollagen III peptide concentrations and PGA index for assessment of hepatic fibrosis
    • Oct 9
    • Teare JP, Sherman D, Greenfield SM, etal. Comparison of serum procollagen III peptide concentrations and PGA index for assessment of hepatic fibrosis. Lancet. Oct 9, 1993;342(8876):895-8.
    • (1993) Lancet , vol.342 , Issue.8876 , pp. 895-898
    • Teare, J.P.1    Sherman, D.2    Greenfield, S.M.3
  • 49
    • 0028276682 scopus 로고
    • Role of the measurement of serum procollagen type III N-terminal peptide in the evaluation of liver diseases
    • Jun
    • Collazos J, Diaz F. Role of the measurement of serum procollagen type III N-terminal peptide in the evaluation of liver diseases. Clin Chim Acta. Jun 1994;227(1-2):37-43.
    • (1994) Clin Chim Acta , vol.227 , Issue.1-2 , pp. 37-43
    • Collazos, J.1    Diaz, F.2
  • 50
    • 0030865384 scopus 로고    scopus 로고
    • Serum laminin and type III procollagen in chronic hepatitis C. Diagnostic value in the assessment of disease activity and fibrosis
    • Sep 8
    • Gabrielli GB, Capra F, Casaril M, et al. Serum laminin and type III procollagen in chronic hepatitis C. Diagnostic value in the assessment of disease activity and fibrosis. Clin Chim Acta. Sep 8, 1997;265(1):21-31.
    • (1997) Clin Chim Acta , vol.265 , Issue.1 , pp. 21-31
    • Gabrielli, G.B.1    Capra, F.2    Casaril, M.3
  • 51
    • 0035131158 scopus 로고    scopus 로고
    • Serum pro-collagen III peptide levels are related to lobular necrosis in untreated patients with chronic hepatitis C
    • Feb
    • Giannini E, Caglieris S, Ceppa P, Risso D, Lantieri PB, Testa R. Serum pro-collagen III peptide levels are related to lobular necrosis in untreated patients with chronic hepatitis C. Eur J Gastroenterol Hepatol. Feb 2001; 13(2):137-41.
    • (2001) Eur J Gastroenterol Hepatol. , vol.13 , Issue.2 , pp. 137-141
    • Giannini, E.1    Caglieris, S.2    Ceppa, P.3    Risso, D.4    Lantieri, P.B.5    Testa, R.6
  • 52
    • 0029879030 scopus 로고    scopus 로고
    • Diagnostic accuracy of hyaluronan and type III procollagen amino-terminal peptide serum assays as markers of liver fibrosis in chronic viral hepatitis C evaluated by ROC curve analysis
    • Apr
    • Guechot J, Laudat A, Loria A, Serfaty L, Poupon R, Giboudeau J. Diagnostic accuracy of hyaluronan and type III procollagen amino-terminal peptide serum assays as markers of liver fibrosis in chronic viral hepatitis C evaluated by ROC curve analysis. Clin Chem. Apr 1996; 42(4):558-63.
    • (1996) Clin Chem. , vol.42 , Issue.4 , pp. 558-563
    • Guechot, J.1    Laudat, A.2    Loria, A.3    Serfaty, L.4    Poupon, R.5    Giboudeau, J.6
  • 53
    • 0030594039 scopus 로고    scopus 로고
    • Procollagen III and laminin in chronic viral hepatopathies
    • Jan 20
    • Montalto G, Soresi M, Aragona F, et al. Procollagen III and laminin in chronic viral hepatopathies. Presse Med. Jan 20, 1996;25(2):59-62.
    • (1996) Presse Med , vol.25 , Issue.2 , pp. 59-62
    • Montalto, G.1    Soresi, M.2    Aragona, F.3
  • 54
    • 34248207324 scopus 로고    scopus 로고
    • Biomarkers of liver fibrosis: Clinical translation of molecular pathogenesis or based on liver-dependent malfunction tests
    • Jun
    • Gressner OA, Weiskirchen R, Gressner AM. Biomarkers of liver fibrosis: clinical translation of molecular pathogenesis or based on liver-dependent malfunction tests. Clin Chim Acta. Jun 2007;381(2):107-13.
    • (2007) Clin Chim Acta , vol.381 , Issue.2 , pp. 107-113
    • Gressner, O.A.1    Weiskirchen, R.2    Gressner, A.M.3
  • 55
    • 0031062773 scopus 로고    scopus 로고
    • Significance of elevated procollagen-III-peptide and transforming growth factor-beta levels of bronchoalveolar lavage fluids from idiopathic pulmonary fibrosis patients
    • Feb
    • Hiwatari N, Shimura S, Yamauchi K, Nara M, Hida W, Shirato K. Significance of elevated procollagen-III-peptide and transforming growth factor-beta levels of bronchoalveolar lavage fluids from idiopathic pulmonary fibrosis patients. Tohoku J Exp Med. Feb 1997;181(2):285-95.
    • (1997) Tohoku J Exp Med , vol.181 , Issue.2 , pp. 285-295
    • Hiwatari, N.1    Shimura, S.2    Yamauchi, K.3    Nara, M.4    Hida, W.5    Shirato, K.6
  • 56
    • 0032805729 scopus 로고    scopus 로고
    • Serum levels of extracellular matrix in acute pancreatitis
    • Nov
    • Lohr M, Hummel F, Martus P, etal. Serum levels of extracellular matrix in acute pancreatitis. Hepatogastroenterology. Nov 1999;46(30): 3263-70.
    • (1999) Hepatogastroenterology , vol.46 , Issue.30 , pp. 3263-3370
    • Lohr, M.1    Hummel, F.2    Martus, P.3
  • 57
    • 0027070961 scopus 로고
    • Serum N terminal procollagen III fragment: A predictive marker of joint destruction in rheumatoid arthritis?
    • Dec
    • Tebib JG, Viguier P, Noel E, Colson F, Barbier Y, Bouvier M. Serum N terminal procollagen III fragment: a predictive marker of joint destruction in rheumatoid arthritis? Clin Rheumatol. Dec 1992;11(4):502-7.
    • (1992) Clin Rheumatol , vol.11 , Issue.4 , pp. 502-557
    • Tebib, J.G.1    Viguier, P.2    Noel, E.3    Colson, F.4    Barbier, Y.5    Bouvier, M.6
  • 58
    • 0026267725 scopus 로고
    • Hepatic fibrosis and its serum markers: A review
    • Gabrielli GB, Corrocher R. Hepatic fibrosis and its serum markers: a review. Dig Dis. 1991;9(5):303-16.
    • (1991) Dig Dis. , vol.9 , Issue.5 , pp. 303-316
    • Gabrielli, G.B.1    Corrocher, R.2
  • 60
    • 0029929470 scopus 로고    scopus 로고
    • Serum type IV collagen in various liver diseases in comparison with serum 7S collagen, laminin, and type III procollagen peptide
    • Apr
    • Hirayama C, Suzuki H, Takada A, Fujisawa K, Tanikawa K, Igarashi S. Serum type IV collagen in various liver diseases in comparison with serum 7S collagen, laminin, and type III procollagen peptide. J Gastroenterol. Apr 1996;31(2):242-8.
    • (1996) J Gastroenterol , vol.31 , Issue.2 , pp. 242-248
    • Hirayama, C.1    Suzuki, H.2    Takada, A.3    Fujisawa, K.4    Tanikawa, K.5    Igarashi, S.6
  • 61
    • 84861306189 scopus 로고    scopus 로고
    • Enzyme-linked immunosorbent serum assay specific for the 7S domain of Collagen Type IV (P4NP 7S): A marker related to the extracellular matrix remodeling during liver fibrogenesis
    • Jan 5
    • Leeming DJ, Nielsen MJ, Dai Y, etal. Enzyme-linked immunosorbent serum assay specific for the 7S domain of Collagen Type IV (P4NP 7S): A marker related to the extracellular matrix remodeling during liver fibrogenesis. Hepatol Res. Jan 5, 2012.
    • (2012) Hepatol Res.
    • Leeming, D.J.1    Nielsen, M.J.2    Dai, Y.3
  • 62
    • 79960397931 scopus 로고    scopus 로고
    • Procollagen type I N-terminal propeptide (PINP) is a marker for fibrogenesis in bile duct ligation-induced fibrosis in rats
    • Veidal SS, Vassiliadis E, Bay-Jensen AC, Tougas G, Vainer B, Karsdal MA. Procollagen type I N-terminal propeptide (PINP) is a marker for fibrogenesis in bile duct ligation-induced fibrosis in rats. Fibrogenesis Tissue Repair. 2010;3(1):5.
    • (2010) Fibrogenesis Tissue Repair. , vol.3 , Issue.1 , pp. 5
    • Veidal, S.S.1    Vassiliadis, E.2    Bay-Jensen, A.C.3    Tougas, G.4    Vainer, B.5    Karsdal, M.A.6
  • 63
    • 0033395339 scopus 로고    scopus 로고
    • Hepatic and renal extraction of circulating type I procollagen aminopropeptide in patients with normal liver function and in patients with alcoholic cirrhosis
    • Dec
    • Schytte S, Hansen M, Moller S, et al. Hepatic and renal extraction of circulating type I procollagen aminopropeptide in patients with normal liver function and in patients with alcoholic cirrhosis. Scand J Clin Lab Invest. Dec 1999;59(8):627-33.
    • (1999) Scand J Clin Lab Invest , vol.59 , Issue.8 , pp. 627-633
    • Schytte, S.1    Hansen, M.2    Moller, S.3
  • 64
    • 79960788301 scopus 로고    scopus 로고
    • Immunological detection of the type V collagen propeptide fragment, PVCP-1230, in connective tissue remodeling associated with liver fibrosis
    • Aug
    • Vassiliadis E, Veidal SS, Simonsen H, etal. Immunological detection of the type V collagen propeptide fragment, PVCP-1230, in connective tissue remodeling associated with liver fibrosis. Biomarkers. Aug 2011; 16(5):426-33.
    • (2011) Biomarkers. , vol.16 , Issue.5 , pp. 426-433
    • Vassiliadis, E.1    Veidal, S.S.2    Simonsen, H.3
  • 65
    • 0024545265 scopus 로고
    • Endocytosis of hyaluronic acid by rat liver endothelial cells. Evidence for receptor recycling
    • Feb 1
    • McGary CT, Raja RH, Weigel PH. Endocytosis of hyaluronic acid by rat liver endothelial cells. Evidence for receptor recycling. Biochem J. Feb 1, 1989;257(3):875-84.
    • (1989) Biochem J , vol.257 , Issue.3 , pp. 875-884
    • McGary, C.T.1    Raja, R.H.2    Weigel, P.H.3
  • 66
    • 0033804405 scopus 로고    scopus 로고
    • Measurement of serum hyaluronic acid in patients with chronic hepatitis C and its relationship to liver histology. Consensus Interferon Study Group
    • Aug
    • McHutchison JG, Blatt LM, De Medina M, et al. Measurement of serum hyaluronic acid in patients with chronic hepatitis C and its relationship to liver histology. Consensus Interferon Study Group. J Gastroenterol Hepatol. Aug 2000;15(8):945-51.
    • (2000) J Gastroenterol Hepatol , vol.15 , Issue.8 , pp. 945-951
    • McHutchison, J.G.1    Blatt, L.M.2    de Medina, M.3
  • 67
    • 0041408163 scopus 로고    scopus 로고
    • Serum hyaluronate correlates with histological progression in alcoholic liver disease
    • Sep
    • Stickel F, Poeschl G, Schuppan D, et al. Serum hyaluronate correlates with histological progression in alcoholic liver disease. Eur J Gastroenterol Hepatol. Sep 2003;15(9):945-50.
    • (2003) Eur J Gastroenterol Hepatol , vol.15 , Issue.9 , pp. 945-950
    • Stickel, F.1    Poeschl, G.2    Schuppan, D.3
  • 68
    • 0031876788 scopus 로고    scopus 로고
    • Serum hyaluronic acid is a useful marker of liver fibrosis in chronic hepatitis C virus infection
    • May
    • Wong VS, Hughes V, Trull A, Wight DG, Petrik J, Alexander GJ. Serum hyaluronic acid is a useful marker of liver fibrosis in chronic hepatitis C virus infection. J Viral Hepat. May 1998;5(3):187-92.
    • (1998) J Viral Hepat , vol.5 , Issue.3 , pp. 187-192
    • Wong, V.S.1    Hughes, V.2    Trull, A.3    Wight, D.G.4    Petrik, J.5    Alexander, G.J.6
  • 69
    • 67650188604 scopus 로고    scopus 로고
    • Non-invasive biomarkers for monitoring the fibrogenic process in liver: A short survey
    • May 28
    • Gressner AM, Gao CF, Gressner OA. Non-invasive biomarkers for monitoring the fibrogenic process in liver: a short survey. World J Gastroenterol. May 28, 2009;15(20):2433-40.
    • (2009) World J Gastroenterol , vol.15 , Issue.20 , pp. 2433-2440
    • Gressner, A.M.1    Gao, C.F.2    Gressner, O.A.3
  • 70
    • 0030004293 scopus 로고    scopus 로고
    • Measurement of serum hyaluronic acid in patients with rheumatoid arthritis: Correlation with disease activity
    • Jun
    • Emlen W, Niebur J, Flanders G, Rutledge J. Measurement of serum hyaluronic acid in patients with rheumatoid arthritis: correlation with disease activity. J Rheumatol. Jun 1996;23(6):974-8.
    • (1996) J Rheumatol , vol.23 , Issue.6 , pp. 974-998
    • Emlen, W.1    Niebur, J.2    Flanders, G.3    Rutledge, J.4
  • 71
    • 27544456388 scopus 로고    scopus 로고
    • Mechanisms by which food intake elevates circulating levels of hyaluronan in humans
    • Nov
    • Fraser JR, Gibson PR. Mechanisms by which food intake elevates circulating levels of hyaluronan in humans. J Intern Med. Nov 2005; 258(5):460-6.
    • (2005) J Intern Med. , vol.258 , Issue.5 , pp. 460-466
    • Fraser, J.R.1    Gibson, P.R.2
  • 72
    • 0033831478 scopus 로고    scopus 로고
    • Chondrex (YKL-40), a potential new serum fibrosis marker in patients with alcoholic liver disease
    • Sep
    • Tran A, Benzaken S, Saint-Paul MC, etal. Chondrex (YKL-40), a potential new serum fibrosis marker in patients with alcoholic liver disease. Eur J Gastroenterol Hepatol. Sep 2000;12(9):989-93.
    • (2000) Eur J Gastroenterol Hepatol , vol.12 , Issue.9 , pp. 989-993
    • Tran, A.1    Benzaken, S.2    Saint-Paul, M.C.3
  • 73
    • 58149316013 scopus 로고    scopus 로고
    • A functional variation in CHI3L1 is associated with severity of liver fibrosis and YKL-40serum levels in chronic hepatitis C infection
    • Feb
    • Berres ML, Papen S, Pauels K, et al. A functional variation in CHI3L1 is associated with severity of liver fibrosis and YKL-40serum levels in chronic hepatitis C infection. J Hepatol. Feb 2009;50(2):370-6.
    • (2009) J Hepatol , vol.50 , Issue.2 , pp. 370-376
    • Berres, M.L.1    Papen, S.2    Pauels, K.3
  • 74
    • 13244255642 scopus 로고    scopus 로고
    • Noninvasive estimation of liver fibrosis and response to interferon therapy by a serum fibrogenesis marker, YKL-40, in patients with HCV-associated liver disease
    • Jan 28
    • Saitou Y, Shiraki K, Yamanaka Y, etal. Noninvasive estimation of liver fibrosis and response to interferon therapy by a serum fibrogenesis marker, YKL-40, in patients with HCV-associated liver disease. World J Gastroenterol. Jan 28, 2005;11(4):476-81.
    • (2005) World J Gastroenterol , vol.11 , Issue.4 , pp. 476-481
    • Saitou, Y.1    Shiraki, K.2    Yamanaka, Y.3
  • 75
    • 33646842919 scopus 로고    scopus 로고
    • Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer
    • May
    • Johansen JS. Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer. Dan Med Bull. May 2006;53(2):172-209.
    • (2006) Dan Med Bull , vol.53 , Issue.2 , pp. 172-209
    • Johansen, J.S.1
  • 76
    • 65449125801 scopus 로고    scopus 로고
    • Detection of novel biomarkers of liver cirrhosis by proteomic analysis
    • Apr
    • Molleken C, Sitek B, Henkel C, et al. Detection of novel biomarkers of liver cirrhosis by proteomic analysis. Hepatology. Apr 2009;49(4):1257-66.
    • (2009) Hepatology , vol.49 , Issue.4 , pp. 1257-1266
    • Molleken, C.1    Sitek, B.2    Henkel, C.3
  • 77
    • 1442301501 scopus 로고    scopus 로고
    • Circulating matrix metalloproteinases 1, 2, 9 and their inhibitors TIMP-1 and TIMP-2 as serum markers of liver fibrosis in patients with chronic hepatitis C: Comparison with PIIINP and hyaluronic acid
    • Feb
    • Leroy V, Monier F, Bottari S, etal. Circulating matrix metalloproteinases 1, 2, 9 and their inhibitors TIMP-1 and TIMP-2 as serum markers of liver fibrosis in patients with chronic hepatitis C: comparison with PIIINP and hyaluronic acid. Am J Gastroenterol. Feb 2004;99(2):271-9.
    • (2004) Am J Gastroenterol , vol.99 , Issue.2 , pp. 271-279
    • Leroy, V.1    Monier, F.2    Bottari, S.3
  • 78
    • 0037192866 scopus 로고    scopus 로고
    • Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: Implications for reversibility of liver fibrosis
    • Mar 29
    • Murphy FR, Issa R, Zhou X, et al. Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis. J Biol Chem. Mar 29, 2002;277(13):11069-76.
    • (2002) J Biol Chem , vol.277 , Issue.13 , pp. 11069-11076
    • Murphy, F.R.1    Issa, R.2    Zhou, X.3
  • 79
    • 0032808034 scopus 로고    scopus 로고
    • Collagen breakdown in soft connective tissue explants is associated with the level of active gelatinase A (MMP-2) but not with collagenase
    • Aug
    • Kerkvliet EH, Docherty AJ, Beertsen W, Everts V. Collagen breakdown in soft connective tissue explants is associated with the level of active gelatinase A (MMP-2) but not with collagenase. Matrix Biol. Aug 1999; 18(4):373-80.
    • (1999) Matrix Biol. , vol.18 , Issue.4 , pp. 373-380
    • Kerkvliet, E.H.1    Docherty, A.J.2    Beertsen, W.3    Everts, V.4
  • 80
    • 0033020765 scopus 로고    scopus 로고
    • Plasma levels of matrix metalloproteinase-2 (MMP-2) and tissue inhibitors of metalloproteinases-1 and-2 (TIMP-1 and TIMP-2) as noninvasive markers of liver disease in chronic hepatitis C: Comparison using ROC analysis
    • Mar
    • Walsh KM, Timms P, Campbell S, MacSween RN, Morris AJ. Plasma levels of matrix metalloproteinase-2 (MMP-2) and tissue inhibitors of metalloproteinases-1 and-2 (TIMP-1 and TIMP-2) as noninvasive markers of liver disease in chronic hepatitis C: comparison using ROC analysis. Dig Dis Sci. Mar 1999;44(3):624-30.
    • (1999) Dig Dis Sci , vol.44 , Issue.3 , pp. 624-630
    • Walsh, K.M.1    Timms, P.2    Campbell, S.3    McSween, R.N.4    Morris, A.J.5
  • 81
    • 0036135242 scopus 로고    scopus 로고
    • Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C
    • Feb
    • Boeker KH, Haberkorn CI, Michels D, Flemming P, Manns MP, Lichtinghagen R. Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C. Clin Chim Acta. Feb 2002;316(1-2):71-81.
    • (2002) Clin Chim Acta , vol.316 , Issue.1-2 , pp. 71-81
    • Boeker, K.H.1    Haberkorn, C.I.2    Michels, D.3    Flemming, P.4    Manns, M.P.5    Lichtinghagen, R.6
  • 82
    • 77953706518 scopus 로고    scopus 로고
    • Novel combinations of Post-Translational Modification (PTM) neo-epitopes provide tissue-specific biochemical markers-are they the cause or the consequence of the disease?
    • Jul
    • Karsdal MA, Henriksen K, Leeming DJ, Woodworth T, Vassiliadis E, Bay-Jensen AC. Novel combinations of Post-Translational Modification (PTM) neo-epitopes provide tissue-specific biochemical markers-are they the cause or the consequence of the disease? Clin Biochem. Jul 2010; 43(10-11):793-804.
    • (2010) Clin Biochem. , vol.43 , Issue.10-11 , pp. 793-804
    • Karsdal, M.A.1    Henriksen, K.2    Leeming, D.J.3    Woodworth, T.4    Vassiliadis, E.5    Bay-Jensen, A.C.6
  • 83
    • 0037898391 scopus 로고    scopus 로고
    • Neoepitopes as biomarkers of cartilage catabolism
    • Jun
    • Fosang AJ, Stanton H, Little CB, Atley LM. Neoepitopes as biomarkers of cartilage catabolism. Inflamm Res. Jun 2003;52(7):277-82.
    • (2003) Inflamm Res , vol.52 , Issue.7 , pp. 277-282
    • Fosang, A.J.1    Stanton, H.2    Little, C.B.3    Atley, L.M.4
  • 84
    • 66149103673 scopus 로고    scopus 로고
    • Biochemical markers and the FDA Critical Path: How biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development
    • May
    • Karsdal MA, Henriksen K, Leeming DJ, et al. Biochemical markers and the FDA Critical Path: how biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development. Biomarkers. May 2009;14(3):181-202.
    • (2009) Biomarkers , vol.14 , Issue.3 , pp. 181-202
    • Karsdal, M.A.1    Henriksen, K.2    Leeming, D.J.3
  • 85
    • 77953718011 scopus 로고    scopus 로고
    • A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen
    • Jul
    • Barascuk N, Veidal SS, Larsen L, et al. A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen. Clin Biochem. Jul 2010;43(10-11):899-904.
    • (2010) Clin Biochem , vol.43 , Issue.10-11 , pp. 899-904
    • Barascuk, N.1    Veidal, S.S.2    Larsen, L.3
  • 86
    • 80052806957 scopus 로고    scopus 로고
    • Circulating CO3-610, a degradation product of collagen III, closely reflects liver collagen and portal pressure in rats with fibrosis
    • Segovia-Silvestre T, Reichenbach V, Fernandez-Varo G, etal. Circulating CO3-610, a degradation product of collagen III, closely reflects liver collagen and portal pressure in rats with fibrosis. Fibrogenesis Tissue Repair. 2011;4:19.
    • (2011) Fibrogenesis Tissue Repair. , vol.4 , pp. 19
    • Segovia-Silvestre, T.1    Reichenbach, V.2    Fernandez-Varo, G.3
  • 87
    • 79958242395 scopus 로고    scopus 로고
    • Measurement of CO3-610, a Potential Liver Biomarker Derived from Matrix Metalloproteinase-9 Degradation of Collagen Type III, in a Rat Model of Reversible Carbon-Tetrachloride-Induced Fibrosis
    • Vassiliadis E, Larsen DV, Clausen RE, etal. Measurement of CO3-610, a Potential Liver Biomarker Derived from Matrix Metalloproteinase-9 Degradation of Collagen Type III, in a Rat Model of Reversible Carbon-Tetrachloride-Induced Fibrosis. Biomark Insights. 2011;6:49-58.
    • (2011) Biomark Insights. , vol.6 , pp. 49-58
    • Vassiliadis, E.1    Larsen, D.V.2    Clausen, R.E.3
  • 88
    • 80054983554 scopus 로고    scopus 로고
    • Assessment of proteolytic degradation of the basement membrane: A fragment of type IV collagen as a biochemical marker for liver fibrosis
    • Veidal SS, Karsdal MA, Nawrocki A, et al. Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis. Fibrogenesis Tissue Repair. 2011;4:22.
    • (2011) Fibrogenesis Tissue Repair. , vol.4 , pp. 22
    • Veidal, S.S.1    Karsdal, M.A.2    Nawrocki, A.3
  • 89
    • 80052830980 scopus 로고    scopus 로고
    • MMP mediated degradation of type VI collagen is highly associated with liver fibrosis-identification and validation of a novel biochemical marker assay
    • Veidal SS, Karsdal MA, Vassiliadis E, etal. MMP mediated degradation of type VI collagen is highly associated with liver fibrosis-identification and validation of a novel biochemical marker assay. PLoS One. 2011; 6(9):e24753.
    • (2011) PLoS One. , vol.6 , Issue.9
    • Veidal, S.S.1    Karsdal, M.A.2    Vassiliadis, E.3
  • 90
    • 80054906939 scopus 로고    scopus 로고
    • A novel marker for assessment of liver matrix remodeling: An enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M)
    • Nov
    • Leeming D, He Y, Veidal S, etal. A novel marker for assessment of liver matrix remodeling: an enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M). Biomarkers. Nov 2011;16(7):616-28.
    • (2011) Biomarkers , vol.16 , Issue.7 , pp. 616-628
    • Leeming, D.1    He, Y.2    Veidal, S.3
  • 91
    • 54549098072 scopus 로고    scopus 로고
    • Cytokines and renin-angiotensin system signaling in hepatic fibrosis
    • Nov
    • Moreno M, Bataller R. Cytokines and renin-angiotensin system signaling in hepatic fibrosis. Clin Liver Dis. Nov 2008;12(4):825-52.
    • (2008) Clin Liver Dis , vol.12 , Issue.4 , pp. 825-852
    • Moreno, M.1    Bataller, R.2
  • 92
    • 0035552143 scopus 로고    scopus 로고
    • Prediction of progressive liver fibrosis in hepatitis C infection by serum and tissue levels of transforming growth factor-beta
    • Nov
    • Kanzler S, Baumann M, Schirmacher P, etal. Prediction of progressive liver fibrosis in hepatitis C infection by serum and tissue levels of transforming growth factor-beta. J Viral Hepat. Nov 2001;8(6):430-7.
    • (2001) J Viral Hepat , vol.8 , Issue.6 , pp. 430-447
    • Kanzler, S.1    Baumann, M.2    Schirmacher, P.3
  • 93
    • 0036375125 scopus 로고    scopus 로고
    • Plasma tissue inhibitor of metalloproteinases-1 and transforming growth factor beta 1-possible non-invasive biomarkers of hepatic fibrosis in patients with chronic B and C hepatitis
    • Sep
    • Flisiak R, Maxwell P, Prokopowicz D, Timms PM, Panasiuk A. Plasma tissue inhibitor of metalloproteinases-1 and transforming growth factor beta 1-possible non-invasive biomarkers of hepatic fibrosis in patients with chronic B and C hepatitis. Hepatogastroenterology. Sep 2002; 49(47):1369-72.
    • (2002) Hepatogastroenterology. , vol.49 , Issue.47 , pp. 1369-1372
    • Flisiak, R.1    Maxwell, P.2    Prokopowicz, D.3    Timms, P.M.4    Panasiuk, A.5
  • 94
    • 0031948431 scopus 로고    scopus 로고
    • Latent transforming growth factor beta in liver parenchymal cells, its injury-dependent release, and paracrine effects on rat hepatic stellate cells
    • Apr
    • Roth S, Michel K, Gressner AM. (Latent) transforming growth factor beta in liver parenchymal cells, its injury-dependent release, and paracrine effects on rat hepatic stellate cells. Hepatology. Apr 1998;27(4):1003-12.
    • (1998) Hepatology , vol.27 , Issue.4 , pp. 1003-1012
    • Roth, S.1    Michel, K.2    Gressner, A.M.3
  • 95
    • 32044431702 scopus 로고    scopus 로고
    • Dysregulated cytokine metabolism, altered hepatic methionine metabolism and proteasome dysfunction in alcoholic liver disease
    • Nov
    • McClain C, Barve S, Joshi-Barve S, et al. Dysregulated cytokine metabolism, altered hepatic methionine metabolism and proteasome dysfunction in alcoholic liver disease. Alcohol Clin Exp Res. Nov 2005; 29(Suppl 11):180S-8S.
    • (2005) Alcohol Clin Exp Res. , vol.29 , Issue.SUPPL. 11
    • McClain, C.1    Barve, S.2    Joshi-Barve, S.3
  • 96
    • 22144446395 scopus 로고    scopus 로고
    • Relationship between serum cytokine levels and histopathological changes of liver in patients with hepatitis B
    • Jun 7
    • Akpolat N, Yahsi S, Godekmerdan A, Demirbag K, Yalniz M. Relationship between serum cytokine levels and histopathological changes of liver in patients with hepatitis B. World J Gastroenterol. Jun 7, 2005; 11(21):3260-3.
    • (2005) World J Gastroenterol. , vol.11 , Issue.21 , pp. 3260-3263
    • Akpolat, N.1    Yahsi, S.2    Godekmerdan, A.3    Demirbag, K.4    Yalniz, M.5
  • 98
    • 2942682928 scopus 로고    scopus 로고
    • Regulation of PDGF and its receptors in fibrotic diseases
    • Aug
    • Bonner JC. Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev. Aug 2004;15(4):255-73.
    • (2004) Cytokine Growth Factor Rev , vol.15 , Issue.4 , pp. 255-273
    • Bonner, J.C.1
  • 99
    • 0344467413 scopus 로고    scopus 로고
    • Diagnostic value of platelet derived growth factor-BB, transforming growth factor-beta1, matrix metalloproteinase-1, and tissue inhibitor of matrix metalloproteinase-1in serum and peripheral blood mononuclear cells for hepatic fibrosis
    • Nov
    • Zhang BB, Cai WM, Weng HL, et al. Diagnostic value of platelet derived growth factor-BB, transforming growth factor-beta1, matrix metalloproteinase-1, and tissue inhibitor of matrix metalloproteinase-1in serum and peripheral blood mononuclear cells for hepatic fibrosis. World J Gastroenterol. Nov 2003;9(11):2490-6.
    • (2003) World J Gastroenterol , vol.9 , Issue.11 , pp. 2490-2496
    • Zhang, B.B.1    Cai, W.M.2    Weng, H.L.3
  • 100
    • 34848865661 scopus 로고    scopus 로고
    • Differential effects of TGF-beta on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes
    • Nov
    • Gressner OA, Lahme B, Demirci I, Gressner AM, Weiskirchen R. Differential effects of TGF-beta on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes. J Hepatol. Nov 2007;47(5):699-710.
    • (2007) J Hepatol , vol.47 , Issue.5 , pp. 699-710
    • Gressner, O.A.1    Lahme, B.2    Demirci, I.3    Gressner, A.M.4    Weiskirchen, R.5
  • 101
    • 48949084865 scopus 로고    scopus 로고
    • Connective tissue growth factor: A fibrogenic master switch in fibrotic liver diseases
    • Sep
    • Gressner OA, Gressner AM. Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases. Liver Int. Sep 2008;28(8): 1065-79.
    • (2008) Liver Int , vol.28 , Issue.8 , pp. 1065-1179
    • Gressner, O.A.1    Gressner, A.M.2
  • 102
    • 33748308746 scopus 로고    scopus 로고
    • Connective tissue growth factor in serum as a new candidate test for assessment of hepatic fibrosis
    • Sep
    • Gressner AM, Yagmur E, Lahme B, Gressner O, Stanzel S. Connective tissue growth factor in serum as a new candidate test for assessment of hepatic fibrosis. Clin Chem. Sep 2006;52(9):1815-7.
    • (2006) Clin Chem , vol.52 , Issue.9 , pp. 1815-1817
    • Gressner, A.M.1    Yagmur, E.2    Lahme, B.3    Gressner, O.4    Stanzel, S.5
  • 103
    • 68949198361 scopus 로고    scopus 로고
    • Validation of connective tissue growth factor (CTGF/CCN2) and its gene polymorphisms as noninvasive biomarkers for the assessment of liver fibrosis
    • Sep
    • Kovalenko E, Tacke F, Gressner OA, etal. Validation of connective tissue growth factor (CTGF/CCN2) and its gene polymorphisms as noninvasive biomarkers for the assessment of liver fibrosis. J Viral Hepat. Sep 2009; 16(9):612-20.
    • (2009) J Viral Hepat. , vol.16 , Issue.9 , pp. 612-620
    • Kovalenko, E.1    Tacke, F.2    Gressner, O.A.3
  • 104
    • 0013791951 scopus 로고
    • Note on the change of transaminases in the liver and the significance of the transaminase ratio in experimental Tyzzer's disease of mice 1
    • Aug
    • Naiki M, Takagaki Y, Fujiwara K. Note on the change of transaminases in the liver and the significance of the transaminase ratio in experimental Tyzzer's disease of mice 1. Jpn J Exp Med. Aug 1965;35(4):305-9.
    • (1965) Jpn J Exp Med , vol.35 , Issue.4 , pp. 305-309
    • Naiki, M.1    Takagaki, Y.2    Fujiwara, K.3
  • 105
    • 0033834092 scopus 로고    scopus 로고
    • Need for validation of clinical decision aids: Use of the AST/ALT ratio in predicting cirrhosis in chronic hepatitis C 1
    • Sep
    • Imperiale TF, Said AT, Cummings OW, Born LJ. Need for validation of clinical decision aids: use of the AST/ALT ratio in predicting cirrhosis in chronic hepatitis C 1. Am J Gastroenterol. Sep 2000;95(9):2328-32.
    • (2000) Am J Gastroenterol , vol.95 , Issue.9 , pp. 2328-2332
    • Imperiale, T.F.1    Said, A.T.2    Cummings, O.W.3    Born, L.J.4
  • 106
    • 0034099413 scopus 로고    scopus 로고
    • Aspartate aminotransferase: Alanine aminotransferase ratio in chronic hepatitis C infection: Is it a useful predictor of cirrhosis?
    • Apr
    • Park GJ, Lin BP, Ngu MC, Jones DB, Katelaris PH. Aspartate aminotransferase: alanine aminotransferase ratio in chronic hepatitis C infection: is it a useful predictor of cirrhosis? J Gastroenterol Hepatol. Apr 2000; 15(4):386-90.
    • (2000) J Gastroenterol Hepatol. , vol.15 , Issue.4 , pp. 386-390
    • Park, G.J.1    Lin, B.P.2    Ngu, M.C.3    Jones, D.B.4    Katelaris, P.H.5
  • 107
    • 15444376333 scopus 로고    scopus 로고
    • Mildly elevated liver transaminase levels in the asymptomatic patient
    • Mar 15
    • Giboney PT. Mildly elevated liver transaminase levels in the asymptomatic patient. Am Fam Physician. Mar 15, 2005;71(6):1105-10.
    • (2005) Am Fam Physician , vol.71 , Issue.6 , pp. 1105-1110
    • Giboney, P.T.1
  • 108
    • 0042265556 scopus 로고    scopus 로고
    • A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C 1
    • Aug
    • Wai CT, Greenson JK, Fontana RJ, etal. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C 1. Hepatology. Aug 2003;38(2):518-26.
    • (2003) Hepatologyc , vol.38 , Issue.2 , pp. 518-526
    • Wai, C.T.1    Greenson, J.K.2    Fontana, R.J.3
  • 109
    • 34548786091 scopus 로고    scopus 로고
    • Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis C-related fibrosis: A systematic review 5
    • Sep
    • Shaheen AA, Myers RP. Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis C-related fibrosis: a systematic review 5. Hepatology. Sep 2007;46(3): 912-21.
    • (2007) Hepatology , vol.46 , Issue.3 , pp. 912-921
    • Shaheen, A.A.1    Myers, R.P.2
  • 110
    • 79952223130 scopus 로고    scopus 로고
    • Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis: An updated meta-analysis 1
    • Mar
    • Lin ZH, Xin YN, Dong QJ, et al. Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis: an updated meta-analysis 1. Hepatology. Mar 2011;53(3):726-36.
    • (2011) Hepatology , vol.53 , Issue.3 , pp. 726-736
    • Lin, Z.H.1    Xin, Y.N.2    Dong, Q.J.3
  • 111
    • 12344267742 scopus 로고    scopus 로고
    • Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C
    • Sep, 23
    • Poynard T, Imbert-Bismut F, Munteanu M, etal. Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C. Comp Hepatol. Sep 2004 23;3(1):8.
    • (2004) Comp Hepatol , vol.3 , Issue.1 , pp. 8
    • Poynard, T.1    Imbert-Bismut, F.2    Munteanu, M.3
  • 112
    • 33644525960 scopus 로고    scopus 로고
    • FibroScan and FibroTest to assess liver fibrosis in HCV with normal aminotransferases 1
    • Feb
    • Castera L, Foucher J, Bertet J, Couzigou P, de Ledinghen V. FibroScan and FibroTest to assess liver fibrosis in HCV with normal aminotransferases 1. Hepatology. Feb 2006;43(2):373-4.
    • (2006) Hepatology , vol.43 , Issue.2 , pp. 373-374
    • Castera, L.1    Foucher, J.2    Bertet, J.3    Couzigou, P.4    de Ledinghen, V.5
  • 113
    • 0037471273 scopus 로고    scopus 로고
    • Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients 4
    • Mar 28
    • Myers RP, Benhamou Y, Imbert-Bismut F, etal. Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients 4. AIDS. Mar 28, 2003;17(5):721-5.
    • (2003) AIDS , vol.17 , Issue.5 , pp. 721-725
    • Myers, R.P.1    Benhamou, Y.2    Imbert-Bismut, F.3
  • 114
    • 0037371363 scopus 로고    scopus 로고
    • Validation of the FibroTest biochemical markers score in assessing liver fibrosis in hepatitis C patients 1
    • Mar
    • Rossi E, Adams L, Prins A, etal. Validation of the FibroTest biochemical markers score in assessing liver fibrosis in hepatitis C patients 1. Clin Chem. Mar 2003;49(3):450-4.
    • (2003) Clin Chem , vol.49 , Issue.3 , pp. 450-454
    • Rossi, E.1    Adams, L.2    Prins, A.3
  • 115
    • 29344436212 scopus 로고    scopus 로고
    • Diagnostic accuracy of the fibrotest in hemodialysis and renal transplant patients with chronic hepatitis C virus 1
    • Dec 15
    • Varaut A, Fontaine H, Serpaggi J, etal. Diagnostic accuracy of the fibrotest in hemodialysis and renal transplant patients with chronic hepatitis C virus 1. Transplantation. Dec 15, 2005;80(11):1550-5.
    • (2005) Transplantation , vol.80 , Issue.11 , pp. 1550-1555
    • Varaut, A.1    Fontaine, H.2    Serpaggi, J.3
  • 116
    • 33645968969 scopus 로고    scopus 로고
    • Progression of liver fibrosis among injection drug users with chronic hepatitis C 1
    • Apr
    • Wilson LE, Torbenson M, Astemborski J, etal. Progression of liver fibrosis among injection drug users with chronic hepatitis C 1. Hepatology. Apr 2006;43(4):788-95.
    • (2006) Hepatology , vol.43 , Issue.4 , pp. 788-795
    • Wilson, L.E.1    Torbenson, M.2    Astemborski, J.3
  • 117
    • 33644501186 scopus 로고    scopus 로고
    • Noninvasive measures of liver fibrosis 4
    • Feb
    • Rockey DC, Bissell DM. Noninvasive measures of liver fibrosis 4. Hepatology. Feb 2006;43(2 Suppl 1):S113-20.
    • (2006) Hepatology , vol.43 , Issue.2 SUPPL. 1
    • Rockey, D.C.1    Bissell, D.M.2
  • 118
    • 32144449983 scopus 로고    scopus 로고
    • A novel panel of blood markers to assess the degree of liver fibrosis
    • Dec
    • Cales P, Oberti F, Michalak S, etal. A novel panel of blood markers to assess the degree of liver fibrosis. Hepatology. Dec 2005;42(6):1373-81.
    • (2005) Hepatology , vol.42 , Issue.6 , pp. 1373-1381
    • Cales, P.1    Oberti, F.2    Michalak, S.3
  • 119
    • 34047173013 scopus 로고    scopus 로고
    • Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C
    • May
    • Leroy V, Hilleret MN, Sturm N, etal. Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C. J Hepatol. May 2007;46(5):775-82.
    • (2007) J Hepatol , vol.46 , Issue.5 , pp. 775-782
    • Leroy, V.1    Hilleret, M.N.2    Sturm, N.3
  • 121
    • 56149116412 scopus 로고    scopus 로고
    • Prediction of clinical outcomes in primary biliary cirrhosis by serum enhanced liver fibrosis assay 1
    • Nov
    • Mayo MJ, Parkes J, ms-Huet B, et al. Prediction of clinical outcomes in primary biliary cirrhosis by serum enhanced liver fibrosis assay 1. Hepatology. Nov 2008;48(5):1549-57.
    • (2008) Hepatology , vol.48 , Issue.5 , pp. 1549-1557
    • Mayo, M.J.1    Parkes, J.2    Ms-Huet, B.3
  • 122
    • 59849117801 scopus 로고    scopus 로고
    • Performance of ELF serum markers in predicting fibrosis stage in pediatric non-alcoholic fatty liver disease
    • Jan
    • Nobili V, Parkes J, Bottazzo G, et al. Performance of ELF serum markers in predicting fibrosis stage in pediatric non-alcoholic fatty liver disease. Gastroenterology. Jan 2009;136(1):160-7.
    • (2009) Gastroenterology , vol.136 , Issue.1 , pp. 160-167
    • Nobili, V.1    Parkes, J.2    Bottazzo, G.3
  • 123
    • 84857866996 scopus 로고    scopus 로고
    • Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: A systematic review and economic evaluation
    • Feb
    • Stevenson M, Lloyd-Jones M, Morgan MY, Wong R. Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation. Health Technol Assess. Feb 2012;16(4):1-174.
    • (2012) Health Technol Assess , vol.16 , Issue.4 , pp. 1-174
    • Stevenson, M.1    Lloyd-Jones, M.2    Morgan, M.Y.3    Wong, R.4
  • 124
    • 33745615815 scopus 로고    scopus 로고
    • Classification of osteoarthritis biomarkers: A proposed approach
    • Aug
    • Bauer DC, Hunter DJ, Abramson SB, et al. Classification of osteoarthritis biomarkers: a proposed approach. Osteoarthritis Cartilage. Aug 2006; 14(8):723-7.
    • (2006) Osteoarthritis Cartilage , vol.14 , Issue.8 , pp. 723-727
    • Bauer, D.C.1    Hunter, D.J.2    Abramson, S.B.3
  • 125
    • 42949130108 scopus 로고    scopus 로고
    • Diagnosis and quantitation of fibrosis
    • May
    • Manning DS, Afdhal NH. Diagnosis and quantitation of fibrosis. Gastroenterology. May 2008;134(6):1670-81.
    • (2008) Gastroenterology , vol.134 , Issue.6 , pp. 1670-1681
    • Manning, D.S.1    Afdhal, N.H.2
  • 126
    • 40049097359 scopus 로고    scopus 로고
    • Liver cirrhosis
    • Mar 8
    • Schuppan D, Afdhal NH. Liver cirrhosis. Lancet. Mar 8, 2008;371(9615): 838-51.
    • (2008) Lancet , vol.371 , Issue.9615 , pp. 838-851
    • Schuppan, D.1    Afdhal, N.H.2
  • 127
    • 78751581610 scopus 로고    scopus 로고
    • Clinical proteomics for liver disease: A promising approach for discovery of novel biomarkers
    • Uto H, Kanmura S, Takami Y, Tsubouchi H. Clinical proteomics for liver disease: a promising approach for discovery of novel biomarkers. Proteome Sci. 2010;8:70.
    • (2010) Proteome Sci. , vol.8 , pp. 70
    • Uto, H.1    Kanmura, S.2    Takami, Y.3    Tsubouchi, H.4


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