Activation of adenosine receptor A2A increases HSC proliferation and inhibits death and senescence by down-regulation of p53 and Rb

Frontiers in Pharmacology

Volumn 5 APR, Issue , 2014, Pages

  Ahsan, Md Kaimul ^a   Mehal, Wajahat Z ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine receptors; Apoptosis; Hepatic stellate cells; Liver fibrosis; Senescence

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; 8 BROMO CYCLIC AMP; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2A RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN P53; RAC1 PROTEIN; RETINOBLASTOMA PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRDU ASSAY; CELL ACTIVATION; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; LIVER FIBROSIS; LX2 CELL LINE; MALE; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; SENESCENCE; STELLATE CELL;

EID: 84901029696     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2014.00069     Document Type: Article

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