-
1
-
-
0042121374
-
Barrier function of the skin: «la raison d'être» of the epidermis
-
K.C. Madison Barrier function of the skin: «la raison d'être» of the epidermis J Invest Dermatol 121 2003 231 241
-
(2003)
J Invest Dermatol
, vol.121
, pp. 231-241
-
-
Madison, K.C.1
-
2
-
-
67649838095
-
Filaggrin in the frontline: Role in skin barrier function and disease
-
A. Sandilands, C. Sutherland, A.D. Irvine, and W.H. McLean Filaggrin in the frontline: Role in skin barrier function and disease J Cell Sci 122 2009 1285 1294
-
(2009)
J Cell Sci
, vol.122
, pp. 1285-1294
-
-
Sandilands, A.1
Sutherland, C.2
Irvine, A.D.3
McLean, W.H.4
-
3
-
-
0017340363
-
Purification and characterization of a basic protein from the stratum corneum of mammalian epidermis
-
B.A. Dale Purification and characterization of a basic protein from the stratum corneum of mammalian epidermis Biochim Biophys Acta 491 1977 193 204
-
(1977)
Biochim Biophys Acta
, vol.491
, pp. 193-204
-
-
Dale, B.A.1
-
4
-
-
0019404525
-
Characterization of a class of cationic proteins that specifically interact with intermediate filaments
-
P.M. Steinert, J.S. Cantieri, D.C. Teller, J.D. Lonsdale-Eccles, and B.A. Dale Characterization of a class of cationic proteins that specifically interact with intermediate filaments Proc Natl Acad Sci USA 78 1981 4097 4101
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 4097-4101
-
-
Steinert, P.M.1
Cantieri, J.S.2
Teller, D.C.3
Lonsdale-Eccles, J.D.4
Dale, B.A.5
-
5
-
-
84873333462
-
The multifunctional role of filaggrin in allergic skin disease
-
M.A. McAleer, and A.D. Irvine The multifunctional role of filaggrin in allergic skin disease J Allergy Clin Immunol 131 2013 280 291
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 280-291
-
-
McAleer, M.A.1
Irvine, A.D.2
-
7
-
-
0033620472
-
Bricks and mortar of the epidermal barrier
-
Z. Nemes, and P.M. Steinert Bricks and mortar of the epidermal barrier Exp Mol Med 31 1999 5 19
-
(1999)
Exp Mol Med
, vol.31
, pp. 5-19
-
-
Nemes, Z.1
Steinert, P.M.2
-
8
-
-
0021796108
-
Ionic calcium reservoirs in mammalian epidermis: Ultrastructural localization by ion-capture cytochemistry
-
G.K. Menon, S. Grayson, and P.M. Elias Ionic calcium reservoirs in mammalian epidermis: Ultrastructural localization by ion-capture cytochemistry J Invest Dermatol 84 1985 508 512
-
(1985)
J Invest Dermatol
, vol.84
, pp. 508-512
-
-
Menon, G.K.1
Grayson, S.2
Elias, P.M.3
-
9
-
-
0026594780
-
Calcium and potassium are important regulators of barrier homeostasis in murine epidermis
-
S.H. Lee, P.M. Elias, E. Proksch, G.K. Menon, M. Mao-Quiang, and K.R. Feingold Calcium and potassium are important regulators of barrier homeostasis in murine epidermis J Clin Invest 89 1992 530 538
-
(1992)
J Clin Invest
, vol.89
, pp. 530-538
-
-
Lee, S.H.1
Elias, P.M.2
Proksch, E.3
Menon, G.K.4
Mao-Quiang, M.5
Feingold, K.R.6
-
10
-
-
84856597563
-
Filaggrin mutations and atopy: Consequences for future therapeutics
-
J. Heimall, and J.M. Spergel Filaggrin mutations and atopy: Consequences for future therapeutics Expert Rev Clin Immunol 8 2012 189 197
-
(2012)
Expert Rev Clin Immunol
, vol.8
, pp. 189-197
-
-
Heimall, J.1
Spergel, J.M.2
-
11
-
-
0034794332
-
Assembly of the epidermal cornified cell envelope
-
A. Kalinin, L.N. Marekov, and P.M. Steinert Assembly of the epidermal cornified cell envelope J Cell Sci 114 2001 3069 3070
-
(2001)
J Cell Sci
, vol.114
, pp. 3069-3070
-
-
Kalinin, A.1
Marekov, L.N.2
Steinert, P.M.3
-
12
-
-
0036715005
-
Epithelial barrier function: Assembly and structural features of the cornified cell envelope
-
A.E. Kalinin, A.V. Kajava, and P.M. Steinert Epithelial barrier function: Assembly and structural features of the cornified cell envelope Bioessays 24 2002 789 800
-
(2002)
Bioessays
, vol.24
, pp. 789-800
-
-
Kalinin, A.E.1
Kajava, A.V.2
Steinert, P.M.3
-
13
-
-
17144371855
-
The cornified envelope: A model of cell death in the skin
-
E. Candi, R. Schmidt, and G. Melino The cornified envelope: A model of cell death in the skin Nat Rev Mol Cell Biol 6 2005 328 340
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 328-340
-
-
Candi, E.1
Schmidt, R.2
Melino, G.3
-
14
-
-
1342325502
-
Moisturization and skin barrier function
-
A.V. Rawlings, and C.R. Harding Moisturization and skin barrier function Dermatol Ther 17 Suppl 1 2004 43 48
-
(2004)
Dermatol Ther
, vol.17
, pp. 43-48
-
-
Rawlings, A.V.1
Harding, C.R.2
-
15
-
-
84856901014
-
One remarkable molecule: Filaggrin
-
S.J. Brown, and W.H. McLean One remarkable molecule: Filaggrin J Invest Dermatol 132 2012 751 762
-
(2012)
J Invest Dermatol
, vol.132
, pp. 751-762
-
-
Brown, S.J.1
McLean, W.H.2
-
16
-
-
79959249198
-
Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function
-
R. Gruber, P.M. Elias, D. Crumrine, T.-K. Lin, J.M. Brandner, and J.-P. Hachem Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function Am J Pathol 178 2011 2252 2263
-
(2011)
Am J Pathol
, vol.178
, pp. 2252-2263
-
-
Gruber, R.1
Elias, P.M.2
Crumrine, D.3
Lin, T.-K.4
Brandner, J.M.5
Hachem, J.-P.6
-
17
-
-
84876572438
-
Skin pH: From basic science to basic skin care
-
S.M. Ali, and G. Yosipovitch Skin pH: From basic science to basic skin care Acta Derm Venereol 93 2013 261 267
-
(2013)
Acta Derm Venereol
, vol.93
, pp. 261-267
-
-
Ali, S.M.1
Yosipovitch, G.2
-
18
-
-
78650256687
-
Increased sensitivity of histidinemic mice to UVB radiation suggests a crucial role of endogenous urocanic acid in photoprotection
-
C. Barresi, C. Stremnitzer, V. Mlitz, S. Kezic, A. Kammeyer, and M. Ghannadan Increased sensitivity of histidinemic mice to UVB radiation suggests a crucial role of endogenous urocanic acid in photoprotection J Invest Dermatol 131 2011 188 194
-
(2011)
J Invest Dermatol
, vol.131
, pp. 188-194
-
-
Barresi, C.1
Stremnitzer, C.2
Mlitz, V.3
Kezic, S.4
Kammeyer, A.5
Ghannadan, M.6
-
19
-
-
0026650941
-
Immunosuppression by ultraviolet B radiation: Initiation by urocanic acid
-
F.P. Noonan, and E.C. de Fabo Immunosuppression by ultraviolet B radiation: Initiation by urocanic acid Immunol Today 13 1992 250 254
-
(1992)
Immunol Today
, vol.13
, pp. 250-254
-
-
Noonan, F.P.1
De Fabo, E.C.2
-
20
-
-
33751222269
-
Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor
-
J.P. Walterscheid, D.X. Nghiem, N. Kazimi, L.K. Nutt, D.J. McConkey, and M. Norval Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor Proc Natl Acad Sci USA 103 2006 1742 1745
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1742-1745
-
-
Walterscheid, J.P.1
Nghiem, D.X.2
Kazimi, N.3
Nutt, L.K.4
McConkey, D.J.5
Norval, M.6
-
21
-
-
80053517839
-
Filaggrin mutations associated with skin and allergic diseases
-
A.D. Irvine, W.H.I. McLean, and D.Y.M. Leung Filaggrin mutations associated with skin and allergic diseases N Engl J Med 365 2011 1315 1327
-
(2011)
N Engl J Med
, vol.365
, pp. 1315-1327
-
-
Irvine, A.D.1
McLean, W.H.I.2
Leung, D.Y.M.3
-
22
-
-
84862793140
-
Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency
-
e1
-
S. Kezic, G.M. O'Regan, R. Lutter, I. Jakasa, E.S. Koster, and S. Saunders Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency J Allergy Clin Immunol 129 2012 1031 1039 e1
-
(2012)
J Allergy Clin Immunol
, vol.129
, pp. 1031-1039
-
-
Kezic, S.1
O'Regan, G.M.2
Lutter, R.3
Jakasa, I.4
Koster, E.S.5
Saunders, S.6
-
23
-
-
0029932799
-
Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex («epidermal differentiation complex») on human chromosome 1q21
-
D. Mischke, B.P. Korge, I. Marenholz, A. Volz, and A. Ziegler Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex («epidermal differentiation complex») on human chromosome 1q21 J Invest Dermatol 106 1996 989 992
-
(1996)
J Invest Dermatol
, vol.106
, pp. 989-992
-
-
Mischke, D.1
Korge, B.P.2
Marenholz, I.3
Volz, A.4
Ziegler, A.5
-
24
-
-
0027058170
-
Characterization of the human epidermal profilaggrin gene. Genomic organization and identification of an S-100-like calcium binding domain at the amino terminus
-
R.B. Presland, P.V. Haydock, P. Fleckman, W. Nirunsuksiri, and B.A. Dale Characterization of the human epidermal profilaggrin gene. Genomic organization and identification of an S-100-like calcium binding domain at the amino terminus J Biol Chem 267 1992 23772 23781
-
(1992)
J Biol Chem
, vol.267
, pp. 23772-23781
-
-
Presland, R.B.1
Haydock, P.V.2
Fleckman, P.3
Nirunsuksiri, W.4
Dale, B.A.5
-
25
-
-
0028896390
-
Characterization of two distinct calcium-binding sites in the amino-terminus of human profilaggrin
-
R.B. Presland, J.A. Bassuk, J.R. Kimball, and B.A. Dale Characterization of two distinct calcium-binding sites in the amino-terminus of human profilaggrin J Invest Dermatol 104 1995 218 223
-
(1995)
J Invest Dermatol
, vol.104
, pp. 218-223
-
-
Presland, R.B.1
Bassuk, J.A.2
Kimball, J.R.3
Dale, B.A.4
-
26
-
-
84866427480
-
Regulatory role for the profilaggrin N-terminal domain in epidermal homeostasis
-
S. Aho, C.R. Harding, J.M. Lee, H. Meldrum, and C.A. Bosko Regulatory role for the profilaggrin N-terminal domain in epidermal homeostasis J Invest Dermatol 132 2012 2376 2385
-
(2012)
J Invest Dermatol
, vol.132
, pp. 2376-2385
-
-
Aho, S.1
Harding, C.R.2
Lee, J.M.3
Meldrum, H.4
Bosko, C.A.5
-
27
-
-
0031784191
-
Translocation of profilaggrin N-terminal domain into keratinocyte nuclei with fragmented DNA in normal human skin and loricrin keratoderma
-
A. Ishida-Yamamoto, H. Takahashi, R.B. Presland, B.A. Dale, and H. Iizuka Translocation of profilaggrin N-terminal domain into keratinocyte nuclei with fragmented DNA in normal human skin and loricrin keratoderma Lab Invest 78 1998 1245 1253
-
(1998)
Lab Invest
, vol.78
, pp. 1245-1253
-
-
Ishida-Yamamoto, A.1
Takahashi, H.2
Presland, R.B.3
Dale, B.A.4
Iizuka, H.5
-
28
-
-
84858285530
-
Interaction of the profilaggrin N-terminal domain with loricrin in human cultured keratinocytes and epidermis
-
K. Yoneda, T. Nakagawa, O.T. Lawrence, J. Huard, T. Demitsu, and Y. Kubota Interaction of the profilaggrin N-terminal domain with loricrin in human cultured keratinocytes and epidermis J Invest Dermatol 132 2012 1206 1214
-
(2012)
J Invest Dermatol
, vol.132
, pp. 1206-1214
-
-
Yoneda, K.1
Nakagawa, T.2
Lawrence, O.T.3
Huard, J.4
Demitsu, T.5
Kubota, Y.6
-
29
-
-
33644622891
-
Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris
-
F.J.D. Smith, A.D. Irvine, A. Terron-Kwiatkowski, A. Sandilands, L.E. Campbell, and Y. Zhao Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris Nat Genet 38 2006 337 342
-
(2006)
Nat Genet
, vol.38
, pp. 337-342
-
-
Smith, F.J.D.1
Irvine, A.D.2
Terron-Kwiatkowski, A.3
Sandilands, A.4
Campbell, L.E.5
Zhao, Y.6
-
30
-
-
79959724237
-
Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations
-
H. Chen, J.E. Common, R.L. Haines, A. Balakrishnan, S.J. Brown, and C.S. Goh Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations Br J Dermatol 165 2011 106 114
-
(2011)
Br J Dermatol
, vol.165
, pp. 106-114
-
-
Chen, H.1
Common, J.E.2
Haines, R.L.3
Balakrishnan, A.4
Brown, S.J.5
Goh, C.S.6
-
32
-
-
84864045498
-
Impact of filaggrin mutations on Raman spectra and biophysical properties of the stratum corneum in mild to moderate atopic dermatitis
-
V. Mlitz, J. Latreille, S. Gardinier, R. Jdid, Y. Drouault, and P. Hufnagl Impact of filaggrin mutations on Raman spectra and biophysical properties of the stratum corneum in mild to moderate atopic dermatitis J Eur Acad Dermatol Venereol 26 2012 983 990
-
(2012)
J Eur Acad Dermatol Venereol
, vol.26
, pp. 983-990
-
-
Mlitz, V.1
Latreille, J.2
Gardinier, S.3
Jdid, R.4
Drouault, Y.5
Hufnagl, P.6
-
33
-
-
79952759315
-
Full sequencing of the FLG gene in Italian patients with atopic eczema: Evidence of new mutations, but lack of an association
-
R. Cascella, V. Foti Cuzzola, T. Lepre, E. Galli, V. Moschese, and L. Chini Full sequencing of the FLG gene in Italian patients with atopic eczema: Evidence of new mutations, but lack of an association J Invest Dermatol 131 2011 982 984
-
(2011)
J Invest Dermatol
, vol.131
, pp. 982-984
-
-
Cascella, R.1
Foti Cuzzola, V.2
Lepre, T.3
Galli, E.4
Moschese, V.5
Chini, L.6
-
34
-
-
77955716350
-
Knockdown of filaggrin impairs diffusion barrier function and increases UV sensitivity in a human skin model
-
M. Mildner, J. Jin, L. Eckhart, S. Kezic, F. Gruber, and C. Barresi Knockdown of filaggrin impairs diffusion barrier function and increases UV sensitivity in a human skin model J Invest Dermatol 130 2010 2286 2294
-
(2010)
J Invest Dermatol
, vol.130
, pp. 2286-2294
-
-
Mildner, M.1
Jin, J.2
Eckhart, L.3
Kezic, S.4
Gruber, F.5
Barresi, C.6
-
35
-
-
84869144332
-
Skin barrier abnormality caused by filaggrin (FLG) mutations is associated with increased serum 25-hydroxyvitamin D concentrations
-
e2
-
J.P. Thyssen, B. Thuesen, C. Huth, M. Standl, C.G. Carson, and J. Heinrich Skin barrier abnormality caused by filaggrin (FLG) mutations is associated with increased serum 25-hydroxyvitamin D concentrations J Allergy Clin Immunol 130 2012 1204 1207 e2
-
(2012)
J Allergy Clin Immunol
, vol.130
, pp. 1204-1207
-
-
Thyssen, J.P.1
Thuesen, B.2
Huth, C.3
Standl, M.4
Carson, C.G.5
Heinrich, J.6
-
36
-
-
0021987007
-
Ichthyosis vulgaris: Identification of a defect in synthesis of filaggrin correlated with an absence of keratohyaline granules
-
V.P. Sybert, B.A. Dale, and K.A. Holbrook Ichthyosis vulgaris: Identification of a defect in synthesis of filaggrin correlated with an absence of keratohyaline granules J Invest Dermatol 84 1985 191 194
-
(1985)
J Invest Dermatol
, vol.84
, pp. 191-194
-
-
Sybert, V.P.1
Dale, B.A.2
Holbrook, K.A.3
-
37
-
-
0037291337
-
Changes in environmental humidity affect the water-holding property of the stratum corneum and its free amino acid content, and the expression of filaggrin in the epidermis of hairless mice
-
C. Katagiri, J. Sato, J. Nomura, and M. Denda Changes in environmental humidity affect the water-holding property of the stratum corneum and its free amino acid content, and the expression of filaggrin in the epidermis of hairless mice J Dermatol Sci 31 2003 29 35
-
(2003)
J Dermatol Sci
, vol.31
, pp. 29-35
-
-
Katagiri, C.1
Sato, J.2
Nomura, J.3
Denda, M.4
-
38
-
-
84555162348
-
Filaggrin loss-of-function mutation R501X and 22824 carrier status is associated with fissured skin on the hands: Results from a cross-sectional population study
-
J.P. Thyssen, K. Ross-Hansen, J.D. Johansen, C. Zachariae, B.C. Carlsen, and A. Linneberg Filaggrin loss-of-function mutation R501X and 22824 carrier status is associated with fissured skin on the hands: Results from a cross-sectional population study Br J Dermatol 166 2012 46 53
-
(2012)
Br J Dermatol
, vol.166
, pp. 46-53
-
-
Thyssen, J.P.1
Ross-Hansen, K.2
Johansen, J.D.3
Zachariae, C.4
Carlsen, B.C.5
Linneberg, A.6
-
39
-
-
41549117117
-
Filaggrin null mutations and childhood atopic eczema: A population-based case-control study
-
e3
-
S.J. Brown, C.L. Relton, H. Liao, Y. Zhao, A. Sandilands, and I.J. Wilson Filaggrin null mutations and childhood atopic eczema: A population-based case-control study J Allergy Clin Immunol 121 2008 940 946 e3
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 940-946
-
-
Brown, S.J.1
Relton, C.L.2
Liao, H.3
Zhao, Y.4
Sandilands, A.5
Wilson, I.J.6
-
40
-
-
84857036246
-
Skin barrier disruption: A requirement for allergen sensitization?
-
A. De Benedetto, A. Kubo, and L.A. Beck Skin barrier disruption: A requirement for allergen sensitization? J Invest Dermatol 132 2012 949 963
-
(2012)
J Invest Dermatol
, vol.132
, pp. 949-963
-
-
De Benedetto, A.1
Kubo, A.2
Beck, L.A.3
-
41
-
-
2342591290
-
Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003
-
S.G.O. Johansson, T. Bieber, R. Dahl, P.S. Friedmann, B.Q. Lanier, and R.F. Lockey Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003 J Allergy Clin Immunol 113 2004 832 836
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 832-836
-
-
Johansson, S.G.O.1
Bieber, T.2
Dahl, R.3
Friedmann, P.S.4
Lanier, B.Q.5
Lockey, R.F.6
-
42
-
-
79953211122
-
The atopic march: Progression from atopic dermatitis to allergic rhinitis and asthma
-
T. Zheng, J. Yu, M.H. Oh, and Z. Zhu The atopic march: Progression from atopic dermatitis to allergic rhinitis and asthma Allergy Asthma Immunol Res 3 2011 67 73
-
(2011)
Allergy Asthma Immunol Res
, vol.3
, pp. 67-73
-
-
Zheng, T.1
Yu, J.2
Oh, M.H.3
Zhu, Z.4
-
43
-
-
0346063806
-
Atopic dermatitis and the atopic march
-
J.M. Spergel, and A.S. Paller Atopic dermatitis and the atopic march J Allergy Clin Immunol 112 2003 S118 S127
-
(2003)
J Allergy Clin Immunol
, vol.112
, pp. S118-S127
-
-
Spergel, J.M.1
Paller, A.S.2
-
44
-
-
77956537367
-
The role of food allergy in the atopic march
-
K.J. Allen, and S.C. Dharmage The role of food allergy in the atopic march Clin Exp Allergy 40 2010 1439 1441
-
(2010)
Clin Exp Allergy
, vol.40
, pp. 1439-1441
-
-
Allen, K.J.1
Dharmage, S.C.2
-
45
-
-
33645399288
-
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis
-
C.N.A. Palmer, A.D. Irvine, A. Terron-Kwiatkowski, Y. Zhao, H. Liao, and S.P. Lee Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis Nat Genet 38 2006 441 446
-
(2006)
Nat Genet
, vol.38
, pp. 441-446
-
-
Palmer, C.N.A.1
Irvine, A.D.2
Terron-Kwiatkowski, A.3
Zhao, Y.4
Liao, H.5
Lee, S.P.6
-
46
-
-
0021954377
-
Transepidermal water loss in dry and clinically normal skin in patients with atopic dermatitis
-
Y. Werner, and M. Lindberg Transepidermal water loss in dry and clinically normal skin in patients with atopic dermatitis Acta Derm Venereol 65 1985 102 105
-
(1985)
Acta Derm Venereol
, vol.65
, pp. 102-105
-
-
Werner, Y.1
Lindberg, M.2
-
47
-
-
0029565336
-
Objective assessment of the skin of children affected by atopic dermatitis: A study of pH, capacitance and TEWL in eczematous and clinically uninvolved skin
-
S. Seidenari, and G. Giusti Objective assessment of the skin of children affected by atopic dermatitis: A study of pH, capacitance and TEWL in eczematous and clinically uninvolved skin Acta Derm Venereol 75 1995 429 433
-
(1995)
Acta Derm Venereol
, vol.75
, pp. 429-433
-
-
Seidenari, S.1
Giusti, G.2
-
48
-
-
33847052500
-
Filaggrin mutations strongly predispose to early-onset and extrinsic atopic dermatitis
-
S. Weidinger, E. Rodríguez, C. Stahl, S. Wagenpfeil, N. Klopp, and T. Illig Filaggrin mutations strongly predispose to early-onset and extrinsic atopic dermatitis J Invest Dermatol 127 2007 724 726
-
(2007)
J Invest Dermatol
, vol.127
, pp. 724-726
-
-
Weidinger, S.1
Rodríguez, E.2
Stahl, C.3
Wagenpfeil, S.4
Klopp, N.5
Illig, T.6
-
49
-
-
66749163178
-
A homozygous frameshift mutation in the mouse FLG gene facilitates enhanced percutaneous allergen priming
-
P.G. Fallon, T. Sasaki, A. Sandilands, L.E. Campbell, S.P. Saunders, and N.E. Mangan A homozygous frameshift mutation in the mouse FLG gene facilitates enhanced percutaneous allergen priming Nat Genet 41 2009 602 608
-
(2009)
Nat Genet
, vol.41
, pp. 602-608
-
-
Fallon, P.G.1
Sasaki, T.2
Sandilands, A.3
Campbell, L.E.4
Saunders, S.P.5
Mangan, N.E.6
-
50
-
-
69349088601
-
Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen
-
493.e1
-
M.K. Oyoshi, G.F. Murphy, and R.S. Geha Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen J Allergy Clin Immunol 124 2009 485 493 493.e1
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 485-493
-
-
Oyoshi, M.K.1
Murphy, G.F.2
Geha, R.S.3
-
51
-
-
84861703829
-
Altered stratum corneum barrier and enhanced percutaneous immune responses in filaggrin-null mice
-
e6
-
H. Kawasaki, K. Nagao, A. Kubo, T. Hata, A. Shimizu, and H. Mizuno Altered stratum corneum barrier and enhanced percutaneous immune responses in filaggrin-null mice J Allergy Clin Immunol 129 2012 1538 1546 e6
-
(2012)
J Allergy Clin Immunol
, vol.129
, pp. 1538-1546
-
-
Kawasaki, H.1
Nagao, K.2
Kubo, A.3
Hata, T.4
Shimizu, A.5
Mizuno, H.6
-
52
-
-
77955908904
-
Filaggrin null mutations associate with increased frequencies of allergen-specific CD4+ T-helper 2 cells in patients with atopic eczema
-
T. McPherson, V.J. Sherman, A. Aslam, L. Crack, H. Chan, and A. Lloyd-Lavery Filaggrin null mutations associate with increased frequencies of allergen-specific CD4+ T-helper 2 cells in patients with atopic eczema Br J Dermatol 163 2010 544 549
-
(2010)
Br J Dermatol
, vol.163
, pp. 544-549
-
-
McPherson, T.1
Sherman, V.J.2
Aslam, A.3
Crack, L.4
Chan, H.5
Lloyd-Lavery, A.6
-
53
-
-
79952797429
-
Barrier dysfunction caused by environmental proteases in the pathogenesis of allergic diseases
-
T. Takai, and S. Ikeda Barrier dysfunction caused by environmental proteases in the pathogenesis of allergic diseases Allergol Int 60 2011 25 35
-
(2011)
Allergol Int
, vol.60
, pp. 25-35
-
-
Takai, T.1
Ikeda, S.2
-
54
-
-
33749315429
-
Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march
-
I. Marenholz, R. Nickel, F. Rüschendorf, F. Schulz, J. Esparza-Gordillo, and T. Kerscher Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march J Allergy Clin Immunol 118 2006 866 871
-
(2006)
J Allergy Clin Immunol
, vol.118
, pp. 866-871
-
-
Marenholz, I.1
Nickel, R.2
Rüschendorf, F.3
Schulz, F.4
Esparza-Gordillo, J.5
Kerscher, T.6
-
55
-
-
42749094080
-
Filaggrin mutations, atopic eczema, hay fever, and asthma in children
-
e1
-
S. Weidinger, M. O'Sullivan, T. Illig, H. Baurecht, M. Depner, and E. Rodriguez Filaggrin mutations, atopic eczema, hay fever, and asthma in children J Allergy Clin Immunol 121 2008 1203 1209 e1
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 1203-1209
-
-
Weidinger, S.1
O'Sullivan, M.2
Illig, T.3
Baurecht, H.4
Depner, M.5
Rodriguez, E.6
-
56
-
-
79952286850
-
Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy
-
S.J. Brown, Y. Asai, H.J. Cordell, L.E. Campbell, Y. Zhao, and H. Liao Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy J Allergy Clin Immunol 127 2011 661 667
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 661-667
-
-
Brown, S.J.1
Asai, Y.2
Cordell, H.J.3
Campbell, L.E.4
Zhao, Y.5
Liao, H.6
-
58
-
-
42749086738
-
Filaggrin expression in oral, nasal, and esophageal mucosa
-
A. De Benedetto, C.M. Qualia, F.M. Baroody, and L.A. Beck Filaggrin expression in oral, nasal, and esophageal mucosa J Invest Dermatol 128 2008 1594 1597
-
(2008)
J Invest Dermatol
, vol.128
, pp. 1594-1597
-
-
De Benedetto, A.1
Qualia, C.M.2
Baroody, F.M.3
Beck, L.A.4
-
59
-
-
58649107102
-
Proactive therapy of atopic dermatitis - An emerging concept
-
A. Wollenberg, and T. Bieber Proactive therapy of atopic dermatitis - an emerging concept Allergy 64 2009 276 278
-
(2009)
Allergy
, vol.64
, pp. 276-278
-
-
Wollenberg, A.1
Bieber, T.2
-
60
-
-
84864348397
-
Long term treatment concepts and proactive therapy for atopic eczema
-
A. Wollenberg, and L.M. Ehmann Long term treatment concepts and proactive therapy for atopic eczema Ann Dermatol 24 2012 253 260
-
(2012)
Ann Dermatol
, vol.24
, pp. 253-260
-
-
Wollenberg, A.1
Ehmann, L.M.2
-
62
-
-
67649238893
-
Meta-analysis of filaggrin polymorphisms in eczema and asthma: Robust risk factors in atopic disease
-
e7
-
E. Rodríguez, H. Baurecht, E. Herberich, S. Wagenpfeil, S.J. Brown, and H.J. Cordell Meta-analysis of filaggrin polymorphisms in eczema and asthma: Robust risk factors in atopic disease J Allergy Clin Immunol 123 2009 1361 1370 e7
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 1361-1370
-
-
Rodríguez, E.1
Baurecht, H.2
Herberich, E.3
Wagenpfeil, S.4
Brown, S.J.5
Cordell, H.J.6
-
63
-
-
68149112409
-
Filaggrin gene defects and risk of developing allergic sensitisation and allergic disorders: Systematic review and meta-analysis
-
R.A. Van den Oord, and A. Sheikh Filaggrin gene defects and risk of developing allergic sensitisation and allergic disorders: Systematic review and meta-analysis BMJ 339 2009 b2433
-
(2009)
BMJ
, vol.339
, pp. b2433
-
-
Van Den Oord, R.A.1
Sheikh, A.2
-
64
-
-
70349342922
-
Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of: Further delineation of the skin phenotype in a prospective epidemiological study of 792 school children
-
S.J. Brown, C.L. Relton, H. Liao, Y. Zhao, A. Sandilands, and W.H.I. McLean Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of: Further delineation of the skin phenotype in a prospective epidemiological study of 792 school children Br J Dermatol 161 2009 884 889
-
(2009)
Br J Dermatol
, vol.161
, pp. 884-889
-
-
Brown, S.J.1
Relton, C.L.2
Liao, H.3
Zhao, Y.4
Sandilands, A.5
McLean, W.H.I.6
-
65
-
-
59949100258
-
Eczema genetics: Current state of knowledge and future goals
-
S.J. Brown, and W.H.I. McLean Eczema genetics: Current state of knowledge and future goals J Invest Dermatol 129 2009 543 552
-
(2009)
J Invest Dermatol
, vol.129
, pp. 543-552
-
-
Brown, S.J.1
McLean, W.H.I.2
-
66
-
-
43749087602
-
Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema
-
S.J. Brown, A. Sandilands, Y. Zhao, H. Liao, C.L. Relton, and S.J. Meggitt Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema J Invest Dermatol 128 2008 1591 1594
-
(2008)
J Invest Dermatol
, vol.128
, pp. 1591-1594
-
-
Brown, S.J.1
Sandilands, A.2
Zhao, Y.3
Liao, H.4
Relton, C.L.5
Meggitt, S.J.6
-
67
-
-
33847068830
-
Two common loss-of-function mutations within the filaggrin gene predispose for early onset of atopic dermatitis
-
S. Stemmler, Q. Parwez, E. Petrasch-Parwez, J.T. Epplen, and S. Hoffjan Two common loss-of-function mutations within the filaggrin gene predispose for early onset of atopic dermatitis J Invest Dermatol 127 2007 722 724
-
(2007)
J Invest Dermatol
, vol.127
, pp. 722-724
-
-
Stemmler, S.1
Parwez, Q.2
Petrasch-Parwez, E.3
Epplen, J.T.4
Hoffjan, S.5
-
68
-
-
84869142043
-
The persistence of atopic dermatitis and filaggrin (FLG) mutations in a US longitudinal cohort
-
D.J. Margolis, A.J. Apter, J. Gupta, O. Hoffstad, M. Papadopoulos, and L.E. Campbell The persistence of atopic dermatitis and filaggrin (FLG) mutations in a US longitudinal cohort J Allergy Clin Immunol 130 2012 912 917
-
(2012)
J Allergy Clin Immunol
, vol.130
, pp. 912-917
-
-
Margolis, D.J.1
Apter, A.J.2
Gupta, J.3
Hoffstad, O.4
Papadopoulos, M.5
Campbell, L.E.6
-
69
-
-
77953093849
-
Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema
-
J.M. Jungersted, H. Scheer, M. Mempel, H. Baurecht, L. Cifuentes, and J.K. Høgh Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema Allergy 65 2010 911 918
-
(2010)
Allergy
, vol.65
, pp. 911-918
-
-
Jungersted, J.M.1
Scheer, H.2
Mempel, M.3
Baurecht, H.4
Cifuentes, L.5
Høgh, J.K.6
-
70
-
-
41449089071
-
The burden of disease associated with filaggrin mutations: A population-based, longitudinal birth cohort study
-
e9
-
J. Henderson, K. Northstone, S.P. Lee, H. Liao, Y. Zhao, and M. Pembrey The burden of disease associated with filaggrin mutations: A population-based, longitudinal birth cohort study J Allergy Clin Immunol 121 2008 872 877 e9
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 872-877
-
-
Henderson, J.1
Northstone, K.2
Lee, S.P.3
Liao, H.4
Zhao, Y.5
Pembrey, M.6
-
71
-
-
69349102719
-
Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum
-
513.e1-7
-
P.S. Gao, N.M. Rafaels, T. Hand, T. Murray, M. Boguniewicz, and T. Hata Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum J Allergy Clin Immunol 124 2009 507 513 513.e1-7
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 507-513
-
-
Gao, P.S.1
Rafaels, N.M.2
Hand, T.3
Murray, T.4
Boguniewicz, M.5
Hata, T.6
-
72
-
-
46349083170
-
Gene-environment interaction in the onset of eczema in infancy: Filaggrin loss-of-function mutations enhanced by neonatal cat exposure
-
H. Bisgaard, A. Simpson, C.N.A. Palmer, K. Bønnelykke, I. McLean, and S. Mukhopadhyay Gene-environment interaction in the onset of eczema in infancy: Filaggrin loss-of-function mutations enhanced by neonatal cat exposure PLoS Med 5 2008 e131
-
(2008)
PLoS Med
, vol.5
, pp. e131
-
-
Bisgaard, H.1
Simpson, A.2
Palmer, C.N.A.3
Bønnelykke, K.4
McLean, I.5
Mukhopadhyay, S.6
-
73
-
-
70449085067
-
Filaggrin mutations in the onset of eczema, sensitization, asthma, hay fever and the interaction with cat exposure
-
M.L.A. Schuttelaar, M. Kerkhof, M.F. Jonkman, G.H. Koppelman, B. Brunekreef, and J.C. de Jongste Filaggrin mutations in the onset of eczema, sensitization, asthma, hay fever and the interaction with cat exposure Allergy 64 2009 1758 1765
-
(2009)
Allergy
, vol.64
, pp. 1758-1765
-
-
Schuttelaar, M.L.A.1
Kerkhof, M.2
Jonkman, M.F.3
Koppelman, G.H.4
Brunekreef, B.5
De Jongste, J.C.6
-
74
-
-
77952737487
-
Elder siblings enhance the effect of filaggrin mutations on childhood eczema: Results from the 2 birth cohort studies LISAplus and GINIplus
-
e5
-
C. Cramer, E. Link, M. Horster, S. Koletzko, C.-P. Bauer, and D. Berdel Elder siblings enhance the effect of filaggrin mutations on childhood eczema: Results from the 2 birth cohort studies LISAplus and GINIplus J Allergy Clin Immunol 125 2010 1254 1260 e5
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 1254-1260
-
-
Cramer, C.1
Link, E.2
Horster, M.3
Koletzko, S.4
Bauer, C.-P.5
Berdel, D.6
-
75
-
-
37749025593
-
Atopic dermatitis
-
T. Bieber Atopic dermatitis N Engl J Med 358 2008 1483 1494
-
(2008)
N Engl J Med
, vol.358
, pp. 1483-1494
-
-
Bieber, T.1
-
76
-
-
0025083475
-
Assessment of a contact-plate sampling technique and subsequent quantitative bacterial studies in atopic dermatitis
-
R.E. Williams, A.G. Gibson, T.C. Aitchison, R. Lever, and R.M. Mackie Assessment of a contact-plate sampling technique and subsequent quantitative bacterial studies in atopic dermatitis Br J Dermatol 123 1990 493 501
-
(1990)
Br J Dermatol
, vol.123
, pp. 493-501
-
-
Williams, R.E.1
Gibson, A.G.2
Aitchison, T.C.3
Lever, R.4
Mackie, R.M.5
-
77
-
-
78649812469
-
Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus
-
e3
-
H. Miajlovic, P.G. Fallon, A.D. Irvine, and T.J. Foster Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus J Allergy Clin Immunol 126 2010 1184 1190 e3
-
(2010)
J Allergy Clin Immunol
, vol.126
, pp. 1184-1190
-
-
Miajlovic, H.1
Fallon, P.G.2
Irvine, A.D.3
Foster, T.J.4
-
78
-
-
46049112666
-
Defective killing of Staphylococcus aureus in atopic dermatitis is associated with reduced mobilization of human beta-defensin-3
-
K.O. Kisich, C.W. Carspecken, S. Fiéve, M. Boguniewicz, and D.Y. Leung Defective killing of Staphylococcus aureus in atopic dermatitis is associated with reduced mobilization of human beta-defensin-3 J Allergy Clin Immunol 122 2008 62 68
-
(2008)
J Allergy Clin Immunol
, vol.122
, pp. 62-68
-
-
Kisich, K.O.1
Carspecken, C.W.2
Fiéve, S.3
Boguniewicz, M.4
Leung, D.Y.5
-
79
-
-
84873414448
-
Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal α-toxin-induced keratinocyte death
-
e2
-
A.M. Brauweiler, L. Bin, B.E. Kim, M.K. Oyoshi, R.S. Geha, and E. Goleva Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal α-toxin-induced keratinocyte death J Allergy Clin Immunol 131 2013 421 427 e2
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 421-427
-
-
Brauweiler, A.M.1
Bin, L.2
Kim, B.E.3
Oyoshi, M.K.4
Geha, R.S.5
Goleva, E.6
-
80
-
-
84555218087
-
Filaggrin mutations are associated with recurrent skin infection in Singaporean Chinese patients with atopic dermatitis
-
S.C. Cai, H. Chen, W.P. Koh, J.E. Common, H.P. van Bever, and W.H. McLean Filaggrin mutations are associated with recurrent skin infection in Singaporean Chinese patients with atopic dermatitis Br J Dermatol 166 2012 200 203
-
(2012)
Br J Dermatol
, vol.166
, pp. 200-203
-
-
Cai, S.C.1
Chen, H.2
Koh, W.P.3
Common, J.E.4
Van Bever, H.P.5
McLean, W.H.6
-
81
-
-
66049114920
-
Cellular and molecular mechanisms in atopic dermatitis
-
M.K. Oyoshi, R. He, L. Kumar, J. Yoon, and R.S. Geha Cellular and molecular mechanisms in atopic dermatitis Adv Immunol 102 2009 135 226
-
(2009)
Adv Immunol
, vol.102
, pp. 135-226
-
-
Oyoshi, M.K.1
He, R.2
Kumar, L.3
Yoon, J.4
Geha, R.S.5
-
82
-
-
69249148345
-
Cytokine modulation of atopic dermatitis filaggrin skin expression
-
M.D. Howell, B.E. Kim, P. Gao, A.V. Grant, M. Boguniewicz, and A. de Benedetto Cytokine modulation of atopic dermatitis filaggrin skin expression J Allergy Clin Immunol 124 2009 R7 R12
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. R7-R12
-
-
Howell, M.D.1
Kim, B.E.2
Gao, P.3
Grant, A.V.4
Boguniewicz, M.5
De Benedetto, A.6
-
83
-
-
39149098125
-
Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6
-
B.E. Kim, D.Y.M. Leung, M. Boguniewicz, and M.D. Howell Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6 Clin Immunol 126 2008 332 337
-
(2008)
Clin Immunol
, vol.126
, pp. 332-337
-
-
Kim, B.E.1
Leung, D.Y.M.2
Boguniewicz, M.3
Howell, M.D.4
-
84
-
-
84856078713
-
Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect
-
S.J. Brown, K. Kroboth, A. Sandilands, L.E. Campbell, E. Pohler, and S. Kezic Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect J Invest Dermatol 132 2012 98 104
-
(2012)
J Invest Dermatol
, vol.132
, pp. 98-104
-
-
Brown, S.J.1
Kroboth, K.2
Sandilands, A.3
Campbell, L.E.4
Pohler, E.5
Kezic, S.6
-
85
-
-
84874118379
-
DNA methylation of the filaggrin gene adds to the risk of eczema associated with loss-of-function variants
-
A.H. Ziyab, W. Karmaus, J.W. Holloway, H. Zhang, S. Ewart, and S.H. Arshad DNA methylation of the filaggrin gene adds to the risk of eczema associated with loss-of-function variants J Eur Acad Dermatol Venereol 27 2012 e420 e423
-
(2012)
J Eur Acad Dermatol Venereol
, vol.27
, pp. e420-e423
-
-
Ziyab, A.H.1
Karmaus, W.2
Holloway, J.W.3
Zhang, H.4
Ewart, S.5
Arshad, S.H.6
-
86
-
-
49749128448
-
Loss-of-function polymorphisms in the filaggrin gene are associated with an increased susceptibility to chronic irritant contact dermatitis: A case-control study
-
C.M. De Jongh, L. Khrenova, M.M. Verberk, F. Calkoen, F.J.H. van Dijk, and H. Voss Loss-of-function polymorphisms in the filaggrin gene are associated with an increased susceptibility to chronic irritant contact dermatitis: A case-control study Br J Dermatol 159 2008 621 627
-
(2008)
Br J Dermatol
, vol.159
, pp. 621-627
-
-
De Jongh, C.M.1
Khrenova, L.2
Verberk, M.M.3
Calkoen, F.4
Van Dijk, F.J.H.5
Voss, H.6
-
87
-
-
84873197244
-
Impact of atopic dermatitis and loss-of-function mutations in the filaggrin gene on the development of occupational irritant contact dermatitis
-
M.J. Visser, L. Landeck, L.E. Campbell, W.H.I. McLean, S. Weidinger, and F. Calkoen Impact of atopic dermatitis and loss-of-function mutations in the filaggrin gene on the development of occupational irritant contact dermatitis Br J Dermatol 168 2013 326 332
-
(2013)
Br J Dermatol
, vol.168
, pp. 326-332
-
-
Visser, M.J.1
Landeck, L.2
Campbell, L.E.3
McLean, W.H.I.4
Weidinger, S.5
Calkoen, F.6
-
88
-
-
77952684513
-
The association between null mutations in the filaggrin gene and contact sensitization to nickel and other chemicals in the general population
-
J.P. Thyssen, J.D. Johansen, A. Linneberg, T. Menné, N.H. Nielsen, and M. Meldgaard The association between null mutations in the filaggrin gene and contact sensitization to nickel and other chemicals in the general population Br J Dermatol 162 2010 1278 1285
-
(2010)
Br J Dermatol
, vol.162
, pp. 1278-1285
-
-
Thyssen, J.P.1
Johansen, J.D.2
Linneberg, A.3
Menné, T.4
Nielsen, N.H.5
Meldgaard, M.6
-
89
-
-
78650463072
-
Nickel reactivity and filaggrin null mutations - Evaluation of the filaggrin bypass theory in a general population
-
K. Ross-Hansen, T. Menné, J.D. Johansen, B.C. Carlsen, A. Linneberg, and N.H. Nielsen Nickel reactivity and filaggrin null mutations - evaluation of the filaggrin bypass theory in a general population Contact Derm 64 2011 24 31
-
(2011)
Contact Derm
, vol.64
, pp. 24-31
-
-
Ross-Hansen, K.1
Menné, T.2
Johansen, J.D.3
Carlsen, B.C.4
Linneberg, A.5
Nielsen, N.H.6
-
90
-
-
70349339644
-
Filaggrin mutations may confer susceptibility to chronic hand eczema characterized by combined allergic and irritant contact dermatitis
-
S. Molin, S. Vollmer, E.H. Weiss, T. Ruzicka, and J.C. Prinz Filaggrin mutations may confer susceptibility to chronic hand eczema characterized by combined allergic and irritant contact dermatitis Br J Dermatol 161 2009 801 807
-
(2009)
Br J Dermatol
, vol.161
, pp. 801-807
-
-
Molin, S.1
Vollmer, S.2
Weiss, E.H.3
Ruzicka, T.4
Prinz, J.C.5
-
91
-
-
35348869766
-
Loss-of-function mutations in the filaggrin gene and alopecia areata: Strong risk factor for a severe course of disease in patients comorbid for atopic disease
-
R.C. Betz, J. Pforr, A. Flaquer, S. Redler, S. Hanneken, and S. Eigelshoven Loss-of-function mutations in the filaggrin gene and alopecia areata: Strong risk factor for a severe course of disease in patients comorbid for atopic disease J Invest Dermatol 127 2007 2539 2543
-
(2007)
J Invest Dermatol
, vol.127
, pp. 2539-2543
-
-
Betz, R.C.1
Pforr, J.2
Flaquer, A.3
Redler, S.4
Hanneken, S.5
Eigelshoven, S.6
-
92
-
-
36248957531
-
Filaggrin mutations are genetic modifying factors exacerbating X-linked ichthyosis
-
H. Liao, A.J. Waters, D.R. Goudie, D.A. Aitken, G. Graham, and F.J.D. Smith Filaggrin mutations are genetic modifying factors exacerbating X-linked ichthyosis J Invest Dermatol 127 2007 2795 2798
-
(2007)
J Invest Dermatol
, vol.127
, pp. 2795-2798
-
-
Liao, H.1
Waters, A.J.2
Goudie, D.R.3
Aitken, D.A.4
Graham, G.5
Smith, F.J.D.6
-
93
-
-
72649106306
-
Increased pachyonychia congenita severity in patients with concurrent keratin and filaggrin mutations
-
R. Gruber, N.J. Wilson, F.J.D. Smith, D. Grabher, L. Steinwender, and P.O. Fritsch Increased pachyonychia congenita severity in patients with concurrent keratin and filaggrin mutations Br J Dermatol 161 2009 1391 1395
-
(2009)
Br J Dermatol
, vol.161
, pp. 1391-1395
-
-
Gruber, R.1
Wilson, N.J.2
Smith, F.J.D.3
Grabher, D.4
Steinwender, L.5
Fritsch, P.O.6
-
94
-
-
79955892989
-
A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: A cross-sectional study
-
J.P. Thyssen, A. Linneberg, B.C. Carlsen, J.D. Johansen, K. Engkilde, and T. Hansen A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: A cross-sectional study BMJ Open 1 2011 e000062
-
(2011)
BMJ Open
, vol.1
, pp. e000062
-
-
Thyssen, J.P.1
Linneberg, A.2
Carlsen, B.C.3
Johansen, J.D.4
Engkilde, K.5
Hansen, T.6
-
95
-
-
79956019238
-
Filaggrin null mutations are not a protective factor for acne vulgaris
-
J.E.A. Common, S.J. Brown, R.L. Haines, C.S. Goh, H. Chen, and A. Balakrishnan Filaggrin null mutations are not a protective factor for acne vulgaris J Invest Dermatol 131 2011 1378 1380
-
(2011)
J Invest Dermatol
, vol.131
, pp. 1378-1380
-
-
Common, J.E.A.1
Brown, S.J.2
Haines, R.L.3
Goh, C.S.4
Chen, H.5
Balakrishnan, A.6
-
96
-
-
34447580008
-
Filaggrin null alleles are not associated with psoriasis
-
Y. Zhao, A. Terron-Kwiatkowski, H. Liao, S.P. Lee, M.H. Allen, and P.R. Hull Filaggrin null alleles are not associated with psoriasis J Invest Dermatol 127 2007 1878 1882
-
(2007)
J Invest Dermatol
, vol.127
, pp. 1878-1882
-
-
Zhao, Y.1
Terron-Kwiatkowski, A.2
Liao, H.3
Lee, S.P.4
Allen, M.H.5
Hull, P.R.6
-
97
-
-
80053290922
-
The filaggrin null genotypes R501X and 22824 seem not to be associated with psoriasis: Results from general population study and meta-analysis
-
J.P. Thyssen, J.D. Johansen, B.C. Carlsen, A. Linneberg, M. Meldgaard, and P.B. Szecsi The filaggrin null genotypes R501X and 22824 seem not to be associated with psoriasis: Results from general population study and meta-analysis J Eur Acad Dermatol Venereol 26 2012 782 784
-
(2012)
J Eur Acad Dermatol Venereol
, vol.26
, pp. 782-784
-
-
Thyssen, J.P.1
Johansen, J.D.2
Carlsen, B.C.3
Linneberg, A.4
Meldgaard, M.5
Szecsi, P.B.6
-
98
-
-
37749032145
-
Loss-of-function mutations in the filaggrin gene: No contribution to disease susceptibility, but to autoantibody formation against citrullinated peptides in early rheumatoid arthritis
-
U. Hüffmeier, U. Böiers, J. Lascorz, A. Reis, and H. Burkhardt Loss-of-function mutations in the filaggrin gene: No contribution to disease susceptibility, but to autoantibody formation against citrullinated peptides in early rheumatoid arthritis Ann Rheum Dis 67 2008 131 133
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 131-133
-
-
Hüffmeier, U.1
Böiers, U.2
Lascorz, J.3
Reis, A.4
Burkhardt, H.5
-
99
-
-
70450191414
-
Filaggrin loss-of-function variants are associated with atopic comorbidity in pediatric inflammatory bowel disease
-
J. Van Limbergen, R.K. Russell, E.R. Nimmo, Y. Zhao, H. Liao, and H.E. Drummond Filaggrin loss-of-function variants are associated with atopic comorbidity in pediatric inflammatory bowel disease Inflamm Bowel Dis 15 2009 1492 1498
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 1492-1498
-
-
Van Limbergen, J.1
Russell, R.K.2
Nimmo, E.R.3
Zhao, Y.4
Liao, H.5
Drummond, H.E.6
-
100
-
-
33749862108
-
Filaggrin loss-of-function variant contributes to atopic dermatitis risk in the population of Northern Germany
-
A. Ruether, M. Stoll, T. Schwarz, S. Schreiber, and R. Fölster-Holst Filaggrin loss-of-function variant contributes to atopic dermatitis risk in the population of Northern Germany Br J Dermatol 155 2006 1093 1094
-
(2006)
Br J Dermatol
, vol.155
, pp. 1093-1094
-
-
Ruether, A.1
Stoll, M.2
Schwarz, T.3
Schreiber, S.4
Fölster-Holst, R.5
-
101
-
-
66749158517
-
Carrier status for the common R501X and 22824 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort
-
S. Rodriguez, A.J. Hall, R. Granell, W.H. McLean, A.D. Irvine, and C.N. Palmer Carrier status for the common R501X and 22824 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort PLoS ONE 4 2009 e5784
-
(2009)
PLoS ONE
, vol.4
, pp. e5784
-
-
Rodriguez, S.1
Hall, A.J.2
Granell, R.3
McLean, W.H.4
Irvine, A.D.5
Palmer, C.N.6
|