Atopic dermatitis: Update and proposed management algorithm;Actualización en dermatitis atópica. Propuesta de algoritmo de actuación

Actas Dermo-Sifiliograficas

Volumn 104, Issue 1, 2013, Pages 4-16

  Garnacho Saucedo, G ^a   Salido Vallejo, R ^a   Moreno Gimenez J C ^a  

^a HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

Author keywords

Atopic dermatitis; Atopic eczema; Score; Severity; Treatment

Indexed keywords

ALGORITHM; ATOPIC DERMATITIS; DISEASE SEVERITY; REVIEW;

EID: 84873868388     PISSN: 00017310     EISSN: 15782190     Source Type: Journal    
DOI: 10.1016/j.adengl.2012.11.001     Document Type: Short Survey

References (82)

1. J. Schmitt, C.M. Chen, C. Apfelbacher, M. Romanos, I. Lehmann, and O. Herbarth Infant eczema, infant sleeping problems, and mental health at 10 years of age: the prospective birth cohort study LISAplus Allergy 66 2011 404 411
2. S.H. Oh, B.G. Bae, C.O. Park, J.Y. Noh, I.H. Park, and Wu Wh Association of stress with symptoms of atopic dermatitis Acta Derm Venereol 90 2010 582 588
3. H.A. Al Shobaili The impact of childhood atopic dermatitis on the patients' family Pediatr Dermatol 27 2010 618 623
4. J.F. Stalder, S. Barbarot, A. Wollenberg, E.A. Holm, L. De Raeve, and S. Seidenari Patient-Oriented SCORAD (PO-SCORAD): a new self-assessment scale in atopic dermatitis validated in Europe Allergy 66 2011 1114 1121
5. M. Vourc'h-Jourdain, S. Barbarot, A. Taieb, T. Diepgen, M. Ambonati, and V. Durosier Patient-oriented SCORAD: a self-assessment score in atopic dermatitis. A preliminary feasibility study Dermatology 218 2009 246 255
6. S.G. Van Velsen, M.J. Knol, I.M. Haeck, C.A. Bruijnzeel-Koomen, and S.G. Pasmans The Self-administered Eczema Area and Severity Index in children with moderate to severe atopic dermatitis: better estimation of AD body surface area than severity Pediatr Dermatol 27 2010 470 475
7. V.E. Rullo, A. Segato, A. Kirsh, and D. Sole Severity scoring of atopic dermatitis: a comparison of two scoring systems Allergol Immunopathol 36 2008 205 211
8. M.S. Lewis-Jones, A.Y. Finlay, and P.J. Dykes The Infants' Dermatitis Quality of Life Index Br J Dermatol 144 2001 104 110
9. M.S. Lewis-Jones, and A.Y. Finlay The Children's Dermatology Life Quality Index (CDLQI): initial validation and practical use Br J Dermatol 132 1995 942 949
10. J.M. Batchelor, D.J. Grindlay, and H.C. Williams What's new in atopic eczema? An analysis of systematic reviews published in 2008 and 2009 Clin Exp Dermatol 35 2010 823 827
11. H. Saeki, M. Furue, F. Furukawa, M. Hide, M. Ohtsuki, and I. Katayama Guidelines for management of atopic dermatitis J Dermatol 36 2009 563 577
12. A.K. Kienast, and P.H. Hoeger Atopic dermatitis in children: what to do when nothing works G Ital Dermatol Venereol 145 2010 303 308
13. D. Simon Systemic therapy of atopic dermatitis in children and adults Curr Probl Dermatol 41 2011 156 164
14. S. Lofgren, and A. Krol New therapies in pediatric dermatology Curr Opin Pediatr 23 2011 399 402
15. J. Schmitt, C.J. Apfelbacher, and C. Flohr Eczema Clin Evid 05 2011 1716 1757
16. F. Bath-Hextall, F.M. Delamere, and H.C. Williams Dietary exclusions for improving established atopic eczema in adults and children: systematic review Allergy 64 2009 258 264
17. J.C. Moreno Probiotics in dermatology Actas Dermosifiliogr 100 2009 348 350
18. L.B. Van der Aa, W.M. van Aalderen, H.S. Heymans, J. Henk Sillevis Smitt, A.J. Nauta, and L.M. Knippels Synbiotics prevent asthma-like symptoms in infants with atopic dermatitis Allergy 66 2011 170 177
19. M.M. Suárez-Varela, L.G. Alvarez, M.D. Kogan, J.C. Ferrerira, A. Martínez Gimeno, and I. Aguinaga Ontonso Diet and prevalence of atopic eczema in 6 to 7-year-old schoolchildren in Spain: ISAAC phase III J Investig Allergol Clin Immunol 20 2010 469 475
20. L.F. Eichenfield, A. McCollum, and P. Msika The benefits of sunflower oleodistillate (SOD) in pediatric dermatology Pediatr Dermatol 26 2009 669 675
21. T.A. Luger Balancing efficacy and safety in the management of atopic dermatitis: the role of methylprednisolone aceponate J Eur Acad Dermatol Venereol 25 2011 251 258
22. A.C. Devillers, and A.P. Oranje Efficacy and safety of 'wet-wrap' dressings as an intervention treatment in children with severe and/or refractory atopic dermatitis: a critical review of the literatura Br J Dermatol 154 2006 579 585
23. S. Dhar Shoul topical antibacterials be routinely combined with topical steroids in the treatment of atopic dermatitis? Indian J Dermatol Venereol Leprol 71 2005 71 72
24. J.Q. Gonq, L. Lin, T. Lin, F. Hao, F.Q. Zeng, and Z.G. Bi Skin colonization by Staphylococcus aureus in patients with eczema and atopic dermatitis and relevant combined topical therapy: a doublé-blind multicentre randomized controlled trial Br J Dermatol 155 2006 680 687
25. R.E. Williams The antibacterial-corticosteroid combination. What is its role in atopic dermatitis? Am J Clin Dermatol 1 2000 211 215
26. M. Kalavala, and M.A. Dohil Calcineurin inhibitors in pediatric atopic dermatitis: a review of current evidence Am J Clin Dermatol 12 2011 15 24
27. J. Schmitt, L. Kobyletzki, A. Svensson, and C. Apfelbacher Efficacy and tolerability of proactive treatment with topical corticosteroids and calcineurin inhibitors for atopic eczema: systematic review and meta-analysis of randomized controlled trials Br J Dermatol 164 2011 4115 4428
28. A. Torrelo Topical tacrolimus in atopic dermatitis in children Actas Dermosifiliogr 99 Suppl 2 2008 14 18
29. A.D. McCollum, A. Paik, and L.F. Eichenfield The safety and efficacy of tacrolimus ointment in pediatric patients with atopic dermatitis Pediatr Dermatol 27 2010 425 436
30. E. Healy, A. Bentley, C. Fidler, and C. Chambers Cost-effectiveness of tacrolimus ointment in adults and children with moderate and severe atopic dermatitis: twice-weekly maintenance treatment vs. standard twice-daily reactive treatment of exacerbations from a third party payer (U.K. National Health Service) perspective Br J Dermatol 164 2011 387 395
31. C. Taneja, R.J. Antaya, A. Berger, T.S. Marshall, R. Seifeldin, and G. Oster Cost-effectiveness of tacrolimus oinment versus pimecrolius cream in adults with atopic dermatitis J Drugs Dermatol 9 2010 372 376
32. T.S. Housman, A.B. Norton, S.R. Feldman, A.B. Fleischer Jr, E.L. Simpson, and J.M. Hanifin Tacrolimus oinment: utilization patterns in children under age 2 year Dermatol Online J 15 2004 10 12
33. L.P. Yang, and M.P. Curran Spotlight on topical pimecrolimus in pediatric atopic dermatitis Am J Clin Dermatol 11 2010 295 298
34. J.J. Emer, A. Frankel, A. Sohn, and M. Lebwohl A bilateral comparison study of pimecrolimus cream 1% and a topical medical device cream in the treatment of patients with atopic dermatitis J Drugs Dermatol 10 2011 735 743
35. J.T. Huang, A. Rademaker, and A.S. Paller Dilute bleach baths for Staphylococcus aureus colonization in atopic dermatitis to decrease disease severity Arch Dermatol 147 2011 246 247
36. J.T. Huang, M. Abrams, B. Tlougan, A. Rademaker, and A.S. Paller Treatment of Staphylococcus aureus colonization in atopic dermatitis decreases disease severity Pediatrics 123 2009 e808 e814
37. F.E. Craig, E.V. Smith, and H.C. Williams Bleach baths to reduce severity of atopic dermatitis colonized by Staphylococcus Arch Dermatol 146 2010 541 543
38. F.J. Bath-Hextall, A.J. Birnie, J.C. Ravenscroft, and H.C. Williams Interventions to reduce Staphylococcus aureus in the management of atopic eczema: an updated Cochrane review Br J Dermatol 163 2010 12 26
39. T. Gambichler, N. Othlinghaus, N.S. Tomi, T. Holland Letz, S. Boms, and M. Skrygan Medium-dose ultraviolet (UV) A1 vs. narrowband UVB phototherapy in atopic eczema: a randomized crossover study Br J Dermatol 160 2009 652 658
40. S. Tzaneva, H. Kittler, G. Holzer, D. Reljic, M. Weber, and H. Honigsmann 5-Methoxypsoralen plus ultraviolet (UV) A is superior to medium-dose UVA1 in the treatment of severe atopic dermatitis: a randomized crossover trial Br J Dermatol 162 2010 655 660
41. H.J. Byun, H.I. Lee, B. Kim, M.N. Kim, H. Hong, and Y. Choi Full-spectrum light phototherapy for atopic dermatitis Int J Dermatol 50 2011 94 101
42. R.W. McClain, B.A. Yentzer, and S.R. Feldman Comparison of skin concentrations following topical versus oral corticosteroid treatment: reconsidering the treatment of common inflammatory dermatoses J Drugs Dermatol 8 2009 1076 1079
43. W.C. Neves, J. Mayumi, A. Gianini, D. Liuson, and E. Tanaka Rebound phenomenon to systemic corticosteroid in atopic dermatitis Allergol Immunopathol 33 2005 307 311
44. J. Schmitt, N. Schmitt, and M. Meurer Cyclosporin in the treatment of patients with atopic eczema - a systematic review and meta-analysis J Eur Acad Dermatol Venereol 21 2007 606 619
45. S. Haw, M.K. Shin, and C.R. Haw The efficacy and safety of long-term oral cyclosporine treatment for patients with atopic dermatitis Ann Dermatol 22 2010 9 15
46. C. Brandt, V. Pavlovic, A. Radbruch, M. Worm, and R. Baumgrass Low-dose cyclosporine A therapy increases the regulatory T cell population in patients with atopic dermatitis Allergy 64 2009 1588 1596
47. S.G. van Velsen, M.J. Knol, R.L. van Eijk, M.A. de Vroede, T.C. de Wit, and M.G. Lam Bone mineral density in children with moderate to severe atopic dermatitis J Am Acad Dermatol 63 2010 824 831
48. R. Hughes, P. Collins, and S. Rogers Further experience of using azathioprine in the treatment of severe atopic dermatitis Clin Exp Dermatol 33 2008 710 711
49. R.M. Martel, P. Melwani, D. Islas, Y. Peñate, and L. Borrego Safety of azathioprine therapy adjusted to thiopurine methyltransferase activity in the treatment of infantile atopic dermatitis. Report on 7 cases Actas Dermosifiliogr 101 2010 415 420
50. M.E. Schram, E. Roekevisch, M.M. Leeflang, J.D. Bos, J. Schmitt, and P.I. Spuls A randomized trial of methotrexate versus azathioprine for sever atopic eczema J Allergy Clin Immunol 128 2011 353 359
51. M.E. Schram, R.J. Borgonjen, C.M. Bik, J.G. van der Schroeff, J.J. van Everdingen, and Spuls Pl Off-label use of azathioprine in dermatology: a systematic review Arch Dermatol 147 2011 474 488
52. M. Grundmann-Kollmann, M. Podda, F. Ochsendorf, W.H. Boehncke, R. Kaufmann, and T.M. Zollner Mycophenolate mofetil is effective in the treatment of atopic dermatitis Arch Dermatol 137 2001 870 873
53. S.G. Van Velsen, I.M. Haeck, C.A. Bruijnzeel-Koomen, and M.S. de Bruin-Weller First experience with enteric-coated mycophenolate sodium (Myfortic) in severe recalcitrant adult atopic dermatitis: an open label study Br J Dermatol 160 2009 687 691
54. M.L. Murray, and J.B. Cohen Mycophenolate mofetil therapy for moderate to severe atopic dermatitis Clin Exp Dermatol 32 2007 23 27
55. I. Ballester, J.F. Silvestre, M. Pérez-Crespo, and A. Lucas Severe adult atopic dermatitis: treatment with mycophenolate mofetil in 8 patients Actas Dermosifiliogr 100 2009 883 887
56. M. Heller, H.T. Shin, S.J. Orlow, and J.V. Schaffer Mycophenolate mofetil for severe childhood atopic dermatitis: experience in 14 patients Br J Dermatol 157 2007 127 132
57. A. Lyakhovitsky, A. Barzilai, R. Heyman, S. Baum, B. Amichai, and M. Solomon Low-dose methotrexate treatment for moderate-to-severe atopic dermatitis in adults J Eur Acad Dermatol Venereol 24 2010 43 49
58. S.C. Weatherhead, S. Wahie, N.J. Reynolds, and S.J. Meggitt An open label dose ranging study of methotrexate for moderate to severe adult atopic eczema Br J Dermatol 156 2007 346 351
59. V.G. Villarrubia, S. Vidal-Asensi, V. Pérez-Bañasco, J. Cuevas-Santos, and R. Cisterna-Cáncer Lipid nutrition and the epidermal barrier: the connection between immune-mediated inflammatory diseases and peroxisome proliferator-activated receptors, a new therapeutic target in psoriasis and atopic dermatitis Actas Dermosifiliogr 101 2010 585 599
60. R. Behshad, K.D. Cooper, and N.J. Korman A retrospective case series review of the peroxisome proliferator-activated receptor ligand rosiglitazone in the treatment of atopic dermatitis Arch Dermatol 144 2008 84 88
61. H.W. Walling, and B.L. Swick Update on the management of chronic eczema: new approaches and emerging treatment options Clin Cosmet Investig Dermatol 28 2010 99 117
62. D.K. Moul, S.B. Routhouska, M.R. Robinson, and N.J. Korman Alefacept for moderate to severe atopic dermatitis: a pilot study in adults J Am Acad Dermatol 58 2008 984 989
63. D. Simon, S. Hosli, G. Kostylina, N. Yawalkar, and H.U. Simon Anti CD20 (Rituximab) treatment improves atopic eczema J Allergy Clin Immunol 121 2008 122 128
64. A. Nagel, M. Hertl, and R. Eming B-cell-directed therapy for inflammatory skin diseases J Invest Dermatol 129 2009 289 301
65. Amrol D. Anti-immunoglobulin E in the treatment of refractory atopic dermatitis South Med J 103 2010 554 558
66. P.M. Heil, D. Maurer, B. Klein, T. Hultsch, and G. Stingl Omalizumab therapy in atopic dermatitis: depletion of Ig E does not improve the clinical course a randomized, placebo controlled and doublé blind pilot study J Dtsch Dermatol Ges 8 2010 990 998
67. A. Asarch, O. Barak, D.S. Loo, and A.B. Gottlieb Th17 cells: a new therapeutic target in inflammatory dermatoses J Dermatolog Treat 19 2008 318 326
68. S. Jolles, C. Sewell, D. Webster, A. Ryan, B. Heelan, and A. Waite Adjunctive high-dose intravenous immunoglobulin treatment for resistant atopic dermatitis: efficacy and effects on intracellular cytokine levels and CD4 counts Acta Derm Venereol 83 2003 433 437
69. S.J. Jee, J.H. Kim, H.S. Baek, H.B. Lee, and J.W. Oh Long-term efficacy of intravenous immunoglobulin therapy for moderate to severe childhood atopic dermatitis Allergy Asthma Immunol Res 3 2011 89 95
70. T.T. Chang, and S.R. Stevens Atopic dermatitis: the role of recombinant interferon-gamma therapy Am J Clin Dermatol 3 2002 175 183
71. I.G. Jang, J.K. Yang, H.J. Lee, J.Y. Yi, H.O. Kim, and C.W. Kim Clinical improvement and immunohistochemical findings in severe atopic dermatitis treated with interferon gamma J Am Acad Dermatol 42 2000 1033 1040
72. K.L. Hon, M.C. Lam, K.Y. Wong, T.F. Leung, and P.C. Ng Pathophysiology of nocturnal scratching in childhood atopic dermatitis: the role of brain-derived neurotrophic factor and substance P Br J Dermatol 157 2007 922 925
73. P.S. Friedmann, R. Palmer, E. Tan, M. Ogboli, G. Barclay, and K. Hotchkiss A double blind, placebo-controlled trial of montelukast in adult atopic eczema Clin Exp Allergy 37 2007 1536 1540
74. M.S. Ehlayel, A. Bener, and A. Sabbah Montelukast treatment in children with moderately severe atopic dermatitis Eur Ann Allergy Clin Immunol 39 2007 232 236
75. S. Zenker, T. Schuh, and K. Degitz Therapy of pruritus associated with skin diseases with the serotonin receptor antagonist ondansetron J Dtsch Dermatol Ges 1 2003 705 710
76. S. Kawana, Y. Kato, and T. Omi Efficacy of a 5-HT1a-receptor agonist in atopic dermatitis Clin Exp Dermatol 35 2010 835 840
77. F. Malekzad, M. Arbabi, N. Mohtasham, P. Toosi, M. Jaberian, and M. Mohajer Efficacy of oral naltrexone on pruritus in atopic eczema: a double-blind, placebo-controlled study J Eur Acad Dermatol Venereol 23 2009 948 950
78. N.Q. Phan, J.D. Bernhard, T.A. Luger, and S. Ständer Antipruritic treatment with systemic μ-opioid receptor antagonists: a review J Am Acad Dermatol 63 2010 680 688
79. C. Moore, M.S. Ehlayel, J. Junprasert, and R.U. Sorensen Topical sodium cromoglycate in the treatment of moderate to severe atopic dermatitis Ann Allergy Immunol 81 1998 452 458
80. R. Stainer, S. Matthews, S.H. Arschad, S. McDonald, J. Robinson, and C. Schapira Efficacy and acceptability of a new topical skin lotion of sodium cromoglicate (altoderm) in atopic dermatitis in children aged 2-12 year: a double blind, randomized, placebo controlled trial Br J Dermatol 152 2005 334 341
81. R. Vieira Dos Santos, M. Mageri, P. Martus, T. Zuberbier, M.K. Church, and L. Escribano Topical sodium cromoglicate relives allergen and histamine induced dermal pruritus Br J Dermatol 162 2010 674 676
82. L. Businco, and A. Cantani Oral sodium cromoglycate in the management of atopic dermatitis in children Allergy Proc 12 1991 333 338