Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: Further delineation of the skin phenotype in a prospective epidemiological study of 792 school children

British Journal of Dermatology

Volumn 161, Issue 4, 2009, Pages 884-889

  Brown, S J ^a,b   Relton, C L ^b   Liao, H ^d   Zhao, Y ^d   Sandilands, A ^d   McLean, W H I ^d   Cordell, H J ^b   Reynolds, N J ^a,c  

^a ROYAL VICTORIA INFIRMARY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Atopic; Eczema; Filaggrin; Ichthyosis vulgaris; Phenotype

Indexed keywords

FILAGGRIN;

ARTICLE; ATOPIC DERMATITIS; CHILD; CONTROLLED STUDY; DISEASE SEVERITY; ECZEMA; FEMALE; GENE DELETION; GENE FREQUENCY; GENE MUTATION; GENOTYPE PHENOTYPE CORRELATION; HUMAN; ICHTHYOSIS; ICHTHYOSIS VULGARIS; KERATOSIS; KERATOSIS PILARIS; MAJOR CLINICAL STUDY; MALE; NULL ALLELE; PALMAR DERMATOGLYPHICS; PRIORITY JOURNAL; SCHOOL CHILD; SKIN MANIFESTATION; WILD TYPE; XEROSIS;

CHILD; DERMATITIS, ATOPIC; ECZEMA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; ICHTHYOSIS VULGARIS; INTERMEDIATE FILAMENT PROTEINS; MALE; MUTATION; PENETRANCE; PHENOTYPE; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 70349342922     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2009.09339.x     Document Type: Article

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