Filaggrin null mutations associate with increased frequencies of allergen-specific CD4+ T-helper 2 cells in patients with atopic eczema

British Journal of Dermatology

Volumn 163, Issue 3, 2010, Pages 544-549

  McPherson, T ^a,b   Sherman, V J ^a   Aslam, A ^a   Crack, L ^a   Chan, H ^a   Lloyd Lavery, A ^a   Jones, L ^a   Ardern Jones, M ^c   Ogg, G ^a,b  

^a NIHR OXFORD BIOMEDICAL RESEARCH CENTRE   (United Kingdom)

^b CHURCHILL HOSPITAL   (United Kingdom)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

atopic eczema; filaggrin; IgE; tetrameric complexes

Indexed keywords

ALLERGEN; FILAGGRIN; HLA A2 ANTIGEN; INTERLEUKIN 4;

ARTICLE; ATOPIC DERMATITIS; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSPOT ASSAY; GENE FREQUENCY; HUMAN; NULL ALLELE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TH2 CELL;

ADULT; CD4-POSITIVE T-LYMPHOCYTES; ECZEMA; GENETIC PREDISPOSITION TO DISEASE; HLA ANTIGENS; HUMANS; IMMUNITY, CELLULAR; INTERLEUKIN-4; INTERMEDIATE FILAMENT PROTEINS; PHENOTYPE; POLYMERASE CHAIN REACTION; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 77955908904     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2010.09866.x     Document Type: Article

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