Hepatic miR-378 targets p110α and controls glucose and lipid homeostasis by modulating hepatic insulin signalling

Nature Communications

Volumn 5, Issue , 2014, Pages

  Liu, Wei ^a,b   Cao, Hongchao ^a,b   Ye, Cheng ^a,b   Chang, Cunjie ^c   Lu, Minghua ^a,d   Jing, Yanyan ^a,b   Zhang, Duo ^a,b   Yao, Xuan ^a,b   Duan, Zhengjun ^a,b   Xia, Hongfeng ^a,b   Wang, Yu Cheng ^e   Jiang, Jingjing ^f   Liu, Mo Fang ^a,d   Yan, Jun ^c   Ying, Hao ^a,b  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^b BEIJING HOSPITAL   (China)

^c NANJING UNIVERSITY   (China)

^d INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^e Xuhui Central Hospital   (China)

^f FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; LIPID; MICRORNA; MICRORNA 378; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P110; PROTEIN P110ALPHA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; GLUCOSE BLOOD LEVEL; MIRN378 MICRORNA, MOUSE; PIK3CA PROTEIN, MOUSE;

CARBOHYDRATE; GENE EXPRESSION; GLUCOSE; HOMEOSTASIS; INHIBITION; LIPID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HYPERGLYCEMIA; HYPOGLYCEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCKOUT MOUSE; LIPID HOMEOSTASIS; LIPID METABOLISM; LIVER; MALE; METABOLIC REGULATION; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN TARGETING; REFEEDING; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; FATTY LIVER; GENETICS; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HOMEOSTASIS; METABOLISM; MOUSE MUTANT;

MUS;

ANIMALS; BLOOD GLUCOSE; FASTING; FATTY LIVER; GLUCOSE; GLUCOSE INTOLERANCE; HOMEOSTASIS; INSULIN; INSULIN RESISTANCE; LIPID METABOLISM; LIVER; MICE; MICE, KNOCKOUT; MICE, OBESE; MICRORNAS; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION;

EID: 84923382720     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6684     Document Type: Article

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