메뉴 건너뛰기




Volumn 35, Issue 8, 2015, Pages 3566-3581

Mitochondrial ATP-Mg/pi carrier SCaMC-3/Slc25a23 counteracts PARP-1-dependent fall in mitochondrial ATP caused by excitotoxic insults in neurons

Author keywords

ATP Mg Pi carrier; Calcium; Excitotoxicity; Mitochondria; PARP 1; SCaMC 3

Indexed keywords

ADENOSINE TRIPHOSPHATE; ATP MG PI CARRIER PROTEINS, MITOCHONDRIA; CALCIUM BINDING MITOCHONDRIAL SOLUTE CARRIER PROTEIN; CARRIER PROTEIN; KAINIC ACID; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOCHONDRIAL PROTEIN; N METHYL DEXTRO ASPARTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; REACTIVE OXYGEN METABOLITE; SMALL CALCIUM BINDING MITOCHONDRIAL CARRIER PROTEIN; UNCLASSIFIED DRUG; ANTIPORTER; ATP-MG-PI CARRIER PROTEINS, MITOCHONDRIA; CALCIUM; N METHYLASPARTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, MOUSE;

EID: 84923363265     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2702-14.2015     Document Type: Article
Times cited : (49)

References (83)
  • 1
    • 46349104861 scopus 로고    scopus 로고
    • Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity
    • CrossRef Medline
    • Abramov AY, Duchen MR (2008) Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity. Biochim Biophys Acta 1777:953-964. CrossRef Medline.
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 953-964
    • Abramov, A.Y.1    Duchen, M.R.2
  • 2
    • 76749154427 scopus 로고    scopus 로고
    • Impaired mitochondrial bioenergetics determines glutamate-induced delayed calcium deregulation in neurons
    • CrossRef Medline
    • Abramov AY, Duchen MR (2010) Impaired mitochondrial bioenergetics determines glutamate-induced delayed calcium deregulation in neurons. Biochim Biophys Acta 1800:297-304. CrossRef Medline.
    • (2010) Biochim Biophys Acta , vol.1800 , pp. 297-304
    • Abramov, A.Y.1    Duchen, M.R.2
  • 3
    • 77649133016 scopus 로고    scopus 로고
    • NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death
    • CrossRef Medline
    • Alano CC, Garnier P, Ying W, Higashi Y, Kauppinen TM, Swanson RA (2010) NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death. J Neurosci 30:2967-2978. CrossRef Medline.
    • (2010) J Neurosci , vol.30 , pp. 2967-2978
    • Alano, C.C.1    Garnier, P.2    Ying, W.3    Higashi, Y.4    Kauppinen, T.M.5    Swanson, R.A.6
  • 4
    • 0021173692 scopus 로고
    • Kainic-acid-induced seizures: A developmental study
    • Medline
    • Albala BJ, Moshé SL, Okada R (1984) Kainic-acid-induced seizures: a developmental study. Brain Res 315:139-148. Medline.
    • (1984) Brain Res , vol.315 , pp. 139-148
    • Albala, B.J.1    Moshé, S.L.2    Okada, R.3
  • 5
    • 84863676916 scopus 로고    scopus 로고
    • SCaMC-1 like a member of the mitochondrial carrier (MC) family preferentially expressed in testis and localized in mitochondria and chromatoid body
    • CrossRef Medline
    • Amigo I, Traba J, Satrú stegui J, del Arco A (2012) SCaMC-1 like a member of the mitochondrial carrier (MC) family preferentially expressed in testis and localized in mitochondria and chromatoid body. PLoS One 7:e40470. CrossRef Medline.
    • (2012) Plos One , vol.7
    • Amigo, I.1    Traba, J.2    Satrú Stegui, J.3    Del Arco, A.4
  • 6
    • 84875141425 scopus 로고    scopus 로고
    • Glucagon regulation of ox-idative phosphorylation requires an increase in matrix adenine nucleotide content through Ca2+ activation of the mitochondrial ATP-Mg/Pi carrier SCaMC-3
    • CrossRef Medline
    • Amigo I, Traba J, González-Barroso MM, Rueda CB, Fernández M, Rial E, Sánchez A, Satrú stegui J, Del Arco A (2013) Glucagon regulation of ox-idative phosphorylation requires an increase in matrix adenine nucleotide content through Ca2+ activation of the mitochondrial ATP-Mg/Pi carrier SCaMC-3. J Biol Chem 288:7791-7802. CrossRef Medline.
    • (2013) J Biol Chem , vol.288 , pp. 7791-7802
    • Amigo, I.1    Traba, J.2    González-Barroso, M.M.3    Rueda, C.B.4    Fernández, M.5    Rial, E.6    Sánchez, A.7    Satrú Stegui, J.8    Del Arco, A.9
  • 10
    • 0027138213 scopus 로고
    • Mechanism and regulation of the mitochondrial ATPMg/ P(I) carrier
    • CrossRef Medline
    • Aprille JR (1993) Mechanism and regulation of the mitochondrial ATPMg/ P(i) carrier. J Bioenerg Biomembr 25:473-481. CrossRef Medline.
    • (1993) J Bioenerg Biomembr , vol.25 , pp. 473-481
    • Aprille, J.R.1
  • 11
    • 0020459256 scopus 로고
    • Adenine nucleotide content of liver mitochondria increases after glucagon treatment of rats or isolated hepatocytes
    • CrossRef Medline
    • Aprille JR, Nosek MT, Brennan WA Jr (1982) Adenine nucleotide content of liver mitochondria increases after glucagon treatment of rats or isolated hepatocytes. Biochem Biophys Res Commun 108:834-839. CrossRef Medline.
    • (1982) Biochem Biophys Res Commun , vol.108 , pp. 834-839
    • Aprille, J.R.1    Nosek, M.T.2    Brennan, W.A.3
  • 12
    • 0034784359 scopus 로고    scopus 로고
    • Anenergy budget for signaling in the grey matter of the brain
    • CrossRef Medline
    • Attwell D, Laughlin SB (2001) Anenergy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab 21:1133-1145. CrossRef Medline.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1133-1145
    • Attwell, D.1    Laughlin, S.B.2
  • 13
    • 0019398471 scopus 로고
    • Epilepsy: Changes in local glucose consumption and brain pathology produced by kainic acid
    • Medline
    • Ben-Ari Y (1981) Epilepsy: changes in local glucose consumption and brain pathology produced by kainic acid. Adv Biochem Psychopharmacol 27: 385-394. Medline.
    • (1981) Adv Biochem Psychopharmacol , vol.27 , pp. 385-394
    • Ben-Ari, Y.1
  • 15
    • 43449133572 scopus 로고    scopus 로고
    • Measurements of mitochondrial pH in cultured cortical neurons clarify contribution of mitochondrial pore to the mechanism of glutamate-induced delayed Ca2+ deregulation
    • CrossRef Medline
    • Bolshakov AP, Mikhailova MM, Szabadkai G, Pinelis VG, Brustovetsky N, Rizzuto R, Khodorov BI (2008) Measurements of mitochondrial pH in cultured cortical neurons clarify contribution of mitochondrial pore to the mechanism of glutamate-induced delayed Ca2+ deregulation. Cell Calcium 43:602-614. CrossRef Medline.
    • (2008) Cell Calcium , vol.43 , pp. 602-614
    • Bolshakov, A.P.1    Mikhailova, M.M.2    Szabadkai, G.3    Pinelis, V.G.4    Brustovetsky, N.5    Rizzuto, R.6    Khodorov, B.I.7
  • 18
    • 84879732033 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase couples NMDA receptors to superoxide release in excitotoxic neuronal death
    • CrossRef Medline
    • Brennan-Minnella AM, Shen Y, El-Benna J, Swanson RA (2013) Phosphoinositide 3-kinase couples NMDA receptors to superoxide release in excitotoxic neuronal death. Cell Death Dis 4:e580. CrossRef Medline.
    • (2013) Cell Death Dis , vol.4
    • Brennan-Minnella, A.M.1    Shen, Y.2    El-Benna, J.3    Swanson, R.A.4
  • 19
    • 0027226219 scopus 로고
    • Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serumfree medium combination
    • CrossRef Medline
    • Brewer GJ, Torricelli JR, Evege EK, Price PJ (1993) Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serumfree medium combination. J Neurosci Res 35:567-576. CrossRef Medline.
    • (1993) J Neurosci Res , vol.35 , pp. 567-576
    • Brewer, G.J.1    Torricelli, J.R.2    Evege, E.K.3    Price, P.J.4
  • 20
    • 0029827804 scopus 로고    scopus 로고
    • Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells
    • Medline
    • Budd SL, Nicholls DG (1996) Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurochem 67:2282-2291. Medline.
    • (1996) J Neurochem , vol.67 , pp. 2282-2291
    • Budd, S.L.1    Nicholls, D.G.2
  • 21
    • 0038143180 scopus 로고    scopus 로고
    • The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria
    • CrossRef Medline
    • Chalmers S, Nicholls DG (2003) The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria. J Biol Chem 278:19062-19070. CrossRef Medline.
    • (2003) J Biol Chem , vol.278 , pp. 19062-19070
    • Chalmers, S.1    Nicholls, D.G.2
  • 22
    • 0027946642 scopus 로고
    • Oxidative mechanisms involved in kainateinduced cytotoxicity in cortical neurons
    • CrossRef Medline
    • Cheng Y, Sun AY (1994) Oxidative mechanisms involved in kainateinduced cytotoxicity in cortical neurons. Neurochem Res 19:1557-1564. CrossRef Medline.
    • (1994) Neurochem Res , vol.19 , pp. 1557-1564
    • Cheng, Y.1    Sun, A.Y.2
  • 23
    • 65349105507 scopus 로고    scopus 로고
    • A novel kinetic assay of mitochondrial ATP-ADP exchange rate mediated by the ANT
    • CrossRef Medline
    • Chinopoulos C, Vajda S, Csanády L, Mándi M, Mathe K, Adam-Vizi V (2009) A novel kinetic assay of mitochondrial ATP-ADP exchange rate mediated by the ANT. Biophys J 96:2490-2504. CrossRef Medline.
    • (2009) Biophys J , vol.96 , pp. 2490-2504
    • Chinopoulos, C.1    Vajda, S.2    Csanády, L.3    Mándi, M.4    Mathe, K.5    Adam-Vizi, V.6
  • 25
    • 65449147539 scopus 로고    scopus 로고
    • Calcium signaling in brain mitochondria: Interplay of malate aspartateNADHshuttle and calcium uniporter/mitochondrial dehydrogenase pathways
    • CrossRef Medline
    • Contreras L, Satrú stegui J (2009) Calcium signaling in brain mitochondria: interplay of malate aspartateNADHshuttle and calcium uniporter/mitochondrial dehydrogenase pathways. J Biol Chem 284:7091-7099. CrossRef Medline.
    • (2009) J Biol Chem , vol.284 , pp. 7091-7099
    • Contreras, L.1    Satrú Stegui, J.2
  • 26
    • 40949116689 scopus 로고    scopus 로고
    • Assessing mitochondrial potential, calcium, and redox state in isolated mammalian cells using confocal microscopy
    • CrossRef Medline
    • Davidson SM, Yellon D, Duchen MR (2007) Assessing mitochondrial potential, calcium, and redox state in isolated mammalian cells using confocal microscopy. Methods Mol Biol 372:421-430. CrossRef Medline.
    • (2007) Methods Mol Biol , vol.372 , pp. 421-430
    • Davidson, S.M.1    Yellon, D.2    Duchen, M.R.3
  • 27
    • 84864369195 scopus 로고    scopus 로고
    • Mitochondrial free [Ca(2+)] dynamics measured with a novel low-Ca(2+) affinity aequorin probe
    • CrossRef Medline
    • de la Fuente S, Fonteriz RI, de la Cruz PJ, Montero M, Alvarez J (2012) Mitochondrial free [Ca(2+)] dynamics measured with a novel low-Ca(2+) affinity aequorin probe. Biochem J 445:371-376. CrossRef Medline.
    • (2012) Biochem J , vol.445 , pp. 371-376
    • De La Fuente, S.1    Fonteriz, R.I.2    De La Cruz, P.J.3    Montero, M.4    Alvarez, J.5
  • 28
    • 2642522210 scopus 로고    scopus 로고
    • Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains
    • CrossRef Medline
    • del Arco A, Satrú stegui J (2004) Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains. J Biol Chem 279:24701-24713. CrossRef Medline.
    • (2004) J Biol Chem , vol.279 , pp. 24701-24713
    • Del Arco, A.1    Satrú Stegui, J.2
  • 30
    • 37249047093 scopus 로고    scopus 로고
    • Ca2+-dependent generation of mitochondrial reactive oxygen species serves as a signal for poly(ADP-ribose) polymerase-1 activation during glutamate excitotoxicity
    • CrossRef Medline
    • Duan Y, Gross RA, Sheu SS (2007) Ca2+-dependent generation of mitochondrial reactive oxygen species serves as a signal for poly(ADP-ribose) polymerase-1 activation during glutamate excitotoxicity. J Physiol 585: 741-758. CrossRef Medline.
    • (2007) J Physiol , vol.585 , pp. 741-758
    • Duan, Y.1    Gross, R.A.2    Sheu, S.S.3
  • 31
    • 84863522994 scopus 로고    scopus 로고
    • Mitochondria, calcium-dependent neuronal death and neurodegenerative disease
    • CrossRef Medline
    • Duchen MR (2012) Mitochondria, calcium-dependent neuronal death and neurodegenerative disease. Pflugers Arch 464:111-121. CrossRef Medline.
    • (2012) Pflugers Arch , vol.464 , pp. 111-121
    • Duchen, M.R.1
  • 33
    • 3142764629 scopus 로고    scopus 로고
    • Identification of the mitochondrial ATP-Mg/Pi transporter: Bacterial expression, reconstitution, functional characterization and tissue distribution
    • CrossRef Medline
    • Fiermonte G, De Leonardis F, Todisco S, Palmieri L, Lasorsa FM, Palmieri F (2004) Identification of the mitochondrial ATP-Mg/Pi transporter: bacterial expression, reconstitution, functional characterization and tissue distribution. J Biol Chem 279:30722-30730. CrossRef Medline.
    • (2004) J Biol Chem , vol.279 , pp. 30722-30730
    • Fiermonte, G.1    De Leonardis, F.2    Todisco, S.3    Palmieri, L.4    Lasorsa, F.M.5    Palmieri, F.6
  • 37
    • 32544437394 scopus 로고    scopus 로고
    • Prolonged seizures and cellular injury: Understanding the connection
    • CrossRef Medline
    • Fujikawa DG (2005) Prolonged seizures and cellular injury: understanding the connection. Epilepsy Behav 7 [Suppl 3]:S3-S11. CrossRef Medline.
    • (2005) Epilepsy Behav , vol.7
    • Fujikawa, D.G.1
  • 40
    • 84859560882 scopus 로고    scopus 로고
    • Role of mitochondrial Ca2+in the regulation of cellular energetics
    • CrossRef Medline
    • Glancy B, Balaban RS (2012) Role of mitochondrial Ca2+in the regulation of cellular energetics. Biochemistry 51:2959-2973. CrossRef Medline.
    • (2012) Biochemistry , vol.51 , pp. 2959-2973
    • Glancy, B.1    Balaban, R.S.2
  • 41
    • 62649113414 scopus 로고    scopus 로고
    • Simultaneous single neuron recording of O2consumption, [Ca2+]iand mitochondrial membrane potential in glutamate toxicity
    • CrossRef Medline
    • Gleichmann M, Collis LP, Smith PJ, Mattson MP (2009) Simultaneous single neuron recording of O2consumption, [Ca2+]iand mitochondrial membrane potential in glutamate toxicity. J Neurochem 109:644-655. CrossRef Medline.
    • (2009) J Neurochem , vol.109 , pp. 644-655
    • Gleichmann, M.1    Collis, L.P.2    Smith, P.J.3    Mattson, M.P.4
  • 42
    • 84879165309 scopus 로고    scopus 로고
    • The developmental regulation of glutamate receptor-mediated calcium signaling in primary cultured rat hippocampal neurons
    • CrossRef Medline
    • Guo ZY, Li CZ, Li XJ, Wang YL, Mattson MP, Lu CB (2013) The developmental regulation of glutamate receptor-mediated calcium signaling in primary cultured rat hippocampal neurons. Neuroreport 24:492-497. CrossRef Medline.
    • (2013) Neuroreport , vol.24 , pp. 492-497
    • Guo, Z.Y.1    Li, C.Z.2    Li, X.J.3    Wang, Y.L.4    Mattson, M.P.5    Lu, C.B.6
  • 44
    • 77958171178 scopus 로고    scopus 로고
    • Mitochondrial free [Ca2+] increases during ATP/ADP antiport and ADP phosphorylation: Exploration of mechanisms
    • CrossRef Medline
    • Haumann J, Dash RK, Stowe DF, Boelens AD, Beard DA, Camara AK (2010) Mitochondrial free [Ca2+] increases during ATP/ADP antiport and ADP phosphorylation: exploration of mechanisms. Biophys J 99:997-1006. CrossRef Medline.
    • (2010) Biophys J , vol.99 , pp. 997-1006
    • Haumann, J.1    Dash, R.K.2    Stowe, D.F.3    Boelens, A.D.4    Beard, D.A.5    Camara, A.K.6
  • 45
    • 3543030406 scopus 로고    scopus 로고
    • In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate
    • CrossRef Medline
    • Jekabsons MB, Nicholls DG (2004) In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate. J Biol Chem 279:32989-33000. CrossRef Medline.
    • (2004) J Biol Chem , vol.279 , pp. 32989-33000
    • Jekabsons, M.B.1    Nicholls, D.G.2
  • 46
    • 84878961842 scopus 로고    scopus 로고
    • Letm1, the mitochondrial Ca2+/H_ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome
    • CrossRef Medline
    • Jiang D, Zhao L, Clish CB, Clapham DE (2013) Letm1, the mitochondrial Ca2+/H_ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome. Proc Natl Acad SciU S A 110:E2249-E2254. CrossRef Medline.
    • (2013) Proc Natl Acad Sciu S A , vol.110 , pp. E2249-E2254
    • Jiang, D.1    Zhao, L.2    Clish, C.B.3    Clapham, D.E.4
  • 47
    • 79952353862 scopus 로고    scopus 로고
    • Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture
    • CrossRef Medline
    • Kim SH, Lu HF, Alano CC (2011) Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture. PLoS One 6:e14731. CrossRef Medline.
    • (2011) Plos One , vol.6
    • Kim, S.H.1    Lu, H.F.2    Alano, C.C.3
  • 50
    • 33644781684 scopus 로고    scopus 로고
    • Isolation of mitochondria with high respiratory control from primary cultures of neurons and astrocytes using nitrogen cavitation
    • CrossRef Medline
    • Kristián T, Hopkins IB, McKenna MC, Fiskum G (2006) Isolation of mitochondria with high respiratory control from primary cultures of neurons and astrocytes using nitrogen cavitation. J Neurosci Methods 152:136-143. CrossRef Medline.
    • (2006) J Neurosci Methods , vol.152 , pp. 136-143
    • Kristián, T.1    Hopkins, I.B.2    McKenna, M.C.3    Fiskum, G.4
  • 52
    • 67649785237 scopus 로고    scopus 로고
    • Role of cyclophilin D-dependent mitochondrial permeability transition in glutamate-induced calcium deregulation and excitotoxic neuronal death
    • CrossRef Medline
    • Li V, Brustovetsky T, Brustovetsky N (2009) Role of cyclophilin D-dependent mitochondrial permeability transition in glutamate-induced calcium deregulation and excitotoxic neuronal death. Exp Neurol 218:171-182. CrossRef Medline.
    • (2009) Exp Neurol , vol.218 , pp. 171-182
    • Li, V.1    Brustovetsky, T.2    Brustovetsky, N.3
  • 53
    • 84882980197 scopus 로고    scopus 로고
    • Calcium-regulation of mitochondrial respiration maintains ATP homeostasis and requires ARALAR/AGC1-malate aspartate shuttle in intact cortical neurons
    • CrossRef Medline
    • Llorente-Folch I, Rueda CB, Amigo I, del Arco A, Saheki T, Pardo B, Satrú-stegui J (2013) Calcium-regulation of mitochondrial respiration maintains ATP homeostasis and requires ARALAR/AGC1-malate aspartate shuttle in intact cortical neurons. J Neurosci 33:13957-13971. CrossRef Medline.
    • (2013) J Neurosci , vol.33 , pp. 13957-13971
    • Llorente-Folch, I.1    Rueda, C.B.2    Amigo, I.3    Del Arco, A.4    Saheki, T.5    Pardo, B.6    Satrú-Stegui, J.7
  • 55
    • 0023492484 scopus 로고
    • Permeation and block of N-methyl-Daspartic acid receptor channels by divalent cations in mouse cultured central neurones
    • CrossRef Medline
    • Mayer ML, Westbrook GL (1987) Permeation and block of N-methyl-Daspartic acid receptor channels by divalent cations in mouse cultured central neurones. J Physiol 394:501-527. CrossRef Medline.
    • (1987) J Physiol , vol.394 , pp. 501-527
    • Mayer, M.L.1    Westbrook, G.L.2
  • 56
  • 57
    • 33750381007 scopus 로고    scopus 로고
    • Differential susceptibility to striatal neurodegeneration induced by quinolinic acid and kainate in inbred, outbred and hybrid mouse strains
    • CrossRef Medline
    • McLin JP, Thompson LM, Steward O (2006) Differential susceptibility to striatal neurodegeneration induced by quinolinic acid and kainate in inbred, outbred and hybrid mouse strains. Eur J Neurosci 24:3134-3140. CrossRef Medline.
    • (2006) Eur J Neurosci , vol.24 , pp. 3134-3140
    • McLin, J.P.1    Thompson, L.M.2    Steward, O.3
  • 58
    • 79960486405 scopus 로고    scopus 로고
    • Ca2+ regulation of mitochondrial ATP synthesis visualized at the single cell level
    • CrossRef Medline
    • Nakano M, Imamura H, Nagai T, Noji H (2011) Ca2+ regulation of mitochondrial ATP synthesis visualized at the single cell level. ACS Chem Biol 6:709-715. CrossRef Medline.
    • (2011) ACS Chem Biol , vol.6 , pp. 709-715
    • Nakano, M.1    Imamura, H.2    Nagai, T.3    Noji, H.4
  • 59
    • 57649178442 scopus 로고    scopus 로고
    • Oxidative stress and energy crises in neuronal dysfunction
    • CrossRef Medline
    • Nicholls DG (2008) Oxidative stress and energy crises in neuronal dysfunction. Ann N Y Acad Sci 1147:53-60. CrossRef Medline.
    • (2008) Ann N Y Acad Sci , vol.1147 , pp. 53-60
    • Nicholls, D.G.1
  • 60
    • 0028172376 scopus 로고
    • Comparison of the effects of Ca2+, adenine nucleotides and pH on the kinetic properties of mitochondrial (NAD+)-isocitrate dehydrogenase and oxoglutarate dehydrogenase from the yeast Saccharomyces cerevisiae and rat heart
    • Medline
    • Nichols BJ, Rigoulet M, Denton RM (1994) Comparison of the effects of Ca2+, adenine nucleotides and pH on the kinetic properties of mitochondrial (NAD+)-isocitrate dehydrogenase and oxoglutarate dehydrogenase from the yeast Saccharomyces cerevisiae and rat heart. Biochem J 303:461-465. Medline.
    • (1994) Biochem J , vol.303 , pp. 461-465
    • Nichols, B.J.1    Rigoulet, M.2    Denton, R.M.3
  • 61
    • 0025345597 scopus 로고
    • Calcium stimulates ATPMg/ Pi carrier activiry in rat liver mitochondria
    • Medline
    • Nosek MT, Dransfield DT, Aprille JR (1990) Calcium stimulates ATPMg/ Pi carrier activiry in rat liver mitochondria. J Biol Chem 265:8444-8450. Medline.
    • (1990) J Biol Chem , vol.265 , pp. 8444-8450
    • Nosek, M.T.1    Dransfield, D.T.2    Aprille, J.R.3
  • 62
    • 0014682523 scopus 로고
    • Brain lesions in an infant rhesus monkey treated with monsodium glutamate
    • CrossRef Medline
    • Olney JW, Sharpe LG (1969) Brain lesions in an infant rhesus monkey treated with monsodium glutamate. Science 166:386-388. CrossRef Medline.
    • (1969) Science , vol.166 , pp. 386-388
    • Olney, J.W.1    Sharpe, L.G.2
  • 63
    • 1542343927 scopus 로고    scopus 로고
    • Evidence for mitochondrial K+ channels and their role in cardioprotection
    • CrossRef Medline
    • O’Rourke B (2004) Evidence for mitochondrial K+ channels and their role in cardioprotection. Circ Res 94:420-432. CrossRef Medline.
    • (2004) Circ Res , vol.94 , pp. 420-432
    • O’rourke, B.1
  • 66
    • 77955266829 scopus 로고    scopus 로고
    • Alterations in bioenergetics due to changes in mitochondrial DNA copy number
    • CrossRef Medline
    • Qian W, Van Houten B (2010) Alterations in bioenergetics due to changes in mitochondrial DNA copy number. Methods 51:452-457. CrossRef Medline.
    • (2010) Methods , vol.51 , pp. 452-457
    • Qian, W.1    Van Houten, B.2
  • 67
    • 84879627185 scopus 로고    scopus 로고
    • Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals
    • CrossRef Medline
    • Qiu J, Tan YW, Hagenston AM, Martel MA, Kneisel N, Skehel PA, Wyllie DJ, Bading H, Hardingham GE (2013) Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals. Nat Commun 4:2034. CrossRef Medline.
    • (2013) Nat Commun , vol.4
    • Qiu, J.1    Tan, Y.W.2    Hagenston, A.M.3    Martel, M.A.4    Kneisel, N.5    Skehel, P.A.6    Wyllie, D.J.7    Bading, H.8    Hardingham, G.E.9
  • 68
    • 84894150737 scopus 로고    scopus 로고
    • Activity-driven local ATP synthesis is required for synaptic function
    • CrossRef Medline
    • Rangaraju V, Calloway N, Ryan TA (2014) Activity-driven local ATP synthesis is required for synaptic function. Cell 156:825-835. CrossRef Medline.
    • (2014) Cell , vol.156 , pp. 825-835
    • Rangaraju, V.1    Calloway, N.2    Ryan, T.A.3
  • 69
    • 44949142269 scopus 로고    scopus 로고
    • The selective detection of mitochondrial superoxide by live cell imaging
    • CrossRef Medline
    • Robinson KM, Janes MS, Beckman JS (2008) The selective detection of mitochondrial superoxide by live cell imaging. Nat Protoc 3:941-947. CrossRef Medline.
    • (2008) Nat Protoc , vol.3 , pp. 941-947
    • Robinson, K.M.1    Janes, M.S.2    Beckman, J.S.3
  • 70
    • 3242668920 scopus 로고    scopus 로고
    • Presynaptic kainate receptor facilitation of glutamate release involves protein kinase A in the rat hippocampus
    • CrossRef Medline
    • Rodríguez-Moreno A, Sihra TS (2004) Presynaptic kainate receptor facilitation of glutamate release involves protein kinase A in the rat hippocampus. J Physiol 557:733-745. CrossRef Medline.
    • (2004) J Physiol , vol.557 , pp. 733-745
    • Rodríguez-Moreno, A.1    Sihra, T.S.2
  • 71
    • 0032150860 scopus 로고    scopus 로고
    • Glutamate-induced neuron death requires mitochondrial calcium uptake
    • CrossRef Medline
    • Stout AK, Raphael HM, Kanterewicz BI, Klann E, Reynolds IJ (1998) Glutamate-induced neuron death requires mitochondrial calcium uptake. Nat Neurosci 1:366-373. CrossRef Medline.
    • (1998) Nat Neurosci , vol.1 , pp. 366-373
    • Stout, A.K.1    Raphael, H.M.2    Kanterewicz, B.I.3    Klann, E.4    Reynolds, I.J.5
  • 72
    • 84888873103 scopus 로고    scopus 로고
    • Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio
    • CrossRef Medline
    • Tantama M, Martínez-François JR, Mongeon R, Yellen G (2013) Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio. Nat Commun 4:2550. CrossRef Medline.
    • (2013) Nat Commun , vol.4 , pp. 2550
    • Tantama, M.1    Martínez-François, J.R.2    Mongeon, R.3    Yellen, G.4
  • 73
    • 1042289759 scopus 로고    scopus 로고
    • The Escherichia coli F1F0 ATP synthase displays biphasic synthesis kinetics
    • CrossRef Medline
    • Tomashek JJ, Glagoleva OB, Brusilow WS (2004) The Escherichia coli F1F0 ATP synthase displays biphasic synthesis kinetics. J Biol Chem 279:4465-4470. CrossRef Medline.
    • (2004) J Biol Chem , vol.279 , pp. 4465-4470
    • Tomashek, J.J.1    Glagoleva, O.B.2    Brusilow, W.S.3
  • 74
    • 84858158689 scopus 로고    scopus 로고
    • SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca2+ buffering
    • CrossRef Medline
    • Traba J, Del Arco A, Duchen MR, Szabadkai G, Satrú stegui J (2012) SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca2+ buffering. Cell Death Differ 19:650-660. CrossRef Medline.
    • (2012) Cell Death Differ , vol.19 , pp. 650-660
    • Traba, J.1    Del Arco, A.2    Duchen, M.R.3    Szabadkai, G.4    Satrú Stegui, J.5
  • 75
    • 0027339920 scopus 로고
    • Secondary Ca 2+ overload indicates early neuronal injury which precedes staining with viability indicators
    • CrossRef Medline
    • Tymianski M, Charlton MP, Carlen PL, Tator CH (1993) Secondary Ca 2+ overload indicates early neuronal injury which precedes staining with viability indicators. Brain Res 607:319-323. CrossRef Medline.
    • (1993) Brain Res , vol.607 , pp. 319-323
    • Tymianski, M.1    Charlton, M.P.2    Carlen, P.L.3    Tator, C.H.4
  • 76
    • 60349083027 scopus 로고    scopus 로고
    • Intracellular Zn2+ increases contribute to the progression of excitotoxic Ca2+ increases in apical dendrites of CA1 pyramidal neurons
    • CrossRef Medline
    • Vander Jagt TA, Connor JA, Weiss JH, Shuttleworth CW (2009) Intracellular Zn2+ increases contribute to the progression of excitotoxic Ca2+ increases in apical dendrites of CA1 pyramidal neurons. Neuroscience 159:104-114. CrossRef Medline.
    • (2009) Neuroscience , vol.159 , pp. 104-114
    • Vander Jagt, T.A.1    Connor, J.A.2    Weiss, J.H.3    Shuttleworth, C.W.4
  • 77
    • 58149474392 scopus 로고    scopus 로고
    • Kainate receptors in epilepsy and excitotoxicity
    • CrossRef Medline
    • Vincent P, Mulle C (2009) Kainate receptors in epilepsy and excitotoxicity. Neuroscience 158:309-323. CrossRef Medline.
    • (2009) Neuroscience , vol.158 , pp. 309-323
    • Vincent, P.1    Mulle, C.2
  • 79
    • 34447122557 scopus 로고    scopus 로고
    • Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone
    • CrossRef Medline
    • Yadava N, Nicholls DG (2007) Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone. J Neurosci 27:7310-7317. CrossRef Medline.
    • (2007) J Neurosci , vol.27 , pp. 7310-7317
    • Yadava, N.1    Nicholls, D.G.2
  • 82
    • 0028294246 scopus 로고
    • Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity
    • CrossRef Medline
    • Zhang J, Dawson VL, Dawson TM, Snyder SH (1994) Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 263:687-689. CrossRef Medline.
    • (1994) Science , vol.263 , pp. 687-689
    • Zhang, J.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.