메뉴 건너뛰기




Volumn 5, Issue , 2014, Pages

ERG induces taxane resistance in castration-resistant prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

CABAZITAXEL; DOCETAXEL; ERIBULIN; FLUTAMIDE; TUBULIN; VINCA ALKALOID; ANTINEOPLASTIC AGENT; ERG PROTEIN, HUMAN; TAXOID; TRANSACTIVATOR PROTEIN;

EID: 84923341662     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6548     Document Type: Article
Times cited : (103)

References (71)
  • 1
    • 77957682309 scopus 로고    scopus 로고
    • Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
    • De Bono, J. S. et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial. Lancet 376, 1147-1154 (2010).
    • (2010) Lancet , vol.376 , pp. 1147-1154
    • De Bono, J.S.1
  • 2
    • 4744337716 scopus 로고    scopus 로고
    • Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
    • Petrylak, D. P. et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. New Engl. J. Med. 351, 1513-1520 (2004).
    • (2004) New Engl. J. Med. , vol.351 , pp. 1513-1520
    • Petrylak, D.P.1
  • 3
    • 4744366279 scopus 로고    scopus 로고
    • Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
    • Tannock, I. F. et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. New Engl. J. Med. 351, 1502-1512 (2004).
    • (2004) New Engl. J. Med. , vol.351 , pp. 1502-1512
    • Tannock, I.F.1
  • 4
    • 0021686169 scopus 로고
    • Dynamic instability of microtubule growth
    • Mitchison, T. & Kirschner, M. Dynamic instability of microtubule growth. Nature 312, 237-242 (1984).
    • (1984) Nature , vol.312 , pp. 237-242
    • Mitchison, T.1    Kirschner, M.2
  • 6
    • 0035168410 scopus 로고    scopus 로고
    • Cell cycledependent changes in microtubule dynamics in living cells expressing green fluorescent protein-alpha tubulin
    • Rusan, N. M., Fagerstrom, C. J., Yvon, A. M. & Wadsworth, P. Cell cycledependent changes in microtubule dynamics in living cells expressing green fluorescent protein-alpha tubulin. Mol. Biol. Cell 12, 971-980 (2001).
    • (2001) Mol. Biol. Cell , vol.12 , pp. 971-980
    • Rusan, N.M.1    Fagerstrom, C.J.2    Yvon, A.M.3    Wadsworth, P.4
  • 7
    • 33845899396 scopus 로고    scopus 로고
    • Severe acute toxicity associated with high-dose methotrexate (MTX) therapy: Use of therapeutic drug monitoring and test-dose to guide carboxypeptidase G2 rescue and MTX continuation
    • Esteve, M. A. et al. Severe acute toxicity associated with high-dose methotrexate (MTX) therapy: Use of therapeutic drug monitoring and test-dose to guide carboxypeptidase G2 rescue and MTX continuation. Eur. J. Clin. Pharmacol. 63, 39-42 (2007).
    • (2007) Eur. J. Clin. Pharmacol. , vol.63 , pp. 39-42
    • Esteve, M.A.1
  • 8
    • 0032495513 scopus 로고    scopus 로고
    • Structure of the alpha beta tubulin dimer by electron crystallography
    • Nogales, E., Wolf, S. G. & Downing, K. H. Structure of the alpha beta tubulin dimer by electron crystallography. Nature 391, 199-203 (1998).
    • (1998) Nature , vol.391 , pp. 199-203
    • Nogales, E.1    Wolf, S.G.2    Downing, K.H.3
  • 9
    • 77649191871 scopus 로고    scopus 로고
    • Microtubules and resistance to tubulin-binding agents
    • Kavallaris, M. Microtubules and resistance to tubulin-binding agents. Nat. Rev. Cancer 10, 194-204 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 194-204
    • Kavallaris, M.1
  • 10
    • 79955968629 scopus 로고    scopus 로고
    • Mechanistic rationale for inhibition of Poly(ADP-Ribose) polymerase in ETS gene fusion-positive prostate cancer
    • Brenner, J. C. et al. Mechanistic rationale for inhibition of Poly(ADP-Ribose) polymerase in ETS gene fusion-positive prostate cancer. Cancer Cell 19, 664-678 (2011).
    • (2011) Cancer Cell , vol.19 , pp. 664-678
    • Brenner, J.C.1
  • 11
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins, S. A. et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310, 644-648 (2005).
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1
  • 12
    • 34447342868 scopus 로고    scopus 로고
    • TMPRSS2-ERG fusion prostate cancer: An early molecular event associated with invasion
    • Perner, S. et al. TMPRSS2-ERG fusion prostate cancer: An early molecular event associated with invasion. Am. J. Surg. Pathol. 31, 882-888 (2007).
    • (2007) Am. J. Surg. Pathol. , vol.31 , pp. 882-888
    • Perner, S.1
  • 13
    • 84883823918 scopus 로고    scopus 로고
    • The mutational landscape of prostate cancer
    • Barbieri, C. E. et al. The mutational landscape of prostate cancer. Eur. Urol. 64, 567-576 (2013).
    • (2013) Eur. Urol. , vol.64 , pp. 567-576
    • Barbieri, C.E.1
  • 14
    • 78649890593 scopus 로고    scopus 로고
    • ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression
    • Rickman, D. S. et al. ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression. Neoplasia 12, 1031-1040 (2010).
    • (2010) Neoplasia , vol.12 , pp. 1031-1040
    • Rickman, D.S.1
  • 15
    • 39049150843 scopus 로고    scopus 로고
    • Role of the TMPRSS2-ERG gene fusion in prostate cancer
    • Tomlins, S. A. et al. Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia 10, 177-188 (2008).
    • (2008) Neoplasia , vol.10 , pp. 177-188
    • Tomlins, S.A.1
  • 16
    • 84866754239 scopus 로고    scopus 로고
    • Oncogenic transcription factors as master regulators of chromatin topology: A new role for ERG in prostate cancer
    • Elemento, O., Rubin, M. A. & Rickman, D. S. Oncogenic transcription factors as master regulators of chromatin topology: A new role for ERG in prostate cancer. Cell Cycle 11, 3380-3383 (2012).
    • (2012) Cell Cycle , vol.11 , pp. 3380-3383
    • Elemento, O.1    Rubin, M.A.2    Rickman, D.S.3
  • 17
    • 84861860413 scopus 로고    scopus 로고
    • Oncogene-mediated alterations in chromatin conformation
    • Rickman, D. S. et al. Oncogene-mediated alterations in chromatin conformation. Proc. Natl Acad. Sci. USA 109, 9083-9088 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 9083-9088
    • Rickman, D.S.1
  • 18
    • 84860168795 scopus 로고    scopus 로고
    • Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets
    • Beltran, H. et al. Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets. Cancer Discov. 1, 487-495 (2011).
    • (2011) Cancer Discov. , vol.1 , pp. 487-495
    • Beltran, H.1
  • 19
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan, M. A. & Wilson, L. Microtubules as a target for anticancer drugs. Nat. Rev. Cancer 4, 253-265 (2004).
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 20
    • 0030758777 scopus 로고    scopus 로고
    • Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization
    • Giannakakou, P. et al. Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization. J. Biol. Chem. 272, 17118-17125 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 17118-17125
    • Giannakakou, P.1
  • 21
    • 48849095626 scopus 로고    scopus 로고
    • EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1
    • Thomas, S. L. et al. EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1. Cell Cycle 7, 2409-2417 (2008).
    • (2008) Cell Cycle , vol.7 , pp. 2409-2417
    • Thomas, S.L.1
  • 22
    • 12944277104 scopus 로고    scopus 로고
    • A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells
    • Giannakakou, P. et al. A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells. Proc. Natl. Acad. Sci. USA 97, 2904-2909 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 2904-2909
    • Giannakakou, P.1
  • 23
    • 81855196008 scopus 로고    scopus 로고
    • Post-translational regulation of the microtubule cytoskeleton: Mechanisms and functions
    • Janke, C. & Bulinski, J. C. Post-translational regulation of the microtubule cytoskeleton: Mechanisms and functions. Nat. Rev. Mol. Cell Biol. 12, 773-786 (2011).
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 773-786
    • Janke, C.1    Bulinski, J.C.2
  • 24
    • 34548830425 scopus 로고    scopus 로고
    • The tubulin code
    • Verhey, K. J. & Gaertig, J. The tubulin code. Cell Cycle 6, 2152-2160 (2007).
    • (2007) Cell Cycle , vol.6 , pp. 2152-2160
    • Verhey, K.J.1    Gaertig, J.2
  • 25
    • 84897767196 scopus 로고    scopus 로고
    • Acetylated tubulin (AT) as a prognostic marker in squamous cell carcinoma of the head and neck
    • Saba, N. F. et al. Acetylated tubulin (AT) as a prognostic marker in squamous cell carcinoma of the head and neck. Head Neck Pathol. 8, 66-72 (2014).
    • (2014) Head Neck Pathol. , vol.8 , pp. 66-72
    • Saba, N.F.1
  • 26
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman, M. M. & Pastan, I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem. 62, 385-427 (1993).
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 27
    • 0021259334 scopus 로고
    • Reversal of adriamycin resistance by verapamil in human ovarian cancer
    • Rogan, A. M., Hamilton, T. C., Young, R. C., Klecker, Jr R. W. & Ozols, R. F. Reversal of adriamycin resistance by verapamil in human ovarian cancer. Science 224, 994-996 (1984).
    • (1984) Science , vol.224 , pp. 994-996
    • Rogan, A.M.1    Hamilton, T.C.2    Young, R.C.3    Klecker, R.W.4    Ozols, R.F.5
  • 28
    • 0008632564 scopus 로고
    • Expression of a fulllength cDNA for the human ?MDR1' gene confers resistance to colchicine, doxorubicin, and vinblastine
    • Ueda, K., Cardarelli, C., Gottesman, M. M. & Pastan, I. Expression of a fulllength cDNA for the human ?MDR1' gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc. Natl Acad. Sci. USA 84, 3004-3008 (1987).
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 3004-3008
    • Ueda, K.1    Cardarelli, C.2    Gottesman, M.M.3    Pastan, I.4
  • 29
    • 37249075604 scopus 로고    scopus 로고
    • Reconstitution of a microtubule plus-end tracking system in vitro
    • Bieling, P. et al. Reconstitution of a microtubule plus-end tracking system in vitro. Nature 450, 1100-1105 (2007).
    • (2007) Nature , vol.450 , pp. 1100-1105
    • Bieling, P.1
  • 30
    • 34748862943 scopus 로고    scopus 로고
    • Structural basis of microtubule plus end tracking by XMAP215 CLIP-170 and EB1
    • Slep, K. C. & Vale, R. D. Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1. Mol. Cell 27, 976-991 (2007).
    • (2007) Mol. Cell , vol.27 , pp. 976-991
    • Slep, K.C.1    Vale, R.D.2
  • 31
    • 77956340867 scopus 로고    scopus 로고
    • Analysis of microtubule dynamic instability using a plus-end growth marker
    • Matov, A. et al. Analysis of microtubule dynamic instability using a plus-end growth marker. Nat. Methods 7, 761-768 (2010).
    • (2010) Nat. Methods , vol.7 , pp. 761-768
    • Matov, A.1
  • 32
    • 77954997528 scopus 로고    scopus 로고
    • Antibody-based detection of ERG rearrangement-positive prostate cancer
    • Park, K. et al. Antibody-based detection of ERG rearrangement-positive prostate cancer. Neoplasia 12, 590-598 (2010).
    • (2010) Neoplasia , vol.12 , pp. 590-598
    • Park, K.1
  • 33
    • 0032565916 scopus 로고    scopus 로고
    • Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains
    • Carrere, S., Verger, A., Flourens, A., Stehelin, D. & Duterque-Coquillaud, M. Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains. Oncogene 16, 3261-3268 (1998).
    • (1998) Oncogene , vol.16 , pp. 3261-3268
    • Carrere, S.1    Verger, A.2    Flourens, A.3    Stehelin, D.4    Duterque-Coquillaud, M.5
  • 34
    • 0035515347 scopus 로고    scopus 로고
    • The ETS-domain transcription factor family
    • Sharrocks, A. D. The ETS-domain transcription factor family. Nat. Rev. Mol. Cell Biol. 2, 827-837 (2001).
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 827-837
    • Sharrocks, A.D.1
  • 35
    • 0030048731 scopus 로고    scopus 로고
    • Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules
    • Belmont, L. D. & Mitchison, T. J. Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules. Cell 84, 623-631 (1996).
    • (1996) Cell , vol.84 , pp. 623-631
    • Belmont, L.D.1    Mitchison, T.J.2
  • 36
    • 80052808323 scopus 로고    scopus 로고
    • Taxane-induced blockade to nuclear accumulation of the androgen receptor predicts clinical responses in metastatic prostate cancer
    • Darshan, M. S. et al. Taxane-induced blockade to nuclear accumulation of the androgen receptor predicts clinical responses in metastatic prostate cancer. Cancer Res. 71, 6019-6029 (2011).
    • (2011) Cancer Res. , vol.71 , pp. 6019-6029
    • Darshan, M.S.1
  • 37
    • 0036678880 scopus 로고    scopus 로고
    • Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics
    • Giannakakou, P. et al. Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics. Proc. Natl Acad. Sci. USA 99, 10855-10860 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 10855-10860
    • Giannakakou, P.1
  • 38
    • 77955299726 scopus 로고    scopus 로고
    • Fluorescent taxoid probes for microtubule research
    • Barasoain, I., Diaz, J. F. & Andreu, J. M. Fluorescent taxoid probes for microtubule research. Methods Cell Biol. 95, 353-372 (2010).
    • (2010) Methods Cell Biol. , vol.95 , pp. 353-372
    • Barasoain, I.1    Diaz, J.F.2    Andreu, J.M.3
  • 39
    • 0037424365 scopus 로고    scopus 로고
    • Fast kinetics of Taxol binding to microtubules. Effects of solution variables and microtubule-associated proteins
    • Diaz, J. F., Barasoain, I. & Andreu, J. M. Fast kinetics of Taxol binding to microtubules. Effects of solution variables and microtubule-associated proteins. J. Biol. Chem. 278, 8407-8419 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 8407-8419
    • Diaz, J.F.1    Barasoain, I.2    Andreu, J.M.3
  • 40
    • 68049131467 scopus 로고    scopus 로고
    • Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer
    • Cai, C., Wang, H., Xu, Y., Chen, S. & Balk, S. P. Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer. Cancer Res. 69, 6027-6032 (2009).
    • (2009) Cancer Res. , vol.69 , pp. 6027-6032
    • Cai, C.1    Wang, H.2    Xu, Y.3    Chen, S.4    Balk, S.P.5
  • 41
    • 66149098947 scopus 로고    scopus 로고
    • Characterization of ERG AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer
    • Attard, G. et al. Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer. Cancer Res. 69, 2912-2918 (2009).
    • (2009) Cancer Res. , vol.69 , pp. 2912-2918
    • Attard, G.1
  • 42
    • 84923342654 scopus 로고    scopus 로고
    • Concordance of ETS fusion status of matched metastatic castration-resistant prostate cancer and primary prostate cancer: Data from NCI 9012, a randomized ETS fusion-stratified phase II trial
    • Kunju, L. K. et al. Concordance of ETS fusion status of matched metastatic castration-resistant prostate cancer and primary prostate cancer: Data from NCI 9012, a randomized ETS fusion-stratified phase II trial. J. Clin. Oncol. 32 (2014).
    • (2014) J. Clin. Oncol. , vol.32
    • Kunju, L.K.1
  • 43
    • 84860455199 scopus 로고    scopus 로고
    • Functional characterization of circulating tumor cells with a prostate-cancer-specific microfluidic device
    • Kirby, B. J. et al. Functional characterization of circulating tumor cells with a prostate-cancer-specific microfluidic device. PLoS ONE 7, e35976 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e35976
    • Kirby, B.J.1
  • 44
    • 84870050058 scopus 로고    scopus 로고
    • Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer
    • Miyamoto, D. T. et al. Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer. Cancer Discov. 2, 995-1003 (2012).
    • (2012) Cancer Discov. , vol.2 , pp. 995-1003
    • Miyamoto, D.T.1
  • 45
    • 66749188650 scopus 로고    scopus 로고
    • Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
    • Carver, B. S. et al. Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nat. Genet. 41, 619-624 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 619-624
    • Carver, B.S.1
  • 46
    • 80054755085 scopus 로고    scopus 로고
    • Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells
    • Hollenhorst, P. C. et al. Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells. Genes Dev. 25, 2147-2157 (2011).
    • (2011) Genes Dev. , vol.25 , pp. 2147-2157
    • Hollenhorst, P.C.1
  • 47
    • 54249154706 scopus 로고    scopus 로고
    • Pleiotropic biological activities of alternatively spliced TMPRSS2/ ERG fusion gene transcripts
    • Wang, J. et al. Pleiotropic biological activities of alternatively spliced TMPRSS2/ ERG fusion gene transcripts. Cancer. Res. 68, 8516-8524 (2008).
    • (2008) Cancer. Res. , vol.68 , pp. 8516-8524
    • Wang, J.1
  • 48
    • 84882285291 scopus 로고    scopus 로고
    • ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss
    • Chen, Y. et al. ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss. Nat. Med. 19, 1023-1029 (2013).
    • (2013) Nat. Med. , vol.19 , pp. 1023-1029
    • Chen, Y.1
  • 49
    • 66749100105 scopus 로고    scopus 로고
    • Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
    • King, J. C. et al. Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis. Nat. Genet. 41, 524-526 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 524-526
    • King, J.C.1
  • 50
    • 68149159298 scopus 로고    scopus 로고
    • ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells
    • Zong, Y. et al. ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells. Proc. Natl Acad. Sci. USA 106, 12465-12470 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 12465-12470
    • Zong, Y.1
  • 51
    • 77952103123 scopus 로고    scopus 로고
    • An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression
    • Yu, J. et al. An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer Cell 17, 443-454 (2010).
    • (2010) Cancer Cell , vol.17 , pp. 443-454
    • Yu, J.1
  • 52
    • 84875757638 scopus 로고    scopus 로고
    • Punctuated evolution of prostate cancer genomes
    • Baca, S. C. et al. Punctuated evolution of prostate cancer genomes. Cell 153, 666-677 (2013).
    • (2013) Cell , vol.153 , pp. 666-677
    • Baca, S.C.1
  • 53
    • 79951497419 scopus 로고    scopus 로고
    • The genomic complexity of primary human prostate cancer
    • Berger, M. F. et al. The genomic complexity of primary human prostate cancer. Nature 470, 214-220 (2011).
    • (2011) Nature , vol.470 , pp. 214-220
    • Berger, M.F.1
  • 54
    • 84906345112 scopus 로고    scopus 로고
    • Impact on overall survival (OS) with chemohormonal therapy versus hormonal therapy for hormone-sensitive newly metastatic prostate cancer (mPrCa): An ECOG-led phase III randomized trial
    • Sweeney, C. et al. Impact on overall survival (OS) with chemohormonal therapy versus hormonal therapy for hormone-sensitive newly metastatic prostate cancer (mPrCa): An ECOG-led phase III randomized trial. J. Clin. Oncol. 32 (2014).
    • (2014) J. Clin. Oncol. , vol.32
    • Sweeney, C.1
  • 56
    • 80054698475 scopus 로고    scopus 로고
    • Stathmin: A protein with many tasks New biomarker and potential target in cancer
    • Belletti, B. & Baldassarre, G. Stathmin: A protein with many tasks. New biomarker and potential target in cancer. Expert Opin. Ther. Targets 15, 1249-1266 (2011).
    • (2011) Expert Opin. Ther. Targets , vol.15 , pp. 1249-1266
    • Belletti, B.1    Baldassarre, G.2
  • 57
    • 46749154962 scopus 로고    scopus 로고
    • Stathmin/Op18 is a novel mediator of vinblastine activity
    • Devred, F. et al. Stathmin/Op18 is a novel mediator of vinblastine activity. FEBS Lett. 582, 2484-2488 (2008).
    • (2008) FEBS Lett. , vol.582 , pp. 2484-2488
    • Devred, F.1
  • 58
    • 84900851474 scopus 로고    scopus 로고
    • Enriched variations in TEKT4 and breast cancer resistance to paclitaxel
    • Jiang, Y. Z. et al. Enriched variations in TEKT4 and breast cancer resistance to paclitaxel. Nat. Commun. 5, 3802 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 3802
    • Jiang, Y.Z.1
  • 59
    • 0027518831 scopus 로고
    • The Drosophila gene pointed encodes two ETS-like proteins which are involved in the development of the midline glial cells
    • Klambt, C. The Drosophila gene pointed encodes two ETS-like proteins which are involved in the development of the midline glial cells. Development 117, 163-176 (1993).
    • (1993) Development , vol.117 , pp. 163-176
    • Klambt, C.1
  • 60
    • 15444339209 scopus 로고    scopus 로고
    • A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia
    • Lacronique, V. et al. A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. Science 278, 1309-1312 (1997).
    • (1997) Science , vol.278 , pp. 1309-1312
    • Lacronique, V.1
  • 61
    • 0035902045 scopus 로고    scopus 로고
    • Mae mediates MAP kinase phosphorylation of Ets transcription factors in Drosophila
    • Baker, D. A., Mille-Baker, B.,Wainwright, S. M., Ish-Horowicz, D. & Dibb, N. J. Mae mediates MAP kinase phosphorylation of Ets transcription factors in Drosophila. Nature 411, 330-334 (2001).
    • (2001) Nature , vol.411 , pp. 330-334
    • Baker, D.A.1    Mille-Baker, B.2    Wainwright, S.M.3    Ish-Horowicz, D.4    Dibb, N.J.5
  • 62
    • 78049294167 scopus 로고    scopus 로고
    • Tubulin-targeting chemotherapy impairs androgen receptor activity in prostate cancer
    • Zhu, M. L. et al. Tubulin-targeting chemotherapy impairs androgen receptor activity in prostate cancer. Cancer Res. 70, 7992-8002 (2010).
    • (2010) Cancer Res. , vol.70 , pp. 7992-8002
    • Zhu, M.L.1
  • 63
    • 80053299958 scopus 로고    scopus 로고
    • TMPRSS2-ERG status in circulating tumor cells as a predictive biomarker of sensitivity in castration-resistant prostate cancer patients treated with abiraterone acetate
    • Danila, D. C. et al. TMPRSS2-ERG status in circulating tumor cells as a predictive biomarker of sensitivity in castration-resistant prostate cancer patients treated with abiraterone acetate. Eur. Urol. 60, 897-904 (2011).
    • (2011) Eur. Urol. , vol.60 , pp. 897-904
    • Danila, D.C.1
  • 64
    • 34249056542 scopus 로고    scopus 로고
    • Transposon-based interferon gamma gene transfer overcomes limitations of episomal plasmid for immunogene therapy of glioblastoma
    • Wu, A. et al. Transposon-based interferon gamma gene transfer overcomes limitations of episomal plasmid for immunogene therapy of glioblastoma. Cancer Gene. Ther. 14, 550-560 (2007).
    • (2007) Cancer Gene. Ther. , vol.14 , pp. 550-560
    • Wu, A.1
  • 65
    • 33749029695 scopus 로고    scopus 로고
    • TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer
    • Perner, S. et al. TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer. Cancer Res. 66, 8337-8341 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 8337-8341
    • Perner, S.1
  • 66
    • 47649133156 scopus 로고    scopus 로고
    • Clusterin knockdown using the antisense oligonucleotide OGX-011 re-sensitizes docetaxel-refractory prostate cancer PC-3 cells to chemotherapy
    • Sowery, R. D. et al. Clusterin knockdown using the antisense oligonucleotide OGX-011 re-sensitizes docetaxel-refractory prostate cancer PC-3 cells to chemotherapy. BJU. Int. 102, 389-397 (2008).
    • (2008) BJU. Int. , vol.102 , pp. 389-397
    • Sowery, R.D.1
  • 67
    • 0034581163 scopus 로고    scopus 로고
    • Tet repressor-based system for regulated gene expression in eukaryotic cells: Principles and advances
    • Baron, U. & Bujard, H. Tet repressor-based system for regulated gene expression in eukaryotic cells: Principles and advances. Methods Enzymol. 327, 401-421 (2000).
    • (2000) Methods Enzymol. , vol.327 , pp. 401-421
    • Baron, U.1    Bujard, H.2
  • 68
    • 84860726516 scopus 로고    scopus 로고
    • EB1-recruited microtubule +tIP complexes coordinate protrusion dynamics during 3D epithelial remodeling
    • Gierke, S. & Wittmann, T. EB1-recruited microtubule +TIP complexes coordinate protrusion dynamics during 3D epithelial remodeling. Curr. Biol. 22, 753-762 (2012).
    • (2012) Curr. Biol. , vol.22 , pp. 753-762
    • Gierke, S.1    Wittmann, T.2
  • 69
    • 77957198722 scopus 로고    scopus 로고
    • Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability
    • Thoma, C. R. et al. Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability. J. Cell Biol. 190, 991-1003 (2010).
    • (2010) J. Cell Biol. , vol.190 , pp. 991-1003
    • Thoma, C.R.1
  • 70
    • 41949104346 scopus 로고    scopus 로고
    • Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group
    • Scher, H. I. et al. Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group. J. Clin. Oncol. 26, 1148-1159 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , pp. 1148-1159
    • Scher, H.I.1
  • 71
    • 77951922478 scopus 로고    scopus 로고
    • Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody
    • Gleghorn, J. P. et al. Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody. Lab. Chip. 10, 27-29 (2010).
    • (2010) Lab. Chip. , vol.10 , pp. 27-29
    • Gleghorn, J.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.