Dynamic principle for designing antagonistic/agonistic molecules for EphA4 receptor, the only known ALS modifier

ACS Chemical Biology

Volumn 10, Issue 2, 2015, Pages 372-378

  Qin, Haina ^a   Lim, Liang Zhong ^a   Song, Jianxing ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

4 (2,5 DIMETHYL PYRROL 1 YL) 2 HYDROXYBENZOIC ACID; 5 (2,5 DIMETHYL PYRROL 1 YL) 2 HYDROXYBENZOIC ACID; DOXAZOSIN; EPHRIN RECEPTOR; EPHRIN RECEPTOR A4; EPHRIN RECEPTOR A4 ANTAGONIST; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; DIMERIZATION; DRUG DESIGN; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG TARGETING; LIGAND BINDING; MALIGNANT NEOPLASTIC DISEASE; MOLECULAR DYNAMICS; NERVE CELL PLASTICITY; NERVE FIBER REGENERATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; AGONISTS; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; HUMAN; METABOLISM; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

AMYOTROPHIC LATERAL SCLEROSIS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPHA4;

EID: 84923332736     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb500413n     Document Type: Article

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