Neuroinflammation and Aβ accumulation linked to systemic inflammation are decreased by genetic PKR down-regulation

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Carret Rebillat, Anne Sophie ^a   Pace, Clarisse ^a   Gourmaud, Sarah ^a   Ravasi, Laura ^b   Montagne Stora, Samantha ^a   Longueville, Sophie ^c   Tible, Marion ^a   Sudol, Erika ^a   Chang, Raymond Chuen Chung ^d   Paquet, Claire ^a,e   Mouton Liger, François ^a   Hugon, Jacques ^a,e  

^a HÔPITAL LARIBOISIÈRE   (France)

^b UNIV LILLE   (France)

^c INSTITUT DU FER À MOULIN   (France)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; ASPARTIC PROTEINASE; BACE1 PROTEIN, MOUSE; CYTOKINE; LIPOPOLYSACCHARIDE; PROTEIN KINASE R; SECRETASE; STAT3 PROTEIN;

ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BRAIN; DISEASE MODEL; DOWN REGULATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; HIPPOCAMPUS; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; METABOLISM; MICROGLIA; MOUSE; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PHOSPHORYLATION; POSITRON EMISSION TOMOGRAPHY;

AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; CYTOKINES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EIF-2 KINASE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HIPPOCAMPUS; INFLAMMATION; LIPOPOLYSACCHARIDES; MAGNETIC RESONANCE IMAGING; MICE; MICE, KNOCKOUT; MICROGLIA; PHOSPHORYLATION; POSITRON-EMISSION TOMOGRAPHY; STAT3 TRANSCRIPTION FACTOR;

EID: 84923327709     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep08489     Document Type: Article

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