Mitochondrial defects trigger proliferation of neighbouring cells via a senescence-associated secretory phenotype in Drosophila

Nature Communications

Volumn 5, Issue , 2014, Pages

  Nakamura, Mai ^a,b   Ohsawa, Shizue ^a   Igaki, Tatsushi ^a,c  

^a KYOTO UNIVERSITY   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; BIOLOGICAL MARKER; DROSOPHILA PROTEIN; GREEN FLUORESCENT PROTEIN; PROTEIN P53; RAS PROTEIN;

DEFECT; DNA; ENZYME ACTIVITY; GERM CELL; MITOCHONDRION; REACTION KINETICS; SENESCENCE; TUMOR;

ARTICLE; CELL CYCLE ARREST; CELL INTERACTION; CELL PROLIFERATION; DNA DAMAGE; DROSOPHILA; ENZYME ACTIVITY; MITOCHONDRION; NONHUMAN; PHENOTYPE; SENESCENCE; SIGNAL TRANSDUCTION; TUMOR GROWTH; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; CELL AGING; CYTOLOGY; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; EYE; G1 PHASE CELL CYCLE CHECKPOINT; HYPERTROPHY; METABOLISM; SECRETION (PROCESS);

ANIMALS; BIOLOGICAL MARKERS; CELL AGING; CELL PROLIFERATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENZYME ACTIVATION; EYE; G1 PHASE CELL CYCLE CHECKPOINTS; GREEN FLUORESCENT PROTEINS; HYPERTROPHY; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIA; MODELS, BIOLOGICAL; PHENOTYPE; RAS PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84923310248     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6264     Document Type: Article

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