Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Li, Xiaolin ^a,b   Fang, Evandro Fei ^c,d   Scheibye Knudsen, Morten ^c   Cui, Honghua ^e   Qiu, Lu ^b   Li, Jian ^b   He, Yuping ^b   Huang, Jing ^c   Bohr, Vilhelm A ^c   Ng, Tzi Bun ^d   Guo, Hongwei ^a  

^a FUDAN UNIVERSITY   (China)

^b Shanghai Entry Exit Inspection and Quarantine Bureau   (China)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d Prince of Wales Hospital   (Hong Kong)

^e Shanghai Stomatological Disease Centre   (China)

Author keywords

[No Author keywords available]

Indexed keywords

SIRT1 PROTEIN, RAT; SIRTUIN 1;

ANIMAL; BIOSYNTHESIS; DNA REPLICATION; DRUG EFFECTS; GENETICS; HUMAN; MALE; MITOCHONDRION; PATHOLOGY; RAT; REPRODUCTION; SPERMATOGENESIS; TESTIS;

ANIMALS; DNA REPLICATION; HUMANS; MALE; MITOCHONDRIA; RATS; REPRODUCTION; SIRTUIN 1; SPERMATOGENESIS; TESTIS;

EID: 84923304409     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep06434     Document Type: Article

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