A dose response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): Reproductive effects on adult male offspring rats

Toxicology

Volumn 228, Issue 1, 2006, Pages 85-97

  Andrade, Anderson J M ^a   Grande, Simone W ^a   Talsness, Chris E ^a   Gericke, Christine ^a   Grote, Konstanze ^a   Golombiewski, Andrea ^b   Sterner Kock, Anja ^b   Chahoud, Ibrahim ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Development; Di (2 ethylhexyl) phthalate (DEHP); Dose response; Endocrine disruptors; Male offspring rats; Reproductive effects

Indexed keywords

ARACHIS OIL; ENDOCRINE DISRUPTOR; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL TYPE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYPTORCHISM; DOSE RESPONSE; EPIDIDYMIS; FEMALE; GENITAL SYSTEM; GENITAL SYSTEM DISEASE; GESTATION PERIOD; LACTATION; MALE; MALE FERTILITY; MALE GENITAL SYSTEM; NONHUMAN; ORGAN WEIGHT; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROGENY; PROSTATE; QUANTITATIVE ANALYSIS; RAT; RAT STRAIN; REPRODUCTIVE TOXICITY; SEMINAL VESICLE; SERTOLI CELL; SEXUAL BEHAVIOR; SPERMATOCYTE; SPERMATOGENESIS; TESTIS; TESTIS FUNCTION; TESTOSTERONE BLOOD LEVEL;

ADMINISTRATION, ORAL; ANIMALS; DIETHYLHEXYL PHTHALATE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FERTILITY; GENITALIA, MALE; LACTATION; MALE; MATERNAL EXPOSURE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; PLASTICIZERS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; REPRODUCTION; SEXUAL BEHAVIOR, ANIMAL; SEXUAL MATURATION; SPERM COUNT; SPERMATOZOA; TESTIS; TESTOSTERONE;

ANIMALIA; ARACHIS HYPOGAEA; RATTUS NORVEGICUS;

EID: 33749659139     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.08.020     Document Type: Article

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