메뉴 건너뛰기




Volumn 5, Issue 1, 2012, Pages 109-121

Momordica Charantia lectin, a type II ribosome inactivating protein, exhibits antitumor activity toward human nasopharyngeal carcinoma cells in Vitro and in Vivo

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CASPASE 3; CASPASE 8; CASPASE 9; CYCLIN D1; CYTOCHROME C; LECTIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; MOMORDICA CHARANTIA EXTRACT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; RETINOBLASTOMA BINDING PROTEIN; RIBOSOME INACTIVATING PROTEIN;

EID: 84862907973     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-11-0203     Document Type: Article
Times cited : (93)

References (56)
  • 1
    • 20444472028 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma
    • DOI 10.1016/S0140-6736(05)66698-6, PII S0140673605666986
    • Wei WI, Sham JS. Nasopharyngeal carcinoma. Lancet 2005;365:2041-54. (Pubitemid 40812341)
    • (2005) Lancet , vol.365 , Issue.9476 , pp. 2041-2054
    • Wei, W.I.1    Sham, J.S.T.2
  • 3
    • 77954143076 scopus 로고    scopus 로고
    • A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci
    • Bei JX, Li Y, Jia WH, Feng BJ, Zhou G, Chen LZ, et al. A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. Nat Genet 2010;42:599-603.
    • (2010) Nat Genet , vol.42 , pp. 599-603
    • Bei, J.X.1    Li, Y.2    Jia, W.H.3    Feng, B.J.4    Zhou, G.5    Chen, L.Z.6
  • 4
    • 0002358470 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma: Classification and histological appearance
    • Nicholls JM. Nasopharyngeal carcinoma: classification and histological appearance. Adv Anat Path 1997;4:71-84.
    • (1997) Adv Anat Path , vol.4 , pp. 71-84
    • Nicholls, J.M.1
  • 6
    • 0036435155 scopus 로고    scopus 로고
    • Epidemiology of nasopharyngeal carcinoma
    • DOI 10.1016/S1044579X02000858
    • Yu MC, Yuan JM. Epidemiology of nasopharyngeal carcinoma. Semin Cancer Biol 2002;12:421-9. (Pubitemid 35370755)
    • (2002) Seminars in Cancer Biology , vol.12 , Issue.6 , pp. 421-429
    • Yu, M.C.1    Yuan, J.-M.2
  • 7
    • 53449100203 scopus 로고    scopus 로고
    • ApoG2, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces apoptosis and suppresses tumor growth in nasopharyngeal carcinoma xenografts
    • Hu ZY, Zhu XF, Zhong ZD, Sun J, Wang J, Yang D, et al. ApoG2, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces apoptosis and suppresses tumor growth in nasopharyngeal carcinoma xenografts. Int J Cancer 2008;123:2418-29.
    • (2008) Int J Cancer , vol.123 , pp. 2418-2429
    • Hu, Z.Y.1    Zhu, X.F.2    Zhong, Z.D.3    Sun, J.4    Wang, J.5    Yang, D.6
  • 8
    • 79959293885 scopus 로고    scopus 로고
    • Bitter gourd (Momordica charantia) is a cornucopia of health: A review of its credited antidiabetic, anti-HIV, and antitumor properties
    • Fang EF, Ng TB. Bitter gourd (Momordica charantia) is a cornucopia of health: A review of its credited antidiabetic, anti-HIV, and antitumor properties. Curr Mol Med 2011;11:417-36.
    • (2011) Curr Mol Med , vol.11 , pp. 417-436
    • Fang, E.F.1    Ng, T.B.2
  • 9
    • 0021025259 scopus 로고
    • In vivo antitumor activity of the bitter melon (Momordica charantia)
    • Jilka C, Strifler B, Fortner GW, Hays EF, Takemoto DJ. In vivo antitumor activity of the bitter melon (Momordica charantia). Cancer Res 1983;43:5151-5. (Pubitemid 14227492)
    • (1983) Cancer Research , vol.43 , Issue.11 , pp. 5151-5155
    • Jilka, C.1    Strifler, B.2    Fortner, G.W.3
  • 10
    • 77950278220 scopus 로고    scopus 로고
    • Bitter melon (Momordica charantia) extract inhibits breast cancer cell proliferation by modulating cell cycle regulatory genes and promotes apoptosis
    • Ray RB, Raychoudhuri A, Steele R, Nerurkar P. Bitter melon (Momordica charantia) extract inhibits breast cancer cell proliferation by modulating cell cycle regulatory genes and promotes apoptosis. Cancer Res 2010;70:1925-31.
    • (2010) Cancer Res , vol.70 , pp. 1925-1931
    • Ray, R.B.1    Raychoudhuri, A.2    Steele, R.3    Nerurkar, P.4
  • 11
    • 67650097017 scopus 로고    scopus 로고
    • Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells
    • Xiong SD, Yu K, Liu XH, Yin LH, Kirschenbaum A, Yao S, et al. Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells. Int J Cancer 2009;125:774-82.
    • (2009) Int J Cancer , vol.125 , pp. 774-782
    • Xiong, S.D.1    Yu, K.2    Liu, X.H.3    Yin, L.H.4    Kirschenbaum, A.5    Yao, S.6
  • 12
    • 77956538443 scopus 로고    scopus 로고
    • Crystallization and preliminary X-ray studies of a galactose-specific lectin from the seeds of bitter gourd (Momordica charantia)
    • Chandran T, Sharma A, Vijayan M. Crystallization and preliminary X-ray studies of a galactose-specific lectin from the seeds of bitter gourd (Momordica charantia). Acta Crystallogr Sect F Struct Biol Cryst Commun 2010;66:1037-40.
    • (2010) Acta Crystallogr Sect F Struct Biol Cryst Commun , vol.66 , pp. 1037-1040
    • Chandran, T.1    Sharma, A.2    Vijayan, M.3
  • 13
    • 0018884529 scopus 로고
    • Inhibition of protein synthesis in vitro by proteins from the seeds of Momordica charantia (bitter pear melon)
    • Barbieri L, Zamboni M, Lorenzoni E, Montanaro L, Sperti S, Stirpe F. Inhibition of protein synthesis in vitro by proteins from the seeds of Momordica charantia (bitter pear melon). Biochem J 1980;186:443-52. (Pubitemid 10097485)
    • (1980) Biochemical Journal , vol.186 , Issue.2 , pp. 443-452
    • Barbieri, L.1    Zamboni, M.2    Lorenzoni, E.3
  • 14
    • 77249112249 scopus 로고    scopus 로고
    • A lectin with anti-HIV-1 reverse transcriptase, antitumor, and nitric oxide inducing activities from seeds of Phaseolus vulgaris cv. extralong autumn purple bean
    • Fang EF, Lin P, Wong JH, Tsao SW, Ng TB. A lectin with anti-HIV-1 reverse transcriptase, antitumor, and nitric oxide inducing activities from seeds of Phaseolus vulgaris cv. extralong autumn purple bean. J Agric Food Chem 2010;58:2221-9.
    • (2010) J Agric Food Chem , vol.58 , pp. 2221-2229
    • Fang, E.F.1    Lin, P.2    Wong, J.H.3    Tsao, S.W.4    Ng, T.B.5
  • 15
    • 82355187576 scopus 로고    scopus 로고
    • A new Phaseolus vulgaris lectin induces selective toxicity on human liver carcinoma Hep G2 cells
    • Mar 29. Epub ahead of print
    • Fang EF, Pan WL, Wong JH, Chan YS, Ye XJ, Ng TB. A new Phaseolus vulgaris lectin induces selective toxicity on human liver carcinoma Hep G2 cells. Arch Toxicol 2011 Mar 29. [Epub ahead of print].
    • (2011) Arch Toxicol
    • Fang, E.F.1    Pan, W.L.2    Wong, J.H.3    Chan, Y.S.4    Ye, X.J.5    Ng, T.B.6
  • 16
    • 70350113625 scopus 로고    scopus 로고
    • ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway
    • Hu ZY, Sun J, Zhu XF, Yang D, Zeng YX. ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway. J Transl Med 2009;7:74.
    • (2009) J Transl Med , vol.7 , pp. 74
    • Hu, Z.Y.1    Sun, J.2    Zhu, X.F.3    Yang, D.4    Zeng, Y.X.5
  • 17
    • 0027374638 scopus 로고
    • A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro- 1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1)
    • DOI 10.1006/bbrc.1993.2438
    • Cossarizza A, Baccarani-Contri M, Kalashnikova G, Franceschi C. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5′,6,6′- tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem Biophys Res Commun 1993;197:40-5. (Pubitemid 23358874)
    • (1993) Biochemical and Biophysical Research Communications , vol.197 , Issue.1 , pp. 40-45
    • Cossarizza, A.1    Baccarani-Contri, M.2    Kalashnikova, G.3    Franceschi, C.4
  • 18
    • 80051547554 scopus 로고    scopus 로고
    • Trichostatin A sensitizes HBx-expressing liver cancer cells to etoposide treatment
    • Zhang CZ, Zhang HT, Chen GG, Lai PB. Trichostatin A sensitizes HBx-expressing liver cancer cells to etoposide treatment. Apoptosis 2011;16:683-95.
    • (2011) Apoptosis , vol.16 , pp. 683-695
    • Zhang, C.Z.1    Zhang, H.T.2    Chen, G.G.3    Lai, P.B.4
  • 19
    • 77953937449 scopus 로고    scopus 로고
    • The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo
    • Dasmahapatra G, Lembersky D, Kramer L, Fisher RI, Friedberg J, Dent P, et al. The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo. Blood 2010;115:4478-87.
    • (2010) Blood , vol.115 , pp. 4478-4487
    • Dasmahapatra, G.1    Lembersky, D.2    Kramer, L.3    Fisher, R.I.4    Friedberg, J.5    Dent, P.6
  • 20
    • 0022530497 scopus 로고
    • Isolation and characterization of a galactose binding lectin with insulinomimetic activities. From the seeds of the bitter gourd Momordica charantia (Family Cucurbitaceae)
    • Ng TB, Wong CM, Li WW, Yeung HW. Isolation and characterization of a galactose binding lectin with insulinomimetic activities. From the seeds of the bitter gourdMomordica charantia (Family Cucurbitaceae). Int J Pept Protein Res 1986;28:163-72. (Pubitemid 16012937)
    • (1986) International Journal of Peptide and Protein Research , vol.28 , Issue.2 , pp. 163-172
    • Ng, T.B.1    Wong, C.M.2    Li, W.W.3    Yeung, H.W.4
  • 21
    • 0019484463 scopus 로고
    • The physicochemical properties of the galactose-specific lectin from Momordica charantia
    • Mazumder T, Gaur N, Surolia A. The physicochemical properties of the galactose-specific lectin from Momordica charantia. Eur J Biochem 1981;113:463-70.
    • (1981) Eur J Biochem , vol.113 , pp. 463-470
    • Mazumder, T.1    Gaur, N.2    Surolia, A.3
  • 22
    • 0019406098 scopus 로고
    • Binding of 4- methylumbelliferyl beta-D-galactopyranoside to Momordica charantia lectin: Fluorescence-quenching studies
    • Khan MI, Mazumder T, Pain D, Gaur N, Surolia A. Binding of 4- methylumbelliferyl beta-D-galactopyranoside to Momordica charantia lectin: fluorescence-quenching studies. Eur J Biochem 1981;113:471-6.
    • (1981) Eur J Biochem , vol.113 , pp. 471-476
    • Khan, M.I.1    Mazumder, T.2    Pain, D.3    Gaur, N.4    Surolia, A.5
  • 23
    • 72449179457 scopus 로고    scopus 로고
    • Molecular characterization of a galactose- binding lectin from Momordica charantia seeds and its expression in tobacco cells
    • Tanaka H, Toyama J, Akashi R. Molecular characterization of a galactose- binding lectin from Momordica charantia seeds and its expression in tobacco cells. Asian J Plant Sci 2009;8:544-50.
    • (2009) Asian J Plant Sci , vol.8 , pp. 544-550
    • Tanaka, H.1    Toyama, J.2    Akashi, R.3
  • 24
    • 63849246525 scopus 로고    scopus 로고
    • Protein structure prediction on the Web: A case study using the Phyre server
    • Kelley LA, Sternberg MJ. Protein structure prediction on the Web: a case study using the Phyre server. Nat Protoc 2009;4:363-71.
    • (2009) Nat Protoc , vol.4 , pp. 363-371
    • Kelley, L.A.1    Sternberg, M.J.2
  • 25
    • 0037457286 scopus 로고    scopus 로고
    • Troglitazone but not rosiglitazone induces G1 cell cycle arrest and apoptosis in human and rat hepatoma cell lines
    • DOI 10.1016/S0378-4274(02)00468-X
    • Bae MA, Rhee H, Song BJ. Troglitazone but not rosiglitazone induces G1 cell cycle arrest and apoptosis in human and rat hepatoma cell lines. Toxicol Lett 2003;139:67-75. (Pubitemid 36197848)
    • (2003) Toxicology Letters , vol.139 , Issue.1 , pp. 67-75
    • Bae, M.-A.1    Rhee, H.2    Song, B.J.3
  • 26
    • 36048952664 scopus 로고    scopus 로고
    • Grifolin, a potential antitumor natural product from the mushroom Albatrellus confluens, induces cell-cycle arrest in G1 phase via the ERK1/2 pathway
    • DOI 10.1016/j.canlet.2007.09.001, PII S0304383507004107
    • Ye M, Luo X, Li L, Shi Y, Tan M, Weng X, et al. Grifolin, a potential antitumor natural product from the mushroom Albatrellus confluens, induces cell-cycle arrest in G1 phase via the ERK1/2 pathway. Cancer Lett 2007;258:199-207. (Pubitemid 350101018)
    • (2007) Cancer Letters , vol.258 , Issue.2 , pp. 199-207
    • Ye, M.1    Luo, X.2    Li, L.3    Shi, Y.4    Tan, M.5    Weng, X.6    Li, W.7    Liu, J.8    Cao, Y.9
  • 28
    • 0035282334 scopus 로고    scopus 로고
    • MammalianMAPkinase signalling cascades
    • Chang L, Karin M. MammalianMAPkinase signalling cascades. Nature 2001;410:37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 29
    • 4544292313 scopus 로고    scopus 로고
    • D1 dopamine receptor mediates dopamine-induced cytotoxicity via the ERK signal cascade
    • DOI 10.1074/jbc.M403891200
    • Chen J, Rusnak M, Luedtke RR, Sidhu A. D1 dopamine receptor mediates dopamine-induced cytotoxicity via the ERK signal cascade. J Biol Chem 2004;279:39317-30. (Pubitemid 39258194)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.38 , pp. 39317-39330
    • Chen, J.1    Rusnak, M.2    Luedtke, R.R.3    Sidhu, A.4
  • 30
    • 23744465712 scopus 로고    scopus 로고
    • Trichosanthin inhibits antigen-specific T cell expansion through nitric oxide-mediated apoptosis pathway
    • DOI 10.1016/j.cellimm.2005.04.015, PII S0008874905000687
    • Li F, Mei Y, Wang Y, Chen C, Tu J, Xiao B, et al. Trichosanthin inhibits antigen-specific T cell expansion through nitric oxide-mediated apoptosis pathway. Cell Immunol 2005;234:23-30. (Pubitemid 41140388)
    • (2005) Cellular Immunology , vol.234 , Issue.1 , pp. 23-30
    • Li, F.1    Mei, Y.2    Wang, Y.3    Chen, C.4    Tu, J.5    Xiao, B.6    Xu, L.7
  • 31
    • 0032608756 scopus 로고    scopus 로고
    • Time- and concentration-dependent production of superoxide anion, nitric oxide, DNA damage and cellular death by ricin in the J774A.1 macrophage cells
    • Hassoun EA, Wang X. Time- and concentration-dependent production of superoxide anion, nitric oxide, DNA damage and cellular death by ricin in the J774A.1 macrophage cells. J Biochem Mol Toxicol 1999;13:179-85. (Pubitemid 129705390)
    • (1999) Journal of Biochemical and Molecular Toxicology , vol.13 , Issue.3-4 , pp. 179-185
    • Hassoun, E.A.1    Wang, X.2
  • 33
    • 8444220527 scopus 로고    scopus 로고
    • Molecular mechanisms of caspase regulation during apoptosis
    • DOI 10.1038/nrm1496
    • Riedl SJ, Shi Y. Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 2004;5:897-907. (Pubitemid 39486541)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.11 , pp. 897-907
    • Riedl, S.J.1    Shi, Y.2
  • 34
    • 0034613302 scopus 로고    scopus 로고
    • Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1
    • Jiang X, Wang X. Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1. J Biol Chem 2000;275:31199-203.
    • (2000) J Biol Chem , vol.275 , pp. 31199-31203
    • Jiang, X.1    Wang, X.2
  • 37
    • 78149280601 scopus 로고    scopus 로고
    • Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma
    • Louis CU, Straathof K, Bollard CM, Ennamuri S, Gerken C, Lopez TT, et al. Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma. J Immunother 2010;33:983-90.
    • (2010) J Immunother , vol.33 , pp. 983-990
    • Louis, C.U.1    Straathof, K.2    Bollard, C.M.3    Ennamuri, S.4    Gerken, C.5    Lopez, T.T.6
  • 38
    • 78449255989 scopus 로고    scopus 로고
    • miR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling
    • Xia H, Cheung WK, Sze J, Lu G, Jiang S, Yao H, et al. miR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling. J Biol Chem 2010;285:36995-7004.
    • (2010) J Biol Chem , vol.285 , pp. 36995-37004
    • Xia, H.1    Cheung, W.K.2    Sze, J.3    Lu, G.4    Jiang, S.5    Yao, H.6
  • 39
    • 78650630361 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis of human nasopharyngeal carcinoma cells via activation of multiple apoptotic pathways
    • Huang TT, Lin HC, Chen CC, Lu CC, Wei CF, Wu TS, et al. Resveratrol induces apoptosis of human nasopharyngeal carcinoma cells via activation of multiple apoptotic pathways. J Cell Physiol 2011;226:720-8.
    • (2011) J Cell Physiol , vol.226 , pp. 720-728
    • Huang, T.T.1    Lin, H.C.2    Chen, C.C.3    Lu, C.C.4    Wei, C.F.5    Wu, T.S.6
  • 40
    • 77956405785 scopus 로고    scopus 로고
    • Chk1 inhibitor Go6976 enhances the sensitivity of nasopharyngeal carcinoma cells to radiotherapy and chemotherapy in vitro and in vivo
    • Feng Z, Xu S, Liu M, Zeng YX, Kang T. Chk1 inhibitor Go6976 enhances the sensitivity of nasopharyngeal carcinoma cells to radiotherapy and chemotherapy in vitro and in vivo. Cancer Lett 2010;297:190-7.
    • (2010) Cancer Lett , vol.297 , pp. 190-197
    • Feng, Z.1    Xu, S.2    Liu, M.3    Zeng, Y.X.4    Kang, T.5
  • 41
    • 84855522943 scopus 로고    scopus 로고
    • Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells
    • Lui VW, Lau CP, Ho K, Ng MH, Cheng SH, Tsao SW, et al. Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells. Invest New Drugs 2011;29:1241-52.
    • (2011) Invest New Drugs , vol.29 , pp. 1241-1252
    • Lui, V.W.1    Lau, C.P.2    Ho, K.3    Ng, M.H.4    Cheng, S.H.5    Tsao, S.W.6
  • 42
    • 0020385029 scopus 로고
    • Monoclonal anti-MM46 antibody:Ricin A chain conjugate: In vitro and in vivo antitumor activity
    • Seto M, Umemoto N, Saito M, Masuho Y, Hara T, Takahashi T. Monoclonal anti-MM46 antibody:ricin A chain conjugate: in vitro and in vivo antitumor activity. Cancer Res 1982;42:5209-15. (Pubitemid 13223170)
    • (1982) Cancer Research , vol.42 , Issue.12 , pp. 5209-5215
    • Seto, M.1    Umemoto, N.2    Saito, M.3
  • 43
    • 7244258916 scopus 로고    scopus 로고
    • History of lectins: From hemagglutinins to biological recognition molecules
    • DOI 10.1093/glycob/cwh122
    • Sharon N, Lis H. History of lectins: from hemagglutinins to biological recognition molecules. Glycobiology 2004;14:53R-62R. (Pubitemid 39430025)
    • (2004) Glycobiology , vol.14 , Issue.11
    • Sharon, N.1    Lis, H.2
  • 44
    • 0033539067 scopus 로고    scopus 로고
    • Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation
    • DOI 10.1038/43678
    • Sahara S, Aoto M, Eguchi Y, Imamoto N, Yoneda Y, Tsujimoto Y. Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation. Nature 1999;401:168-73. (Pubitemid 29436320)
    • (1999) Nature , vol.401 , Issue.6749 , pp. 168-173
    • Sahara, S.1    Aoto, M.2    Eguchi, Y.3    Imamoto, N.4    Yoneda, Y.5    Tsujimoto, Y.6
  • 47
    • 0031596491 scopus 로고    scopus 로고
    • 1 arrest results from p21-independent disruption of retinoblastoma protein-mediated signals
    • Vaziri C, Stice L, Faller DV. Butyrate-induced G1 arrest results from p21-independent disruption of retinoblastoma protein-mediated signals. Cell Growth Differ 1998;9:465-74. (Pubitemid 28345871)
    • (1998) Cell Growth and Differentiation , vol.9 , Issue.6 , pp. 465-474
    • Vaziri, C.1    Stice, L.2    Faller, D.V.3
  • 48
    • 33644970995 scopus 로고    scopus 로고
    • 14-3-3Sigma, a p53 regulator, suppresses tumor growth of nasopharyngeal carcinoma
    • Yang H, Zhao R, Lee MH. 14-3-3sigma, a p53 regulator, suppresses tumor growth of nasopharyngeal carcinoma. Mol Cancer Ther 2006;5: 253-60.
    • (2006) Mol Cancer Ther , vol.5 , pp. 253-260
    • Yang, H.1    Zhao, R.2    Lee, M.H.3
  • 50
    • 0033974883 scopus 로고    scopus 로고
    • Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia
    • Cai X, Shen YL, Zhu Q, Jia PM, Yu Y, Zhou L, et al. Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia. Leukemia 2000;14:262-70. (Pubitemid 30095381)
    • (2000) Leukemia , vol.14 , Issue.2 , pp. 262-270
    • Cai, X.1    Shen, Y.-L.2    Zhu, Q.3    Jia, P.-M.4    Yu, Y.5    Zhou, L.6    Huang, Y.7    Zhang, J.-W.8    Xiong, S.-M.9    Chen, S.-J.10    Wang, Z.-Y.11    Chen, Z.12    Chen, G.-Q.13
  • 51
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, aBcl2 interacting protein,mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998;94:481-90. (Pubitemid 28391864)
    • (1998) Cell , vol.94 , Issue.4 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 52
    • 0038079767 scopus 로고    scopus 로고
    • CIP1/WAF1
    • Rosato RR, Almenara JA, Grant S. The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1. Cancer Res 2003;63:3637-45. (Pubitemid 36793047)
    • (2003) Cancer Research , vol.63 , Issue.13 , pp. 3637-3645
    • Rosato, R.R.1    Almenara, J.A.2    Grant, S.3
  • 54
    • 0023689869 scopus 로고
    • Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A-chain and hindered disulfide linkages
    • Thorpe PE, Wallace PM, Knowles PP, Relf MG, Brown AN, Watson GJ, et al. Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A-chain and hindered disulfide linkages. Cancer Res 1988;48:6396-403.
    • (1988) Cancer Res , vol.48 , pp. 6396-6403
    • Thorpe, P.E.1    Wallace, P.M.2    Knowles, P.P.3    Relf, M.G.4    Brown, A.N.5    Watson, G.J.6
  • 55
    • 78650539904 scopus 로고    scopus 로고
    • Ribonucleases of different origins with a wide spectrum of medicinal applications
    • Fang EF, Ng TB. Ribonucleases of different origins with a wide spectrum of medicinal applications. Biochim Biophys Acta-Rev Cancer 2011;1815:65-74.
    • (2011) Biochim Biophys Acta-Rev Cancer , vol.1815 , pp. 65-74
    • Fang, E.F.1    Ng, T.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.