Spiroquinazolinone-Induced cytotoxicity and apoptosis in k562 human leukemia cells: Alteration in expression levels of bcl-2 and bax

Journal of Toxicological Sciences

Volumn 40, Issue 1, 2015, Pages 115-126

  Mahdavi, Majid ^a   Ghasemian, Majid ^a   Zare, Payman ^a   Feizi, Mohammad Ali Hosseinpour ^a  

^a UNIVERSITY OF TABRIZ   (Iran)

Author keywords

Apoptosis; Bax; Bcl 2; Caspase 3; Chronic Myeloid leukemia; Spiroquinazolinone

Indexed keywords

ACRIDINE ORANGE; ANTINEOPLASTIC AGENT; CASPASE 3; ETHIDIUM BROMIDE; PROTEIN BAX; PROTEIN BCL 2; SPIROQUINAZOLINONE; UNCLASSIFIED DRUG; BAX PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; SPIRO COMPOUND; SPIROQUINAZOLINE;

APOPTOSIS; ARTICLE; CELL CYCLE ASSAY; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION ASSAY; DOWN REGULATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MTT ASSAY; MUTATION; PHASE CONTRAST MICROSCOPY; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; K562 CELL LINE; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; METABOLISM; PATHOLOGY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; K562 CELLS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; PROTO-ONCOGENE PROTEINS C-BCL-2; SPIRO COMPOUNDS;

EID: 84923288709     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.40.115     Document Type: Article

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