Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family

Biomedicine and Pharmacotherapy

Volumn 65, Issue 3, 2011, Pages 175-182

  Mahdavi, Majid ^a   Davoodi, Jamshid ^a   Zali, Mohammad Reza ^b   Foroumadi, Alireza ^c  

^a UNIVERSITY OF TEHRAN   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

4 aryl 4H chromenes; Apoptosis; Caspase 9; CIAP2; Survivin; XIAP

Indexed keywords

2 AMINO 3 CYANO 7 (DIMETHYLAMINO) 4 (3 NITROPHENYL) 4H CHROMENE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; CASPASE 9; CELLULAR INHIBITOR OF APOPTOSIS PROTEIN 2; CHROMENE DERIVATIVE; DNA; INHIBITOR OF APOPTOSIS PROTEIN; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL DEATH; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL SURVIVAL; CELL VIABILITY; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; IC 50; PRIORITY JOURNAL; WESTERN BLOTTING;

ANILIDES; ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZOPYRANS; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; CELL PROLIFERATION; DIOXOLES; DOWN-REGULATION; ENZYME ACTIVATION; HCT116 CELLS; HEP G2 CELLS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; OLIGOPEPTIDES; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 79959629794     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2011.03.001     Document Type: Article

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