Molecular basis for structural heterogeneity of an intrinsically disordered protein bound to a partner by combined ESI-IM-MS and modeling

Journal of the American Society for Mass Spectrometry

Volumn 26, Issue 3, 2015, Pages 472-481

  D'Urzo, Annalisa ^a   Konijnenberg, Albert ^b   Rossetti, Giulia ^c   Habchi, Johnny ^d,e   Li, Jinyu ^c,f   Carloni, Paolo ^c   Sobott, Frank ^b   Longhi, Sonia ^d,e   Grandori, Rita ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

^d AIX MARSEILLE UNIVERSITY   (France)

^e CNRS   (France)

^f RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Conformational ensemble; Hydrophobic Interactions; Ion mobility; Measles virus; Native mass spectrometry; Ntail Pxd complex

Indexed keywords

ELECTRODEPOSITION; ELECTROSPRAY IONIZATION; GASES; HYDROPHOBICITY; IONIZATION OF GASES; PROTEINS; SPECTROMETRY; VIRUSES;

CONFORMATIONAL ENSEMBLE; HYDROPHOBIC INTERACTIONS; ION MOBILITY; MEASLES VIRUS; NATIVE MASS SPECTROMETRIES; NTAIL-PXD COMPLEX;

MASS SPECTROMETRY;

ACETONITRILE; AMMONIUM ACETATE; FORMIC ACID; INTRINSICALLY DISORDERED PROTEIN; PHOSPHOPROTEIN; RECOMBINANT PROTEIN; VIRUS PROTEIN;

ARTICLE; ELECTROSPRAY MASS SPECTROMETRY; HYDROGEN BOND; ION MOBILITY SPECTROMETRY; MATHEMATICAL MODEL; MEASLES VIRUS; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STATIC ELECTRICITY; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; PROCEDURES; PROTEIN CONFORMATION;

MEASLES VIRUS;

HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INTRINSICALLY DISORDERED PROTEINS; MEASLES VIRUS; MODELS, MOLECULAR; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; VIRAL PROTEINS;

EID: 84923285656     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-014-1048-z     Document Type: Article

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