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Volumn 10, Issue 2, 2015, Pages

OVCAR-3 spheroid-derived cells display distinct metabolic profiles

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ARGININE; ASPARTIC ACID; BIOLOGICAL MARKER; ERYTHRONIC ACID; FUMARIC ACID; GLUTAMIC ACID; ISOLEUCINE; PROLINE; PSICOSE; PUTRESCINE; PYROPHOSPHATE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; URIDINE PHOSPHATE;

EID: 84923280721     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118262     Document Type: Article
Times cited : (29)

References (65)
  • 2
    • 9344235023 scopus 로고    scopus 로고
    • Recurrent ovarian cancer: How important is it to treat to disease progression?
    • PMID: 15569973
    • Herzog TJ. Recurrent Ovarian Cancer: How Important Is It to Treat to Disease Progression? Clinical Cancer Research. 2004;10(22):7439-49. doi: 10.1158/1078-0432. CCR-04-0683 PMID: 15569973
    • (2004) Clinical Cancer Research. , vol.10 , Issue.22 , pp. 7439-7449
    • Herzog, T.J.1
  • 3
    • 74749089142 scopus 로고    scopus 로고
    • The role of cancer stem cells and the side population in epithelial ovarian cancer
    • PMID: 19924647
    • Fong MY, Kakar SS. The role of cancer stem cells and the side population in epithelial ovarian cancer. Histology and Histopathology. 2010;25(1):113-20. PMID: 19924647
    • (2010) Histology and Histopathology , vol.25 , Issue.1 , pp. 113-120
    • Fong, M.Y.1    Kakar, S.S.2
  • 4
    • 70149124370 scopus 로고    scopus 로고
    • Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3
    • PMID: 19728235
    • Gao Q L, Geng L, Kvalheim G, Gaudernack G, Suo ZH. Identification of Cancer Stem-like Side Population Cells in Ovarian Cancer Cell Line OVCAR-3. Ultrastruct Pathol. 2009;33(4):175-81. doi: 10.1080/01913120903086072 PMID: 19728235
    • (2009) Ultrastruct Pathol. , vol.33 , Issue.4 , pp. 175-181
    • Gao, Q.L.1    Geng, L.2    Kvalheim, G.3    Gaudernack, G.4    Suo, Z.H.5
  • 5
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • PMID: 8666936
    • Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med. 1996;183(4):1797-806. PMID: 8666936
    • (1996) J Exp Med. , vol.183 , Issue.4 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 6
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • PMID: 18784658
    • Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer. 2008;8(10):755-68. doi: 10.1038/nrc2499 PMID: 18784658
    • (2008) Nat Rev Cancer. , vol.8 , Issue.10 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 7
    • 60749103183 scopus 로고    scopus 로고
    • Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance
    • 7533 PMID: 19158483
    • Alvero AB, Chen R, Fu HH, Montagna M, Schwartz PE, Rutherford T, et al. Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance. Cell cycle. 2009;8(1):158-66. 7533 [pii]. PMID: 19158483
    • (2009) Cell Cycle. , vol.8 , Issue.1 , pp. 158-166
    • Alvero, A.B.1    Chen, R.2    Fu, H.H.3    Montagna, M.4    Schwartz, P.E.5    Rutherford, T.6
  • 8
    • 84857903344 scopus 로고    scopus 로고
    • Isolation and characterization of stemlike cells from a human ovarian cancer cell line
    • PMID: 22231842
    • Wang L, Mezencev R, Bowen NJ, Matyunina LV, McDonald JF. Isolation and characterization of stemlike cells from a human ovarian cancer cell line. MolCell Biochem. 2012;363(1-2):257-68. doi: 10. 1007/s11010-011-1178-6 PMID: 22231842
    • (2012) MolCell Biochem. , vol.363 , Issue.1-2 , pp. 257-268
    • Wang, L.1    Mezencev, R.2    Bowen, N.J.3    Matyunina, L.V.4    McDonald, J.F.5
  • 9
    • 72049125350 scopus 로고    scopus 로고
    • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
    • PMID: 19935646
    • Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 2009;462(7274):739-U52. doi: 10.1038/nature08617 PMID: 19935646
    • (2009) Nature. , vol.462 , Issue.7274 , pp. 739-U52
    • Dang, L.1    White, D.W.2    Gross, S.3    Bennett, B.D.4    Bittinger, M.A.5    Driggers, E.M.6
  • 10
    • 84861420588 scopus 로고    scopus 로고
    • Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation
    • PMID: 22628656
    • Jain M, Nilsson R, Sharma S, Madhusudhan N, Kitami T, Souza A L, et al. Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. Science. 2012;336(6084):1040-4. doi: 10.1126/science.1218595 PMID: 22628656
    • (2012) Science. , vol.336 , Issue.6084 , pp. 1040-1044
    • Jain, M.1    Nilsson, R.2    Sharma, S.3    Madhusudhan, N.4    Kitami, T.5    Souza, A.L.6
  • 11
    • 77956508105 scopus 로고    scopus 로고
    • Rapid mass spectrometric metabolic profiling of blood sera detects ovarian cancer with high accuracy
    • PMID: 25613532
    • Zhou M, Guan W, Walker LD, Mezencev R, Benigno BB, Gray A, et al. Rapid Mass Spectrometric Metabolic Profiling of Blood Sera Detects Ovarian Cancer with High Accuracy. Cancer Epidemiology Biomarkers & Prevention. 2010;19 (9:). doi: 10.1158/1055-9965.epi-10-0126 PMID: 25613532
    • (2010) Cancer Epidemiology Biomarkers & Prevention , vol.19 , Issue.9
    • Zhou, M.1    Guan, W.2    Walker, L.D.3    Mezencev, R.4    Benigno, B.B.5    Gray, A.6
  • 12
    • 84874067623 scopus 로고    scopus 로고
    • Identification of potential biomarkers for ovarian cancer by urinary metabolomic profiling
    • PMID: 23163809
    • Zhang T, Wu X, Ke C, Yin M, Li Z, Fan L, et al. Identification of Potential Biomarkers for Ovarian Cancer by Urinary Metabolomic Profiling. J Proteome Res. 2013;12(1):505-12. doi: 10.1021/pr3009572 PMID: 23163809
    • (2013) J Proteome Res. , vol.12 , Issue.1 , pp. 505-512
    • Zhang, T.1    Wu, X.2    Ke, C.3    Yin, M.4    Li, Z.5    Fan, L.6
  • 13
    • 84904133341 scopus 로고    scopus 로고
    • Metformin against cancer stem cells through the modulation of energy metabolism: Special considerations on ovarian cancer
    • PMID: 25050322
    • Kim TH, Suh DH, Kim MK, Song YS. Metformin against cancer stem cells through the modulation of energy metabolism: special considerations on ovarian cancer. BioMed research international. 2014;2014:132702. doi: 10.1155/2014/132702 PMID: 25050322
    • (2014) BioMed Research International , vol.2014 , pp. 132702
    • Kim, T.H.1    Suh, D.H.2    Kim, M.K.3    Song, Y.S.4
  • 14
    • 84923227126 scopus 로고    scopus 로고
    • The metabolic state of cancer stem cells - A valid target for cancer therapy?
    • Vlashi E, Pajonk F. The metabolic state of cancer stem cells-a valid target for cancer therapy? Free radical biology & medicine. 2014. doi: 10.1016/j.freeradbiomed.2014.10.732.
    • (2014) Free Radical Biology & Medicine
    • Vlashi, E.1    Pajonk, F.2
  • 15
    • 84900296103 scopus 로고    scopus 로고
    • Targeting lactate dehydrogenase - A inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells
    • PMID: 24726384
    • Xie H, Hanai J, Ren JG, Kats L, Burgess K, Bhargava P, et al. Targeting lactate dehydrogenase-a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells. Cell metabolism. 2014;19(5):795-809. doi: 10.1016/j.cmet.2014.03.003 PMID: 24726384
    • (2014) Cell Metabolism , vol.19 , Issue.5 , pp. 795-809
    • Xie, H.1    Hanai, J.2    Ren, J.G.3    Kats, L.4    Burgess, K.5    Bhargava, P.6
  • 16
    • 84858867303 scopus 로고    scopus 로고
    • In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla
    • PMID: 21796713
    • Mlynarik V, Cudalbu C, Clement V, Marino D, Radovanovic I, Gruetter R. In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla. NMRin biomedicine. 2012;25(4):506-13. doi: 10.1002/nbm.1763 PMID: 21796713
    • (2012) NMRin Biomedicine , vol.25 , Issue.4 , pp. 506-513
    • Mlynarik, V.1    Cudalbu, C.2    Clement, V.3    Marino, D.4    Radovanovic, I.5    Gruetter, R.6
  • 17
    • 84905513845 scopus 로고    scopus 로고
    • Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment
    • PMID: 25616257
    • Ciavardelli D, Rossi C, Barcaroli D, Volpe S, Consalvo A, Zucchelli M, et al. Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment. Cell death & disease. 2014;5:e1336. doi: 10.1038/cddis.2014.285 PMID: 25616257
    • (2014) Cell Death & Disease , vol.5 , pp. e1336
    • Ciavardelli, D.1    Rossi, C.2    Barcaroli, D.3    Volpe, S.4    Consalvo, A.5    Zucchelli, M.6
  • 18
    • 84919638312 scopus 로고    scopus 로고
    • CD133-positive cancer stem cells from Colo205 human colon adenocarcinoma cell line show resistance to chemotherapy and display a specific metabolomic profile
    • PMID: 25616260
    • Vincent Z, Urakami K, Maruyama K, Yamaguchi K, Kusuhara M. CD133-positive cancer stem cells from Colo205 human colon adenocarcinoma cell line show resistance to chemotherapy and display a specific metabolomic profile. Genes & cancer. 2014;5(7-8):250-60. doi: 10.1016/j.micpath.2015.01. 006 PMID: 25616260
    • (2014) Genes & Cancer , vol.5 , Issue.7-8 , pp. 250-260
    • Vincent, Z.1    Urakami, K.2    Maruyama, K.3    Yamaguchi, K.4    Kusuhara, M.5
  • 20
    • 84902587472 scopus 로고    scopus 로고
    • Targeting unique metabolic properties of breast tumor initiating cells
    • PMID: 24497069
    • Feng W, Gentles A, Nair RV, Huang M, Lin Y, Lee CY, et al. Targeting unique metabolic properties of breast tumor initiating cells. Stem cells. 2014;32(7):1734-45. doi: 10.1002/stem.1662 PMID: 24497069
    • (2014) Stem Cells , vol.32 , Issue.7 , pp. 1734-1745
    • Feng, W.1    Gentles, A.2    Nair, R.V.3    Huang, M.4    Lin, Y.5    Lee, C.Y.6
  • 21
    • 84905041477 scopus 로고    scopus 로고
    • Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine
    • PMID: 25015789
    • Isayev O, Rausch V, Bauer N, Liu L, Fan P, Zhang Y, et al. Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine. Oncotarget. 2014;5(13):5177-89. PMID: 25015789
    • (2014) Oncotarget. , vol.5 , Issue.13 , pp. 5177-5189
    • Isayev, O.1    Rausch, V.2    Bauer, N.3    Liu, L.4    Fan, P.5    Zhang, Y.6
  • 22
    • 84896965787 scopus 로고    scopus 로고
    • Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolism
    • PMID: 24409314
    • Liao J, Qian F, Tchabo N, Mhawech-Fauceglia P, Beck A, Qian Z, et al. Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolism. PLoSOne. 2014;9(1):e84941. doi: 10.1371/journal.pone. 0084941 PMID: 24409314
    • (2014) PLoSOne , vol.9 , Issue.1 , pp. e84941
    • Liao, J.1    Qian, F.2    Tchabo, N.3    Mhawech-Fauceglia, P.4    Beck, A.5    Qian, Z.6
  • 23
    • 84890118522 scopus 로고    scopus 로고
    • Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway
    • PMID: 24096870
    • Liu PP, Liao J, Tang Z J, Wu WJ, Yang J, Zeng ZL, et al. Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway. Cell death and differentiation. 2014;21(1):124-35. doi: 10.1038/cdd.2013.131 PMID: 24096870
    • (2014) Cell Death and Differentiation , vol.21 , Issue.1 , pp. 124-135
    • Liu, P.P.1    Liao, J.2    Tang, Z.J.3    Wu, W.J.4    Yang, J.5    Zeng, Z.L.6
  • 25
    • 84921860188 scopus 로고    scopus 로고
    • Metabolic reprogramming orchestrates cancer stem cell properties in nasopharyngeal carcinoma
    • Shen YA, Wang CY, Hsieh YT, Chen YJ, Wei YH. Metabolic Reprogramming Orchestrates Cancer Stem Cell Properties in Nasopharyngeal Carcinoma. Cell cycle. 2014:0. doi: 10.4161/15384101.2014. 974419.
    • (2014) Cell Cycle , pp. 0
    • Shen, Y.A.1    Wang, C.Y.2    Hsieh, Y.T.3    Chen, Y.J.4    Wei, Y.H.5
  • 27
    • 84907598112 scopus 로고    scopus 로고
    • Metabolic differences in breast cancer stem cells and differentiated progeny
    • PMID: 25007966
    • Vlashi E, Lagadec C, Vergnes L, Reue K, Frohnen P, Chan M, et al. Metabolic differences in breast cancer stem cells and differentiated progeny. Breast cancer research and treatment. 2014;146(3):525-34. doi: 10.1007/s10549-014-3051-2 PMID: 25007966
    • (2014) Breast Cancer Research and Treatment , vol.146 , Issue.3 , pp. 525-534
    • Vlashi, E.1    Lagadec, C.2    Vergnes, L.3    Reue, K.4    Frohnen, P.5    Chan, M.6
  • 29
    • 84892562110 scopus 로고    scopus 로고
    • Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets
    • PMID: 24200964
    • Cipolleschi MG, Marzi I, Santini R, Fredducci D, Vinci MC, D'Amico M, et al. Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets. Cell cycle. 2014;13(2):268-78. doi: 10.4161/cc.27031 PMID: 24200964
    • (2014) Cell Cycle , vol.13 , Issue.2 , pp. 268-278
    • Cipolleschi, M.G.1    Marzi, I.2    Santini, R.3    Fredducci, D.4    Vinci, M.C.5    D'Amico, M.6
  • 30
    • 84876971340 scopus 로고    scopus 로고
    • Sub-sets of cancer stem cells differ intrinsically in their patterns of oxygen metabolism
    • PMID: 23638097
    • Gammon L, Biddle A, Heywood HK, Johannessen AC, Mackenzie IC. Sub-sets of cancer stem cells differ intrinsically in their patterns of oxygen metabolism. PLoSOne. 2013;8(4):e62493. doi: 10.1371/journal.pone.0062493 PMID: 23638097
    • (2013) PLoSOne , vol.8 , Issue.4 , pp. e62493
    • Gammon, L.1    Biddle, A.2    Heywood, H.K.3    Johannessen, A.C.4    Mackenzie, I.C.5
  • 31
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • PMID: 21376230
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-74. S0092-8674 (11) 00127-9 [pii]. doi: 10.1016/j.cell.2011.02.013 PMID: 21376230
    • (2011) Cell. , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 32
    • 0021058774 scopus 로고
    • Characterization of a human ovarian carcinoma cell line (NIH: OVCAR-3) with androgen and estrogen receptors
    • PMID: 6604576
    • Hamilton TC, Young RC, McKoy WM, Grotzinger KR, Green JA, Chu EW, et al. Characterization of a human ovarian carcinoma cell line (NIH: OVCAR-3) with androgen and estrogen receptors. Cancer research. 1983;43(11):5379-89. PMID: 6604576
    • (1983) Cancer Research , vol.43 , Issue.11 , pp. 5379-5389
    • Hamilton, T.C.1    Young, R.C.2    McKoy, W.M.3    Grotzinger, K.R.4    Green, J.A.5    Chu, E.W.6
  • 33
    • 77951242628 scopus 로고    scopus 로고
    • Metabolomic changes accompanying transformation and acquisition of metastatic potential in a syngeneic mouse mammary tumor model
    • PMID: 20139083
    • Lu X, Bennet B, Mu E, Rabinowitz J, Kang Y. Metabolomic Changes Accompanying Transformation and Acquisition of Metastatic Potential in a Syngeneic Mouse Mammary Tumor Model. J Biol Chem. 2010;285(13):9317-21. doi: 10.1074/jbc. C110.104448 PMID: 20139083
    • (2010) J Biol Chem. , vol.285 , Issue.13 , pp. 9317-9321
    • Lu, X.1    Bennet, B.2    Mu, E.3    Rabinowitz, J.4    Kang, Y.5
  • 34
    • 78650662099 scopus 로고    scopus 로고
    • A simplified liquid chromatography-mass spectrometry assay for artesunate and dihydroartemisinin, its metabolite, in human plasma
    • PMID: 21124272
    • Teja-Isavadharm P, Siriyanonda D, Siripokasupkul R, Apinan R, Chanarat N, Lim A, et al. A Simplified Liquid Chromatography-Mass Spectrometry Assay for Artesunate and Dihydroartemisinin, Its Metabolite, in Human Plasma. Molecules. 2010;15(12):8747-68. doi: 10.3390/molecules15128747 PMID: 21124272
    • (2010) Molecules. , vol.15 , Issue.12 , pp. 8747-8768
    • Teja-Isavadharm, P.1    Siriyanonda, D.2    Siripokasupkul, R.3    Apinan, R.4    Chanarat, N.5    Lim, A.6
  • 35
    • 72449186517 scopus 로고    scopus 로고
    • FiehnLib: Mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography/mass spectrometry
    • PMID: 19928838
    • Kind T, Wohlgemuth G, Lee DY, Lu Y, Palazoglu M, Shahbaz S, et al. FiehnLib: Mass Spectral and Retention Index Libraries for Metabolomics Based on Quadrupole and Time-of-Flight Gas Chromatography/Mass Spectrometry. Anal Chem. 2009;81(24):10038-48. doi: 10.1021/ac9019522 PMID: 19928838
    • (2009) Anal Chem. , vol.81 , Issue.24 , pp. 10038-10048
    • Kind, T.1    Wohlgemuth, G.2    Lee, D.Y.3    Lu, Y.4    Palazoglu, M.5    Shahbaz, S.6
  • 36
    • 84880251002 scopus 로고    scopus 로고
    • MetPP: A computational platform for comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry-based metabolomics
    • PMID: 23665844
    • Wei X, Shi X, Koo I, Kim S, Schmidt RH, Arteel GE, et al. MetPP: a computational platform for comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry-based metabolomics. Bioinformatics (Oxford, England). 2013;29(14):1786-92. doi: 10.1093/bioinformatics/btt275 PMID: 23665844
    • (2013) Bioinformatics (Oxford, England) , vol.29 , Issue.14 , pp. 1786-1792
    • Wei, X.1    Shi, X.2    Koo, I.3    Kim, S.4    Schmidt, R.H.5    Arteel, G.E.6
  • 37
    • 79959913950 scopus 로고    scopus 로고
    • Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
    • PMID: 21720319
    • Dunn WB, Broadhurst D, Begley P, Zelena E, Francis-McIntyre S, Anderson N, et al. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nat Protoc. 2011;6(7):1060-83. doi: 10.1038/nprot.2011.335 PMID: 21720319
    • (2011) Nat Protoc. , vol.6 , Issue.7 , pp. 1060-1083
    • Dunn, W.B.1    Broadhurst, D.2    Begley, P.3    Zelena, E.4    Francis-McIntyre, S.5    Anderson, N.6
  • 38
    • 84864479791 scopus 로고    scopus 로고
    • MetaboAnalyst 2.0 - A comprehensive server for metabolomic data analysis
    • PMID: 22553367
    • Xia JG, Mandal R, Sinelnikov IV, Broadhurst D, Wishart DS. MetaboAnalyst 2.0-a comprehensive server for metabolomic data analysis. Nucleic Acids Research. 2012;40(W1):W127-W33. doi: 10.1093/nar/gks374 PMID: 22553367
    • (2012) Nucleic Acids Research. , vol.40 , Issue.W1 , pp. W127-W33
    • Xia, J.G.1    Mandal, R.2    Sinelnikov, I.V.3    Broadhurst, D.4    Wishart, D.S.5
  • 39
    • 0345688128 scopus 로고    scopus 로고
    • A perspective of polyamine metabolism
    • PMID: 13678416
    • Wallace H, Fraser A, Hughes A. A perspective of polyamine metabolism. Biochem J. 2003;376:1-14. PMID: 13678416
    • (2003) Biochem J. , vol.376 , pp. 1-14
    • Wallace, H.1    Fraser, A.2    Hughes, A.3
  • 41
    • 4944242891 scopus 로고    scopus 로고
    • Polyamines and cancer: Old molecules, new understanding
    • PMID: 15510159
    • Gerner EW, Meyskens FL Jr. Polyamines and cancer: old molecules, new understanding. Nature reviews Cancer. 2004;4(10):781-92. doi: 10.1038/nrc1454 PMID: 15510159
    • (2004) Nature Reviews Cancer. , vol.4 , Issue.10 , pp. 781-792
    • Gerner, E.W.1    Meyskens, F.L.2
  • 42
    • 84896316188 scopus 로고    scopus 로고
    • Polyaminecatabolism in carcinogenesis: Potential targets for chemotherapy and chemoprevention
    • Battaglia V, De Stefano Shields C, Murray-Stewart T, Casero RA. Polyaminecatabolism in carcinogenesis: potential targets for chemotherapy and chemoprevention. Amino Acids. 2013. doi: 10.1007/s00726-013-1529-6.
    • (2013) Amino Acids.
    • Battaglia, V.1    De Stefano Shields, C.2    Murray-Stewart, T.3    Casero, R.A.4
  • 43
    • 34248228763 scopus 로고    scopus 로고
    • Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases
    • PMID: 17464296
    • Casero RA, Marton LJ. Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases. Nature Reviews Drug Discovery. 2007;6(5):373-90. doi: 10.1038/nrd2243 PMID: 17464296
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.5 , pp. 373-390
    • Casero, R.A.1    Marton, L.J.2
  • 44
    • 53849096017 scopus 로고    scopus 로고
    • The metabolism of proline, a stress substrate, modulates carcinogenic pathways
    • PMID: 18401543
    • Phang JM, Donald SP, Pandhare J, Liu Y. The metabolism of proline, a stress substrate, modulates carcinogenic pathways. Amino Acids. 2008;35(4):681-90. doi: 10.1007/s00726-008-0063-4 PMID: 18401543
    • (2008) Amino Acids. , vol.35 , Issue.4 , pp. 681-690
    • Phang, J.M.1    Donald, S.P.2    Pandhare, J.3    Liu, Y.4
  • 45
    • 84875709775 scopus 로고    scopus 로고
    • Bridging epigenetics and metabolism: Role of non-essential amino acids
    • PMID: 23428843
    • Phang JM, Liu W, Hancock C. Bridging epigenetics and metabolism: Role of non-essential amino acids. Epigenetics. 2013;8 (3). doi: 10.4161/epi.24042 PMID: 23428843
    • (2013) Epigenetics. , vol.8 , Issue.3
    • Phang, J.M.1    Liu, W.2    Hancock, C.3
  • 46
    • 84859236400 scopus 로고    scopus 로고
    • Proline metabolism and cancer
    • PMID: 22201839
    • Phang JM, Liu W. Proline metabolism and cancer. Frontiers in Bioscience-Landmark. 2012;17:1835-45. doi: 10.2741/4022 PMID: 22201839
    • (2012) Frontiers in Bioscience-Landmark. , vol.17 , pp. 1835-1845
    • Phang, J.M.1    Liu, W.2
  • 47
    • 84861891911 scopus 로고    scopus 로고
    • Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC
    • PMID: 22615405
    • Liu W, Le A, Hancock C, Lane AN, Dang CV, Fan TW-M, et al. Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC. Proceedings of the National Academy of Sciences. 2012;109(23):8983-8. doi: 10. 1073/pnas.1203244109 PMID: 22615405
    • (2012) Proceedings of the National Academy of Sciences. , vol.109 , Issue.23 , pp. 8983-8988
    • Liu, W.1    Le, A.2    Hancock, C.3    Lane, A.N.4    Dang, C.V.5    Fan, T.W.-M.6
  • 48
    • 77951486317 scopus 로고    scopus 로고
    • L-Proline induces differentiation of ES cells: A novel role for an amino acid in the regulation of pluripotent cells in culture
    • PMID: 20164384
    • Washington JM, Rathjen J, Felquer F, Lonic A, Bettess MD, Hamra N, et al. L-Proline induces differentiation of ES cells: a novel role for an amino acid in the regulation of pluripotent cells in culture. AJP: Cell Physiology. 2010;298(5):C982-C92. doi: 10.1152/ajpcell.00498.2009 PMID: 20164384
    • (2010) AJP: Cell Physiology , vol.298 , Issue.5 , pp. C982-C92
    • Washington, J.M.1    Rathjen, J.2    Felquer, F.3    Lonic, A.4    Bettess, M.D.5    Hamra, N.6
  • 50
    • 84886089856 scopus 로고    scopus 로고
    • L-proline induces a mesenchymal-like invasive program in embryonic stem cells by remodeling H3K9 and H3K36 methylation
    • PMID: 24319666
    • Comes S, Gagliardi M, Laprano N, Fico A, Cimmino A, Palamidessi A, et al. L-Proline Induces a Mesenchymal-like Invasive Program in Embryonic Stem Cells by Remodeling H3K9 and H3K36 Methylation. Stem cell reports. 2013;1(4):307-21. doi: 10.1016/j.stemcr.2013.09.001 PMID: 24319666
    • (2013) Stem Cell Reports , vol.1 , Issue.4 , pp. 307-321
    • Comes, S.1    Gagliardi, M.2    Laprano, N.3    Fico, A.4    Cimmino, A.5    Palamidessi, A.6
  • 51
    • 84885591157 scopus 로고    scopus 로고
    • Exogenous polyamines promote osteogenic differentiation by reciprocally regulating osteogenic and adipogenic gene expression
    • PMID: 23794266
    • Lee M J, Chen Y, Huang YP, Hsu YC, Chiang LH, Chen TY, et al. Exogenous polyamines promote osteogenic differentiation by reciprocally regulating osteogenic and adipogenic gene expression. Journal of cellular biochemistry. 2013;114(12):2718-28. doi: 10.1002/jcb.24620 PMID: 23794266
    • (2013) Journal of Cellular Biochemistry , vol.114 , Issue.12 , pp. 2718-2728
    • Lee, M.J.1    Chen, Y.2    Huang, Y.P.3    Hsu, Y.C.4    Chiang, L.H.5    Chen, T.Y.6
  • 52
    • 0021267038 scopus 로고
    • Effects of polyamine depletion on proliferation and differentiation of murine erythroleukemia cells
    • PMID: 6423275
    • Sugiura M, Shafman T, Kufe D. Effects of polyamine depletion on proliferation and differentiation of murine erythroleukemia cells. Cancer research. 1984;44(4):1440-4. PMID: 6423275
    • (1984) Cancer Research , vol.44 , Issue.4 , pp. 1440-1444
    • Sugiura, M.1    Shafman, T.2    Kufe, D.3
  • 53
    • 18244411349 scopus 로고
    • Role of polyamines in differentiation of 3T3-L1 fibroblasts into adipocytes
    • Erwin BG, Bethell DR, Pegg AE. Role of polyamines in differentiation of 3T3-L1 fibroblasts into adipocytes. The American journal of physiology. 1984;246(3 Pt 1):C293-300.
    • (1984) The American Journal of Physiology , vol.246 , Issue.3 , pp. C293-C300
    • Erwin, B.G.1    Bethell, D.R.2    Pegg, A.E.3
  • 54
    • 0021219985 scopus 로고
    • The role of polyamines in somatomedin-stimulated differentiation of L6 myoblasts
    • PMID: 6430921
    • Ewton DZ, Erwin BG, Pegg AE, Florini JR. The role of polyamines in somatomedin-stimulated differentiation of L6 myoblasts. Journal of cellular physiology. 1984;120(3):263-70. doi: 10.1002/jcp. 1041200302 PMID: 6430921
    • (1984) Journal of Cellular Physiology , vol.120 , Issue.3 , pp. 263-270
    • Ewton, D.Z.1    Erwin, B.G.2    Pegg, A.E.3    Florini, J.R.4
  • 55
    • 84880061760 scopus 로고    scopus 로고
    • Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32with HuRand PP2A
    • PMID: 23672317
    • Hyvonen MT, Koponen T, Weisell J, Pietila M, Khomutov AR, Vepsalainen J, et al. Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32with HuRand PP2A. The Biochemical journal. 2013;453(3):467-74. doi: 10.1042/BJ20130263 PMID: 23672317
    • (2013) The Biochemical Journal , vol.453 , Issue.3 , pp. 467-474
    • Hyvonen, M.T.1    Koponen, T.2    Weisell, J.3    Pietila, M.4    Khomutov, A.R.5    Vepsalainen, J.6
  • 57
    • 84867487610 scopus 로고    scopus 로고
    • Induced pluripotent stem cells show metabolomic differences to embryonic stem cells in polyunsaturated phosphatidylcholines and primary metabolism
    • PMID: 23077522
    • Meissen JK, Yuen BTK, Kind T, Riggs JW, Barupal DK, Knoepfler PS, et al. Induced Pluripotent Stem Cells Show Metabolomic Differences to Embryonic Stem Cells in Polyunsaturated Phosphatidylcholines and Primary Metabolism. PLoSONE. 2012;7(10):e46770. doi: 10.1371/journal.pone.0046770. s005 PMID: 23077522
    • (2012) PLoSONE , vol.7 , Issue.10 , pp. e46770
    • Meissen, J.K.1    Yuen, B.T.K.2    Kind, T.3    Riggs, J.W.4    Barupal, D.K.5    Knoepfler, P.S.6
  • 58
    • 84907022547 scopus 로고    scopus 로고
    • Metabostemness: A new cancer hallmark
    • PMID: 25325014
    • Menendez JA, Alarcon T. Metabostemness: a new cancer hallmark. Frontiers in oncology. 2014;4:262. doi: 10.3389/fonc.2014.00262 PMID: 25325014
    • (2014) Frontiers in Oncology , vol.4 , pp. 262
    • Menendez, J.A.1    Alarcon, T.2
  • 59
    • 84908170488 scopus 로고    scopus 로고
    • Tracking down the origin of cancer: Metabolic reprogramming as a driver of stemness and tumorigenesis
    • PMID: 25404151
    • Sebastian C. Tracking down the origin of cancer: metabolic reprogramming as a driver of stemness and tumorigenesis. Critical reviews in oncogenesis. 2014;19(5):363-82. PMID: 25404151
    • (2014) Critical Reviews in Oncogenesis , vol.19 , Issue.5 , pp. 363-382
    • Sebastian, C.1
  • 60
    • 33845314350 scopus 로고    scopus 로고
    • Massspectrometry-basedmetabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors
    • PMID: 17108116
    • Denkert C, Budczies J, Kind T, Weichert W, Tablack P, Sehouli J, et al. Massspectrometry-basedmetabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors. Cancer Res. 2006;66(22):10795-804. doi: 10.1158/0008-5472.can-06-0755 PMID: 17108116
    • (2006) Cancer Res. , vol.66 , Issue.22 , pp. 10795-10804
    • Denkert, C.1    Budczies, J.2    Kind, T.3    Weichert, W.4    Tablack, P.5    Sehouli, J.6
  • 61
    • 84887444816 scopus 로고    scopus 로고
    • Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells
    • PMID: 24157871
    • Tedeschi PM, Markert EK, Gounder M, Lin H, Dvorzhinski D, Dolfi SC, et al. Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells. Cell Death Dis. 2013;4:e877. doi: 10.1038/cddis.2013.393 PMID: 24157871
    • (2013) Cell Death Dis. , vol.4 , pp. e877
    • Tedeschi, P.M.1    Markert, E.K.2    Gounder, M.3    Lin, H.4    Dvorzhinski, D.5    Dolfi, S.C.6
  • 62
    • 79958795339 scopus 로고    scopus 로고
    • Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2alpha accumulation and promotes migration and invasion
    • PMID: 21695080
    • Sudarshan S, Shanmugasundaram K, Naylor SL, Lin S, Livi CB, O'Neill CF, et al. Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2alpha accumulation and promotes migration and invasion. PLoSOne. 2011;6(6):e21037. doi: 10.1371/journal.pone.0021037 PMID: 21695080
    • (2011) PLoSOne , vol.6 , Issue.6 , pp. e21037
    • Sudarshan, S.1    Shanmugasundaram, K.2    Naylor, S.L.3    Lin, S.4    Livi, C.B.5    O'Neill, C.F.6
  • 63
    • 75149148563 scopus 로고    scopus 로고
    • Q's next: The diverse functions of glutamine in metabolism, cell biology and cancer
    • PMID: 19881548
    • De Berardinis RJ, Cheng T. Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer. Oncogene. 2010;29(3):313-24. doi: 10.1038/onc.2009.358 PMID: 19881548
    • (2010) Oncogene. , vol.29 , Issue.3 , pp. 313-324
    • De Berardinis, R.J.1    Cheng, T.2
  • 64
    • 77649219639 scopus 로고    scopus 로고
    • The origin and pathogenesis of epithelial ovarian cancer: A proposed unifying theory
    • PMID: 20154587
    • Kurman RJ, Shih Ie M. The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory. The American journal of surgical pathology. 2010;34(3):433-43. doi: 10.1097/PAS. 0b013e3181cf3d79 PMID: 20154587
    • (2010) The American Journal of Surgical Pathology , vol.34 , Issue.3 , pp. 433-443
    • Kurman, R.J.1    Shih Ie, M.2
  • 65
    • 84879674095 scopus 로고    scopus 로고
    • Precursors and pathogenesis of ovarian carcinoma
    • PMID: 23478230
    • Lim D, Oliva E. Precursors and pathogenesis of ovarian carcinoma. Pathology. 2013;45(3):229-42. doi: 10.1097/PAT.0b013e32835f2264 PMID: 23478230
    • (2013) Pathology , vol.45 , Issue.3 , pp. 229-242
    • Lim, D.1    Oliva, E.2


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