메뉴 건너뛰기




Volumn 9, Issue 4, 2015, Pages 1759-

Chemoresistance is associated with beclin-1 and PTEN expression in epithelial ovarian cancers

Author keywords

Autophagy; Beclin 1; Ovarian cancer; Phosphatase and tensin homolog; Platinum; Resistant

Indexed keywords

BECLIN 1; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

EID: 84923197169     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2015.2950     Document Type: Article
Times cited : (29)

References (31)
  • 2
    • 15544369937 scopus 로고    scopus 로고
    • Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line
    • Lee S, Choi EJ, Jin C and Kim DH: Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line. Gynecol Oncol 97: 26-34, 2005.
    • (2005) Gynecol Oncol , vol.97 , pp. 26-34
    • Lee, S.1    Choi, E.J.2    Jin, C.3    Kim, D.H.4
  • 3
    • 33745192802 scopus 로고    scopus 로고
    • Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
    • Hara T, Nakamura K, Matsui M, et al: Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441: 885-889, 2006.
    • (2006) Nature , vol.441 , pp. 885-889
    • Hara, T.1    Nakamura, K.2    Matsui, M.3
  • 4
    • 78049460392 scopus 로고    scopus 로고
    • Reduced expression of LC3B-II and Beclin 1 in glioblastoma multiforme indicates a down-regulated autophagic capacity that relates to the progression of astrocytic tumors
    • Huang X, Bai HM, Chen I, Li B and Lu YC: Reduced expression of LC3B-II and Beclin 1 in glioblastoma multiforme indicates a down-regulated autophagic capacity that relates to the progression of astrocytic tumors. J Clin Neurosci 17: 1515-1519, 2010.
    • (2010) J Clin Neurosci , vol.17 , pp. 1515-1519
    • Huang, X.1    Bai, H.M.2    Chen, I.3    Li, B.4    Lu, Y.C.5
  • 5
    • 84869124927 scopus 로고    scopus 로고
    • Cell biology. Promoting tumorigenesis by suppressing autophagy
    • Koren I and Kimchi A: Cell biology. Promoting tumorigenesis by suppressing autophagy. Science 338: 889-890, 2012.
    • (2012) Science , vol.338 , pp. 889-890
    • Koren, I.1    Kimchi, A.2
  • 6
    • 84875738196 scopus 로고    scopus 로고
    • Decreased expression of Beclin 1 correlates closely with Bcl-xL expression and poor prognosis of ovarian carcinoma
    • Lin HX, Qiu HJ, Zeng F, et al: Decreased expression of Beclin 1 correlates closely with Bcl-xL expression and poor prognosis of ovarian carcinoma. PLoS One 8: e60516, 2013.
    • (2013) Plos One , vol.8
    • Lin, H.X.1    Qiu, H.J.2    Zeng, F.3
  • 7
    • 84885435544 scopus 로고    scopus 로고
    • The significance of expression of autophagy-related gene Beclin, Bcl-2, and Bax in breast cancer tissues
    • Yao Q, Chen J, Lv Y, et al: The significance of expression of autophagy-related gene Beclin, Bcl-2, and Bax in breast cancer tissues. Tumour Biol 32: 1163-1171, 2011.
    • (2011) Tumour Biol , vol.32 , pp. 1163-1171
    • Yao, Q.1    Chen, J.2    Lv, Y.3
  • 8
    • 84873030827 scopus 로고    scopus 로고
    • Expression and significance of microsomal prostaglandin synthase-1 (MPGES-1) and Beclin-1 in the development of prostate cancer
    • Xu LW, Qian M, Jia RP, et al: Expression and significance of microsomal prostaglandin synthase-1 (mPGES-1) and Beclin-1 in the development of prostate cancer. Asian Pac J Cancer Prev 13: 1639-1644, 2012.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 1639-1644
    • Xu, L.W.1    Qian, M.2    Jia, R.P.3
  • 9
    • 77953708091 scopus 로고    scopus 로고
    • Elevated Beclin 1 expression is correlated with HIF-1alpha in predicting poor prognosis of nasopharyngeal carcinoma
    • Wan XB, Fan XJ, Chen MY, et al: Elevated Beclin 1 expression is correlated with HIF-1alpha in predicting poor prognosis of nasopharyngeal carcinoma. Autophagy 6: 395-404, 2010.
    • (2010) Autophagy , vol.6 , pp. 395-404
    • Wan, X.B.1    Fan, X.J.2    Chen, M.Y.3
  • 10
    • 0345166111 scopus 로고    scopus 로고
    • Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
    • Yue Z, Jin S, Yang C, Levine AJ and Heintz N: Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA 100: 15077-15082, 2003.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15077-15082
    • Yue, Z.1    Jin, S.2    Yang, C.3    Levine, A.J.4    Heintz, N.5
  • 11
    • 64049094855 scopus 로고    scopus 로고
    • Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium
    • Pecorelli S: Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gyneeol Obstet 105: 103-111, 2009.
    • (2009) Int J Gyneeol Obstet , vol.105 , pp. 103-111
    • Pecorelli, S.1
  • 13
    • 0031001041 scopus 로고    scopus 로고
    • TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta
    • Li DM and Sun H: TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta. Cancer Res 57: 2124-2129, 1997.
    • (1997) Cancer Res , vol.57 , pp. 2124-2129
    • Li, D.M.1    Sun, H.2
  • 14
    • 0031001041 scopus 로고    scopus 로고
    • TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta
    • Li DM and Sun H: TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta. Cancer Res 57: 2124-2129, 1997.
    • (1997) Cancer Res , vol.57 , pp. 2124-2129
    • Li, D.M.1    Sun, H.2
  • 15
    • 84868491254 scopus 로고    scopus 로고
    • Expression of miRNAs and PTEN in endometrial specimens ranging from histologically normal to hyperplasia and endometrial adenocarcinoma
    • Lee H, Choi HJ, Kang CS, Lee HJ, Lee WS and Park CS: Expression of miRNAs and PTEN in endometrial specimens ranging from histologically normal to hyperplasia and endometrial adenocarcinoma. Mod Pathol 25: 1508-1515, 2012.
    • (2012) Mod Pathol , vol.25 , pp. 1508-1515
    • Lee, H.1    Choi, H.J.2    Kang, C.S.3    Lee, H.J.4    Lee, W.S.5    Park, C.S.6
  • 18
    • 0037439234 scopus 로고    scopus 로고
    • PTEN encoding product: A marker for tumorigenesis and progression of gastric carcinoma
    • Yang L, Kuang LG, Zheng HC, et al: PTEN encoding product: a marker for tumorigenesis and progression of gastric carcinoma. World J Gastroenterol 9: 35-39, 2003.
    • (2003) World J Gastroenterol , vol.9 , pp. 35-39
    • Yang, L.1    Kuang, L.G.2    Zheng, H.C.3
  • 19
    • 80055097355 scopus 로고    scopus 로고
    • Selective gene expression profiling of mTOR-associated tumor suppressor and oncogenes in ovarian cancer
    • Laudański P, Kowalczuk O, Klasa-Mazurkiewicz D, et al: Selective gene expression profiling of mTOR-associated tumor suppressor and oncogenes in ovarian cancer. Folia Histochem Cytobiol 49: 317-324, 2011.
    • (2011) Folia Histochem Cytobiol , vol.49 , pp. 317-324
    • Laudański, P.1    Kowalczuk, O.2    Klasa-Mazurkiewicz, D.3
  • 20
    • 83055165668 scopus 로고    scopus 로고
    • Prognostic impact of concomitant p53 and PTEN on outcome in early stage (FIGO I-II) epithelial ovarian cancer
    • Skírnisdóttir I and Seidal T: Prognostic impact of concomitant p53 and PTEN on outcome in early stage (FIGO I-II) epithelial ovarian cancer. Int J Gynecol Cancer 21: 1024-1031, 2011.
    • (2011) Int J Gynecol Cancer , vol.21 , pp. 1024-1031
    • Skírnisdóttir, I.1    Seidal, T.2
  • 21
    • 84863882834 scopus 로고    scopus 로고
    • New insights on the pathogenesis of ovarian carcinoma: Molecular basis and clinical implications
    • Gadducci A, Guerrieri ME and Genazzani AR: New insights on the pathogenesis of ovarian carcinoma: molecular basis and clinical implications. Gynecol Endocrinol 28: 582-586, 2012.
    • (2012) Gynecol Endocrinol , vol.28 , pp. 582-586
    • Gadducci, A.1    Guerrieri, M.E.2    Genazzani, A.R.3
  • 22
    • 35348930988 scopus 로고    scopus 로고
    • EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expression
    • Selvendiran K, Tong L, Vishwanath S, et al: EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expression. J Biol Chem 282: 28609-28618, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 28609-28618
    • Selvendiran, K.1    Tong, L.2    Vishwanath, S.3
  • 24
    • 33745987641 scopus 로고    scopus 로고
    • Over-expression of PTEN sensitizes human ovarian cancer cells to cisplatin-induced apoptosis in a p53-dependent manner
    • Yan X, Fraser M, Qiu Q and Tsang BK: Over-expression of PTEN sensitizes human ovarian cancer cells to cisplatin-induced apoptosis in a p53-dependent manner. Gynecol Oncol 102: 348-355, 2006.
    • (2006) Gynecol Oncol , vol.102 , pp. 348-355
    • Yan, X.1    Fraser, M.2    Qiu, Q.3    Tsang, B.K.4
  • 25
    • 47249094223 scopus 로고    scopus 로고
    • Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
    • Scarlatti F, Maffei R, Beau I, Codogno P and Ghidoni R: Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death Differ 15: 1318-1329, 2008.
    • (2008) Cell Death Differ , vol.15 , pp. 1318-1329
    • Scarlatti, F.1    Maffei, R.2    Beau, I.3    Codogno, P.4    Ghidoni, R.5
  • 26
    • 77953358737 scopus 로고    scopus 로고
    • Over-expression of the Beclin1 gene upregulates chemosensitivity to anti-cancer drugs by enhancing therapy-induced apoptosis in cervix squamous carcinoma CaSki cells
    • Sun Y, Liu JH, Jin L, et al: Over-expression of the Beclin1 gene upregulates chemosensitivity to anti-cancer drugs by enhancing therapy-induced apoptosis in cervix squamous carcinoma CaSki cells. Cancer Lett 294: 204-210, 2010.
    • (2010) Cancer Lett , vol.294 , pp. 204-210
    • Sun, Y.1    Liu, J.H.2    Jin, L.3
  • 27
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B and Kroemer G: Autophagy in the pathogenesis of disease. Cell 132: 27-42, 2008.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 28
    • 80053634368 scopus 로고    scopus 로고
    • The dynamic nature of autophagy in cancer
    • Kimmelman AC: The dynamic nature of autophagy in cancer. Genes Dev 25: 1999-2010, 2011.
    • (2011) Genes Dev , vol.25 , pp. 1999-2010
    • Kimmelman, A.C.1
  • 29
    • 37549063395 scopus 로고    scopus 로고
    • Expression of beclin-l, an autophagy-related protein, in gastric and colorectal cancers
    • Ahn CH, Jeong EG, Lee JW et al: Expression of beclin-l, an autophagy-related protein, in gastric and colorectal cancers. APMIS 115: 1344-1349, 2007.
    • (2007) APMIS , vol.115 , pp. 1344-1349
    • Ahn, C.H.1    Jeong, E.G.2    Lee, J.W.3
  • 30
    • 58949098335 scopus 로고    scopus 로고
    • Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression
    • Tang H, Da L, Mao Y, et al: Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression. Hepatology 49: 60-71, 2009.
    • (2009) Hepatology , vol.49 , pp. 60-71
    • Tang, H.1    Da, L.2    Mao, Y.3
  • 31
    • 0346998038 scopus 로고    scopus 로고
    • Defective autophagy leads to cancer
    • Edinger AL and Thompson CB: Defective autophagy leads to cancer. Cancer Cell 4: 422-424, 2003.
    • (2003) Cancer Cell , vol.4 , pp. 422-424
    • Edinger, A.L.1    Thompson, C.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.