-
1
-
-
33846457870
-
Cancer statistics, 2007
-
Jemal A, Siegel R, Ward E, Murray T, Xu J, et al. (2007) Cancer statistics, 2007. CA Cancer J Clin 57: 43-66.
-
(2007)
CA Cancer J Clin
, vol.57
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
-
2
-
-
0031776311
-
Genetics and ovarian carcinoma
-
Lynch HT, Casey MJ, Lynch J, White TE, Godwin AK, (1998) Genetics and ovarian carcinoma. Semin Oncol 25: 265-280.
-
(1998)
Semin Oncol
, vol.25
, pp. 265-280
-
-
Lynch, H.T.1
Casey, M.J.2
Lynch, J.3
White, T.E.4
Godwin, A.K.5
-
3
-
-
0028084765
-
FIGO stage, histology, histologic grade, age and race as prognostic factors in determining survival for cancers of the female gynecological system: an analysis of 1973-87 SEER cases of cancers of the endometrium, cervix, ovary, vulva, and vagina
-
Kosary CL, (1994) FIGO stage, histology, histologic grade, age and race as prognostic factors in determining survival for cancers of the female gynecological system: an analysis of 1973-87 SEER cases of cancers of the endometrium, cervix, ovary, vulva, and vagina. Semin Surg Oncol 10: 31-46.
-
(1994)
Semin Surg Oncol
, vol.10
, pp. 31-46
-
-
Kosary, C.L.1
-
4
-
-
0036365026
-
Current diagnosis and treatment modalities for ovarian cancer
-
Schwartz PE, (2002) Current diagnosis and treatment modalities for ovarian cancer. Cancer Treat Res 107: 99-118.
-
(2002)
Cancer Treat Res
, vol.107
, pp. 99-118
-
-
Schwartz, P.E.1
-
5
-
-
39749171410
-
Early events in the pathogenesis of epithelial ovarian cancer
-
Landen CN Jr, Birrer MJ, Sood AK, (2008) Early events in the pathogenesis of epithelial ovarian cancer. J Clin Oncol 26: 995-1005.
-
(2008)
J Clin Oncol
, vol.26
, pp. 995-1005
-
-
Landen Jr, C.N.1
Birrer, M.J.2
Sood, A.K.3
-
6
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, et al. (1999) Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402: 672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
-
7
-
-
0001488499
-
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
-
Liang XH, Kleeman LK, Jiang HH, Gordon G, Goldman JE, et al. (1998) Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol 72: 8586-8596.
-
(1998)
J Virol
, vol.72
, pp. 8586-8596
-
-
Liang, X.H.1
Kleeman, L.K.2
Jiang, H.H.3
Gordon, G.4
Goldman, J.E.5
-
8
-
-
59149090850
-
Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy
-
Pattingre S, Bauvy C, Carpentier S, Levade T, Levine B, et al. (2009) Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy. J Biol Chem 284: 2719-2728.
-
(2009)
J Biol Chem
, vol.284
, pp. 2719-2728
-
-
Pattingre, S.1
Bauvy, C.2
Carpentier, S.3
Levade, T.4
Levine, B.5
-
9
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, et al. (2005) Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122: 927-939.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Liang, X.H.5
-
10
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
-
Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, et al. (2004) Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 6: 1221-1228.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1221-1228
-
-
Shimizu, S.1
Kanaseki, T.2
Mizushima, N.3
Mizuta, T.4
Arakawa-Kobayashi, S.5
-
11
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, et al. (2008) Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem 283: 10892-10903.
-
(2008)
J Biol Chem
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
-
12
-
-
38749136302
-
Regulation of macroautophagy by mTOR and Beclin 1 complexes
-
Pattingre S, Espert L, Biard-Piechaczyk M, Codogno P, (2008) Regulation of macroautophagy by mTOR and Beclin 1 complexes. Biochimie 90: 313-323.
-
(2008)
Biochimie
, vol.90
, pp. 313-323
-
-
Pattingre, S.1
Espert, L.2
Biard-Piechaczyk, M.3
Codogno, P.4
-
13
-
-
60549089824
-
Overexpression of EIF-5A2 is an independent predictor of outcome in patients of urothelial carcinoma of the bladder treated with radical cystectomy
-
Chen W, Luo JH, Hua WF, Zhou FJ, Lin MC, et al. (2009) Overexpression of EIF-5A2 is an independent predictor of outcome in patients of urothelial carcinoma of the bladder treated with radical cystectomy. Cancer Epidemiol Biomarkers Prev 18: 400-408.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 400-408
-
-
Chen, W.1
Luo, J.H.2
Hua, W.F.3
Zhou, F.J.4
Lin, M.C.5
-
14
-
-
34347344990
-
Ambra1 regulates autophagy and development of the nervous system
-
Fimia GM, Stoykova A, Romagnoli A, Giunta L, Di Bartolomeo S, et al. (2007) Ambra1 regulates autophagy and development of the nervous system. Nature 447: 1121-1125.
-
(2007)
Nature
, vol.447
, pp. 1121-1125
-
-
Fimia, G.M.1
Stoykova, A.2
Romagnoli, A.3
Giunta, L.4
Di Bartolomeo, S.5
-
15
-
-
34848899280
-
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
-
Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, et al. (2007) Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nat Cell Biol 9: 1142-1151.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1142-1151
-
-
Takahashi, Y.1
Coppola, D.2
Matsushita, N.3
Cualing, H.D.4
Sun, M.5
-
16
-
-
39049194057
-
The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
-
Furuya N, Yu J, Byfield M, Pattingre S, Levine B, (2005) The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy 1: 46-52.
-
(2005)
Autophagy
, vol.1
, pp. 46-52
-
-
Furuya, N.1
Yu, J.2
Byfield, M.3
Pattingre, S.4
Levine, B.5
-
17
-
-
59249089394
-
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
-
Itakura E, Kishi C, Inoue K, Mizushima N, (2008) Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell 19: 5360-5372.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 5360-5372
-
-
Itakura, E.1
Kishi, C.2
Inoue, K.3
Mizushima, N.4
-
18
-
-
34248998801
-
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
-
Maiuri MC, Le Toumelin G, Criollo A, Rain JC, Gautier F, et al. (2007) Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J 26: 2527-2539.
-
(2007)
EMBO J
, vol.26
, pp. 2527-2539
-
-
Maiuri, M.C.1
Le Toumelin, G.2
Criollo, A.3
Rain, J.C.4
Gautier, F.5
-
19
-
-
57649184088
-
Control of autophagy by oncogenes and tumor suppressor genes
-
Maiuri MC, Tasdemir E, Criollo A, Morselli E, Vicencio JM, et al. (2009) Control of autophagy by oncogenes and tumor suppressor genes. Cell Death Differ 16: 87-93.
-
(2009)
Cell Death Differ
, vol.16
, pp. 87-93
-
-
Maiuri, M.C.1
Tasdemir, E.2
Criollo, A.3
Morselli, E.4
Vicencio, J.M.5
-
20
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu X, Yu J, Bhagat G, Furuya N, Hibshoosh H, et al. (2003) Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest 112: 1809-1820.
-
(2003)
J Clin Invest
, vol.112
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Hibshoosh, H.5
-
21
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N, (2003) Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A 100: 15077-15082.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
22
-
-
34047271129
-
Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours
-
Miracco C, Cosci E, Oliveri G, Luzi P, Pacenti L, et al. (2007) Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours. Int J Oncol 30: 429-436.
-
(2007)
Int J Oncol
, vol.30
, pp. 429-436
-
-
Miracco, C.1
Cosci, E.2
Oliveri, G.3
Luzi, P.4
Pacenti, L.5
-
23
-
-
65249135974
-
Prognostic significance of Beclin 1-dependent apoptotic activity in hepatocellular carcinoma
-
Shi YH, Ding ZB, Zhou J, Qiu SJ, Fan J, (2009) Prognostic significance of Beclin 1-dependent apoptotic activity in hepatocellular carcinoma. Autophagy 5: 380-382.
-
(2009)
Autophagy
, vol.5
, pp. 380-382
-
-
Shi, Y.H.1
Ding, Z.B.2
Zhou, J.3
Qiu, S.J.4
Fan, J.5
-
24
-
-
37549063395
-
Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers
-
Ahn CH, Jeong EG, Lee JW, Kim MS, Kim SH, et al. (2007) Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers. APMIS 115: 1344-1349.
-
(2007)
APMIS
, vol.115
, pp. 1344-1349
-
-
Ahn, C.H.1
Jeong, E.G.2
Lee, J.W.3
Kim, M.S.4
Kim, S.H.5
-
25
-
-
77953708091
-
Elevated Beclin 1 expression is correlated with HIF-1alpha in predicting poor prognosis of nasopharyngeal carcinoma
-
Wan XB, Fan XJ, Chen MY, Xiang J, Huang PY, et al. (2010) Elevated Beclin 1 expression is correlated with HIF-1alpha in predicting poor prognosis of nasopharyngeal carcinoma. Autophagy 6: 395-404.
-
(2010)
Autophagy
, vol.6
, pp. 395-404
-
-
Wan, X.B.1
Fan, X.J.2
Chen, M.Y.3
Xiang, J.4
Huang, P.Y.5
-
26
-
-
77955899223
-
Beclin 1 expression: predictor of prognosis in patients with extranodal natural killer T-cell lymphoma, nasal type
-
Huang JJ, Li HR, Huang Y, Jiang WQ, Xu RH, et al. (2010) Beclin 1 expression: predictor of prognosis in patients with extranodal natural killer T-cell lymphoma, nasal type. Autophagy 6: 777-783.
-
(2010)
Autophagy
, vol.6
, pp. 777-783
-
-
Huang, J.J.1
Li, H.R.2
Huang, Y.3
Jiang, W.Q.4
Xu, R.H.5
-
27
-
-
58149084586
-
Decreased expression of autophagy-related proteins in malignant epithelial ovarian cancer
-
Shen Y, Li DD, Wang LL, Deng R, Zhu XF, (2008) Decreased expression of autophagy-related proteins in malignant epithelial ovarian cancer. Autophagy 4: 1067-1068.
-
(2008)
Autophagy
, vol.4
, pp. 1067-1068
-
-
Shen, Y.1
Li, D.D.2
Wang, L.L.3
Deng, R.4
Zhu, X.F.5
-
28
-
-
8444244786
-
X-tile: a new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization
-
Camp RL, Dolled-Filhart M, Rimm DL, (2004) X-tile: a new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization. Clin Cancer Res 10: 7252-7259.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7252-7259
-
-
Camp, R.L.1
Dolled-Filhart, M.2
Rimm, D.L.3
-
29
-
-
79954551933
-
Expressions of the gamma2 chain of laminin-5 and secreted protein acidic and rich in cysteine in esophageal squamous cell carcinoma and their relation to prognosis
-
Xue LY, Zou SM, Zheng S, Liu XY, Wen P, et al. (2011) Expressions of the gamma2 chain of laminin-5 and secreted protein acidic and rich in cysteine in esophageal squamous cell carcinoma and their relation to prognosis. Chin J Cancer 30: 69-78.
-
(2011)
Chin J Cancer
, vol.30
, pp. 69-78
-
-
Xue, L.Y.1
Zou, S.M.2
Zheng, S.3
Liu, X.Y.4
Wen, P.5
-
30
-
-
30644472260
-
Expression of cytoplasmic and nuclear Survivin in primary and secondary human glioblastoma
-
Xie D, Zeng YX, Wang HJ, Wen JM, Tao Y, et al. (2006) Expression of cytoplasmic and nuclear Survivin in primary and secondary human glioblastoma. Br J Cancer 94: 108-114.
-
(2006)
Br J Cancer
, vol.94
, pp. 108-114
-
-
Xie, D.1
Zeng, Y.X.2
Wang, H.J.3
Wen, J.M.4
Tao, Y.5
-
31
-
-
84867509337
-
Expression of RRM1 and its association with resistancy to gemcitabine-based chemotherapy in advanced nasopharyngeal carcinoma
-
Zhao LP, Xue C, Zhang JW, Hu ZH, Zhao YY, et al. (2012) Expression of RRM1 and its association with resistancy to gemcitabine-based chemotherapy in advanced nasopharyngeal carcinoma. Chin J Cancer 31: 476-483.
-
(2012)
Chin J Cancer
, vol.31
, pp. 476-483
-
-
Zhao, L.P.1
Xue, C.2
Zhang, J.W.3
Hu, Z.H.4
Zhao, Y.Y.5
-
32
-
-
68949212362
-
PIK3CA alterations in Middle Eastern ovarian cancers
-
Abubaker J, Bavi P, Al-Haqawi W, Jehan Z, Munkarah A, et al. (2009) PIK3CA alterations in Middle Eastern ovarian cancers. Mol Cancer 8: 51.
-
(2009)
Mol Cancer
, vol.8
, pp. 51
-
-
Abubaker, J.1
Bavi, P.2
Al-Haqawi, W.3
Jehan, Z.4
Munkarah, A.5
-
33
-
-
78651506355
-
High expression of H3K27me3 in human hepatocellular carcinomas correlates closely with vascular invasion and predicts patients worse prognosis
-
Cai MY, Hou JH, Rao HL, Luo RZ, Li M, et al. (2011) High expression of H3K27me3 in human hepatocellular carcinomas correlates closely with vascular invasion and predicts patients worse prognosis. Mol Med 1-2: 12-20.
-
(2011)
Mol Med
, vol.1-2
, pp. 12-20
-
-
Cai, M.Y.1
Hou, J.H.2
Rao, H.L.3
Luo, R.Z.4
Li, M.5
-
34
-
-
0017277826
-
Monte Carlo principles and applications
-
Raeside DE, (1976) Monte Carlo principles and applications. Phys Med Biol 21: 181-197.
-
(1976)
Phys Med Biol
, vol.21
, pp. 181-197
-
-
Raeside, D.E.1
-
35
-
-
34147193472
-
Cell biology: autophagy and cancer
-
Levine B, (2007) Cell biology: autophagy and cancer. Nature 446: 745-747.
-
(2007)
Nature
, vol.446
, pp. 745-747
-
-
Levine, B.1
-
37
-
-
56449107131
-
Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma
-
Ding ZB, Shi YH, Zhou J, Qiu SJ, Xu Y, et al. (2008) Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma. Cancer Res 68: 9167-9175.
-
(2008)
Cancer Res
, vol.68
, pp. 9167-9175
-
-
Ding, Z.B.1
Shi, Y.H.2
Zhou, J.3
Qiu, S.J.4
Xu, Y.5
-
38
-
-
70349641918
-
Beclin-1 expression is a predictor of clinical outcome in patients with esophageal squamous cell carcinoma and correlated to hypoxia-inducible factor (HIF)-1alpha expression
-
Chen Y, Lu Y, Lu C, Zhang L, (2009) Beclin-1 expression is a predictor of clinical outcome in patients with esophageal squamous cell carcinoma and correlated to hypoxia-inducible factor (HIF)-1alpha expression. Pathol Oncol Res 15: 487-493.
-
(2009)
Pathol Oncol Res
, vol.15
, pp. 487-493
-
-
Chen, Y.1
Lu, Y.2
Lu, C.3
Zhang, L.4
-
39
-
-
65249180744
-
The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers
-
Li BX, Li CY, Peng RQ, Wu XJ, Wang HY, et al. (2009) The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers. Autophagy 5: 303-306.
-
(2009)
Autophagy
, vol.5
, pp. 303-306
-
-
Li, B.X.1
Li, C.Y.2
Peng, R.Q.3
Wu, X.J.4
Wang, H.Y.5
-
40
-
-
70349649219
-
The prognostic role of Beclin 1 protein expression in high-grade gliomas
-
Pirtoli L, Cevenini G, Tini P, Vannini M, Oliveri G, et al. (2009) The prognostic role of Beclin 1 protein expression in high-grade gliomas. Autophagy 5: 930-936.
-
(2009)
Autophagy
, vol.5
, pp. 930-936
-
-
Pirtoli, L.1
Cevenini, G.2
Tini, P.3
Vannini, M.4
Oliveri, G.5
-
41
-
-
34249037565
-
Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein
-
Oberstein A, Jeffrey PD, Shi Y, (2007) Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. J Biol Chem 282: 13123-13132.
-
(2007)
J Biol Chem
, vol.282
, pp. 13123-13132
-
-
Oberstein, A.1
Jeffrey, P.D.2
Shi, Y.3
-
42
-
-
59149096565
-
ARF induces autophagy by virtue of interaction with Bcl-xl
-
Pimkina J, Humbey O, Zilfou JT, Jarnik M, Murphy ME, (2009) ARF induces autophagy by virtue of interaction with Bcl-xl. J Biol Chem 284: 2803-2810.
-
(2009)
J Biol Chem
, vol.284
, pp. 2803-2810
-
-
Pimkina, J.1
Humbey, O.2
Zilfou, J.T.3
Jarnik, M.4
Murphy, M.E.5
|