Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation

Nature Chemistry

Volumn 7, Issue 3, 2015, Pages 241-249

  Wichert, Moreno ^a   Krall, Nikolaus ^a   Decurtins, Willy ^a   Franzini, Raphael M ^a   Pretto, Francesca ^b   Schneider, Petra ^a   Neri, Dario ^a   Scheuermann, Jörg ^a  

^a ETH ZURICH   (Switzerland)

^b PHILOCHEM AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONATE DEHYDRATASE; DNA; HORSERADISH PEROXIDASE; LIGAND; MOLECULAR LIBRARY; OROSOMUCOID; STREPTAVIDIN;

ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DRUG DEVELOPMENT; MOLECULAR LIBRARY; MOUSE; NUCLEIC ACID HYBRIDIZATION; NUDE MOUSE; VALIDATION STUDY;

ANIMALS; CARBONIC ANHYDRASES; DNA; DRUG DISCOVERY; HORSERADISH PEROXIDASE; LIGANDS; MICE; MICE, INBRED BALB C; MICE, NUDE; NUCLEIC ACID HYBRIDIZATION; OROSOMUCOID; SMALL MOLECULE LIBRARIES; STREPTAVIDIN;

EID: 84923182115     PISSN: 17554330     EISSN: 17554349     Source Type: Journal    
DOI: 10.1038/nchem.2158     Document Type: Article

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