NADPH oxidase 4 is a critical mediator in Ataxia telangiectasia disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 7, 2015, Pages 2121-2126

  Weyemia, Urbain ^a   Redon, Christophe E ^a   Aziz, Towqir ^a   Choudhuri, Rohini ^a   Maeda, Daisuke ^a   Parekh, Palak R ^a   Bonner, Michael Y ^b   Arbiser, Jack L ^b   Bonner, William M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ataxia; DNA damage; Neurodegeneration; NOX4; ROS; Telangiectasia

Indexed keywords

ATM PROTEIN; ENZYME INHIBITOR; FULVENE 5; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; NOX4 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ADOLESCENT; ADULT; ARTICLE; ATAXIA TELANGIECTASIA; CANCER CONTROL; CANCER INCIDENCE; CONTROLLED STUDY; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERVENTION STUDY; MALE; MEDIATOR; MIDDLE AGED; MOUSE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; YOUNG ADULT; ANIMAL; DNA DAMAGE; ENZYMOLOGY; METABOLISM; PATHOLOGY;

MUS;

ADULT; ANIMALS; ATAXIA TELANGIECTASIA; DNA DAMAGE; DNA REPLICATION; FEMALE; HUMANS; MALE; MICE; MIDDLE AGED; NADPH OXIDASE; YOUNG ADULT;

EID: 84923164530     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1418139112     Document Type: Article

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