-
1
-
-
0037542854
-
Ras proteins: different signals from different locations
-
Hancock J.F. Ras proteins: different signals from different locations. Nat. Rev. Mol. Cell Biol. 2003, 4:373-384.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 373-384
-
-
Hancock, J.F.1
-
2
-
-
33644864788
-
Compartmentalized Ras/MAPK signaling
-
Mor A., Philips M.R. Compartmentalized Ras/MAPK signaling. Annu. Rev. Immunol. 2006, 24:771-800.
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 771-800
-
-
Mor, A.1
Philips, M.R.2
-
3
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward J. Targeting RAS signalling pathways in cancer therapy. Nat. Rev. Cancer 2003, 3:11-22.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
4
-
-
84861147473
-
A comprehensive survey of Ras mutations in cancer
-
Prior I.A., Lewis P.D., Mattos C. A comprehensive survey of Ras mutations in cancer. Cancer Res. 2012, 72:2457-2467.
-
(2012)
Cancer Res.
, vol.72
, pp. 2457-2467
-
-
Prior, I.A.1
Lewis, P.D.2
Mattos, C.3
-
5
-
-
84858796808
-
Ras trafficking, localization and compartmentalized signalling
-
Prior I.A., Hancock J.F. Ras trafficking, localization and compartmentalized signalling. Semin. Cell Dev. Biol. 2012, 23:145-153.
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 145-153
-
-
Prior, I.A.1
Hancock, J.F.2
-
6
-
-
0034998678
-
Compartmentalization of Ras proteins
-
Prior I.A., Hancock J.F. Compartmentalization of Ras proteins. J. Cell Sci. 2001, 114:1603-1608.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 1603-1608
-
-
Prior, I.A.1
Hancock, J.F.2
-
8
-
-
0037455589
-
Direct visualization of Ras proteins in spatially distinct cell surface microdomains
-
Prior I.A., Muncke C., Parton R.G., Hancock J.F. Direct visualization of Ras proteins in spatially distinct cell surface microdomains. J. Cell Biol. 2003, 160:165-170.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 165-170
-
-
Prior, I.A.1
Muncke, C.2
Parton, R.G.3
Hancock, J.F.4
-
9
-
-
27344456331
-
H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton
-
Plowman S.J., Muncke C., Parton R.G., Hancock J.F. H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:15500-15505.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 15500-15505
-
-
Plowman, S.J.1
Muncke, C.2
Parton, R.G.3
Hancock, J.F.4
-
10
-
-
84893839471
-
Signal Integration by Lipid-Mediated Spatial Cross Talk between Ras Nanoclusters
-
Zhou Y., Liang H., Rodkey T., Ariotti N., Parton R.G., Hancock J.F. Signal Integration by Lipid-Mediated Spatial Cross Talk between Ras Nanoclusters. Mol. Cell. Biol. 2014, 34:862-876.
-
(2014)
Mol. Cell. Biol.
, vol.34
, pp. 862-876
-
-
Zhou, Y.1
Liang, H.2
Rodkey, T.3
Ariotti, N.4
Parton, R.G.5
Hancock, J.F.6
-
11
-
-
75749150934
-
Ras membrane orientation and nanodomain localization generate isoform diversity
-
Abankwa D., Gorfe A.A., Inder K., Hancock J.F. Ras membrane orientation and nanodomain localization generate isoform diversity. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:1130-1135.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 1130-1135
-
-
Abankwa, D.1
Gorfe, A.A.2
Inder, K.3
Hancock, J.F.4
-
12
-
-
40949130399
-
A novel switch region regulates H-ras membrane orientation and signal output
-
Abankwa D., Hanzal-Bayer M., Ariotti N., Plowman S.J., Gorfe A.A., Parton R.G., McCammon J.A., Hancock J.F. A novel switch region regulates H-ras membrane orientation and signal output. EMBO J. 2008, 27:727-735.
-
(2008)
EMBO J.
, vol.27
, pp. 727-735
-
-
Abankwa, D.1
Hanzal-Bayer, M.2
Ariotti, N.3
Plowman, S.J.4
Gorfe, A.A.5
Parton, R.G.6
McCammon, J.A.7
Hancock, J.F.8
-
13
-
-
2442538177
-
Single-molecule imaging analysis of Ras activation in living cells
-
Murakoshi H., Iino R., Kobayashi T., Fujiwara T., Ohshima C., Yoshimura A., Kusumi A. Single-molecule imaging analysis of Ras activation in living cells. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:7317-7322.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 7317-7322
-
-
Murakoshi, H.1
Iino, R.2
Kobayashi, T.3
Fujiwara, T.4
Ohshima, C.5
Yoshimura, A.6
Kusumi, A.7
-
14
-
-
63449122293
-
Functional analysis of the leading malaria vaccine candidate AMA-1 reveals an essential role for the cytoplasmic domain in the invasion process
-
Treeck M., Zacherl S., Herrmann S., Cabrera A., Kono M., Struck N.S., Engelberg K., Haase S., Frischknecht F., Miura K., Spielmann T., Gilberger T.W. Functional analysis of the leading malaria vaccine candidate AMA-1 reveals an essential role for the cytoplasmic domain in the invasion process. PLoS Pathog. 2009, 5:e1000322.
-
(2009)
PLoS Pathog.
, vol.5
, pp. e1000322
-
-
Treeck, M.1
Zacherl, S.2
Herrmann, S.3
Cabrera, A.4
Kono, M.5
Struck, N.S.6
Engelberg, K.7
Haase, S.8
Frischknecht, F.9
Miura, K.10
Spielmann, T.11
Gilberger, T.W.12
-
15
-
-
77955213426
-
Mathematical modeling of K-Ras nanocluster formation on the plasma membrane
-
Tian T., Plowman S.J., Parton R.G., Kloog Y., Hancock J.F. Mathematical modeling of K-Ras nanocluster formation on the plasma membrane. Biophys. J. 2010, 99:534-543.
-
(2010)
Biophys. J.
, vol.99
, pp. 534-543
-
-
Tian, T.1
Plowman, S.J.2
Parton, R.G.3
Kloog, Y.4
Hancock, J.F.5
-
16
-
-
84861438588
-
Organization, dynamics, and segregation of Ras nanoclusters in membrane domains
-
Janosi L., Li Z., Hancock J.F., Gorfe A.A. Organization, dynamics, and segregation of Ras nanoclusters in membrane domains. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:8097-8102.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 8097-8102
-
-
Janosi, L.1
Li, Z.2
Hancock, J.F.3
Gorfe, A.A.4
-
17
-
-
84867030014
-
N-Ras forms dimers at POPC membranes
-
Guldenhaupt J., Rudack T., Bachler P., Mann D., Triola G., Waldmann H., Kotting C., Gerwert K. N-Ras forms dimers at POPC membranes. Biophys. J. 2012, 103:1585-1593.
-
(2012)
Biophys. J.
, vol.103
, pp. 1585-1593
-
-
Guldenhaupt, J.1
Rudack, T.2
Bachler, P.3
Mann, D.4
Triola, G.5
Waldmann, H.6
Kotting, C.7
Gerwert, K.8
-
18
-
-
84896840047
-
H-Ras forms dimers on membrane surfaces via a protein-protein interface
-
Lin W.C., Iversen L., Tu H.L., Rhodes C., Christensen S.M., Iwig J.S., Hansen S.D., Huang W.Y., Groves J.T. H-Ras forms dimers on membrane surfaces via a protein-protein interface. Proc. Natl. Acad. Sci. U. S. A. 2014, 111:2996-3001.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 2996-3001
-
-
Lin, W.C.1
Iversen, L.2
Tu, H.L.3
Rhodes, C.4
Christensen, S.M.5
Iwig, J.S.6
Hansen, S.D.7
Huang, W.Y.8
Groves, J.T.9
-
19
-
-
84887425345
-
Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling
-
Nan X., Collisson E.A., Lewis S., Huang J., Tamguney T.M., Liphardt J.T., McCormick F., Gray J.W., Chu S. Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:18519-18524.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 18519-18524
-
-
Nan, X.1
Collisson, E.A.2
Lewis, S.3
Huang, J.4
Tamguney, T.M.5
Liphardt, J.T.6
McCormick, F.7
Gray, J.W.8
Chu, S.9
-
20
-
-
29144528806
-
Ras signaling from plasma membrane and endomembrane microdomains
-
Plowman S.J., Hancock J.F. Ras signaling from plasma membrane and endomembrane microdomains. Biochim. Biophys. Acta 2005, 1746:274-283.
-
(2005)
Biochim. Biophys. Acta
, vol.1746
, pp. 274-283
-
-
Plowman, S.J.1
Hancock, J.F.2
-
21
-
-
46149107301
-
Electrostatic interactions positively regulate K-Ras nanocluster formation and function
-
Plowman S.J., Ariotti N., Goodall A., Parton R.G., Hancock J.F. Electrostatic interactions positively regulate K-Ras nanocluster formation and function. Mol. Cell. Biol. 2008, 28:4377-4385.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4377-4385
-
-
Plowman, S.J.1
Ariotti, N.2
Goodall, A.3
Parton, R.G.4
Hancock, J.F.5
-
22
-
-
35048822834
-
H-ras protein in a bilayer: interaction and structure perturbation
-
Gorfe A.A., Babakhani A., McCammon J.A. H-ras protein in a bilayer: interaction and structure perturbation. J. Am. Chem. Soc. 2007, 129:12280-12286.
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 12280-12286
-
-
Gorfe, A.A.1
Babakhani, A.2
McCammon, J.A.3
-
23
-
-
34547561587
-
Plasma membrane nanoswitches generate high-fidelity Ras signal transduction
-
Tian T., Harding A., Inder K., Plowman S., Parton R.G., Hancock J.F. Plasma membrane nanoswitches generate high-fidelity Ras signal transduction. Nat. Cell Biol. 2007, 9:905-914.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 905-914
-
-
Tian, T.1
Harding, A.2
Inder, K.3
Plowman, S.4
Parton, R.G.5
Hancock, J.F.6
-
24
-
-
48449092211
-
Using plasma membrane nanoclusters to build better signaling circuits
-
Harding A.S., Hancock J.F. Using plasma membrane nanoclusters to build better signaling circuits. Trends Cell Biol. 2008, 18:364-371.
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 364-371
-
-
Harding, A.S.1
Hancock, J.F.2
-
25
-
-
34547200183
-
Dissection of the components for PIP2 activation and thermosensation in TRP channels
-
Brauchi S., Orta G., Mascayano C., Salazar M., Raddatz N., Urbina H., Rosenmann E., Gonzalez-Nilo F., Latorre R. Dissection of the components for PIP2 activation and thermosensation in TRP channels. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:10246-10251.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 10246-10251
-
-
Brauchi, S.1
Orta, G.2
Mascayano, C.3
Salazar, M.4
Raddatz, N.5
Urbina, H.6
Rosenmann, E.7
Gonzalez-Nilo, F.8
Latorre, R.9
-
27
-
-
0025013547
-
A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane
-
Hancock J.F., Paterson H., Marshall C.J. A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane. Cell 1990, 63:133-139.
-
(1990)
Cell
, vol.63
, pp. 133-139
-
-
Hancock, J.F.1
Paterson, H.2
Marshall, C.J.3
-
28
-
-
0024406286
-
All ras proteins are polyisoprenylated but only some are palmitoylated
-
Hancock J.F., Magee A.I., Childs J.E., Marshall C.J. All ras proteins are polyisoprenylated but only some are palmitoylated. Cell 1989, 57:1167-1177.
-
(1989)
Cell
, vol.57
, pp. 1167-1177
-
-
Hancock, J.F.1
Magee, A.I.2
Childs, J.E.3
Marshall, C.J.4
-
29
-
-
0026037624
-
A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins
-
Hancock J.F., Cadwallader K., Paterson H., Marshall C.J. A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins. EMBO J. 1991, 10:4033-4039.
-
(1991)
EMBO J.
, vol.10
, pp. 4033-4039
-
-
Hancock, J.F.1
Cadwallader, K.2
Paterson, H.3
Marshall, C.J.4
-
30
-
-
78649821287
-
Segregation of negatively charged phospholipids by the polycationic and farnesylated membrane anchor of Kras
-
Janosi L., Gorfe A.A. Segregation of negatively charged phospholipids by the polycationic and farnesylated membrane anchor of Kras. Biophys. J. 2010, 99:3666-3674.
-
(2010)
Biophys. J.
, vol.99
, pp. 3666-3674
-
-
Janosi, L.1
Gorfe, A.A.2
-
31
-
-
0344585437
-
Lipid rafts: elusive or illusive?
-
Munro S. Lipid rafts: elusive or illusive?. Cell 2003, 115:377-388.
-
(2003)
Cell
, vol.115
, pp. 377-388
-
-
Munro, S.1
-
32
-
-
33745801153
-
Lipid rafts: contentious only from simplistic standpoints
-
Hancock J.F. Lipid rafts: contentious only from simplistic standpoints. Nat. Rev. Mol. Cell Biol. 2006, 7:456-462.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 456-462
-
-
Hancock, J.F.1
-
33
-
-
33847413103
-
Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer
-
Gorfe A.A., Hanzal-Bayer M., Abankwa D., Hancock J.F., McCammon J.A. Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer. J. Med. Chem. 2007, 50:674-684.
-
(2007)
J. Med. Chem.
, vol.50
, pp. 674-684
-
-
Gorfe, A.A.1
Hanzal-Bayer, M.2
Abankwa, D.3
Hancock, J.F.4
McCammon, J.A.5
-
35
-
-
50849107378
-
Mechanisms of Ras membrane organization and signalling: Ras on a rocker
-
Abankwa D., Gorfe A.A., Hancock J.F. Mechanisms of Ras membrane organization and signalling: Ras on a rocker. Cell Cycle 2008, 7:2667-2673.
-
(2008)
Cell Cycle
, vol.7
, pp. 2667-2673
-
-
Abankwa, D.1
Gorfe, A.A.2
Hancock, J.F.3
-
36
-
-
84898063580
-
The efficacy of Raf kinase recruitment to the GTPase H-ras depends on H-ras membrane conformer-specific nanoclustering
-
Guzman C., Solman M., Ligabue A., Blazevits O., Andrade D.M., Reymond L., Eggeling C., Abankwa D. The efficacy of Raf kinase recruitment to the GTPase H-ras depends on H-ras membrane conformer-specific nanoclustering. J. Biol. Chem. 2014, 289:9519-9533.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 9519-9533
-
-
Guzman, C.1
Solman, M.2
Ligabue, A.3
Blazevits, O.4
Andrade, D.M.5
Reymond, L.6
Eggeling, C.7
Abankwa, D.8
-
37
-
-
84867572593
-
The role of G-domain orientation and nucleotide state on the Ras isoform-specific membrane interaction
-
Kapoor S., Weise K., Erlkamp M., Triola G., Waldmann H., Winter R. The role of G-domain orientation and nucleotide state on the Ras isoform-specific membrane interaction. Eur. Biophys. J. 2012, 41:801-813.
-
(2012)
Eur. Biophys. J.
, vol.41
, pp. 801-813
-
-
Kapoor, S.1
Weise, K.2
Erlkamp, M.3
Triola, G.4
Waldmann, H.5
Winter, R.6
-
38
-
-
84856005311
-
Revealing conformational substates of lipidated N-Ras protein by pressure modulation
-
Kapoor S., Triola G., Vetter I.R., Erlkamp M., Waldmann H., Winter R. Revealing conformational substates of lipidated N-Ras protein by pressure modulation. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:460-465.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 460-465
-
-
Kapoor, S.1
Triola, G.2
Vetter, I.R.3
Erlkamp, M.4
Waldmann, H.5
Winter, R.6
-
39
-
-
78049448010
-
The distinct conformational dynamics of K-Ras and H-Ras A59G
-
Lukman S., Grant B.J., Gorfe A.A., Grant G.H., McCammon J.A. The distinct conformational dynamics of K-Ras and H-Ras A59G. PLoS Comput. Biol. 2010, 6.
-
(2010)
PLoS Comput. Biol.
, vol.6
-
-
Lukman, S.1
Grant, B.J.2
Gorfe, A.A.3
Grant, G.H.4
McCammon, J.A.5
-
40
-
-
58149279827
-
Activation of the MAPK module from different spatial locations generates distinct system outputs
-
Inder K., Harding A., Plowman S.J., Philips M.R., Parton R.G., Hancock J.F. Activation of the MAPK module from different spatial locations generates distinct system outputs. Mol. Biol. Cell 2008, 19:4776-4784.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4776-4784
-
-
Inder, K.1
Harding, A.2
Plowman, S.J.3
Philips, M.R.4
Parton, R.G.5
Hancock, J.F.6
-
41
-
-
0028241533
-
Activation of Raf as a result of recruitment to the plasma membrane
-
Stokoe D., Macdonald S.G., Cadwallader K., Symons M., Hancock J.F. Activation of Raf as a result of recruitment to the plasma membrane. Science 1994, 264:1463-1467.
-
(1994)
Science
, vol.264
, pp. 1463-1467
-
-
Stokoe, D.1
Macdonald, S.G.2
Cadwallader, K.3
Symons, M.4
Hancock, J.F.5
-
42
-
-
0028272507
-
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
-
Leevers S.J., Paterson H.F., Marshall C.J. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 1994, 369:411-414.
-
(1994)
Nature
, vol.369
, pp. 411-414
-
-
Leevers, S.J.1
Paterson, H.F.2
Marshall, C.J.3
-
43
-
-
12244270658
-
Organization in lipid membranes containing cholesterol
-
Veatch S.L., Keller S.L. Organization in lipid membranes containing cholesterol. Phys. Rev. Lett. 2002, 89:268101.
-
(2002)
Phys. Rev. Lett.
, vol.89
, pp. 268101
-
-
Veatch, S.L.1
Keller, S.L.2
-
44
-
-
0242385346
-
Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol
-
Veatch S.L., Keller S.L. Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol. Biophys. J. 2003, 85:3074-3083.
-
(2003)
Biophys. J.
, vol.85
, pp. 3074-3083
-
-
Veatch, S.L.1
Keller, S.L.2
-
45
-
-
36749056331
-
Critical fluctuations in domain-forming lipid mixtures
-
Veatch S.L., Soubias O., Keller S.L., Gawrisch K. Critical fluctuations in domain-forming lipid mixtures. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:17650-17655.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 17650-17655
-
-
Veatch, S.L.1
Soubias, O.2
Keller, S.L.3
Gawrisch, K.4
-
46
-
-
77957167810
-
Revitalizing membrane rafts: new tools and insights
-
Simons K., Gerl M.J. Revitalizing membrane rafts: new tools and insights. Nat. Rev. Mol. Cell Biol. 2010, 11:688-699.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 688-699
-
-
Simons, K.1
Gerl, M.J.2
-
47
-
-
0030949124
-
Functional rafts in cell membranes
-
Simons K., Ikonen E. Functional rafts in cell membranes. Nature 1997, 387:569-572.
-
(1997)
Nature
, vol.387
, pp. 569-572
-
-
Simons, K.1
Ikonen, E.2
-
49
-
-
84895770533
-
Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling
-
Ariotti N., Fernandez-Rojo M.A., Zhou Y., Hill M.M., Rodkey T.L., Inder K.L., Tanner L.B., Wenk M.R., Hancock J.F., Parton R.G. Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling. J. Cell Biol. 2014, 204:777-792.
-
(2014)
J. Cell Biol.
, vol.204
, pp. 777-792
-
-
Ariotti, N.1
Fernandez-Rojo, M.A.2
Zhou, Y.3
Hill, M.M.4
Rodkey, T.L.5
Inder, K.L.6
Tanner, L.B.7
Wenk, M.R.8
Hancock, J.F.9
Parton, R.G.10
-
50
-
-
84860857782
-
Nonsteroidal anti-inflammatory drugs alter the spatiotemporal organization of Ras proteins on the plasma membrane
-
Zhou Y., Cho K.J., Plowman S.J., Hancock J.F. Nonsteroidal anti-inflammatory drugs alter the spatiotemporal organization of Ras proteins on the plasma membrane. J. Biol. Chem. 2012, 287:16586-16595.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 16586-16595
-
-
Zhou, Y.1
Cho, K.J.2
Plowman, S.J.3
Hancock, J.F.4
-
51
-
-
0033145517
-
Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains
-
Roy S., Luetterforst R., Harding A., Apolloni A., Etheridge M., Stang E., Rolls B., Hancock J.F., Parton R.G. Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains. Nat. Cell Biol. 1999, 1:98-105.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 98-105
-
-
Roy, S.1
Luetterforst, R.2
Harding, A.3
Apolloni, A.4
Etheridge, M.5
Stang, E.6
Rolls, B.7
Hancock, J.F.8
Parton, R.G.9
-
52
-
-
78751545856
-
The MARCKS protein plays a critical role in phosphatidylinositol 4,5-bisphosphate metabolism and directed cell movement in vascular endothelial cells
-
Kalwa H., Michel T. The MARCKS protein plays a critical role in phosphatidylinositol 4,5-bisphosphate metabolism and directed cell movement in vascular endothelial cells. J. Biol. Chem. 2011, 286:2320-2330.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 2320-2330
-
-
Kalwa, H.1
Michel, T.2
-
53
-
-
84861325378
-
The lipid raft-associated protein CD98 is required for vaccinia virus endocytosis
-
Schroeder N., Chung C.S., Chen C.H., Liao C.L., Chang W. The lipid raft-associated protein CD98 is required for vaccinia virus endocytosis. J. Virol. 2012, 86:4868-4882.
-
(2012)
J. Virol.
, vol.86
, pp. 4868-4882
-
-
Schroeder, N.1
Chung, C.S.2
Chen, C.H.3
Liao, C.L.4
Chang, W.5
-
54
-
-
18944364523
-
PIP2 signaling in lipid domains: a critical re-evaluation
-
van Rheenen J., Achame E.M., Janssen H., Calafat J., Jalink K. PIP2 signaling in lipid domains: a critical re-evaluation. EMBO J. 2005, 24:1664-1673.
-
(2005)
EMBO J.
, vol.24
, pp. 1664-1673
-
-
van Rheenen, J.1
Achame, E.M.2
Janssen, H.3
Calafat, J.4
Jalink, K.5
-
55
-
-
0029935339
-
Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells
-
Ghosh S., Strum J.C., Sciorra V.A., Daniel L., Bell R.M. Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells. J. Biol. Chem. 1996, 271:8472-8480.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8472-8480
-
-
Ghosh, S.1
Strum, J.C.2
Sciorra, V.A.3
Daniel, L.4
Bell, R.M.5
-
56
-
-
38149094836
-
Membrane phosphatidylserine regulates surface charge and protein localization
-
Yeung T., Gilbert G.E., Shi J., Silvius J., Kapus A., Grinstein S. Membrane phosphatidylserine regulates surface charge and protein localization. Science 2008, 319:210-213.
-
(2008)
Science
, vol.319
, pp. 210-213
-
-
Yeung, T.1
Gilbert, G.E.2
Shi, J.3
Silvius, J.4
Kapus, A.5
Grinstein, S.6
-
57
-
-
84871538883
-
Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins
-
Cho K.J., Park J.H., Piggott A.M., Salim A.A., Gorfe A., Parton R.G., Capon R.J., Lacey E., Hancock J.F. Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins. J. Biol. Chem. 2012, 287(52):43573-43584.
-
(2012)
J. Biol. Chem.
, vol.287
, Issue.52
, pp. 43573-43584
-
-
Cho, K.J.1
Park, J.H.2
Piggott, A.M.3
Salim, A.A.4
Gorfe, A.5
Parton, R.G.6
Capon, R.J.7
Lacey, E.8
Hancock, J.F.9
-
58
-
-
84871909237
-
Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission
-
van der Hoeven D., Cho K.J., Ma X., Chigurupati S., Parton R.G., Hancock J.F. Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission. Mol. Cell. Biol. 2013, 33:237-251.
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 237-251
-
-
van der Hoeven, D.1
Cho, K.J.2
Ma, X.3
Chigurupati, S.4
Parton, R.G.5
Hancock, J.F.6
-
59
-
-
84861674702
-
Phosphatidylserine dynamics in cellular membranes
-
Kay J.G., Koivusalo M., Ma X., Wohland T., Grinstein S. Phosphatidylserine dynamics in cellular membranes. Mol. Biol. Cell 2012, 23:2198-2212.
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 2198-2212
-
-
Kay, J.G.1
Koivusalo, M.2
Ma, X.3
Wohland, T.4
Grinstein, S.5
-
60
-
-
79961113678
-
High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine
-
Fairn G.D., Schieber N.L., Ariotti N., Murphy S., Kuerschner L., Webb R.I., Grinstein S., Parton R.G. High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. J. Cell Biol. 2011, 194:257-275.
-
(2011)
J. Cell Biol.
, vol.194
, pp. 257-275
-
-
Fairn, G.D.1
Schieber, N.L.2
Ariotti, N.3
Murphy, S.4
Kuerschner, L.5
Webb, R.I.6
Grinstein, S.7
Parton, R.G.8
-
61
-
-
84872959202
-
Caveolae as plasma membrane sensors, protectors and organizers
-
Parton R.G., del Pozo M.A. Caveolae as plasma membrane sensors, protectors and organizers. Nat. Rev. Mol. Cell Biol. 2013, 14:98-112.
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 98-112
-
-
Parton, R.G.1
del Pozo, M.A.2
-
62
-
-
0037435608
-
Caveolin scaffolding region and the membrane binding region of SRC form lateral membrane domains
-
Wanaski S.P., Ng B.K., Glaser M. Caveolin scaffolding region and the membrane binding region of SRC form lateral membrane domains. Biochemistry 2003, 42:42-56.
-
(2003)
Biochemistry
, vol.42
, pp. 42-56
-
-
Wanaski, S.P.1
Ng, B.K.2
Glaser, M.3
-
63
-
-
37649011760
-
PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function
-
Hill M.M., Bastiani M., Luetterforst R., Kirkham M., Kirkham A., Nixon S.J., Walser P., Abankwa D., Oorschot V.M., Martin S., Hancock J.F., Parton R.G. PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. Cell 2008, 132:113-124.
-
(2008)
Cell
, vol.132
, pp. 113-124
-
-
Hill, M.M.1
Bastiani, M.2
Luetterforst, R.3
Kirkham, M.4
Kirkham, A.5
Nixon, S.J.6
Walser, P.7
Abankwa, D.8
Oorschot, V.M.9
Martin, S.10
Hancock, J.F.11
Parton, R.G.12
-
64
-
-
67349244346
-
SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function
-
McMahon K.A., Zajicek H., Li W.P., Peyton M.J., Minna J.D., Hernandez V.J., Luby-Phelps K., Anderson R.G. SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function. EMBO J. 2009, 28:1001-1015.
-
(2009)
EMBO J.
, vol.28
, pp. 1001-1015
-
-
McMahon, K.A.1
Zajicek, H.2
Li, W.P.3
Peyton, M.J.4
Minna, J.D.5
Hernandez, V.J.6
Luby-Phelps, K.7
Anderson, R.G.8
-
65
-
-
67649583182
-
MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes
-
Bastiani M., Liu L., Hill M.M., Jedrychowski M.P., Nixon S.J., Lo H.P., Abankwa D., Luetterforst R., Fernandez-Rojo M., Breen M.R., Gygi S.P., Vinten J., Walser P.J., North K.N., Hancock J.F., Pilch P.F., Parton R.G. MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. J. Cell Biol. 2009, 185:1259-1273.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 1259-1273
-
-
Bastiani, M.1
Liu, L.2
Hill, M.M.3
Jedrychowski, M.P.4
Nixon, S.J.5
Lo, H.P.6
Abankwa, D.7
Luetterforst, R.8
Fernandez-Rojo, M.9
Breen, M.R.10
Gygi, S.P.11
Vinten, J.12
Walser, P.J.13
North, K.N.14
Hancock, J.F.15
Pilch, P.F.16
Parton, R.G.17
-
66
-
-
67650072744
-
SDPR induces membrane curvature and functions in the formation of caveolae
-
Hansen C.G., Bright N.A., Howard G., Nichols B.J. SDPR induces membrane curvature and functions in the formation of caveolae. Nat. Cell Biol. 2009, 11:807-814.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 807-814
-
-
Hansen, C.G.1
Bright, N.A.2
Howard, G.3
Nichols, B.J.4
-
67
-
-
37649017003
-
PTRF triggers a cave in
-
Chadda R., Mayor S. PTRF triggers a cave in. Cell 2008, 132:23-24.
-
(2008)
Cell
, vol.132
, pp. 23-24
-
-
Chadda, R.1
Mayor, S.2
-
68
-
-
34249063885
-
Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases
-
Grande-Garcia A., Echarri A., de Rooij J., Alderson N.B., Waterman-Storer C.M., Valdivielso J.M., del Pozo M.A. Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases. J. Cell Biol. 2007, 177:683-694.
-
(2007)
J. Cell Biol.
, vol.177
, pp. 683-694
-
-
Grande-Garcia, A.1
Echarri, A.2
de Rooij, J.3
Alderson, N.B.4
Waterman-Storer, C.M.5
Valdivielso, J.M.6
del Pozo, M.A.7
-
69
-
-
84864025624
-
Structure-based reassessment of the caveolin signaling model: do caveolae regulate signaling through caveolin-protein interactions?
-
Collins B.M., Davis M.J., Hancock J.F., Parton R.G. Structure-based reassessment of the caveolin signaling model: do caveolae regulate signaling through caveolin-protein interactions?. Dev. Cell 2012, 23:11-20.
-
(2012)
Dev. Cell
, vol.23
, pp. 11-20
-
-
Collins, B.M.1
Davis, M.J.2
Hancock, J.F.3
Parton, R.G.4
-
70
-
-
8444221934
-
Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement
-
Sasaki A.T., Chun C., Takeda K., Firtel R.A. Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J. Cell Biol. 2004, 167:505-518.
-
(2004)
J. Cell Biol.
, vol.167
, pp. 505-518
-
-
Sasaki, A.T.1
Chun, C.2
Takeda, K.3
Firtel, R.A.4
-
71
-
-
33745607882
-
Feedback signaling controls leading-edge formation during chemotaxis
-
Charest P.G., Firtel R.A. Feedback signaling controls leading-edge formation during chemotaxis. Curr. Opin. Genet. Dev. 2006, 16:339-347.
-
(2006)
Curr. Opin. Genet. Dev.
, vol.16
, pp. 339-347
-
-
Charest, P.G.1
Firtel, R.A.2
-
72
-
-
77952920346
-
A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration
-
Charest P.G., Shen Z., Lakoduk A., Sasaki A.T., Briggs S.P., Firtel R.A. A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration. Dev. Cell 2010, 18:737-749.
-
(2010)
Dev. Cell
, vol.18
, pp. 737-749
-
-
Charest, P.G.1
Shen, Z.2
Lakoduk, A.3
Sasaki, A.T.4
Briggs, S.P.5
Firtel, R.A.6
-
73
-
-
78049410557
-
The anti-inflammatory drug indomethacin alters nanoclustering in synthetic and cell plasma membranes
-
Zhou Y., Plowman S.J., Lichtenberger L.M., Hancock J.F. The anti-inflammatory drug indomethacin alters nanoclustering in synthetic and cell plasma membranes. J. Biol. Chem. 2010, 285:35188-35195.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 35188-35195
-
-
Zhou, Y.1
Plowman, S.J.2
Lichtenberger, L.M.3
Hancock, J.F.4
-
74
-
-
77952472956
-
The nonsteroidal anti-inflammatory drug indomethacin induces heterogeneity in lipid membranes: potential implication for its diverse biological action
-
Zhou Y., Hancock J.F., Lichtenberger L.M. The nonsteroidal anti-inflammatory drug indomethacin induces heterogeneity in lipid membranes: potential implication for its diverse biological action. PLoS One 2010, 5:e8811.
-
(2010)
PLoS One
, vol.5
, pp. e8811
-
-
Zhou, Y.1
Hancock, J.F.2
Lichtenberger, L.M.3
|