-
1
-
-
50849107378
-
Mechanisms of Ras membrane organization and signalling: Ras on a rocker
-
Abankwa D, Gorfe AA, Hancock JF (2008a) Mechanisms of Ras membrane organization and signalling: Ras on a rocker. Cell Cycle 7:2667-2673
-
(2008)
Cell Cycle
, vol.7
, pp. 2667-2673
-
-
Abankwa, D.1
Gorfe, A.A.2
Hancock, J.F.3
-
2
-
-
40949130399
-
A novel switch region regulates H-Ras membrane orientation and signal output
-
Abankwa D, Hanzal-Bayer M, Ariotti N, Plowman SJ, Gorfe AA, Parton RG, McCammon JA, Hancock JF (2008b) A novel switch region regulates H-Ras membrane orientation and signal output. EMBO J 27:727-735
-
(2008)
EMBO J
, vol.27
, pp. 727-735
-
-
Abankwa, D.1
Hanzal-Bayer, M.2
Ariotti, N.3
Plowman, S.J.4
Gorfe, A.A.5
Parton, R.G.6
McCammon, J.A.7
Hancock, J.F.8
-
3
-
-
75749150934
-
Ras membrane orientation and nanodomain localization generate isoform diversity
-
Abankwa D, Gorfe AA, Inder K, Hancock JF (2010) Ras membrane orientation and nanodomain localization generate isoform diversity. Proc Natl Acad Sci USA 107:1130-1135
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1130-1135
-
-
Abankwa, D.1
Gorfe, A.A.2
Inder, K.3
Hancock, J.F.4
-
4
-
-
78650627501
-
Membrane docking of the C2 domain from protein kinase C alpha as seen by polarized ATR-IR. The role of PIP2
-
Ausili A, Corbalan-Garcia S, Gomez-Fernandez JC, Marsh D (2011) Membrane docking of the C2 domain from protein kinase C alpha as seen by polarized ATR-IR. The role of PIP2. Biochim Biophys Acta Biomembr 1808:684-695
-
(2011)
Biochim Biophys Acta Biomembr
, vol.1808
, pp. 684-695
-
-
Ausili, A.1
Corbalan-Garcia, S.2
Gomez-Fernandez, J.C.3
Marsh, D.4
-
5
-
-
0030422901
-
Orientational order determination by internal reflection infrared spectroscopy
-
Axelsen PH, Citra MJ (1996) Orientational order determination by internal reflection infrared spectroscopy. Prog Biophys Mol Biol 66:227-253
-
(1996)
Prog Biophys Mol Biol
, vol.66
, pp. 227-253
-
-
Axelsen, P.H.1
Citra, M.J.2
-
6
-
-
0032909033
-
Membrane helix orientation from linear dichroism of infrared attenuated total reflection spectra
-
Bechinger B, Ruysschaert JM, Goormaghtigh E (1999) Membrane helix orientation from linear dichroism of infrared attenuated total reflection spectra. Biophys J 76:552-563
-
(1999)
Biophys J
, vol.76
, pp. 552-563
-
-
Bechinger, B.1
Ruysschaert, J.M.2
Goormaghtigh, E.3
-
7
-
-
0024376173
-
Ras oncogenes in human cancer - A review
-
Bos JL (1989) Ras oncogenes in human cancer - a review. Cancer Res 49:4682-4689
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
8
-
-
34247244755
-
Membrane binding of a lipidated N-Ras protein studied in lipid monolayers
-
Bringezu F, Majerowicz M, Wen SY, Reuther G, Tan KT, Kuhlmann J, Waldmann H, Huster D (2007) Membrane binding of a lipidated N-Ras protein studied in lipid monolayers. Eur Biophys J 36:491-498
-
(2007)
Eur Biophys J
, vol.36
, pp. 491-498
-
-
Bringezu, F.1
Majerowicz, M.2
Wen, S.Y.3
Reuther, G.4
Tan, K.T.5
Kuhlmann, J.6
Waldmann, H.7
Huster, D.8
-
9
-
-
33750192397
-
Lipidated Ras and Rab peptides and proteins synthesis structure, and function
-
Brunsveld L, Kuhlmann J, Alexandrov K, Wittinghofer A, Goody RS, Waldmann H (2006) Lipidated Ras and Rab peptides and proteins - synthesis, structure, and function. Angew Chem Int Edit 45:6622-6646
-
(2006)
Angew Chem Int Edit
, vol.45
, pp. 6622-6646
-
-
Brunsveld, L.1
Kuhlmann, J.2
Alexandrov, K.3
Wittinghofer, A.4
Goody, R.S.5
Waldmann, H.6
-
10
-
-
58149197889
-
Membrane binding of lipidated Ras peptides and proteins: The structural point of view
-
Brunsveld L, Waldmann H, Huster D (2009) Membrane binding of lipidated Ras peptides and proteins: the structural point of view. Biochim Biophys Acta Biomembr 1788:273-288
-
(2009)
Biochim Biophys Acta Biomembr
, vol.1788
, pp. 273-288
-
-
Brunsveld, L.1
Waldmann, H.2
Huster, D.3
-
11
-
-
77956017871
-
Synthesis of the Rheb and K-Ras4B GTPases
-
Chen YX, Koch S, Uhlenbrock K, Weise K, Das D, Gremer L, Brunsveld L, Wittinghofer A, Winter R, Triola G, Waldmann H (2010) Synthesis of the Rheb and K-Ras4B GTPases. Angew Chem Int Edit 49:6090-6095
-
(2010)
Angew Chem Int Edit
, vol.49
, pp. 6090-6095
-
-
Chen, Y.X.1
Koch, S.2
Uhlenbrock, K.3
Weise, K.4
Das, D.5
Gremer, L.6
Brunsveld, L.7
Wittinghofer, A.8
Winter, R.9
Triola, G.10
Waldmann, H.11
-
12
-
-
84856696581
-
Detection of lipid raft domains in neutral and anionic Langmuir monolayers and bilayers of complex lipid composition
-
Evers F, Jeworrek C, Weise K, Tolan M, Winter R (2012) Detection of lipid raft domains in neutral and anionic Langmuir monolayers and bilayers of complex lipid composition. Soft Matter 8:2170-2175
-
(2012)
Soft Matter
, vol.8
, pp. 2170-2175
-
-
Evers, F.1
Jeworrek, C.2
Weise, K.3
Tolan, M.4
Winter, R.5
-
13
-
-
0032968077
-
Attenuated total reflection infrared spectroscopy of proteins and lipids in biological membranes
-
Goormaghtigh E, Raussens V, Ruysschaert JM (1999) Attenuated total reflection infrared spectroscopy of proteins and lipids in biological membranes. Biochim Biophys Acta Rev Biomembr 1422:105-185
-
(1999)
Biochim Biophys Acta Rev Biomembr
, vol.1422
, pp. 105-185
-
-
Goormaghtigh, E.1
Raussens, V.2
Ruysschaert, J.M.3
-
14
-
-
35048822834
-
H-Ras protein in a bilayer: Interaction and structure perturbation
-
Gorfe AA, Babakhani A, McCammon JA (2007a) H-Ras protein in a bilayer: interaction and structure perturbation. J Am Chem Soc 129:12280-12286
-
(2007)
J Am Chem Soc
, vol.129
, pp. 12280-12286
-
-
Gorfe, A.A.1
Babakhani, A.2
McCammon, J.A.3
-
15
-
-
33847413103
-
Structure and dynamics of the full-length lipidmodified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer
-
Gorfe AA, Hanzal-Bayer M, Abankwa D, Hancock JF, McCammon JA (2007b) Structure and dynamics of the full-length lipidmodified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer. J Med Chem 50:674-684
-
(2007)
J Med Chem
, vol.50
, pp. 674-684
-
-
Gorfe, A.A.1
Hanzal-Bayer, M.2
Abankwa, D.3
Hancock, J.F.4
McCammon, J.A.5
-
16
-
-
55949118981
-
Secondary structure of lipidated Ras bound to a lipid bilayer
-
Güldenhaupt J, Adiguzel Y, Kuhlmann J, Waldmann H, Kotting C, Gerwert K (2008) Secondary structure of lipidated Ras bound to a lipid bilayer. FEBS J 275:5910-5918
-
(2008)
FEBS J
, vol.275
, pp. 5910-5918
-
-
Güldenhaupt, J.1
Adiguzel, Y.2
Kuhlmann, J.3
Waldmann, H.4
Kotting, C.5
Gerwert, K.6
-
17
-
-
0037542854
-
Ras proteins: Different signals from different locations
-
Hancock JF (2003) Ras proteins: different signals from different locations. Nat Rev Mol Cell Biol 4:373-384
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 373-384
-
-
Hancock, J.F.1
-
18
-
-
22144479017
-
Ras plasma membrane signaling platforms
-
Hancock JF, Parton RG (2005) Ras plasma membrane signaling platforms. Biochem J 389:1-11
-
(2005)
Biochem J
, vol.389
, pp. 1-11
-
-
Hancock, J.F.1
Parton, R.G.2
-
19
-
-
0025013547
-
A Polybasic domain or palmitoylation is required in addition to the Caax motif to localize p21 Ras to the plasma membrane
-
Hancock JF, Paterson H, Marshall CJ (1990) A Polybasic domain or palmitoylation is required in addition to the Caax motif to localize p21 Ras to the plasma membrane. Cell 63:133-139
-
(1990)
Cell
, vol.63
, pp. 133-139
-
-
Hancock, J.F.1
Paterson, H.2
Marshall, C.J.3
-
20
-
-
0026021456
-
Methylation and proteolysis are essential for efficient membrane binding of prenylated p21 K-Ras(B)
-
Hancock JF, Cadwallader K, Marshall CJ (1991) Methylation and proteolysis are essential for efficient membrane binding of prenylated p21 K-Ras(B). EMBO J 10:641-646
-
(1991)
EMBO J
, vol.10
, pp. 641-646
-
-
Hancock, J.F.1
Cadwallader, K.2
Marshall, C.J.3
-
22
-
-
0035857550
-
H-1 high-resolution magic angle spinning NMR spectroscopy for the investigation of a Ras lipopeptide in a lipid membrane
-
Huster D, Kuhn K, Kadereit D, Waldmann H, Arnold K (2001) H-1 high-resolution magic angle spinning NMR spectroscopy for the investigation of a Ras lipopeptide in a lipid membrane. Angew Chem Int Edit 40:1056-1058
-
(2001)
Angew Chem Int Edit
, vol.40
, pp. 1056-1058
-
-
Huster, D.1
Kuhn, K.2
Kadereit, D.3
Waldmann, H.4
Arnold, K.5
-
23
-
-
79951559073
-
Temperature-pressure phase diagram of a heterogeneous anionic model biomembrane system: Results from a combined calorimetry, spectroscopy and microscopy study
-
Kapoor S, Werkmüller A, Denter C, Zhai Y, Markgraf J, Weise K, Opitz N, Winter R (2011) Temperature-pressure phase diagram of a heterogeneous anionic model biomembrane system: results from a combined calorimetry, spectroscopy and microscopy study. Biochim Biophys Acta Biomembr 1808:1187-1195
-
(2011)
Biochim Biophys Acta Biomembr
, vol.1808
, pp. 1187-1195
-
-
Kapoor, S.1
Werkmüller, A.2
Denter, C.3
Zhai, Y.4
Markgraf, J.5
Weise, K.6
Opitz, N.7
Winter, R.8
-
24
-
-
84856005311
-
Kapoor S,TriolaG,Vetter IR,ErlkampM,WaldmannH,WinterR(2012) Revealing conformational substates of lipidated N-Ras protein by pressure modulation
-
Kapoor S,TriolaG,Vetter IR,ErlkampM,WaldmannH,WinterR(2012) Revealing conformational substates of lipidated N-Ras protein by pressure modulation. Proc Natl Acad Sci USA 109:460-465
-
Proc Natl Acad Sci USA
, vol.109
, pp. 460-465
-
-
-
26
-
-
0035857413
-
Synthesis of functional Ras lipoproteins and fluorescent derivatives
-
Kuhn K, Owen DJ, Bader B, Wittinghofer A, Kuhlmann J, Waldmann H (2001) Synthesis of functional Ras lipoproteins and fluorescent derivatives. J Am Chem Soc 123:1023-1035
-
(2001)
J Am Chem Soc
, vol.123
, pp. 1023-1035
-
-
Kuhn, K.1
Owen, D.J.2
Bader, B.3
Wittinghofer, A.4
Kuhlmann, J.5
Waldmann, H.6
-
27
-
-
0026511938
-
Structures of the subgel phases of n-saturated diacyl phosphatidylcholine bilayers: FTIR spectroscopic studies of 13C=O and 2H labeled lipids
-
Lewis RN, McElhaney RN (1992) Structures of the subgel phases of n-saturated diacyl phosphatidylcholine bilayers: FTIR spectroscopic studies of 13C=O and 2H labeled lipids. Biophys J 61:63-77
-
(1992)
Biophys J
, vol.61
, pp. 63-77
-
-
Lewis, R.N.1
McElhaney, R.N.2
-
28
-
-
78049448010
-
The distinct conformational dynamics of K-Ras and H-Ras A59G
-
Lukman S, Grant BJ, Gorfe AA, Grant GH, McCammon JA (2010) The distinct conformational dynamics of K-Ras and H-Ras A59G. PLoS Comput Biol 6:e1000922
-
(2010)
PLoS Comput Biol
, vol.6
-
-
Lukman, S.1
Grant, B.J.2
Gorfe, A.A.3
Grant, G.H.4
McCammon, J.A.5
-
29
-
-
0032734050
-
Quantitation of secondary structure in ATR infrared spectroscopy
-
Marsh D (1999) Quantitation of secondary structure in ATR infrared spectroscopy. Biophys J 77:2630-2637
-
(1999)
Biophys J
, vol.77
, pp. 2630-2637
-
-
Marsh, D.1
-
30
-
-
33746858605
-
Insertion of lipidated Ras proteins into lipid monolayers studied by infrared reflection absorption spectroscopy (IRRAS)
-
Meister A, Nicolini C, Waldmann H, Kuhlmann J, Kerth A, Winter R, Blume A (2006) Insertion of lipidated Ras proteins into lipid monolayers studied by infrared reflection absorption spectroscopy (IRRAS). Biophys J 91:1388-1401
-
(2006)
Biophys J
, vol.91
, pp. 1388-1401
-
-
Meister, A.1
Nicolini, C.2
Waldmann, H.3
Kuhlmann, J.4
Kerth, A.5
Winter, R.6
Blume, A.7
-
31
-
-
77449130066
-
Infrared reflectionabsorption spectroscopy: Principles and applications to lipid-protein interaction in Langmuir films
-
Mendelsohn R, Mao GR, Flach CR (2010) Infrared reflectionabsorption spectroscopy: principles and applications to lipid-protein interaction in Langmuir films. Biochim Biophys Acta Biomembr 1798:788-800
-
(2010)
Biochim Biophys Acta Biomembr
, vol.1798
, pp. 788-800
-
-
Mendelsohn, R.1
Mao, G.R.2
Flach, C.R.3
-
33
-
-
0017194357
-
Studies on membrane-fusion. 2. Induction of fusion in pure phospholipids membranes by calcium ions and other divalent metals
-
Papahadjopoulos D, Vail WJ, Pangborn WA, Poste G (1976) Studies on membrane-fusion. 2. Induction of fusion in pure phospholipids membranes by calcium ions and other divalent metals. Biochim Biophys Acta 448:265-283
-
(1976)
Biochim Biophys Acta
, vol.448
, pp. 265-283
-
-
Papahadjopoulos, D.1
Vail, W.J.2
Pangborn, W.A.3
Poste, G.4
-
34
-
-
0037455589
-
Direct visualization of Ras proteins in spatially distinct cell surface microdomains
-
Prior IA, Muncke C, Parton RG, Hancock JF (2003) Direct visualization of Ras proteins in spatially distinct cell surface microdomains. J Cell Biol 160:165-170
-
(2003)
J Cell Biol
, vol.160
, pp. 165-170
-
-
Prior, I.A.1
Muncke, C.2
Parton, R.G.3
Hancock, J.F.4
-
35
-
-
33846207546
-
Deregulated Ras signaling in developmental disorders: New tricks for an old dog
-
Shannon K
-
Schubbert S, Bollag G, Shannon K (2007) Deregulated Ras signaling in developmental disorders: new tricks for an old dog. Curr Opin Genet Dev 17:15-22
-
(2007)
Curr Opin Genet Dev
, vol.17
, pp. 15-22
-
-
Schubbert, S.1
Bollag, G.2
-
37
-
-
0026443739
-
Interfacial conformation of dipalmitoylglycerol and dipalmitoylphosphatidylcholine in phospholipid bilayers
-
Smith SO, Kustanovich I, Bhamidipati S, Salmon A, Hamilton JA (1992) Interfacial conformation of dipalmitoylglycerol and dipalmitoylphosphatidylcholine in phospholipid bilayers. Biochemistry 31:11660-11664
-
(1992)
Biochemistry
, vol.31
, pp. 11660-11664
-
-
Smith, S.O.1
Kustanovich, I.2
Bhamidipati, S.3
Salmon, A.4
Hamilton, J.A.5
-
38
-
-
34547561587
-
Plasma membrane nanoswitches generate high fidelity Ras signal transduction
-
Tian TH, Harding A, Inder K, Plowman S, Parton RG, Hancock JF (2007) Plasma membrane nanoswitches generate high fidelity Ras signal transduction. Nat Cell Biol 9:905-960
-
(2007)
Nat Cell Biol
, vol.9
, pp. 905-960
-
-
Tian, T.H.1
Harding, A.2
Inder, K.3
Plowman, S.4
Parton, R.G.5
Hancock, J.F.6
-
39
-
-
70350604271
-
The lipid modifications of Ras that sense membrane environments and induce local enrichment
-
Vogel A, Reuther G, Weise K, Triola G, Nikolaus J, Tan KT, Nowak C, Herrmann A, Waldmann H, Winter R, Huster D (2009) The lipid modifications of Ras that sense membrane environments and induce local enrichment. Angew Chem Int Edit 48:8784-8787
-
(2009)
Angew Chem Int Edit
, vol.48
, pp. 8784-8787
-
-
Vogel, A.1
Reuther, G.2
Weise, K.3
Triola, G.4
Nikolaus, J.5
Tan, K.T.6
Nowak, C.7
Herrmann, A.8
Waldmann, H.9
Winter, R.10
Huster, D.11
-
40
-
-
0029809315
-
What's new in ras genes? Physiological role of ras genes in signal transduction and significance of ras gene activation in tumorigenesis
-
Waldmann V, Rabes HM (1996) What's new in ras genes? Physiological role of ras genes in signal transduction and significance of ras gene activation in tumorigenesis. Pathol Res Pract 192:883-891
-
(1996)
Pathol Res Pract
, vol.192
, pp. 883-891
-
-
Waldmann, V.1
Rabes, H.M.2
-
41
-
-
0035844149
-
Differential activation of the pac pathway by Ha-Ras and K-Ras
-
Walsh AB, Bar-Sagi D (2001) Differential activation of the pac pathway by Ha-Ras and K-Ras. J Biol Chem 276:15609-15615
-
(2001)
J Biol Chem
, vol.276
, pp. 15609-15615
-
-
Walsh, A.B.1
Bar-Sagi, D.2
-
42
-
-
63149129301
-
Influence of the lipidation motif on the partitioning and association of N-Ras in model membrane subdomains
-
Weise K, Triola G, Brunsveld L, Waldmann H, Winter R (2009) Influence of the lipidation motif on the partitioning and association of N-Ras in model membrane subdomains. J Am Chem Soc 131:1557-1564
-
(2009)
J Am Chem Soc
, vol.131
, pp. 1557-1564
-
-
Weise, K.1
Triola, G.2
Brunsveld, L.3
Waldmann, H.4
Winter, R.5
-
43
-
-
79851483766
-
Membranemediated induction and sorting of K-Ras microdomain signaling platforms
-
Weise K, Kapoor S, Denter C, Nikolaus J, Opitz N, Koch S, Triola G, Herrmann A, Waldmann H, Winter R (2011) Membranemediated induction and sorting of K-Ras microdomain signaling platforms. J Am Chem Soc 133:880-887
-
(2011)
J Am Chem Soc
, vol.133
, pp. 880-887
-
-
Weise, K.1
Kapoor, S.2
Denter, C.3
Nikolaus, J.4
Opitz, N.5
Koch, S.6
Triola, G.7
Herrmann, A.8
Waldmann, H.9
Winter, R.10
-
44
-
-
0021170342
-
The p21 Ras C-terminus is required for transformation and membrane association
-
Willumsen BM, Christensen A, Hubbert NL, Papageorge AG, Lowy DR (1984) The p21 Ras C-terminus is required for transformation and membrane association. Nature 310:583-586
-
(1984)
Nature
, vol.310
, pp. 583-586
-
-
Willumsen, B.M.1
Christensen, A.2
Hubbert, N.L.3
Papageorge, A.G.4
Lowy, D.R.5
-
45
-
-
0019828883
-
Solid-state C-13 nuclear magnetic-resonance of the lecithin gel to liquid-crystalline phase-transition
-
Wittebort RJ, Schmidt CF, Griffin RG (1981) Solid-state C-13 nuclear magnetic-resonance of the lecithin gel to liquid-crystalline phase-transition. Biochemistry 20:4223-4228
-
(1981)
Biochemistry
, vol.20
, pp. 4223-4228
-
-
Wittebort, R.J.1
Schmidt, C.F.2
Griffin, R.G.3
-
46
-
-
0025740753
-
The structure of Ras protein - Amodel for a universal molecular switch
-
Wittinghofer A, Pai EF (1991) The structure of Ras protein - amodel for a universal molecular switch. Trends Biochem Sci 16:382-387
-
(1991)
Trends Biochem Sci
, vol.16
, pp. 382-387
-
-
Wittinghofer, A.1
Pai, E.F.2
-
47
-
-
0034605862
-
Ras - A molecular switch involved in tumor formation
-
Wittinghofer A, Waldmann H (2000) Ras - a molecular switch involved in tumor formation. Angew Chem Int Edit 39:4193-4214
-
(2000)
Angew Chem Int Edit
, vol.39
, pp. 4193-4214
-
-
Wittinghofer, A.1
Waldmann, H.2
-
48
-
-
0032508517
-
Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase
-
Yan J, Roy S, Apolloni A, Lane A, Hancock JF (1998) Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase. J Biol Chem 273:24052-24056
-
(1998)
J Biol Chem
, vol.273
, pp. 24052-24056
-
-
Yan, J.1
Roy, S.2
Apolloni, A.3
Lane, A.4
Hancock, J.F.5
-
49
-
-
79955963495
-
Applications of pressure perturbation calorimetry in biophysical studies
-
Zhai Y, Okoro L, Cooper A, Winter R (2011) Applications of pressure perturbation calorimetry in biophysical studies. Biophys Chem 156:13-23
-
(2011)
Biophys Chem
, vol.156
, pp. 13-23
-
-
Zhai, Y.1
Okoro, L.2
Cooper, A.3
Winter, R.4
|