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Volumn 24, Issue 9, 2005, Pages 1664-1673

PIP2 signaling in lipid domains: A critical re-evaluation

Author keywords

Fluorescence resonance energy transfer; G protein coupled receptor; PIP 2; Rafts; Triton X 100

Indexed keywords

CHOLESTEROL; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR; NEUROKININ 2 RECEPTOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; BETA CYCLODEXTRIN DERIVATIVE; METHYL BETA CYCLODEXTRIN; METHYL-BETA-CYCLODEXTRIN;

EID: 18944364523     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600655     Document Type: Article
Times cited : (163)

References (54)
  • 1
    • 0028943362 scopus 로고
    • C-terminal truncation of the neurokinin-2 receptor causes enhanced and sustained agonist-induced signalling. Role of receptor phosphorylation in signal attenuation
    • Alblas J, van Etten I, Khanum A, Moolenaar WH (1995) C-terminal truncation of the neurokinin-2 receptor causes enhanced and sustained agonist-induced signalling. Role of receptor phosphorylation in signal attenuation. J Biol Chem 270: 8944-8951
    • (1995) J Biol Chem , vol.270 , pp. 8944-8951
    • Alblas, J.1    Van Etten, I.2    Khanum, A.3    Moolenaar, W.H.4
  • 2
    • 0019427474 scopus 로고
    • Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts
    • Basu SK, Goldstein JL, Anderson RG, Brown MS (1981) Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts. Cell 24: 493-502
    • (1981) Cell , vol.24 , pp. 493-502
    • Basu, S.K.1    Goldstein, J.L.2    Anderson, R.G.3    Brown, M.S.4
  • 3
    • 0021750054 scopus 로고
    • Inositol trisphosphate, a novel second messenger in cellular signal transduction
    • Berridge MJ, Irvine RF (1984) Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature 312: 315-321
    • (1984) Nature , vol.312 , pp. 315-321
    • Berridge, M.J.1    Irvine, R.F.2
  • 4
    • 0030848105 scopus 로고    scopus 로고
    • Human monocytes and neutrophils store transforming growth factor-alpha in a subpopulation of cytoplasmic granules
    • Calafat J, Janssen H, Stahle-Backdahl M, Zuurbier AE, Knol EF, Egesten A (1997) Human monocytes and neutrophils store transforming growth factor-alpha in a subpopulation of cytoplasmic granules. Blood 90: 1255-1266
    • (1997) Blood , vol.90 , pp. 1255-1266
    • Calafat, J.1    Janssen, H.2    Stahle-Backdahl, M.3    Zuurbier, A.E.4    Knol, E.F.5    Egesten, A.6
  • 6
    • 0035881755 scopus 로고    scopus 로고
    • New EMBO members' review: Actin cytoskeleton regulation through modulation of PI(4,5)P(2) rafts
    • Caroni P (2001) New EMBO members' review: actin cytoskeleton regulation through modulation of PI(4,5)P(2) rafts. EMBO J 20: 4332-4336
    • (2001) EMBO J , vol.20 , pp. 4332-4336
    • Caroni, P.1
  • 7
    • 7244250134 scopus 로고    scopus 로고
    • Dynamic confinement of NK2 receptors in the plasma membrane: Improved FRAP analysis and biological relevance
    • Cezanne L, Lecat S, Lagane B, Millot C, Vollmer JY, Matthes H, Galzi JL, Lopez A (2004) Dynamic confinement of NK2 receptors in the plasma membrane: improved FRAP analysis and biological relevance. J Biol Chem 279: 45057-45067
    • (2004) J Biol Chem , vol.279 , pp. 45057-45067
    • Cezanne, L.1    Lecat, S.2    Lagane, B.3    Millot, C.4    Vollmer, J.Y.5    Matthes, H.6    Galzi, J.L.7    Lopez, A.8
  • 8
    • 0442276428 scopus 로고    scopus 로고
    • Detergents as tools for the purification and classification of lipid rafts
    • Chamberlain LH (2004) Detergents as tools for the purification and classification of lipid rafts. FEBS Lett 559: 1-5
    • (2004) FEBS Lett , vol.559 , pp. 1-5
    • Chamberlain, L.H.1
  • 9
    • 0034677631 scopus 로고    scopus 로고
    • PIP2 and PIP3: Complex roles at the cell surface
    • Czech MP (2000) PIP2 and PIP3: complex roles at the cell surface. Cell 100: 603-606
    • (2000) Cell , vol.100 , pp. 603-606
    • Czech, M.P.1
  • 10
    • 0035213859 scopus 로고    scopus 로고
    • Agonist-stimulated and tonic internalization of metabotropic glutamate receptor la in human embryonic kidney 293 cells: Agonist-stimulated endocytosis is beta-arrestin1 isoform-specific
    • Dale LB, Bhattacharya M, Seachrist JL, Anborgh PH, Ferguson SS (2001) Agonist-stimulated and tonic internalization of metabotropic glutamate receptor la in human embryonic kidney 293 cells: agonist-stimulated endocytosis is beta-arrestin1 isoform-specific. Mol Pharmacol 60: 1243-1253
    • (2001) Mol Pharmacol , vol.60 , pp. 1243-1253
    • Dale, L.B.1    Bhattacharya, M.2    Seachrist, J.L.3    Anborgh, P.H.4    Ferguson, S.S.5
  • 11
    • 0037959071 scopus 로고    scopus 로고
    • The state of lipid rafts: From model membranes to cells
    • Edidin M (2003) The state of lipid rafts: from model membranes to cells. Annu Rev Biophys Biomol Struct 32: 257-283
    • (2003) Annu Rev Biophys Biomol Struct , vol.32 , pp. 257-283
    • Edidin, M.1
  • 12
    • 1542399850 scopus 로고    scopus 로고
    • Lipid raft proteins have a random distribution during localized activation of the T-cell receptor
    • Glebov OO, Nichols BJ (2004) Lipid raft proteins have a random distribution during localized activation of the T-cell receptor. Nat Cell Biol 6: 238-243
    • (2004) Nat Cell Biol , vol.6 , pp. 238-243
    • Glebov, O.O.1    Nichols, B.J.2
  • 13
    • 0036841874 scopus 로고    scopus 로고
    • Triton promotes domain formation in lipid raft mixtures
    • Heerklotz H (2002) Triton promotes domain formation in lipid raft mixtures. Biophys J 83: 2693-2701
    • (2002) Biophys J , vol.83 , pp. 2693-2701
    • Heerklotz, H.1
  • 14
    • 0035808040 scopus 로고    scopus 로고
    • The complex and intriguing lives of PIP2 with ion channels and transporters
    • Hilgemann DW, Feng S, Nasuhoglu C (2001) The complex and intriguing lives of PIP2 with ion channels and transporters. Sci STKE 2001: RE19
    • (2001) Sci STKE , vol.2001
    • Hilgemann, D.W.1    Feng, S.2    Nasuhoglu, C.3
  • 15
    • 0032497831 scopus 로고    scopus 로고
    • PIPkins1, their substrates and their products: New functions for old enzymes
    • Hinchliffe KA, Ciruela A, Irvine RF (1998) PIPkins1, their substrates and their products: new functions for old enzymes. Biochim Biophys Acta 1436: 87-104
    • (1998) Biochim Biophys Acta , vol.1436 , pp. 87-104
    • Hinchliffe, K.A.1    Ciruela, A.2    Irvine, R.F.3
  • 16
    • 0029899011 scopus 로고    scopus 로고
    • Phosphoinositides and phosphoinositide-utilizing enzymes in detergent-insoluble lipid domains
    • Hope HR, Pike LJ (1996) Phosphoinositides and phosphoinositide-utilizing enzymes in detergent-insoluble lipid domains. Mol Biol Cell 7: 843-851
    • (1996) Mol Biol Cell , vol.7 , pp. 843-851
    • Hope, H.R.1    Pike, L.J.2
  • 17
    • 1242316984 scopus 로고    scopus 로고
    • Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src. Implications for a role of lipid microdomains
    • Hur EM, Park YS, Lee BD, Jang IH, Kim HS, Kim TD, Suh PG, Ryu SH, Kim KT (2004) Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src. Implications for a role of lipid microdomains. J Biol Chem 279: 5852-5860
    • (2004) J Biol Chem , vol.279 , pp. 5852-5860
    • Hur, E.M.1    Park, Y.S.2    Lee, B.D.3    Jang, I.H.4    Kim, H.S.5    Kim, T.D.6    Suh, P.G.7    Ryu, S.H.8    Kim, K.T.9
  • 18
    • 3543074534 scopus 로고    scopus 로고
    • Cytoskeletal regulation: Rich in lipids
    • Janmey PA, Lindberg U (2004) Cytoskeletal regulation: rich in lipids. Nat Rev Mol Cell Biol 5: 658-666
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 658-666
    • Janmey, P.A.1    Lindberg, U.2
  • 19
    • 0032514258 scopus 로고    scopus 로고
    • Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100Å using imaging fluorescence resonance energy transfer
    • Kenworthy AK, Edidin M (1998) Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100Å using imaging fluorescence resonance energy transfer. J Cell Biol 142: 69-84
    • (1998) J Cell Biol , vol.142 , pp. 69-84
    • Kenworthy, A.K.1    Edidin, M.2
  • 20
    • 0034075971 scopus 로고    scopus 로고
    • High-resolution FRET microscopy of cholera toxin B-subunit and GPI-anchored proteins in cell plasma membranes
    • Kenworthy AK, Petranova N, Edidin M (2000) High-resolution FRET microscopy of cholera toxin B-subunit and GPI-anchored proteins in cell plasma membranes. Mol Biol Cell 11: 1645-1655
    • (2000) Mol Biol Cell , vol.11 , pp. 1645-1655
    • Kenworthy, A.K.1    Petranova, N.2    Edidin, M.3
  • 21
    • 4344624896 scopus 로고    scopus 로고
    • Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating gamma-aminobutyric acid type A receptor membrane trafficking
    • Kittler JT, Thomas P, Tretter V, Bogdanov YD, Haucke V, Smart TG, Moss SJ (2004) Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating gamma-aminobutyric acid type A receptor membrane trafficking. Proc Natl Acad Sci USA 101: 12736-12741
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 12736-12741
    • Kittler, J.T.1    Thomas, P.2    Tretter, V.3    Bogdanov, Y.D.4    Haucke, V.5    Smart, T.G.6    Moss, S.J.7
  • 22
    • 0037013148 scopus 로고    scopus 로고
    • Role of phosphatidylinositol(4,5)bisphosphate organization in membrane transport by the Unc104 kinesin motor
    • Klopfenstein DR, Tomishige M, Stuurman N, Vale RD (2002) Role of phosphatidylinositol(4,5)bisphosphate organization in membrane transport by the Unc104 kinesin motor. Cell 109: 347-358
    • (2002) Cell , vol.109 , pp. 347-358
    • Klopfenstein, D.R.1    Tomishige, M.2    Stuurman, N.3    Vale, R.D.4
  • 23
    • 0022619414 scopus 로고
    • The relationship of hormone-sensitive and hormone-insensitive phosphatidylinositol to phosphatidylinositol 4,5-bisphosphate in the WRK-1 cell
    • Koreh K, Monaco ME (1986) The relationship of hormone-sensitive and hormone-insensitive phosphatidylinositol to phosphatidylinositol 4,5-bisphosphate in the WRK-1 cell. J Biol Chem 261: 88-91
    • (1986) J Biol Chem , vol.261 , pp. 88-91
    • Koreh, K.1    Monaco, M.E.2
  • 24
    • 0034717707 scopus 로고    scopus 로고
    • GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasma-lemmal rafts, and regulate cell cortex actin dynamics through a common mechanism
    • Laux T, Fukami K, Thelen M, Golub T, Frey D, Caroni P (2000) GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasma-lemmal rafts, and regulate cell cortex actin dynamics through a common mechanism. J Cell Biol 149: 1455-1472
    • (2000) J Cell Biol , vol.149 , pp. 1455-1472
    • Laux, T.1    Fukami, K.2    Thelen, M.3    Golub, T.4    Frey, D.5    Caroni, P.6
  • 25
    • 0032576969 scopus 로고    scopus 로고
    • Compartmentalization of phosphatidylinositol 4,5-bisphosphate in low-density membrane domains in the absence of caveolin
    • Liu Y, Casey L, Pike LJ (1998) Compartmentalization of phosphatidylinositol 4,5-bisphosphate in low-density membrane domains in the absence of caveolin. Biochem Biophys Res Commun 245: 684-690
    • (1998) Biochem Biophys Res Commun , vol.245 , pp. 684-690
    • Liu, Y.1    Casey, L.2    Pike, L.J.3
  • 26
    • 0035424240 scopus 로고    scopus 로고
    • PI(4,5)P(2) regulation of surface membrane traffic
    • Martin TF (2001) PI(4,5)P(2) regulation of surface membrane traffic. Curr Opin Cell Biol 13: 493-499
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 493-499
    • Martin, T.F.1
  • 27
    • 0028000605 scopus 로고
    • Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking
    • Mayor S, Rothberg KG, Maxfield FR (1994) Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science 264: 1948-1951
    • (1994) Science , vol.264 , pp. 1948-1951
    • Mayor, S.1    Rothberg, K.G.2    Maxfield, F.R.3
  • 28
    • 0344585437 scopus 로고    scopus 로고
    • Lipid rafts: Elusive or illusive?
    • Munro S (2003) Lipid rafts: elusive or illusive? Cell 115: 377-388
    • (2003) Cell , vol.115 , pp. 377-388
    • Munro, S.1
  • 30
    • 0034464348 scopus 로고    scopus 로고
    • Statistical evaluation of colocalization patterns in immunogold labeling experiments
    • Philimonenko AA, Janacek J, Hozak P (2000) Statistical evaluation of colocalization patterns in immunogold labeling experiments. J Struct Biol 132: 201-210
    • (2000) J Struct Biol , vol.132 , pp. 201-210
    • Philimonenko, A.A.1    Janacek, J.2    Hozak, P.3
  • 31
    • 0029926545 scopus 로고    scopus 로고
    • Localization and turnover of phosphatidyl-inositol 4,5-bisphosphate in caveolin-enriched membrane domains
    • Pike LJ, Casey L (1996) Localization and turnover of phosphatidyl- inositol 4,5-bisphosphate in caveolin-enriched membrane domains. J Biol Chem 271: 26453-26456
    • (1996) J Biol Chem , vol.271 , pp. 26453-26456
    • Pike, L.J.1    Casey, L.2
  • 32
    • 0032575524 scopus 로고    scopus 로고
    • Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover
    • Pike LJ, Miller JM (1998) Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover. J Biol Chem 273: 22298-22304
    • (1998) J Biol Chem , vol.273 , pp. 22298-22304
    • Pike, L.J.1    Miller, J.M.2
  • 34
    • 0037455589 scopus 로고    scopus 로고
    • Direct visualization of Ras proteins in spatially distinct cell surface microdomains
    • Prior IA, Muncke C, Parton RG, Hancock JF (2003) Direct visualization of Ras proteins in spatially distinct cell surface microdomains. J Cell Biol 160: 165-170
    • (2003) J Cell Biol , vol.160 , pp. 165-170
    • Prior, I.A.1    Muncke, C.2    Parton, R.G.3    Hancock, J.F.4
  • 35
    • 0033605718 scopus 로고    scopus 로고
    • The role of phosphoinositide 3-kinase lipid products in cell function
    • Rameh LE, Cantley LC (1999) The role of phosphoinositide 3-kinase lipid products in cell function. J Biol Chem 274: 8347-8350
    • (1999) J Biol Chem , vol.274 , pp. 8347-8350
    • Rameh, L.E.1    Cantley, L.C.2
  • 36
    • 0037201948 scopus 로고    scopus 로고
    • Membrane properties of sphingomyelins
    • Ramstedt B, Slotte JP (2002) Membrane properties of sphingomyelins. FEBS Lett 531: 33-37
    • (2002) FEBS Lett , vol.531 , pp. 33-37
    • Ramstedt, B.1    Slotte, J.P.2
  • 37
    • 0000135848 scopus 로고
    • Modelling spatial patterns
    • Ripley BD (1977) Modelling spatial patterns. J R Statist Soc B 39: 172-192
    • (1977) J R Statist Soc B , vol.39 , pp. 172-192
    • Ripley, B.D.1
  • 38
    • 0000135847 scopus 로고
    • Tests of randomness for spatial point patterns
    • Ripley BD (1979) Tests of randomness for spatial point patterns. J R Statist Soc B 41: 368-374
    • (1979) J R Statist Soc B , vol.41 , pp. 368-374
    • Ripley, B.D.1
  • 39
    • 0032931988 scopus 로고    scopus 로고
    • Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
    • Rodal SK, Skretting G, Garred O, Vilhardt F, van Deurs B, Sandvig K (1999) Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles. Mol Biol Cell 10: 961-974
    • (1999) Mol Biol Cell , vol.10 , pp. 961-974
    • Rodal, S.K.1    Skretting, G.2    Garred, O.3    Vilhardt, F.4    Van Deurs, B.5    Sandvig, K.6
  • 40
    • 0030949124 scopus 로고    scopus 로고
    • Functional rafts in cell membranes
    • Simons K, Ikonen E (1997) Functional rafts in cell membranes. Nature 387: S69-S72
    • (1997) Nature , vol.387
    • Simons, K.1    Ikonen, E.2
  • 41
    • 0034304851 scopus 로고    scopus 로고
    • Lipid rafts and signal transduction
    • Simons K, Toomre D (2000) Lipid rafts and signal transduction. Nat Rev Mol Cell Biol 1: 31-39
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 31-39
    • Simons, K.1    Toomre, D.2
  • 43
    • 0032510323 scopus 로고    scopus 로고
    • Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells
    • Stauffer TP, Ahn S, Meyer T (1998) Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells. Curr Biol 8: 343-346
    • (1998) Curr Biol , vol.8 , pp. 343-346
    • Stauffer, T.P.1    Ahn, S.2    Meyer, T.3
  • 45
    • 18844472606 scopus 로고    scopus 로고
    • Role of the Rab11-associated intracellular pool of receptors formed by constitutive endocytosis of the beta isoform of the thromboxane A2 receptor (TP beta)
    • Theriault C, Rochdi MD, Parent JL (2004) Role of the Rab11-associated intracellular pool of receptors formed by constitutive endocytosis of the beta isoform of the thromboxane A2 receptor (TP beta). Biochemistry 43: 5600-5607
    • (2004) Biochemistry , vol.43 , pp. 5600-5607
    • Theriault, C.1    Rochdi, M.D.2    Parent, J.L.3
  • 46
    • 0035805510 scopus 로고    scopus 로고
    • Monitoring agonist-induced phospholipase C activation in live cells by fluorescence resonance energy transfer
    • van der Wal J, Habets R, Varnai P, Balla T, Jalink K (2001) Monitoring agonist-induced phospholipase C activation in live cells by fluorescence resonance energy transfer. J Biol Chem 276: 15337-15344
    • (2001) J Biol Chem , vol.276 , pp. 15337-15344
    • Van Der Wal, J.1    Habets, R.2    Varnai, P.3    Balla, T.4    Jalink, K.5
  • 47
    • 0036736021 scopus 로고    scopus 로고
    • Agonist-induced PIP(2) hydrolysis inhibits cortical actin dynamics: Regulation at a global but not at a micrometer scale
    • van Rheenen J, Jalink K (2002) Agonist-induced PIP(2) hydrolysis inhibits cortical actin dynamics: regulation at a global but not at a micrometer scale. Mol Biol Cell 13: 3257-3267
    • (2002) Mol Biol Cell , vol.13 , pp. 3257-3267
    • Van Rheenen, J.1    Jalink, K.2
  • 48
    • 0032547744 scopus 로고    scopus 로고
    • Visualization of phosphoinositides that bind pleckstrin homology domains: Calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools
    • Varnai P, Balla T (1998) Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools. J Cell Biol 143: 501-510
    • (1998) J Cell Biol , vol.143 , pp. 501-510
    • Varnai, P.1    Balla, T.2
  • 49
    • 0033621359 scopus 로고    scopus 로고
    • Subcellular compartmentalization of activation and desensitization of responses mediated by NK2 neurokinin receptors
    • Vollmer JY, Alix P, Chollet A, Takeda K, Galzi JL (1999) Subcellular compartmentalization of activation and desensitization of responses mediated by NK2 neurokinin receptors. J Biol Chem. 274: 37915-37922
    • (1999) J Biol Chem , vol.274 , pp. 37915-37922
    • Vollmer, J.Y.1    Alix, P.2    Chollet, A.3    Takeda, K.4    Galzi, J.L.5
  • 50
    • 0036566427 scopus 로고    scopus 로고
    • Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1
    • Watt SA, Kular G, Fleming IN, Downes CP, Lucocq JM (2002) Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1. Biochem J 363: 657-666
    • (2002) Biochem J , vol.363 , pp. 657-666
    • Watt, S.A.1    Kular, G.2    Fleming, I.N.3    Downes, C.P.4    Lucocq, J.M.5
  • 51
    • 0032479158 scopus 로고    scopus 로고
    • Phosphatidylinositol 4-phosphate synthesis in immunoisolated caveolae-like vesicles and low buoyant density non-caveolar membranes
    • Waugh MG, Lawson D, Tan SK, Hsuan JJ (1998) Phosphatidylinositol 4-phosphate synthesis in immunoisolated caveolae-like vesicles and low buoyant density non-caveolar membranes. J Biol Chem 273: 17115-17121
    • (1998) J Biol Chem , vol.273 , pp. 17115-17121
    • Waugh, M.G.1    Lawson, D.2    Tan, S.K.3    Hsuan, J.J.4
  • 53
    • 0038311944 scopus 로고    scopus 로고
    • Phosphoinositide regulation of the actin cytoskeleton
    • Yin HL, Janmey PA (2003) Phosphoinositide regulation of the actin cytoskeleton. Annu. Rev Physiol 65: 761-789
    • (2003) Annu. Rev Physiol , vol.65 , pp. 761-789
    • Yin, H.L.1    Janmey, P.A.2
  • 54
    • 0037012847 scopus 로고    scopus 로고
    • Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells
    • Zacharias DA, Violin JD, Newton AC, Tsien RY (2002) Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells. Science 296: 913-916
    • (2002) Science , vol.296 , pp. 913-916
    • Zacharias, D.A.1    Violin, J.D.2    Newton, A.C.3    Tsien, R.Y.4


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