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Volumn 15, Issue 6, 2009, Pages 244-248

Diversity of moxifloxacin resistance during a nosocomial outbreak of a predominantly ribotype ARU 027 Clostridium difficile diarrhea

Author keywords

Clostridium difficile; gyrA; gyrB; MAMA; Moxifloxacin; PCR; QRDR; Quinolone; Resistance; SNP

Indexed keywords

ALANINE; ARGININE; ASPARAGINE; ASPARTIC ACID; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; DNA TOPOISOMERASE (ATP HYDROLYSING) A; GLUTAMATE DEHYDROGENASE; GLUTAMIC ACID; ISOLEUCINE; LYSINE; MOXIFLOXACIN; SERINE; THREONINE; VALINE;

EID: 70450267459     PISSN: 10759964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anaerobe.2009.09.009     Document Type: Article
Times cited : (16)

References (28)
  • 1
    • 0032901542 scopus 로고    scopus 로고
    • PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes
    • Stubss S.L.J., Brazier J.S., O'Neill G.L., and Duerden B.I. PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes. J Clin Microbiol 37 (1999) 461-463
    • (1999) J Clin Microbiol , vol.37 , pp. 461-463
    • Stubss, S.L.J.1    Brazier, J.S.2    O'Neill, G.L.3    Duerden, B.I.4
  • 3
    • 12144284570 scopus 로고    scopus 로고
    • A hospital outbreak of Clostridium difficile disease associated with isolates carrying binary toxin genes
    • McEllistrem M.C., Carman R.J., Gerding D.N., Genheimer C.W., and Zheng L. A hospital outbreak of Clostridium difficile disease associated with isolates carrying binary toxin genes. Clin Infect Dis 40 (2005) 265-272
    • (2005) Clin Infect Dis , vol.40 , pp. 265-272
    • McEllistrem, M.C.1    Carman, R.J.2    Gerding, D.N.3    Genheimer, C.W.4    Zheng, L.5
  • 5
    • 70450286473 scopus 로고    scopus 로고
    • High-level resistance to moxifloxacin and gatifloxacin associated with a novel mutation in gyrB in toxin-A-negative, toxin-B-positive Clostridium difficile
    • Drudy D., Quinn T., O'Mahony R., Kyne L., O'Gaora P., and Fanning S. High-level resistance to moxifloxacin and gatifloxacin associated with a novel mutation in gyrB in toxin-A-negative, toxin-B-positive Clostridium difficile. J Antimicrob Chemother 46 (2006) 3418-3421
    • (2006) J Antimicrob Chemother , vol.46 , pp. 3418-3421
    • Drudy, D.1    Quinn, T.2    O'Mahony, R.3    Kyne, L.4    O'Gaora, P.5    Fanning, S.6
  • 6
    • 34247260039 scopus 로고    scopus 로고
    • Isolation and characterisation of toxin A-negative, toxin B-positive Clostridium difficile in Dublin, Ireland
    • Drudy D., Harnedy N., Fanning S., O'Mahony R., and Kyne L. Isolation and characterisation of toxin A-negative, toxin B-positive Clostridium difficile in Dublin, Ireland. Clin Microbiol Infect 13 (2007) 298-304
    • (2007) Clin Microbiol Infect , vol.13 , pp. 298-304
    • Drudy, D.1    Harnedy, N.2    Fanning, S.3    O'Mahony, R.4    Kyne, L.5
  • 7
    • 40749109390 scopus 로고    scopus 로고
    • Increasing prevalence of toxin A-negative, toxin B-positive isolates of Clostridium difficile in Korea: impact on laboratory diagnosis
    • Kim H., Riley T.V., Kim M., Kim C.K., Yong D., Lee K., et al. Increasing prevalence of toxin A-negative, toxin B-positive isolates of Clostridium difficile in Korea: impact on laboratory diagnosis. J Clin Microbiol 46 (2008) 1116-1117
    • (2008) J Clin Microbiol , vol.46 , pp. 1116-1117
    • Kim, H.1    Riley, T.V.2    Kim, M.3    Kim, C.K.4    Yong, D.5    Lee, K.6
  • 8
    • 0033604532 scopus 로고    scopus 로고
    • Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals
    • Johnson S., Samore M.H., Farrow K.A., Killgore G.E., Tenover F.C., Lyras D., et al. Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals. N Engl J Med 341 (1999) 1645-1651
    • (1999) N Engl J Med , vol.341 , pp. 1645-1651
    • Johnson, S.1    Samore, M.H.2    Farrow, K.A.3    Killgore, G.E.4    Tenover, F.C.5    Lyras, D.6
  • 10
    • 0034924147 scopus 로고    scopus 로고
    • Resistance to moxifloxacin in toxigenic Clostridium difficile isolates is associated with mutations in gyrA
    • Ackermann G., Tang Y.J., Kueper R., Heisig P., Rodloff A.C., Silva Jr. J., et al. Resistance to moxifloxacin in toxigenic Clostridium difficile isolates is associated with mutations in gyrA. Antimicrob Agents Chemother 45 (2001) 2348-2353
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 2348-2353
    • Ackermann, G.1    Tang, Y.J.2    Kueper, R.3    Heisig, P.4    Rodloff, A.C.5    Silva Jr., J.6
  • 11
    • 0036840972 scopus 로고    scopus 로고
    • gyrA and gyrB mutations are implicated in cross-resistance to ciprofloxacin and moxifloxacin in Clostridium difficile
    • Dridi L., Tankovic J., Burghoffer B., Barbut F., and Petit J.C. gyrA and gyrB mutations are implicated in cross-resistance to ciprofloxacin and moxifloxacin in Clostridium difficile. Antimicrob Agents Chemother 46 (2002) 3418-3421
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3418-3421
    • Dridi, L.1    Tankovic, J.2    Burghoffer, B.3    Barbut, F.4    Petit, J.C.5
  • 12
    • 45249087419 scopus 로고    scopus 로고
    • Fluoroquinolone resistance in Clostridium difficile isolates from a prospective study of C. difficile infections in Europe
    • Spigaglia P., Barbanti F., Mastrantonio P., Brazier J.S., Barbut F., Delmée M., et al. Fluoroquinolone resistance in Clostridium difficile isolates from a prospective study of C. difficile infections in Europe. J Med Microbiol 57 (2008) 784-789
    • (2008) J Med Microbiol , vol.57 , pp. 784-789
    • Spigaglia, P.1    Barbanti, F.2    Mastrantonio, P.3    Brazier, J.S.4    Barbut, F.5    Delmée, M.6
  • 13
    • 0035206185 scopus 로고    scopus 로고
    • ADP-ribosylating binary toxin genes of Clostridium difficile strain CCUG 20309
    • Chang S.Y., and Song K.P. ADP-ribosylating binary toxin genes of Clostridium difficile strain CCUG 20309. DNA Seq 12 (2001) 115-120
    • (2001) DNA Seq , vol.12 , pp. 115-120
    • Chang, S.Y.1    Song, K.P.2
  • 14
    • 0028868816 scopus 로고
    • The toxigenic element of Clostridium difficile strain VPI 10463
    • Hammond G.A., and Johnson J.L. The toxigenic element of Clostridium difficile strain VPI 10463. Microb Pathog 19 (1995) 203-213
    • (1995) Microb Pathog , vol.19 , pp. 203-213
    • Hammond, G.A.1    Johnson, J.L.2
  • 16
    • 0034049543 scopus 로고    scopus 로고
    • Analysis of the pathogenicity locus in Clostridium difficile strains
    • Cohen S.H., Tang Y.J., and Silva Jr. J. Analysis of the pathogenicity locus in Clostridium difficile strains. J Infect Dis 181 (2000) 659-663
    • (2000) J Infect Dis , vol.181 , pp. 659-663
    • Cohen, S.H.1    Tang, Y.J.2    Silva Jr., J.3
  • 17
    • 0022520944 scopus 로고
    • Growth of Clostridium difficile and production of toxins A and B in complex and defined media
    • Haslam S.C., Ketley J.M., Mitchell T.J., Stephen J., Burdon D.W., and Candy D.C. Growth of Clostridium difficile and production of toxins A and B in complex and defined media. J Med Microbiol 21 (1986) 293-297
    • (1986) J Med Microbiol , vol.21 , pp. 293-297
    • Haslam, S.C.1    Ketley, J.M.2    Mitchell, T.J.3    Stephen, J.4    Burdon, D.W.5    Candy, D.C.6
  • 18
    • 33745550745 scopus 로고    scopus 로고
    • The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome
    • Sebaihia M., Wren B.W., Mullany P., Fairweather N.F., Minton N., Stabler R., et al. The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet 38 (2006) 779-786
    • (2006) Nat Genet , vol.38 , pp. 779-786
    • Sebaihia, M.1    Wren, B.W.2    Mullany, P.3    Fairweather, N.F.4    Minton, N.5    Stabler, R.6
  • 19
    • 0023747353 scopus 로고
    • Actin-specific ADP-ribosyltransferase produced by a Clostridium difficile strain
    • Popoff M.R., Rubin E.J., Gill D.M., and Boquet P. Actin-specific ADP-ribosyltransferase produced by a Clostridium difficile strain. Infect Immun 56 (1988) 2299-2306
    • (1988) Infect Immun , vol.56 , pp. 2299-2306
    • Popoff, M.R.1    Rubin, E.J.2    Gill, D.M.3    Boquet, P.4
  • 20
    • 0031004306 scopus 로고    scopus 로고
    • Production of a complete binary toxin (actin-specific ADP-ribosyltransferase) by Clostridium difficile CD196
    • Perelle S., Gibert M., Bourlioux P., Corthier G., and Popoff M.R. Production of a complete binary toxin (actin-specific ADP-ribosyltransferase) by Clostridium difficile CD196. Infect Immun 65 (1997) 1402-1407
    • (1997) Infect Immun , vol.65 , pp. 1402-1407
    • Perelle, S.1    Gibert, M.2    Bourlioux, P.3    Corthier, G.4    Popoff, M.R.5
  • 21
    • 0344766074 scopus 로고    scopus 로고
    • A novel cytotoxin from Clostridium difficile serogroup F is a functional hybrid between two other large clostridial cytotoxins
    • Chaves-Olarte E., Low P., Freer E., Norlin T., Weidmann M., von Eichel-Streiber C., et al. A novel cytotoxin from Clostridium difficile serogroup F is a functional hybrid between two other large clostridial cytotoxins. J Biol Chem 274 (1999) 11046-11052
    • (1999) J Biol Chem , vol.274 , pp. 11046-11052
    • Chaves-Olarte, E.1    Low, P.2    Freer, E.3    Norlin, T.4    Weidmann, M.5    von Eichel-Streiber, C.6
  • 22
    • 0033891753 scopus 로고    scopus 로고
    • Genetic Characterization of Toxin A-Negative, Toxin B-Positive Clostridium difficile Isolates by PCR
    • Moncrief J.S., Zheng L., Neville L.M., and Lyerly D.M. Genetic Characterization of Toxin A-Negative, Toxin B-Positive Clostridium difficile Isolates by PCR. J Clin Microbiol 38 (2000) 3072-3075
    • (2000) J Clin Microbiol , vol.38 , pp. 3072-3075
    • Moncrief, J.S.1    Zheng, L.2    Neville, L.M.3    Lyerly, D.M.4
  • 23
    • 0025765660 scopus 로고
    • Purification and characterization of toxin B from a strain of Clostridium difficile that does not produce toxin A
    • Torres J.F. Purification and characterization of toxin B from a strain of Clostridium difficile that does not produce toxin A. J Med Microbiol 35 (1991) 40-44
    • (1991) J Med Microbiol , vol.35 , pp. 40-44
    • Torres, J.F.1
  • 24
    • 12944281047 scopus 로고    scopus 로고
    • Alterations in DNA gyrase and topoisomerase IV in resistant mutants of Clostridium perfringens found after in vitro treatment with fluoroquinolones
    • Rafii F., Park M., and Novak J.S. Alterations in DNA gyrase and topoisomerase IV in resistant mutants of Clostridium perfringens found after in vitro treatment with fluoroquinolones. Antimicrob Agents Chemother 49 (2005) 488-492
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 488-492
    • Rafii, F.1    Park, M.2    Novak, J.S.3
  • 25
    • 67349095083 scopus 로고    scopus 로고
    • Characterization of Clostridium difficile strains isolated from immunosuppressed inpatients in a hospital in Rio de Janeiro, Brazil
    • Epub ahead of print
    • Balassiano I.T., Miranda K.R., Boente R.F., Pauer H., Oliveira I.C., Santos-Filho J., et al. Characterization of Clostridium difficile strains isolated from immunosuppressed inpatients in a hospital in Rio de Janeiro, Brazil. Anaerobe Jan 13 (2009) Epub ahead of print
    • (2009) Anaerobe , vol.Jan 13
    • Balassiano, I.T.1    Miranda, K.R.2    Boente, R.F.3    Pauer, H.4    Oliveira, I.C.5    Santos-Filho, J.6
  • 26
    • 25144469664 scopus 로고    scopus 로고
    • Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe
    • Warny M., Pepin J., Fang A., Killgore G., Thompson A., Brazier J., et al. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet 366 9491 (2005) 1079-1084
    • (2005) Lancet , vol.366 , Issue.9491 , pp. 1079-1084
    • Warny, M.1    Pepin, J.2    Fang, A.3    Killgore, G.4    Thompson, A.5    Brazier, J.6
  • 27
    • 33847416012 scopus 로고    scopus 로고
    • gyrA mutations in fluoroquinolone-resistant Clostridium difficile PCR-027
    • Drudy D., Kyne L., O'Mahony R., and Fanning S. gyrA mutations in fluoroquinolone-resistant Clostridium difficile PCR-027. Emerg Infect Dis 13 (2007) 504-505
    • (2007) Emerg Infect Dis , vol.13 , pp. 504-505
    • Drudy, D.1    Kyne, L.2    O'Mahony, R.3    Fanning, S.4
  • 28
    • 0034607782 scopus 로고    scopus 로고
    • Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile
    • Stubbs S., Rupnik M., Gibert M., Brazier J., Duerden B., and Popoff M. Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile. FEMS Microbiol Lett 186 (2000) 307-312
    • (2000) FEMS Microbiol Lett , vol.186 , pp. 307-312
    • Stubbs, S.1    Rupnik, M.2    Gibert, M.3    Brazier, J.4    Duerden, B.5    Popoff, M.6


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