Selective striatal mtDNA depletion in end-stage Huntington's disease R6/2 mice

Experimental Neurology

Volumn 266, Issue , 2015, Pages 22-29

  Hering, Tanja ^a   Birth, Nathalie ^a   Taanman, Jan Willem ^b   Orth, Michael ^a  

^a UNIVERSITY OF ULM   (Germany)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Mitochondrial biogenesis; Mitochondrial respiratory chain assembly; MtDNA depletion; PGC 1 ; TFAM

Indexed keywords

ADENOSINE TRIPHOSPHATE; CITRATE SYNTHASE; HUNTINGTIN; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; BRAIN CORTEX; COMPARATIVE STUDY; CONTROLLED STUDY; CORPUS STRIATUM; DNA TRANSCRIPTION; ENZYME ACTIVITY; GENE DOSAGE; HUNTINGTON CHOREA; MITOCHONDRIAL DNA DEPLETION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; RESPIRATORY CHAIN; RESPIRATORY CHAIN COMPLEX I; RESPIRATORY CHAIN COMPLEX II; RESPIRATORY CHAIN COMPLEX III; RESPIRATORY CHAIN COMPLEX IV; SPECTROPHOTOMETRY; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; ELECTRON TRANSPORT; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MUTATION; NEOSTRIATUM; PATHOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; CITRATE (SI)-SYNTHASE; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT; GENE DOSAGE; HUNTINGTON DISEASE; MICE; MUTATION; NEOSTRIATUM; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84922996944     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2015.02.004     Document Type: Article

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