Metabolic and glutamatergic disturbances in the Huntington's disease transgenic mouse

Annals of the New York Academy of Sciences

Volumn 893, Issue , 1999, Pages 298-300

  Higgins, Donald S ^a   Hoyt, Kari R ^a   Baic, Corinne ^a   Vensel, Jessica ^a   Sulka, Matthew ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE RECEPTOR;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; AUTORADIOGRAPHY; CONFERENCE PAPER; ENZYME HISTOCHEMISTRY; HUNTINGTON CHOREA; METABOLIC DISORDER; MOUSE; NONHUMAN; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 0033378683     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07841.x     Document Type: Conference Paper

References (9)

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2. 2. Bates, G.P. et al. 1997. Transgenic models of Huntington's disease. Human Molec. Gen. 6(10): 1633-1637.
3. 3. Jenkins, B.G. et al. 1993. Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy. Neurology 43: 2689-2695.
4. 4. Parker, W.D. et al. 1990. Evidence for a defect in NADH:ubiquinone oxidoreductase (complex I) in Huntington's disease. Neurology 40: 1231-1234.
5. 5. Brennan, W.A., E.D. Bird & J.R. Aprille. 1985. Regional mitochondrial respiratory activity in Huntington's disease brain. J. Neurochem. 44: 1948-1950.
6. 6. Tabrizi, S.J. et al. 1999. Biochemical abnormalities and excitotoxicity in Huntington's disease brain. Ann. Neurol. 45: 25-32.
7. 7. Tabrizi, S.J. et al. 1998. Mitochondrial biochemical features of the R6/2 transgenic mouse model of Huntington's disease. Movement Disorders 13 (Suppl. 2): 153.
8. 8. Cha, J.-H.J. et al. 1998. Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human Huntington disease gene. Proc. Natl. Acad. Sci. USA 95: 6480-6485.
9. 9. Hurlbert, M.S. et al. 1999. Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes. Diabetes 48: 649-651.